SRX18352941 GSM6752839_r1 SRP409288 PRJNA904357 SRS15840451 GSM6752839 GSM6752839 ChIP-Seq GENOMIC ChIP Materials of HZ62 were collected and cross-linked using 1% formaldehyde (Sigma, F8775) and quenched with 0.2M glycine (Sigma, G7126) at room temperature. About 1g of samples were used for each library. After grinding into fine powder with liquid nitrogen, cell lysis by 1% SDS (Sigma, AM9822) at 4°C. The chromatin was fragment by sonication using a Bioruptor (Diagenode) into 200-600 bp. ChIP was performed using H3K4me3 and H3K27me3 antibody (Abclonal, A2357, A2363). Then, the protein-DNA complexes were reversed cross-linking using proteinase K (Invitrogen, AM2546) at 55°C. ChIP-DNA was extracted using phenol:chloroform:isoamyl alcohol (Sigma, P3803). ChIP-DNA libraries were constructed by using NEBNext Ultra II DNA library prep kit for Illumina (New England BioLabs, E7645) according to the manufacturer's guidelines. HiSeq X Ten SRX18352942 GSM6752840_r1 SRP409288 PRJNA904357 SRS15840450 GSM6752840 GSM6752840 ChIP-Seq GENOMIC ChIP Materials of HZ62 were collected and cross-linked using 1% formaldehyde (Sigma, F8775) and quenched with 0.2M glycine (Sigma, G7126) at room temperature. About 1g of samples were used for each library. After grinding into fine powder with liquid nitrogen, cell lysis by 1% SDS (Sigma, AM9822) at 4°C. The chromatin was fragment by sonication using a Bioruptor (Diagenode) into 200-600 bp. ChIP was performed using H3K4me3 and H3K27me3 antibody (Abclonal, A2357, A2363). Then, the protein-DNA complexes were reversed cross-linking using proteinase K (Invitrogen, AM2546) at 55°C. ChIP-DNA was extracted using phenol:chloroform:isoamyl alcohol (Sigma, P3803). ChIP-DNA libraries were constructed by using NEBNext Ultra II DNA library prep kit for Illumina (New England BioLabs, E7645) according to the manufacturer's guidelines. HiSeq X Ten SRX18352943 GSM6752841_r1 SRP409288 PRJNA904357 SRS15840453 GSM6752841 GSM6752841 ChIP-Seq GENOMIC ChIP Materials of HZ62 were collected and cross-linked using 1% formaldehyde (Sigma, F8775) and quenched with 0.2M glycine (Sigma, G7126) at room temperature. About 1g of samples were used for each library. After grinding into fine powder with liquid nitrogen, cell lysis by 1% SDS (Sigma, AM9822) at 4°C. The chromatin was fragment by sonication using a Bioruptor (Diagenode) into 200-600 bp. ChIP was performed using H3K4me3 and H3K27me3 antibody (Abclonal, A2357, A2363). Then, the protein-DNA complexes were reversed cross-linking using proteinase K (Invitrogen, AM2546) at 55°C. ChIP-DNA was extracted using phenol:chloroform:isoamyl alcohol (Sigma, P3803). ChIP-DNA libraries were constructed by using NEBNext Ultra II DNA library prep kit for Illumina (New England BioLabs, E7645) according to the manufacturer's guidelines. HiSeq X Ten SRX18352944 GSM6752842_r1 SRP409288 PRJNA904357 SRS15840452 GSM6752842 GSM6752842 ChIP-Seq GENOMIC ChIP Materials of HZ62 were collected and cross-linked using 1% formaldehyde (Sigma, F8775) and quenched with 0.2M glycine (Sigma, G7126) at room temperature. About 1g of samples were used for each library. After grinding into fine powder with liquid nitrogen, cell lysis by 1% SDS (Sigma, AM9822) at 4°C. The chromatin was fragment by sonication using a Bioruptor (Diagenode) into 200-600 bp. ChIP was performed using H3K4me3 and H3K27me3 antibody (Abclonal, A2357, A2363). Then, the protein-DNA complexes were reversed cross-linking using proteinase K (Invitrogen, AM2546) at 55°C. ChIP-DNA was extracted using phenol:chloroform:isoamyl alcohol (Sigma, P3803). ChIP-DNA libraries were constructed by using NEBNext Ultra II DNA library prep kit for Illumina (New England BioLabs, E7645) according to the manufacturer's guidelines. HiSeq X Ten