SRP343383 PRJNA774951 Transcriptome analysis of mouse TG2 KO and WT beige cells Although TG2+/+ and TG2-/- preadipocytes differentiate similarly, the mitochondria of the knock-out beige cells have multiple impairments including an altered electron transport system generating lower electrochemical potential difference, with reduced oxygen consumption and UCP1 expression, and a higher portion of fragmented mitochondria functioning weaker.