SRX15220731 GSM6125600_r1 SRP374506 PRJNA836767 SRS12955394 GSM6125600 GSM6125600 Bisulfite-Seq GENOMIC RANDOM gDNA was extracted using Qiagen Dneasy Blood and Tissue kit. gDNA was fragmented using the LE220 Focused ultrasonicator (Covaris) and size selected for 100-200 bp fragments using BluePippin 2% agarose cassette (Sage Sciences). End repair and A-tailing using Kapa hyper prep kit and methylated Truseq nano adapters. Bisulfite conversion was done using Zymo EZ DNA Methylation-Gold kit Illumina NovaSeq 6000 SRX15220732 GSM6125601_r1 SRP374506 PRJNA836767 SRS12955395 GSM6125601 GSM6125601 Bisulfite-Seq GENOMIC RANDOM gDNA was extracted using Qiagen Dneasy Blood and Tissue kit. gDNA was fragmented using the LE220 Focused ultrasonicator (Covaris) and size selected for 100-200 bp fragments using BluePippin 2% agarose cassette (Sage Sciences). End repair and A-tailing using Kapa hyper prep kit and methylated Truseq nano adapters. Bisulfite conversion was done using Zymo EZ DNA Methylation-Gold kit Illumina NovaSeq 6000 SRX15220733 GSM6125602_r1 SRP374506 PRJNA836767 SRS12955396 GSM6125602 GSM6125602 Bisulfite-Seq GENOMIC RANDOM gDNA was extracted using Qiagen Dneasy Blood and Tissue kit. gDNA was fragmented using the LE220 Focused ultrasonicator (Covaris) and size selected for 100-200 bp fragments using BluePippin 2% agarose cassette (Sage Sciences). End repair and A-tailing using Kapa hyper prep kit and methylated Truseq nano adapters. Bisulfite conversion was done using Zymo EZ DNA Methylation-Gold kit Illumina NovaSeq 6000 SRX15220734 GSM6125603_r1 SRP374506 PRJNA836767 SRS12955397 GSM6125603 GSM6125603 Bisulfite-Seq GENOMIC RANDOM gDNA was extracted using Qiagen Dneasy Blood and Tissue kit. gDNA was fragmented using the LE220 Focused ultrasonicator (Covaris) and size selected for 100-200 bp fragments using BluePippin 2% agarose cassette (Sage Sciences). End repair and A-tailing using Kapa hyper prep kit and methylated Truseq nano adapters. Bisulfite conversion was done using Zymo EZ DNA Methylation-Gold kit Illumina NovaSeq 6000 SRX15220735 GSM6125604_r1 SRP374506 PRJNA836767 SRS12955398 GSM6125604 GSM6125604 Bisulfite-Seq GENOMIC RANDOM gDNA was extracted using Qiagen Dneasy Blood and Tissue kit. gDNA was fragmented using the LE220 Focused ultrasonicator (Covaris) and size selected for 100-200 bp fragments using BluePippin 2% agarose cassette (Sage Sciences). End repair and A-tailing using Kapa hyper prep kit and methylated Truseq nano adapters. Bisulfite conversion was done using Zymo EZ DNA Methylation-Gold kit Illumina NovaSeq 6000 SRX15220736 GSM6125605_r1 SRP374506 PRJNA836767 SRS12955399 GSM6125605 GSM6125605 Bisulfite-Seq GENOMIC RANDOM gDNA was extracted using Qiagen Dneasy Blood and Tissue kit. gDNA was fragmented using the LE220 Focused ultrasonicator (Covaris) and size selected for 100-200 bp fragments using BluePippin 2% agarose cassette (Sage Sciences). End repair and A-tailing using Kapa hyper prep kit and methylated Truseq nano adapters. Bisulfite conversion was done using Zymo EZ DNA Methylation-Gold kit Illumina NovaSeq 6000