SRP374172 PRJNA836260 GSE202470 RNA-seq analysis of SIRT6 and STAT6 regulated genes in intestinal epithelial cells (IECs) To investigate the roles of SIRT6 and IL4/IL13-STAT6 pathway in intestinal epithelium homeostasis, we generated IEC-specifc Sirt6 knockout mice and transgenic mice with IEC-specific overexpression of constitutively activated STAT6 (STAT6vt). IECs from these mice were isolated and RNA were extracted and performed RNAseq analysis. Overall design: Comparative gene expression profiling analysis of RNA-seq data for IECs from Sirt6 knockout/LoxP mice and IECs from STAT6vt transgenic/WT mice GSE202470 pubmed 36057627