SRX15039996 GSM6071685_r1 SRP372715 PRJNA833072 SRS12786605 GSM6071685 GSM6071685 ATAC-seq GENOMIC other MinElute (before PCR, Qiagen) and AMPure XP (after PCR, Beckman Coulter) were used for DNA purification. Cells were lysed with CSK buffer (10 mM PIPES pH 6.8, 100 mM NaCl, 300 mM sucrose, 3 mM MgCl2, 0.1% Triton X-100). Nuclei were treated with Tn5 Transposase (Illumina). The total of 8 PCR cycles were performed to recover and amplify the DNA fragments at open chromatin. NextSeq 500 SRX15039997 GSM6071686_r1 SRP372715 PRJNA833072 SRS12786606 GSM6071686 GSM6071686 ATAC-seq GENOMIC other MinElute (before PCR, Qiagen) and AMPure XP (after PCR, Beckman Coulter) were used for DNA purification. Cells were lysed with CSK buffer (10 mM PIPES pH 6.8, 100 mM NaCl, 300 mM sucrose, 3 mM MgCl2, 0.1% Triton X-100). Nuclei were treated with Tn5 Transposase (Illumina). The total of 8 PCR cycles were performed to recover and amplify the DNA fragments at open chromatin. NextSeq 500 SRX15039998 GSM6071687_r1 SRP372715 PRJNA833072 SRS12786607 GSM6071687 GSM6071687 ATAC-seq GENOMIC other MinElute (before PCR, Qiagen) and AMPure XP (after PCR, Beckman Coulter) were used for DNA purification. Cells were lysed with CSK buffer (10 mM PIPES pH 6.8, 100 mM NaCl, 300 mM sucrose, 3 mM MgCl2, 0.1% Triton X-100). Nuclei were treated with Tn5 Transposase (Illumina). The total of 8 PCR cycles were performed to recover and amplify the DNA fragments at open chromatin. NextSeq 500 SRX15039999 GSM6071688_r1 SRP372715 PRJNA833072 SRS12786608 GSM6071688 GSM6071688 ATAC-seq GENOMIC other MinElute (before PCR, Qiagen) and AMPure XP (after PCR, Beckman Coulter) were used for DNA purification. Cells were lysed with CSK buffer (10 mM PIPES pH 6.8, 100 mM NaCl, 300 mM sucrose, 3 mM MgCl2, 0.1% Triton X-100). Nuclei were treated with Tn5 Transposase (Illumina). The total of 8 PCR cycles were performed to recover and amplify the DNA fragments at open chromatin. NextSeq 500 SRX15040000 GSM6071689_r1 SRP372715 PRJNA833072 SRS12786609 GSM6071689 GSM6071689 ATAC-seq GENOMIC other MinElute (before PCR, Qiagen) and AMPure XP (after PCR, Beckman Coulter) were used for DNA purification. Cells were lysed with CSK buffer (10 mM PIPES pH 6.8, 100 mM NaCl, 300 mM sucrose, 3 mM MgCl2, 0.1% Triton X-100). Nuclei were treated with Tn5 Transposase (Illumina). The total of 8 PCR cycles were performed to recover and amplify the DNA fragments at open chromatin. NextSeq 500 SRX15040001 GSM6071690_r1 SRP372715 PRJNA833072 SRS12786610 GSM6071690 GSM6071690 ATAC-seq GENOMIC other MinElute (before PCR, Qiagen) and AMPure XP (after PCR, Beckman Coulter) were used for DNA purification. Cells were lysed with CSK buffer (10 mM PIPES pH 6.8, 100 mM NaCl, 300 mM sucrose, 3 mM MgCl2, 0.1% Triton X-100). Nuclei were treated with Tn5 Transposase (Illumina). The total of 8 PCR cycles were performed to recover and amplify the DNA fragments at open chromatin. NextSeq 500 SRX15040002 GSM6071691_r1 SRP372715 PRJNA833072 SRS12786611 GSM6071691 GSM6071691 ATAC-seq GENOMIC other MinElute (before PCR, Qiagen) and AMPure XP (after PCR, Beckman Coulter) were used for DNA purification. Cells were lysed with CSK buffer (10 mM PIPES pH 6.8, 100 mM NaCl, 300 mM sucrose, 3 mM MgCl2, 0.1% Triton X-100). Nuclei were treated with Tn5 Transposase (Illumina). The total of 8 PCR cycles were performed to recover and amplify the DNA fragments at open chromatin. NextSeq 500 