<?xml version="1.0" encoding="UTF-8"?>
<STUDY_SET xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <STUDY center_name="GEO" alias="GSE186293" accession="SRP342461">
    <IDENTIFIERS>
      <PRIMARY_ID>SRP342461</PRIMARY_ID>
      <EXTERNAL_ID namespace="BioProject" label="primary">PRJNA773178</EXTERNAL_ID>
      <EXTERNAL_ID namespace="GEO">GSE186293</EXTERNAL_ID>
    </IDENTIFIERS>
    <DESCRIPTOR>
      <STUDY_TITLE>Transcriptomic profiling of human induced pluripotent stem cells derived cardiomyocytes (hiPSC-CMs) and cardiac progentiors (hiPSC-CPs) from tetralogy of Fallot (TOF) patients with DiGeorge Syndrome (DG) and without DiGeorge Syndrome (ND)</STUDY_TITLE>
      <STUDY_TYPE existing_study_type="Transcriptome Analysis"/>
      <STUDY_ABSTRACT>DG accounts for most of the identifiable cases of TOF. Exploring and comparing the transcriptome of hiPSC-CMs and hiPSC-CPs from TOF-DG and TOF-ND could provide a bettering understanding on TOF. Overall design: Day 7,8 and 11 hiPSC-CPs undergoing in vitro cardiac differentiation derived from 2 control-, 1 TOF-DG- and 1 TOF-ND-hiPSC lines. Day22 hiPSC-CMs (fabricated into cardiac anisotropic sheets, CAS) derived from 2 control-, 2 TOF-DG- and 2 TOF-ND-hiPSC lines.</STUDY_ABSTRACT>
      <CENTER_PROJECT_NAME>GSE186293</CENTER_PROJECT_NAME>
    </DESCRIPTOR>
    <STUDY_LINKS>
      <STUDY_LINK>
        <XREF_LINK>
          <DB>pubmed</DB>
          <ID>37740059</ID>
        </XREF_LINK>
      </STUDY_LINK>
    </STUDY_LINKS>
  </STUDY>
</STUDY_SET>