SRX18352945 GSM6752843_r1 SRP409288 PRJNA904357 SRS15840455 GSM6752843 GSM6752843 ChIP-Seq GENOMIC ChIP Materials of HZ62 were collected and cross-linked using 1% formaldehyde (Sigma, F8775) and quenched with 0.2M glycine (Sigma, G7126) at room temperature. About 1g of samples were used for each library. After grinding into fine powder with liquid nitrogen, cell lysis by 1% SDS (Sigma, AM9822) at 4°C. The chromatin was fragment by sonication using a Bioruptor (Diagenode) into 200-600 bp. ChIP was performed using H3K4me3 and H3K27me3 antibody (Abclonal, A2357, A2363). Then, the protein-DNA complexes were reversed cross-linking using proteinase K (Invitrogen, AM2546) at 55°C. ChIP-DNA was extracted using phenol:chloroform:isoamyl alcohol (Sigma, P3803). ChIP-DNA libraries were constructed by using NEBNext Ultra II DNA library prep kit for Illumina (New England BioLabs, E7645) according to the manufacturer's guidelines. HiSeq X Ten SRX18352946 GSM6752844_r1 SRP409288 PRJNA904357 SRS15840454 GSM6752844 GSM6752844 ChIP-Seq GENOMIC ChIP Materials of HZ62 were collected and cross-linked using 1% formaldehyde (Sigma, F8775) and quenched with 0.2M glycine (Sigma, G7126) at room temperature. About 1g of samples were used for each library. After grinding into fine powder with liquid nitrogen, cell lysis by 1% SDS (Sigma, AM9822) at 4°C. The chromatin was fragment by sonication using a Bioruptor (Diagenode) into 200-600 bp. ChIP was performed using H3K4me3 and H3K27me3 antibody (Abclonal, A2357, A2363). Then, the protein-DNA complexes were reversed cross-linking using proteinase K (Invitrogen, AM2546) at 55°C. ChIP-DNA was extracted using phenol:chloroform:isoamyl alcohol (Sigma, P3803). ChIP-DNA libraries were constructed by using NEBNext Ultra II DNA library prep kit for Illumina (New England BioLabs, E7645) according to the manufacturer's guidelines. HiSeq X Ten SRX18352947 GSM6752845_r1 SRP409288 PRJNA904357 SRS15840456 GSM6752845 GSM6752845 ChIP-Seq GENOMIC ChIP Materials of HZ62 were collected and cross-linked using 1% formaldehyde (Sigma, F8775) and quenched with 0.2M glycine (Sigma, G7126) at room temperature. About 1g of samples were used for each library. After grinding into fine powder with liquid nitrogen, cell lysis by 1% SDS (Sigma, AM9822) at 4°C. The chromatin was fragment by sonication using a Bioruptor (Diagenode) into 200-600 bp. ChIP was performed using H3K4me3 and H3K27me3 antibody (Abclonal, A2357, A2363). Then, the protein-DNA complexes were reversed cross-linking using proteinase K (Invitrogen, AM2546) at 55°C. ChIP-DNA was extracted using phenol:chloroform:isoamyl alcohol (Sigma, P3803). ChIP-DNA libraries were constructed by using NEBNext Ultra II DNA library prep kit for Illumina (New England BioLabs, E7645) according to the manufacturer's guidelines. HiSeq X Ten SRX18352948 GSM6752846_r1 SRP409288 PRJNA904357 SRS15840457 GSM6752846 GSM6752846 ChIP-Seq GENOMIC ChIP Materials of HZ62 were collected and cross-linked using 1% formaldehyde (Sigma, F8775) and quenched with 0.2M glycine (Sigma, G7126) at room temperature. About 1g of samples were used for each library. After grinding into fine powder with liquid nitrogen, cell lysis by 1% SDS (Sigma, AM9822) at 4°C. The chromatin was fragment by sonication using a Bioruptor (Diagenode) into 200-600 bp. ChIP was performed using H3K4me3 and H3K27me3 antibody (Abclonal, A2357, A2363). Then, the protein-DNA complexes were reversed cross-linking using proteinase K (Invitrogen, AM2546) at 55°C. ChIP-DNA was extracted using phenol:chloroform:isoamyl alcohol (Sigma, P3803). ChIP-DNA libraries were constructed by using NEBNext Ultra II DNA library prep kit for Illumina (New England BioLabs, E7645) according to the manufacturer's guidelines. HiSeq X Ten