SRX15040003 GSM6071692_r1 SRP372715 PRJNA833072 SRS12786612 GSM6071692 GSM6071692 ATAC-seq GENOMIC other MinElute (before PCR, Qiagen) and AMPure XP (after PCR, Beckman Coulter) were used for DNA purification. Cells were lysed with CSK buffer (10 mM PIPES pH 6.8, 100 mM NaCl, 300 mM sucrose, 3 mM MgCl2, 0.1% Triton X-100). Nuclei were treated with Tn5 Transposase (Illumina). The total of 8 PCR cycles were performed to recover and amplify the DNA fragments at open chromatin. NextSeq 500 SRX15040004 GSM6071693_r1 SRP372715 PRJNA833072 SRS12786613 GSM6071693 GSM6071693 ATAC-seq GENOMIC other MinElute (before PCR, Qiagen) and AMPure XP (after PCR, Beckman Coulter) were used for DNA purification. Cells were lysed with CSK buffer (10 mM PIPES pH 6.8, 100 mM NaCl, 300 mM sucrose, 3 mM MgCl2, 0.1% Triton X-100). Nuclei were treated with Tn5 Transposase (Illumina). The total of 8 PCR cycles were performed to recover and amplify the DNA fragments at open chromatin. NextSeq 500 SRX15040005 GSM6071694_r1 SRP372715 PRJNA833072 SRS12786614 GSM6071694 GSM6071694 ATAC-seq GENOMIC other MinElute (before PCR, Qiagen) and AMPure XP (after PCR, Beckman Coulter) were used for DNA purification. Cells were lysed with CSK buffer (10 mM PIPES pH 6.8, 100 mM NaCl, 300 mM sucrose, 3 mM MgCl2, 0.1% Triton X-100). Nuclei were treated with Tn5 Transposase (Illumina). The total of 8 PCR cycles were performed to recover and amplify the DNA fragments at open chromatin. NextSeq 500 SRX15040006 GSM6071695_r1 SRP372715 PRJNA833072 SRS12786615 GSM6071695 GSM6071695 ATAC-seq GENOMIC other MinElute (before PCR, Qiagen) and AMPure XP (after PCR, Beckman Coulter) were used for DNA purification. Cells were lysed with CSK buffer (10 mM PIPES pH 6.8, 100 mM NaCl, 300 mM sucrose, 3 mM MgCl2, 0.1% Triton X-100). Nuclei were treated with Tn5 Transposase (Illumina). The total of 8 PCR cycles were performed to recover and amplify the DNA fragments at open chromatin. NextSeq 500 SRX15040007 GSM6071696_r1 SRP372715 PRJNA833072 SRS12786616 GSM6071696 GSM6071696 ATAC-seq GENOMIC other MinElute (before PCR, Qiagen) and AMPure XP (after PCR, Beckman Coulter) were used for DNA purification. Cells were lysed with CSK buffer (10 mM PIPES pH 6.8, 100 mM NaCl, 300 mM sucrose, 3 mM MgCl2, 0.1% Triton X-100). Nuclei were treated with Tn5 Transposase (Illumina). The total of 8 PCR cycles were performed to recover and amplify the DNA fragments at open chromatin. NextSeq 500 SRX15040008 GSM6071697_r1 SRP372715 PRJNA833072 SRS12786617 GSM6071697 GSM6071697 ATAC-seq GENOMIC other MinElute (before PCR, Qiagen) and AMPure XP (after PCR, Beckman Coulter) were used for DNA purification. Cells were lysed with CSK buffer (10 mM PIPES pH 6.8, 100 mM NaCl, 300 mM sucrose, 3 mM MgCl2, 0.1% Triton X-100). Nuclei were treated with Tn5 Transposase (Illumina). The total of 8 PCR cycles were performed to recover and amplify the DNA fragments at open chromatin. NextSeq 500 SRX15040009 GSM6071698_r1 SRP372715 PRJNA833072 SRS12786618 GSM6071698 GSM6071698 ATAC-seq GENOMIC other MinElute (before PCR, Qiagen) and AMPure XP (after PCR, Beckman Coulter) were used for DNA purification. Cells were lysed with CSK buffer (10 mM PIPES pH 6.8, 100 mM NaCl, 300 mM sucrose, 3 mM MgCl2, 0.1% Triton X-100). Nuclei were treated with Tn5 Transposase (Illumina). The total of 8 PCR cycles were performed to recover and amplify the DNA fragments at open chromatin. NextSeq 500