<?xml version="1.0" encoding="UTF-8"?>
<STUDY_SET xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <STUDY center_name="GEO" alias="GSE216542" accession="SRP404481">
    <IDENTIFIERS>
      <PRIMARY_ID>SRP404481</PRIMARY_ID>
      <EXTERNAL_ID namespace="BioProject" label="primary">PRJNA894189</EXTERNAL_ID>
      <EXTERNAL_ID namespace="GEO">GSE216542</EXTERNAL_ID>
    </IDENTIFIERS>
    <DESCRIPTOR>
      <STUDY_TITLE>scRNA-seq, snATAC-seq, and spatial transcriptomics analysis of mammary glands of aged female mice</STUDY_TITLE>
      <STUDY_TYPE existing_study_type="Other"/>
      <STUDY_ABSTRACT>Aging results in changes in mammary gland cell proportions, gene expression, and chromatin accessibility. Cell types captured include epithelial, immune, and stromal cell types. Overall design: Mammary gland 3M and 18M old virgin female C57BL/6J mice were enzymatically and mechanically digested. Single cells were FACS-sorted based on viability prior to performing scRNA-seq (10X Chromium v.3 chemistry) and snATAC-seq (10X Chromium v.1)</STUDY_ABSTRACT>
      <CENTER_PROJECT_NAME>GSE216542</CENTER_PROJECT_NAME>
    </DESCRIPTOR>
    <STUDY_LINKS>
      <STUDY_LINK>
        <XREF_LINK>
          <DB>pubmed</DB>
          <ID>39587369</ID>
        </XREF_LINK>
      </STUDY_LINK>
    </STUDY_LINKS>
  </STUDY>
</STUDY_SET>
