SRP344210 PRJNA777234 GSE186991 CUT&RUN of TAF4b and H3K4me3 in E16.5 oocytes Research has shown that Taf4b-deficient female mice display excessive perinatal germ cell death, delayed germ cell cyst breakdown, and increased chromosome asynapsis. Therefore, we hypothesized that TAF4b, as part of TFIID, regulates oogenesis and meiotic gene programs. However, the direct targets of TAF4b have not been thoroughly explored. Therefore, we performed Cleavage Under Targets and Release Using Nuclease (CUT&RUN) in E16.5 mouse oocytes. Overall design: E16.5 oocytes were obtained through fluorescence-activated cell sorting (FACS) from Oct4-EGFP embryonic mice GSE186991 pubmed 35043944