SRS12036734 SAMN26028611 9606 Homo sapiens bioproject 805222 PRJNA805222 isolate N/A age N/A biomaterial_provider NEI sex male tissue whole blood Global_ID 25669 Family 137 Pedigree_ID IV-1 AMD_phenotype_modified_AREDS can't grade Worse_known_VA_OD 20/30 -1 Worse_known_VA_OS 20/25 -3 rs139498867_C8B_A_risk C/C C8A_or_C8B_genotyping_method Sanger rs1061170_CFH_C_risk not done rs10490924_ARMS2_T_risk G/G Smoking_status never BMI unknown Eye_health_supplements_AREDS_lutein_or_zeaxanthin unknown History_of_glaucoma unknown History_of_cataract_surgery unkown History_of_diabetes unknown Hypertension_medication no Cholesterol_lowering_medication unknown Any_cardiovascular_event unknown BioSampleModel Human SRS12036735 SAMN26028612 9606 Homo sapiens bioproject 805222 PRJNA805222 isolate N/A age 70 biomaterial_provider NEI sex female tissue whole blood Global_ID 25700 Family 137 Pedigree_ID IV-4 AMD_phenotype_modified_AREDS 2 Drusen_OD Medium Drusen_OS No drusen Worse_known_VA_OD 20/20 Worse_known_VA_OS 20/25 rs139498867_C8B_A_risk C/C C8A_or_C8B_genotyping_method Sanger rs1061170_CFH_C_risk C/T rs10490924_ARMS2_T_risk G/G Smoking_status never BMI 26.152242149207478 Eye_health_supplements_AREDS_lutein_or_zeaxanthin no History_of_glaucoma no History_of_cataract_surgery yes (OU) History_of_diabetes no Hypertension_medication no Cholesterol_lowering_medication no Any_cardiovascular_event no BioSampleModel Human SRS12036736 SAMN26028621 9606 Homo sapiens bioproject 805222 PRJNA805222 isolate N/A age 87 biomaterial_provider NEI sex male tissue whole blood Global_ID 26795 Family 169 Pedigree_ID II-3 AMD_phenotype_modified_AREDS 5 Drusen_OD AAMD-GA Drusen_OS AAMD-GA Photo_notes OS: GA, bullseye, ? Dystrophy rs143908758_C8A_A AI_risk G/G C8A_or_C8B_genotyping_method Sanger rs1061170_CFH_C_risk C/T rs10490924_ARMS2_T_risk G/T Smoking_status never BMI 25.104353820343857 Eye_health_supplements_AREDS_lutein_or_zeaxanthin unknown History_of_glaucoma no History_of_cataract_surgery unkown History_of_diabetes unknown Hypertension_medication no Cholesterol_lowering_medication unknown Any_cardiovascular_event unknown BioSampleModel Human SRS12036737 SAMN26028622 9606 Homo sapiens bioproject 805222 PRJNA805222 isolate N/A age 74 biomaterial_provider NEI sex female tissue whole blood Global_ID 26801 Family 169 Pedigree_ID III-4 AMD_phenotype_modified_AREDS 3 Drusen_OD Large Drusen_OS DPED Worse_known_VA_OD 20/40 +2 Worse_known_VA_OS 20/50 -2 rs143908758_C8A_A AI_risk G/G C8A_or_C8B_genotyping_method Sanger rs1061170_CFH_C_risk C/C rs10490924_ARMS2_T_risk T/T Smoking_status former BMI 21.133689139449288 Eye_health_supplements_AREDS_lutein_or_zeaxanthin yes History_of_glaucoma no History_of_cataract_surgery yes (OU) History_of_diabetes no Hypertension_medication yes Cholesterol_lowering_medication yes Any_cardiovascular_event no BioSampleModel Human SRS12036738 SAMN26028623 9606 Homo sapiens bioproject 805222 PRJNA805222 isolate N/A age 58 biomaterial_provider NEI sex female tissue whole blood Global_ID 26826 Family 169 Pedigree_ID IV-1 AMD_phenotype_modified_AREDS 3 Drusen_OD Large Drusen_OS Small rs143908758_C8A_A AI_risk G/G C8A_or_C8B_genotyping_method Sanger rs1061170_CFH_C_risk not done rs10490924_ARMS2_T_risk not done Smoking_status former BMI 34.74993139160385 Eye_health_supplements_AREDS_lutein_or_zeaxanthin no History_of_glaucoma no History_of_cataract_surgery no History_of_diabetes no Hypertension_medication no Cholesterol_lowering_medication no Any_cardiovascular_event no BioSampleModel Human SRS12036739 SAMN26028624 9606 Homo