SRX18385149 GSM6757104_r1 SRP409976 PRJNA905693 SRS15870763 GSM6757104 GSM6757104 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385150 GSM6757105_r1 SRP409976 PRJNA905693 SRS15870764 GSM6757105 GSM6757105 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385151 GSM6757106_r1 SRP409976 PRJNA905693 SRS15870765 GSM6757106 GSM6757106 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385152 GSM6757107_r1 SRP409976 PRJNA905693 SRS15870766 GSM6757107 GSM6757107 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385153 GSM6757108_r1 SRP409976 PRJNA905693 SRS15870767 GSM6757108 GSM6757108 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385154 GSM6757109_r1 SRP409976 PRJNA905693 SRS15870768 GSM6757109 GSM6757109 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385155 GSM6757110_r1 SRP409976 PRJNA905693 SRS15870769 GSM6757110 GSM6757110 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385156 GSM6757111_r1 SRP409976 PRJNA905693 SRS15870770 GSM6757111 GSM6757111 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385157 GSM6757112_r1 SRP409976 PRJNA905693 SRS15870771 GSM6757112 GSM6757112 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385158 GSM6757113_r1 SRP409976 PRJNA905693 SRS15870772 GSM6757113 GSM6757113 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385159 GSM6757114_r1 SRP409976 PRJNA905693 SRS15870773 GSM6757114 GSM6757114 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385160 GSM6757115_r1 SRP409976 PRJNA905693 SRS15870774 GSM6757115 GSM6757115 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385161 GSM6757116_r1 SRP409976 PRJNA905693 SRS15870775 GSM6757116 GSM6757116 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385162 GSM6757117_r1 SRP409976 PRJNA905693 SRS15870776 GSM6757117 GSM6757117 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385163 GSM6757118_r1 SRP409976 PRJNA905693 SRS15870777 GSM6757118 GSM6757118 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385164 GSM6757119_r1 SRP409976 PRJNA905693 SRS15870778 GSM6757119 GSM6757119 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385165 GSM6757120_r1 SRP409976 PRJNA905693 SRS15870779 GSM6757120 GSM6757120 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385166 GSM6757121_r1 SRP409976 PRJNA905693 SRS15870780 GSM6757121 GSM6757121 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385167 GSM6757122_r1 SRP409976 PRJNA905693 SRS15870781 GSM6757122 GSM6757122 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385168 GSM6757123_r1 SRP409976 PRJNA905693 SRS15870782 GSM6757123 GSM6757123 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385169 GSM6757124_r1 SRP409976 PRJNA905693 SRS15870783 GSM6757124 GSM6757124 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385170 GSM6757125_r1 SRP409976 PRJNA905693 SRS15870784 GSM6757125 GSM6757125 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385171 GSM6757126_r1 SRP409976 PRJNA905693 SRS15870785 GSM6757126 GSM6757126 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385172 GSM6757127_r1 SRP409976 PRJNA905693 SRS15870786 GSM6757127 GSM6757127 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385173 GSM6757128_r1 SRP409976 PRJNA905693 SRS15870787 GSM6757128 GSM6757128 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385174 GSM6757129_r1 SRP409976 PRJNA905693 SRS15870788 GSM6757129 GSM6757129 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385175 GSM6757130_r1 SRP409976 PRJNA905693 SRS15870789 GSM6757130 GSM6757130 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385176 GSM6757131_r1 SRP409976 PRJNA905693 SRS15870790 GSM6757131 GSM6757131 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385177 GSM6757132_r1 SRP409976 PRJNA905693 SRS15870791 GSM6757132 GSM6757132 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385178 GSM6757133_r1 SRP409976 PRJNA905693 SRS15870792 GSM6757133 GSM6757133 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385179 GSM6757134_r1 SRP409976 PRJNA905693 SRS15870793 GSM6757134 GSM6757134 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385180 GSM6757135_r1 SRP409976 PRJNA905693 SRS15870794 GSM6757135 GSM6757135 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385181 GSM6757136_r1 SRP409976 PRJNA905693 SRS15870795 GSM6757136 GSM6757136 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385182 GSM6757137_r1 SRP409976 PRJNA905693 SRS15870796 GSM6757137 GSM6757137 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385183 GSM6757138_r1 SRP409976 PRJNA905693 SRS15870797 GSM6757138 GSM6757138 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385184 GSM6757139_r1 SRP409976 PRJNA905693 SRS15870798 GSM6757139 GSM6757139 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385185 GSM6757140_r1 SRP409976 PRJNA905693 SRS15870799 GSM6757140 GSM6757140 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385186 GSM6757141_r1 SRP409976 PRJNA905693 SRS15870800 GSM6757141 GSM6757141 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385187 GSM6757142_r1 SRP409976 PRJNA905693 SRS15870801 GSM6757142 GSM6757142 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385188 GSM6757143_r1 SRP409976 PRJNA905693 SRS15870802 GSM6757143 GSM6757143 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385189 GSM6757144_r1 SRP409976 PRJNA905693 SRS15870803 GSM6757144 GSM6757144 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385190 GSM6757145_r1 SRP409976 PRJNA905693 SRS15870804 GSM6757145 GSM6757145 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385191 GSM6757146_r1 SRP409976 PRJNA905693 SRS15870805 GSM6757146 GSM6757146 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385192 GSM6757147_r1 SRP409976 PRJNA905693 SRS15870806 GSM6757147 GSM6757147 