SRX18352949 GSM6752847_r1 SRP409288 PRJNA904357 SRS15840458 GSM6752847 GSM6752847 ChIP-Seq GENOMIC ChIP Materials of HZ62 were collected and cross-linked using 1% formaldehyde (Sigma, F8775) and quenched with 0.2M glycine (Sigma, G7126) at room temperature. About 1g of samples were used for each library. After grinding into fine powder with liquid nitrogen, cell lysis by 1% SDS (Sigma, AM9822) at 4°C. The chromatin was fragment by sonication using a Bioruptor (Diagenode) into 200-600 bp. ChIP was performed using H3K4me3 and H3K27me3 antibody (Abclonal, A2357, A2363). Then, the protein-DNA complexes were reversed cross-linking using proteinase K (Invitrogen, AM2546) at 55°C. ChIP-DNA was extracted using phenol:chloroform:isoamyl alcohol (Sigma, P3803). ChIP-DNA libraries were constructed by using NEBNext Ultra II DNA library prep kit for Illumina (New England BioLabs, E7645) according to the manufacturer's guidelines. HiSeq X Ten SRX18352950 GSM6752848_r1 SRP409288 PRJNA904357 SRS15840459 GSM6752848 GSM6752848 ChIP-Seq GENOMIC ChIP Materials of HZ62 were collected and cross-linked using 1% formaldehyde (Sigma, F8775) and quenched with 0.2M glycine (Sigma, G7126) at room temperature. About 1g of samples were used for each library. After grinding into fine powder with liquid nitrogen, cell lysis by 1% SDS (Sigma, AM9822) at 4°C. The chromatin was fragment by sonication using a Bioruptor (Diagenode) into 200-600 bp. ChIP was performed using H3K4me3 and H3K27me3 antibody (Abclonal, A2357, A2363). Then, the protein-DNA complexes were reversed cross-linking using proteinase K (Invitrogen, AM2546) at 55°C. ChIP-DNA was extracted using phenol:chloroform:isoamyl alcohol (Sigma, P3803). ChIP-DNA libraries were constructed by using NEBNext Ultra II DNA library prep kit for Illumina (New England BioLabs, E7645) according to the manufacturer's guidelines. HiSeq X Ten SRX18352951 GSM6752849_r1 SRP409288 PRJNA904357 SRS15840460 GSM6752849 GSM6752849 ChIP-Seq GENOMIC ChIP Materials of HZ62 were collected and cross-linked using 1% formaldehyde (Sigma, F8775) and quenched with 0.2M glycine (Sigma, G7126) at room temperature. About 1g of samples were used for each library. After grinding into fine powder with liquid nitrogen, cell lysis by 1% SDS (Sigma, AM9822) at 4°C. The chromatin was fragment by sonication using a Bioruptor (Diagenode) into 200-600 bp. ChIP was performed using H3K4me3 and H3K27me3 antibody (Abclonal, A2357, A2363). Then, the protein-DNA complexes were reversed cross-linking using proteinase K (Invitrogen, AM2546) at 55°C. ChIP-DNA was extracted using phenol:chloroform:isoamyl alcohol (Sigma, P3803). ChIP-DNA libraries were constructed by using NEBNext Ultra II DNA library prep kit for Illumina (New England BioLabs, E7645) according to the manufacturer's guidelines. HiSeq X Ten SRX18352952 GSM6752850_r1 SRP409288 PRJNA904357 SRS15840461 GSM6752850 GSM6752850 ChIP-Seq GENOMIC ChIP Materials of HZ62 were collected and cross-linked using 1% formaldehyde (Sigma, F8775) and quenched with 0.2M glycine (Sigma, G7126) at room temperature. About 1g of samples were used for each library. After grinding into fine powder with liquid nitrogen, cell lysis by 1% SDS (Sigma, AM9822) at 4°C. The chromatin was fragment by sonication using a Bioruptor (Diagenode) into 200-600 bp. ChIP was performed using H3K4me3 and H3K27me3 antibody (Abclonal, A2357, A2363). Then, the protein-DNA complexes were reversed cross-linking using proteinase K (Invitrogen, AM2546) at 55°C. ChIP-DNA was extracted using phenol:chloroform:isoamyl alcohol (Sigma, P3803). ChIP-DNA libraries were constructed by using NEBNext Ultra II DNA library prep kit for Illumina (New England BioLabs, E7645) according to the manufacturer's guidelines. HiSeq X Ten