sapiens bioproject 805222 PRJNA805222 isolate N/A age 80 biomaterial_provider NEI sex male tissue whole blood Global_ID 27911 Family 190 Pedigree_ID II-1 AMD_phenotype_modified_AREDS 3 Drusen_OD DPED Drusen_OS DPED Photo_notes extensive Worse_known_VA_OD 20/30 Worse_known_VA_OS 20/50 rs143908758_C8A_A AI_risk G/G C8A_or_C8B_genotyping_method Sanger rs1061170_CFH_C_risk C/T rs10490924_ARMS2_T_risk G/T Smoking_status unknown BMI unknown Eye_health_supplements_AREDS_lutein_or_zeaxanthin unknown History_of_glaucoma unknown History_of_cataract_surgery unkown History_of_diabetes unknown Hypertension_medication unknown Cholesterol_lowering_medication unknown Any_cardiovascular_event unknown BioSampleModel Human SRS12036740 SAMN26028625 9606 Homo sapiens bioproject 805222 PRJNA805222 isolate N/A age 85 biomaterial_provider NEI sex female tissue whole blood Global_ID 35215 Family 37 Pedigree_ID II-6 AMD_phenotype_modified_AREDS 1 Drusen_OD No drusen Drusen_OS No drusen Worse_known_VA_OD 20/25 Worse_known_VA_OS 20/70 rs139498867_C8B_A_risk C/C C8A_or_C8B_genotyping_method Sanger rs1061170_CFH_C_risk C/T rs10490924_ARMS2_T_risk G/G Smoking_status never BMI 25.793085170194008 Eye_health_supplements_AREDS_lutein_or_zeaxanthin no History_of_glaucoma no History_of_cataract_surgery no History_of_diabetes no Hypertension_medication no Cholesterol_lowering_medication no Any_cardiovascular_event no BioSampleModel Human SRS12036741 SAMN26028626 9606 Homo sapiens bioproject 805222 PRJNA805222 isolate N/A age 66 biomaterial_provider NEI sex female tissue whole blood Global_ID 35223 Family 37 Pedigree_ID III-6 AMD_phenotype_modified_AREDS 3 Drusen_OD Large Drusen_OS Large Worse_known_VA_OD 20/20 Worse_known_VA_OS 20/25 rs139498867_C8B_A_risk C/A C8A_or_C8B_genotyping_method Sanger rs1061170_CFH_C_risk C/T rs10490924_ARMS2_T_risk G/T Smoking_status former BMI 20.597741590990996 Eye_health_supplements_AREDS_lutein_or_zeaxanthin yes History_of_glaucoma no History_of_cataract_surgery no History_of_diabetes no Hypertension_medication no Cholesterol_lowering_medication no Any_cardiovascular_event no BioSampleModel Human SRS12036742 SAMN26028628 9606 Homo sapiens bioproject 805222 PRJNA805222 isolate N/A age 58 biomaterial_provider NEI sex male tissue whole blood Global_ID 35229 Family 37 Pedigree_ID III-11 AMD_phenotype_modified_AREDS 1 Drusen_OD No drusen Drusen_OS No drusen Worse_known_VA_OD 20/20 Worse_known_VA_OS 20/25 rs139498867_C8B_A_risk C/C C8A_or_C8B_genotyping_method Sanger rs1061170_CFH_C_risk C/T rs10490924_ARMS2_T_risk G/T Smoking_status never BMI 26.5444637210703 Eye_health_supplements_AREDS_lutein_or_zeaxanthin unknown History_of_glaucoma no History_of_cataract_surgery unkown History_of_diabetes unknown Hypertension_medication unknown Cholesterol_lowering_medication unknown Any_cardiovascular_event no BioSampleModel Human SRS12036743 SAMN26028627 9606 Homo sapiens bioproject 805222 PRJNA805222 isolate N/A age 82 biomaterial_provider NEI sex female tissue whole blood Global_ID 35228 Family 37 Pedigree_ID III-3 AMD_phenotype_modified_AREDS 3 Drusen_OD Large Drusen_OS No drusen Worse_known_VA_OD 20/25 Worse_known_VA_OS 20/30 rs139498867_C8B_A_risk C/C C8A_or_C8B_genotyping_method Sanger rs1061170_CFH_C_risk C/T rs10490924_ARMS2_T_risk G/G Smoking_status never BMI 18.776864560783796 Eye_health_supplements_AREDS_lutein_or_zeaxanthin yes History_of_glaucoma unknown History_of_cataract_surgery unkown History_of_diabetes no Hypertension_medication yes Cholesterol_lowering_medication unknown Any_cardiovascular_event no BioSampleModel