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385193 GSM6757148_r1 SRP409976 PRJNA905693 SRS15870807 GSM6757148 GSM6757148 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385194 GSM6757149_r1 SRP409976 PRJNA905693 SRS15870808 GSM6757149 GSM6757149 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385195 GSM6757150_r1 SRP409976 PRJNA905693 SRS15870809 GSM6757150 GSM6757150 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385196 GSM6757151_r1 SRP409976 PRJNA905693 SRS15870810 GSM6757151 GSM6757151 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385197 GSM6757168_r1 SRP409976 PRJNA905693 SRS15870811 GSM6757168 GSM6757168 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385198 GSM6757169_r1 SRP409976 PRJNA905693 SRS15870812 GSM6757169 GSM6757169 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385199 GSM6757170_r1 SRP409976 PRJNA905693 SRS15870813 GSM6757170 GSM6757170 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385200 GSM6757171_r1 SRP409976 PRJNA905693 SRS15870814 GSM6757171 GSM6757171 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385201 GSM6757172_r1 SRP409976 PRJNA905693 SRS15870815 GSM6757172 GSM6757172 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385202 GSM6757173_r1 SRP409976 PRJNA905693 SRS15870816 GSM6757173 GSM6757173 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385203 GSM6757174_r1 SRP409976 PRJNA905693 SRS15870817 GSM6757174 GSM6757174 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385204 GSM6757175_r1 SRP409976 PRJNA905693 SRS15870818 GSM6757175 GSM6757175 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385205 GSM6757176_r1 SRP409976 PRJNA905693 SRS15870819 GSM6757176 GSM6757176 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385206 GSM6757177_r1 SRP409976 PRJNA905693 SRS15870820 GSM6757177 GSM6757177 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385207 GSM6757178_r1 SRP409976 PRJNA905693 SRS15870821 GSM6757178 GSM6757178 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385208 GSM6757179_r1 SRP409976 PRJNA905693 SRS15870822 GSM6757179 GSM6757179 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385209 GSM6757180_r1 SRP409976 PRJNA905693 SRS15870823 GSM6757180 GSM6757180 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385210 GSM6757181_r1 SRP409976 PRJNA905693 SRS15870824 GSM6757181 GSM6757181 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385211 GSM6757182_r1 SRP409976 PRJNA905693 SRS15870825 GSM6757182 GSM6757182 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385212 GSM6757183_r1 SRP409976 PRJNA905693 SRS15870826 GSM6757183 GSM6757183 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385213 GSM6757152_r1 SRP409976 PRJNA905693 SRS15870827 GSM6757152 GSM6757152 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385214 GSM6757153_r1 SRP409976 PRJNA905693 SRS15870828 GSM6757153 GSM6757153 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385215 GSM6757154_r1 SRP409976 PRJNA905693 SRS15870829 GSM6757154 GSM6757154 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385216 GSM6757155_r1 SRP409976 PRJNA905693 SRS15870830 GSM6757155 GSM6757155 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385217 GSM6757156_r1 SRP409976 PRJNA905693 SRS15870831 GSM6757156 GSM6757156 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385218 GSM6757157_r1 SRP409976 PRJNA905693 SRS15870832 GSM6757157 GSM6757157 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385219 GSM6757158_r1 SRP409976 PRJNA905693 SRS15870833 GSM6757158 GSM6757158 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385220 GSM6757159_r1 SRP409976 PRJNA905693 SRS15870834 GSM6757159 GSM6757159 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385221 GSM6757160_r1 SRP409976 PRJNA905693 SRS15870835 GSM6757160 GSM6757160 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385222 GSM6757161_r1 SRP409976 PRJNA905693 SRS15870836 GSM6757161 GSM6757161 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385223 GSM6757162_r1 SRP409976 PRJNA905693 SRS15870837 GSM6757162 GSM6757162 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385224 GSM6757163_r1 SRP409976 PRJNA905693 SRS15870838 GSM6757163 GSM6757163 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385225 GSM6757164_r1 SRP409976 PRJNA905693 SRS15870839 GSM6757164 GSM6757164 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385226 GSM6757165_r1 SRP409976 PRJNA905693 SRS15870840 GSM6757165 GSM6757165 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385227 GSM6757166_r1 SRP409976 PRJNA905693 SRS15870841 GSM6757166 GSM6757166 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385228 GSM6757167_r1 SRP409976 PRJNA905693 SRS15870842 GSM6757167 GSM6757167 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500 SRX18385229 GSM6757184_r1 SRP409976 PRJNA905693 SRS15870843 GSM6757184 GSM6757184 miRNA-Seq TRANSCRIPTOMIC size fractionation Stool RNA was extracted from 200µl aliquots using stool total RNA purification kit (Norgen Biotek Corp.) following manufacturer's protocol. RNA quality and quantity were verified following the MIQE guidelines (http://miqe.gene-quantification.info/). The RNA concentration was quantified with the Qubit microRNA assay kit (Invitrogen). The DNA was extracted with the DNeasy PowerSoil Pro Kit (Qiagen) following manufacturer's instructions with a higher final elution buffer volume (50µl) to increase DNA concentration which was quantified with Qubit DNA high sensitivity assay kit (Invitrogen). Small RNA (sRNA) transcripts were converted into barcoded cDNA libraries. Library preparation was performed with the NEBNext Multiplex Small RNA Library Prep Set for Illumina (Protocol E7330, New England BioLabs Inc., USA). NextSeq 500