SRP404702 PRJNA894544 Antibiotic Resistance of Enterobacteriaceae in Athens (AREA) This project was a large-scale human study of stool carriage of antibiotic resistant Enterobacteriaceae, with a particular focus on extended spectrum beta lactamase-producing Enterobacteriaceae. Participants were recruited from the Athens, GA, USA area. Inclusion criteria for enrollment included adults age 18 and up, as well as a sub-cohort of minor children (age 5 and younger) of enrolled parents. Exclusion criteria included hospitalization or overnight care in a healthcare setting within the last year, pregnancy at time of sample collection, or use of antibiotics within 48 hours of sample collection. Enrollees were provided kits and instructions for self-collection of stool samples, and were asked to store collected samples in a fridge or cooler and return them within 24 hours of collection. Samples were processed (aliquoted and frozen and/or used for initial culture efforts) within 36 hours of their return to the study center. Sample types associated with this project include genome sequences of cultured Enterobacteriaceae and metagenomic data including 16S rRNA gene sequence libraries, shotgun metagenomic libraries, and shotgun metagenomic libraries that were enriched for antibiotic resistance genes.