Human SRS12036744 SAMN26028629 9606 Homo sapiens bioproject 805222 PRJNA805222 isolate N/A age 89 biomaterial_provider NEI sex male tissue whole blood Global_ID 35256 Family 37 Pedigree_ID III-1 AMD_phenotype_modified_AREDS 1 Drusen_OD No drusen Drusen_OS No drusen Photo_notes thin RPE Worse_known_VA_OD 20/40 Worse_known_VA_OS 20/40 rs139498867_C8B_A_risk C/C C8A_or_C8B_genotyping_method Sanger rs1061170_CFH_C_risk T/T rs10490924_ARMS2_T_risk G/T Smoking_status never BMI 24.03069852282283 Eye_health_supplements_AREDS_lutein_or_zeaxanthin unknown History_of_glaucoma no History_of_cataract_surgery unkown History_of_diabetes unknown Hypertension_medication unknown Cholesterol_lowering_medication unknown Any_cardiovascular_event unknown BioSampleModel Human SRS12036745 SAMN26028630 9606 Homo sapiens bioproject 805222 PRJNA805222 isolate N/A age 58 biomaterial_provider NEI sex male tissue whole blood Global_ID 35258 Family 37 Pedigree_ID IV-1 AMD_phenotype_modified_AREDS 1 Drusen_OD No drusen Drusen_OS Small Worse_known_VA_OD 20/30 Worse_known_VA_OS 20/20 rs139498867_C8B_A_risk C/A C8A_or_C8B_genotyping_method Sanger rs1061170_CFH_C_risk C/T rs10490924_ARMS2_T_risk G/T Smoking_status never BMI 25.0902531314129 Eye_health_supplements_AREDS_lutein_or_zeaxanthin no History_of_glaucoma no History_of_cataract_surgery unkown History_of_diabetes no Hypertension_medication yes Cholesterol_lowering_medication no Any_cardiovascular_event yes (stroke) BioSampleModel Human SRS12036746 SAMN26028613 9606 Homo sapiens bioproject 805222 PRJNA805222 isolate N/A age 79 biomaterial_provider NEI sex female tissue whole blood Global_ID 25701 Family 137 Pedigree_ID IV-5 AMD_phenotype_modified_AREDS 2 Drusen_OD Medium Drusen_OS Medium rs139498867_C8B_A_risk C/A C8A_or_C8B_genotyping_method Sanger rs1061170_CFH_C_risk not done rs10490924_ARMS2_T_risk G/G Smoking_status never BMI 28.836838227387393 Eye_health_supplements_AREDS_lutein_or_zeaxanthin yes History_of_glaucoma unknown History_of_cataract_surgery no History_of_diabetes no Hypertension_medication no Cholesterol_lowering_medication no Any_cardiovascular_event no BioSampleModel Human SRS12036747 SAMN26028631 9606 Homo sapiens bioproject 805222 PRJNA805222 isolate N/A age 63 biomaterial_provider NEI sex female tissue whole blood Global_ID 35261 Family 37 Pedigree_ID IV-3 AMD_phenotype_modified_AREDS 1 Drusen_OD Small Drusen_OS No drusen rs139498867_C8B_A_risk C/C C8A_or_C8B_genotyping_method Sanger rs1061170_CFH_C_risk not done rs10490924_ARMS2_T_risk not done Smoking_status never BMI 23.56742751818116 Eye_health_supplements_AREDS_lutein_or_zeaxanthin no History_of_glaucoma no History_of_cataract_surgery no History_of_diabetes no Hypertension_medication yes Cholesterol_lowering_medication no Any_cardiovascular_event no BioSampleModel Human SRS12036748 SAMN26028633 9606 Homo sapiens bioproject 805222 PRJNA805222 isolate N/A age 85 biomaterial_provider NEI sex male tissue whole blood Global_ID 37497 Family 72 Pedigree_ID II-4 AMD_phenotype_modified_AREDS 5 Drusen_OD AAMD-NV Drusen_OS AAMD-NV Photo_notes OD: GA; OS: Ex, significant nuclear sclerosis Worse_known_VA_OD 3/200 Worse_known_VA_OS LP rs139498867_C8B_A_risk C/A C8A_or_C8B_genotyping_method Sanger rs1061170_CFH_C_risk C/T rs10490924_ARMS2_T_risk T/T Smoking_status never BMI 26.625490875174222 Eye_health_supplements_AREDS_lutein_or_zeaxanthin unknown History_of_glaucoma no History_of_cataract_surgery unkown History_of_diabetes unknown Hypertension_medication no Cholesterol_lowering_medication unknown Any_cardiovascular_event