SRP409385 PRJNA904655 GSE218609 Dynamics of m6A RNA methylome during leukemogenesis reveals a role of PRMT6-MFSD2A signaling axis in maintaining AML stem cells.[Chip-seq] We delineate a comprehensive m6A landscape during acute myeloid leukemia (AML) development, and identify PRMT6, regulated by IGF2BP2, acting as a key for leukemia stem cell maintenance by restraining MFSD2A expression and docosahexaenoic acid level. Overall design: H3R2me2a ChIP-seq of Prmt6-/- and Igf2bp2-/- leukemia cells GSE218609 pubmed 36574771 parent_bioproject PRJNA904647