<?xml version="1.0" encoding="UTF-8"?>
<STUDY_SET xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <STUDY center_name="GEO" alias="GSE202691" accession="SRP374608">
    <IDENTIFIERS>
      <PRIMARY_ID>SRP374608</PRIMARY_ID>
      <EXTERNAL_ID namespace="BioProject" label="primary">PRJNA836955</EXTERNAL_ID>
      <EXTERNAL_ID namespace="GEO">GSE202691</EXTERNAL_ID>
    </IDENTIFIERS>
    <DESCRIPTOR>
      <STUDY_TITLE>Single cell gene expression analysis of mouse colon ?CRd+CD8a+ and TCRß+CD8a+ intraepitehlial lymphocytes (IELs)</STUDY_TITLE>
      <STUDY_TYPE existing_study_type="Transcriptome Analysis"/>
      <STUDY_ABSTRACT>TCF-1 is highly expressed in colon T- IELs.T? understand the role of TCF-1 in regulating the gene expression of colon CD8+ T IELs, we isolated and sorted CD8a+TCRd+ and CD8a+TCRß+ from colons of  E8?cre-Transgentic Tcf7 floxed mice or control Tcf7 floxed mice. Overall design: Single cell RNA sequencing of  colon ?CR?d+CD8a+ and TCRß+CD8a+ IELs from mice with and without Tcf7 (E8ICre, Tcf7 floxed)</STUDY_ABSTRACT>
      <CENTER_PROJECT_NAME>GSE202691</CENTER_PROJECT_NAME>
    </DESCRIPTOR>
    <STUDY_LINKS>
      <STUDY_LINK>
        <XREF_LINK>
          <DB>pubmed</DB>
          <ID>37801516</ID>
        </XREF_LINK>
      </STUDY_LINK>
    </STUDY_LINKS>
    <STUDY_ATTRIBUTES>
      <STUDY_ATTRIBUTE>
        <TAG>parent_bioproject</TAG>
        <VALUE>PRJNA836954</VALUE>
      </STUDY_ATTRIBUTE>
    </STUDY_ATTRIBUTES>
  </STUDY>
</STUDY_SET>