unknown BioSampleModel Human SRS12036749 SAMN26028632 9606 Homo sapiens bioproject 805222 PRJNA805222 isolate N/A age 52 biomaterial_provider NEI sex female tissue whole blood Global_ID 35262 Family 37 Pedigree_ID IV-2 AMD_phenotype_modified_AREDS 1 Drusen_OD No drusen Drusen_OS Small Photo_notes flecks OU, probably ERM Worse_known_VA_OD 20/40 Worse_known_VA_OS 20/20 rs139498867_C8B_A_risk C/C C8A_or_C8B_genotyping_method Sanger rs1061170_CFH_C_risk C/T rs10490924_ARMS2_T_risk G/G Smoking_status never BMI unkown Eye_health_supplements_AREDS_lutein_or_zeaxanthin unknown History_of_glaucoma unknown History_of_cataract_surgery unkown History_of_diabetes unknown Hypertension_medication unknown Cholesterol_lowering_medication unknown Any_cardiovascular_event no BioSampleModel Human SRS12036750 SAMN26028634 9606 Homo sapiens bioproject 805222 PRJNA805222 isolate N/A age 79 biomaterial_provider NEI sex male tissue whole blood Global_ID 37520 Family 72 Pedigree_ID III-1 AMD_phenotype_modified_AREDS 3 Drusen_OD Large Drusen_OS Large Photo_notes Age 68, Medium OU Worse_known_VA_OD 20/30 -3 Worse_known_VA_OS 20/25 -3 rs139498867_C8B_A_risk C/C C8A_or_C8B_genotyping_method Sanger rs1061170_CFH_C_risk C/T rs10490924_ARMS2_T_risk G/T Smoking_status never BMI 25.842717168001023 Eye_health_supplements_AREDS_lutein_or_zeaxanthin yes History_of_glaucoma no History_of_cataract_surgery no History_of_diabetes no Hypertension_medication no Cholesterol_lowering_medication no Any_cardiovascular_event no BioSampleModel Human SRS12036751 SAMN26028635 9606 Homo sapiens bioproject 805222 PRJNA805222 isolate N/A age 66 biomaterial_provider NEI sex male tissue whole blood Global_ID 37521 Family 72 Pedigree_ID III-2 AMD_phenotype_modified_AREDS 2 Drusen_OD Medium Drusen_OS Medium Photo_notes OU: multiple medium rs139498867_C8B_A_risk C/C C8A_or_C8B_genotyping_method Sanger rs1061170_CFH_C_risk not done rs10490924_ARMS2_T_risk G/T Smoking_status former BMI 23.674791967441077 Eye_health_supplements_AREDS_lutein_or_zeaxanthin yes History_of_glaucoma no History_of_cataract_surgery no History_of_diabetes no Hypertension_medication no Cholesterol_lowering_medication no Any_cardiovascular_event no BioSampleModel Human SRS12036752 SAMN26028614 9606 Homo sapiens bioproject 805222 PRJNA805222 isolate N/A age 56 biomaterial_provider NEI sex female tissue whole blood Global_ID 25707 Family 137 Pedigree_ID IV-6 AMD_phenotype_modified_AREDS 3 Drusen_OD Large Drusen_OS Large rs139498867_C8B_A_risk C/A C8A_or_C8B_genotyping_method Sanger rs1061170_CFH_C_risk C/T rs10490924_ARMS2_T_risk G/G Smoking_status never BMI 32.61309085240241 Eye_health_supplements_AREDS_lutein_or_zeaxanthin unknown History_of_glaucoma unknown History_of_cataract_surgery unkown History_of_diabetes unknown Hypertension_medication no Cholesterol_lowering_medication unknown Any_cardiovascular_event yes (heart attack) BioSampleModel Human SRS12036753 SAMN26028615 9606 Homo sapiens bioproject 805222 PRJNA805222 isolate N/A age 70 biomaterial_provider NEI sex female tissue whole blood Global_ID 25716 Family 137 Pedigree_ID IV-8 AMD_phenotype_modified_AREDS 4 Drusen_OD Large Drusen_OS AAMD-NV Worse_known_VA_OD 20/20 Worse_known_VA_OS 20/25 rs139498867_C8B_A_risk C/C C8A_or_C8B_genotyping_method Sanger rs1061170_CFH_C_risk C/T rs10490924_ARMS2_T_risk G/T Smoking_status never BMI 32.48798729691557 Eye_health_supplements_AREDS_lutein_or_zeaxanthin yes History_of_glaucoma no History_of_cataract_surgery no History_of_diabetes no Hypertension_medication no Cholesterol_lowering_medication no