<?xml version="1.0" encoding="UTF-8"?>
<STUDY_SET xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <STUDY center_name="BioProject" alias="PRJNA971347" accession="SRP437310">
    <IDENTIFIERS>
      <PRIMARY_ID>SRP437310</PRIMARY_ID>
      <EXTERNAL_ID namespace="BioProject" label="primary">PRJNA971347</EXTERNAL_ID>
    </IDENTIFIERS>
    <DESCRIPTOR>
      <STUDY_TITLE>Virulence Genes of Four Extended Spectrum Beta-Lactamase Producing Acinetobacter baumannii from Orthopedic Patients and Environment of a Tertiary Referral Hospital in  Mwanza, Tanzania</STUDY_TITLE>
      <STUDY_TYPE existing_study_type="Whole Genome Sequencing"/>
      <STUDY_ABSTRACT>Acinetobacter baumannii has emerged as an important nosocomial pathogen due to its high resistance to multi-drugs and disinfectants plus its ability to survive in the hospital environment that is detrimental to most pathogens. Understanding the arsenals of virulence genes among extended-spectrum Beta-lactamase (ESBL)-producing-Acinetobacter baumannii isolates from patients and hospital environment is crucial for surveillance and informing strategies for control and prevention of this deadly nosocomial pathogen. We used whole-genome sequencing (WGS) to unravel the sequence types (ST), ESBL-alleles, and virulence genes of ESBLs-producing Acinetobacter baumannii isolated from orthopedic patients and hospital environments of Bugando Medical Centre, a tertiary referral hospital in Mwanza, Tanzania</STUDY_ABSTRACT>
      <CENTER_PROJECT_NAME>Acinetobacter baumannii isolate:Acinetobacter baumannii | breed:missing data | cultivar:missing data</CENTER_PROJECT_NAME>
    </DESCRIPTOR>
    <STUDY_LINKS>
      <STUDY_LINK>
        <XREF_LINK>
          <DB>pubmed</DB>
          <ID>37729952</ID>
        </XREF_LINK>
      </STUDY_LINK>
      <STUDY_LINK>
        <URL_LINK>
          <LABEL>Understanding Transmission Dynamics and Acquisition of Antimicrobial Resistance at Referral Hospitals and Community Settings in East Africa</LABEL>
          <URL>https://gcgh.grandchallenges.org/grant/understanding-transmission-dynamics-and-acquisition-antimicrobial-resistance-referral</URL>
        </URL_LINK>
      </STUDY_LINK>
    </STUDY_LINKS>
  </STUDY>
</STUDY_SET>
