SRX621390 GSM1419173 SRP043528 SRS645360 GSM1419173 miRNA-Seq TRANSCRIPTOMIC size fractionation Cecum was removed, flash frozen on dry ice, and RNA was harvested using Trizol reagent The smaller RNA fraction (<100KDa) was further fractioned on a 15% tris-borate-EDTA (TBE) urea polyacrylamide gel and the 18-38 nt fraction was obtained. Subsequently, 5′ and 3′ RNA adapters were ligated to the small RNA by T4 RNA ligase (Promega), followed by reverse transcription and PCR product purification. Purified products were quantified on the Qubit® 2.0 fluorometer (Invitrogen) using QubitTM dsDNA HS array kit(Invitrogen), then were diluted to 2 nM to finish cluster generation Illumina Genome Analyzer IIx GEO Sample GSM1419173 http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSM1419173 gds 301419173 GEO Accession GSM1419173 SRX621391 GSM1419174 SRP043528 SRS645361 GSM1419174 miRNA-Seq TRANSCRIPTOMIC size fractionation Cecum was removed, flash frozen on dry ice, and RNA was harvested using Trizol reagent The smaller RNA fraction (<100KDa) was further fractioned on a 15% tris-borate-EDTA (TBE) urea polyacrylamide gel and the 18-38 nt fraction was obtained. Subsequently, 5′ and 3′ RNA adapters were ligated to the small RNA by T4 RNA ligase (Promega), followed by reverse transcription and PCR product purification. Purified products were quantified on the Qubit® 2.0 fluorometer (Invitrogen) using QubitTM dsDNA HS array kit(Invitrogen), then were diluted to 2 nM to finish cluster generation Illumina Genome Analyzer IIx GEO Sample GSM1419174 http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSM1419174 gds 301419174 GEO Accession GSM1419174 SRX621392 GSM1419175 SRP043528 SRS645362 GSM1419175 miRNA-Seq TRANSCRIPTOMIC size fractionation Cecum was removed, flash frozen on dry ice, and RNA was harvested using Trizol reagent The smaller RNA fraction (<100KDa) was further fractioned on a 15% tris-borate-EDTA (TBE) urea polyacrylamide gel and the 18-38 nt fraction was obtained. Subsequently, 5′ and 3′ RNA adapters were ligated to the small RNA by T4 RNA ligase (Promega), followed by reverse transcription and PCR product purification. Purified products were quantified on the Qubit® 2.0 fluorometer (Invitrogen) using QubitTM dsDNA HS array kit(Invitrogen), then were diluted to 2 nM to finish cluster generation Illumina Genome Analyzer IIx GEO Sample GSM1419175 http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSM1419175 gds 301419175 GEO Accession GSM1419175 SRX621393 GSM1419176 SRP043528 SRS645363 GSM1419176 miRNA-Seq TRANSCRIPTOMIC size fractionation Cecum was removed, flash frozen on dry ice, and RNA was harvested using Trizol reagent The smaller RNA fraction (<100KDa) was further fractioned on a 15% tris-borate-EDTA (TBE) urea polyacrylamide gel and the 18-38 nt fraction was obtained. Subsequently, 5′ and 3′ RNA adapters were ligated to the small RNA by T4 RNA ligase (Promega), followed by reverse transcription and PCR product purification. Purified products were quantified on the Qubit® 2.0 fluorometer (Invitrogen) using QubitTM dsDNA HS array kit(Invitrogen), then were diluted to 2 nM to finish cluster generation Illumina Genome Analyzer IIx GEO Sample GSM1419176 http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSM1419176 gds 301419176 GEO Accession GSM1419176