Any_cardiovascular_event no BioSampleModel Human SRS12036754 SAMN26028616 9606 Homo sapiens bioproject 805222 PRJNA805222 isolate N/A age 65 biomaterial_provider NEI sex female tissue whole blood Global_ID 25717 Family 137 Pedigree_ID IV-9 AMD_phenotype_modified_AREDS 2 Drusen_OD No drusen Drusen_OS Medium Worse_known_VA_OD 20/25 Worse_known_VA_OS 20/20 rs139498867_C8B_A_risk C/A C8A_or_C8B_genotyping_method Sanger rs1061170_CFH_C_risk not done rs10490924_ARMS2_T_risk G/T Smoking_status never BMI 30.896612386486495 Eye_health_supplements_AREDS_lutein_or_zeaxanthin no History_of_glaucoma no History_of_cataract_surgery no History_of_diabetes no Hypertension_medication no Cholesterol_lowering_medication no Any_cardiovascular_event no BioSampleModel Human SRS12036755 SAMN26028617 9606 Homo sapiens bioproject 805222 PRJNA805222 isolate N/A age N/A biomaterial_provider NEI sex female tissue whole blood Global_ID 25718 Family 137 Pedigree_ID IV-10 rs139498867_C8B_A_risk C/A C8A_or_C8B_genotyping_method Sanger rs1061170_CFH_C_risk not done rs10490924_ARMS2_T_risk not done Smoking_status never BMI 39.47900471606608 Eye_health_supplements_AREDS_lutein_or_zeaxanthin no History_of_glaucoma no History_of_cataract_surgery no History_of_diabetes yes Hypertension_medication yes Cholesterol_lowering_medication yes Any_cardiovascular_event no BioSampleModel Human SRS12036756 SAMN26028619 9606 Homo sapiens bioproject 805222 PRJNA805222 isolate N/A age 80 biomaterial_provider NEI sex female tissue whole blood Global_ID 25750 Family 137 Pedigree_ID III-13 AMD_phenotype_modified_AREDS 3 Drusen_OD No drusen Drusen_OS Large Worse_known_VA_OD 20/20 Worse_known_VA_OS 20/20 rs139498867_C8B_A_risk C/C C8A_or_C8B_genotyping_method Sanger rs1061170_CFH_C_risk C/C rs10490924_ARMS2_T_risk G/T Smoking_status never BMI 23.296980153723624 Eye_health_supplements_AREDS_lutein_or_zeaxanthin unknown History_of_glaucoma unknown History_of_cataract_surgery unkown History_of_diabetes unknown Hypertension_medication no Cholesterol_lowering_medication unknown Any_cardiovascular_event no BioSampleModel Human SRS12036757 SAMN26028618 9606 Homo sapiens bioproject 805222 PRJNA805222 isolate N/A age 80 biomaterial_provider NEI sex female tissue whole blood Global_ID 25723 Family 137 Pedigree_ID III-12 AMD_phenotype_modified_AREDS 4 Drusen_OD Large Drusen_OS AAMD-GA Worse_known_VA_OD 20/50 Worse_known_VA_OS 20/60 rs139498867_C8B_A_risk C/C C8A_or_C8B_genotyping_method Sanger rs1061170_CFH_C_risk C/T rs10490924_ARMS2_T_risk G/G Smoking_status never BMI 17.754282314120186 Eye_health_supplements_AREDS_lutein_or_zeaxanthin unknown History_of_glaucoma no History_of_cataract_surgery unkown History_of_diabetes unknown Hypertension_medication no Cholesterol_lowering_medication unknown Any_cardiovascular_event no BioSampleModel Human SRS12036758 SAMN26028620 9606 Homo sapiens bioproject 805222 PRJNA805222 isolate N/A age 80 biomaterial_provider NEI sex female tissue whole blood Global_ID 26791 Family 169 Pedigree_ID II-4 AMD_phenotype_modified_AREDS 4 Drusen_OD Large Drusen_OS AAMD-NV Photo_notes OD: 700 um drusen Worse_known_VA_OD 20/30 +2 Worse_known_VA_OS CF rs143908758_C8A_A AI_risk G/G C8A_or_C8B_genotyping_method Sanger rs1061170_CFH_C_risk C/T rs10490924_ARMS2_T_risk G/T Smoking_status never BMI 28.342437072881204 Eye_health_supplements_AREDS_lutein_or_zeaxanthin yes History_of_glaucoma unknown History_of_cataract_surgery unkown History_of_diabetes no Hypertension_medication no Cholesterol_lowering_medication unknown Any_cardiovascular_event no BioSampleModel Human