<?xml version="1.0" encoding="UTF-8"?>
<STUDY_SET xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <STUDY center_name="GEO" alias="GSE220196" accession="SRP411633">
    <IDENTIFIERS>
      <PRIMARY_ID>SRP411633</PRIMARY_ID>
      <EXTERNAL_ID namespace="BioProject" label="primary">PRJNA909221</EXTERNAL_ID>
      <EXTERNAL_ID namespace="GEO">GSE220196</EXTERNAL_ID>
    </IDENTIFIERS>
    <DESCRIPTOR>
      <STUDY_TITLE>Ac4c modifications down-regulation in macrophages promotes suppressive tumor microenvironment in HCC</STUDY_TITLE>
      <STUDY_TYPE existing_study_type="Transcriptome Analysis"/>
      <STUDY_ABSTRACT>To investigated how NAT10 inhibitor (Remodelin hydrobromide) affected the function of peritoneal macrophages , we treated peritoneal macrophages  IFN y,Remodelin hydrobromide and Remodelin hydrobromide with IFN y. We then performed gene expression profiling analysis using data obtained from RNA-seq of peritoneal macrophages with four treaments Overall design: Comparative gene expression profiling analysis of RNA-seq data for treated with IFNy,Remodelin hydrobromide and Remodelin hydrobromide with IFNy.</STUDY_ABSTRACT>
      <CENTER_PROJECT_NAME>GSE220196</CENTER_PROJECT_NAME>
    </DESCRIPTOR>
    <STUDY_LINKS>
      <STUDY_LINK>
        <XREF_LINK>
          <DB>pubmed</DB>
          <ID>38040817</ID>
        </XREF_LINK>
      </STUDY_LINK>
    </STUDY_LINKS>
  </STUDY>
</STUDY_SET>
