SRX22297304 N1_Landrace SRP469395 bp0 Hearts were removed, placed in Krebs bicarbonate buffer (0-4 C) and weighed. Then EAT was collected from occluded and non-occluded regions of the left circumflex coronary artery. To isolate RNA from adipose tissue, ~ 0.1 grams of snap-frozen EAT was used. The samples were then subjected to Bulk RNAseq and single Nucleus RNAseq followed by bioinformatic analysis. SRS19348038 N1_Landrace N1_Landrace RNA-Seq TRANSCRIPTOMIC SINGLE CELL cDNA Illumina NovaSeq 6000 SRX22297305 N2_Landrace SRP469395 bp0 Hearts were removed, placed in Krebs bicarbonate buffer (0-4 C) and weighed. Then EAT was collected from occluded and non-occluded regions of the left circumflex coronary artery. To isolate RNA from adipose tissue, ~ 0.1 grams of snap-frozen EAT was used. The samples were then subjected to Bulk RNAseq and single Nucleus RNAseq followed by bioinformatic analysis. SRS19348037 N2_Landrace N2_Landrace RNA-Seq TRANSCRIPTOMIC SINGLE CELL cDNA Illumina NovaSeq 6000 SRX22297306 2566 SRP469395 bp0 EAT (occluded and non-occluded tissue pooled) from exercised (n=4) and sedentary (n=3) female pigs had total RNA extracted with TRIzol (Thermofisher Scientific, Waltham, MA). Total RNA was quantified (Nanodrop 3300, Thermofisher, Wilmington, DE) followed by bioanalysis (Agilent 2100 Bioanalyzer, Agilent Technologies, Inc., Santa Clara, CA) for RNA quantity and quality. RNA integrity scores fell within the following range: 6.29.1. cDNA libraries were prepared, and sequencing was performed at the Molecular Genomics Core, Texas A&M University SRS19348040 Bulk_P55 2566 RNA-Seq TRANSCRIPTOMIC cDNA Illumina NovaSeq 6000 SRX22297307 O1_Landrace SRP469395 bp0 Hearts were removed, placed in Krebs bicarbonate buffer (0-4 C) and weighed. Then EAT was collected from occluded and non-occluded regions of the left circumflex coronary artery. To isolate RNA from adipose tissue, ~ 0.1 grams of snap-frozen EAT was used. The samples were then subjected to Bulk RNAseq and single Nucleus RNAseq followed by bioinformatic analysis. SRS19348044 O1_Landrace O1_Landrace RNA-Seq TRANSCRIPTOMIC SINGLE CELL cDNA Illumina NovaSeq 6000 SRX22297308 O2_Landrace SRP469395 bp0 Hearts were removed, placed in Krebs bicarbonate buffer (0-4 C) and weighed. Then EAT was collected from occluded and non-occluded regions of the left circumflex coronary artery. To isolate RNA from adipose tissue, ~ 0.1 grams of snap-frozen EAT was used. The samples were then subjected to Bulk RNAseq and single Nucleus RNAseq followed by bioinformatic analysis. SRS19348043 O2_Landrace O2_Landrace RNA-Seq TRANSCRIPTOMIC SINGLE CELL cDNA Illumina NovaSeq 6000 SRX22297309 2191 SRP469395 bp0 EAT (occluded and non-occluded tissue pooled) from exercised (n=4) and sedentary (n=3) female pigs had total RNA extracted with TRIzol (Thermofisher Scientific, Waltham, MA). Total RNA was quantified (Nanodrop 3300, Thermofisher, Wilmington, DE) followed by bioanalysis (Agilent 2100 Bioanalyzer, Agilent Technologies, Inc., Santa Clara, CA) for RNA quantity and quality. RNA integrity scores fell within the following range: 6.29.1. cDNA libraries were prepared, and sequencing was performed at the Molecular Genomics Core, Texas A&M University SRS19348041 Bulk_P38 2191 RNA-Seq TRANSCRIPTOMIC cDNA Illumina NovaSeq 6000 SRX22297310 2259 SRP469395 bp0 EAT (occluded and non-occluded tissue pooled) from exercised (n=4) and sedentary (n=3) female pigs had total RNA extracted with TRIzol (Thermofisher Scientific, Waltham, MA). Total RNA was quantified (Nanodrop 3300, Thermofisher, Wilmington, DE) followed by bioanalysis (Agilent 2100 Bioanalyzer, Agilent Technologies, Inc., Santa Clara, CA) for RNA quantity and quality. RNA integrity scores fell within the following range: 6.29.1. cDNA libraries were prepared, and sequencing was performed at the Molecular Genomics Core, Texas A&M University SRS19348051 Bulk_P39 2259 RNA-Seq TRANSCRIPTOMIC cDNA Illumina NovaSeq 6000 SRX22297311 2224 SRP469395 bp0 EAT (occluded and non-occluded tissue pooled) from exercised (n=4) and sedentary (n=3) female pigs had total RNA extracted with TRIzol (Thermofisher Scientific, Waltham, MA). Total RNA was quantified (Nanodrop 3300, Thermofisher, Wilmington, DE) followed by bioanalysis (Agilent 2100 Bioanalyzer, Agilent Technologies, Inc., Santa Clara, CA) for RNA quantity and quality. RNA integrity scores fell within the following range: 6.29.1. cDNA libraries were prepared, and sequencing was performed at the Molecular Genomics Core, Texas A&M University SRS19348047 Bulk_P42 2224 RNA-Seq TRANSCRIPTOMIC cDNA Illumina NovaSeq 6000 SRX22297312 2206 SRP469395 bp0 EAT (occluded and non-occluded tissue pooled) from exercised (n=4) and sedentary (n=3) female pigs had total RNA extracted with TRIzol (Thermofisher Scientific, Waltham, MA). Total RNA was quantified (Nanodrop 3300, Thermofisher, Wilmington, DE) followed by bioanalysis (Agilent 2100 Bioanalyzer, Agilent Technologies, Inc., Santa Clara, CA) for RNA quantity and quality. RNA integrity scores fell within the following range: 6.29.1. cDNA libraries were prepared, and sequencing was performed at the Molecular Genomics Core, Texas A&M University SRS19348055 Bulk_P43 2206 RNA-Seq TRANSCRIPTOMIC cDNA Illumina NovaSeq 6000 SRX22297313 2475 SRP469395 bp0 EAT (occluded and non-occluded tissue pooled) from exercised (n=4) and sedentary (n=3) female pigs had total RNA extracted with TRIzol (Thermofisher Scientific, Waltham, MA). Total RNA was quantified (Nanodrop 3300, Thermofisher, Wilmington, DE) followed by bioanalysis (Agilent 2100 Bioanalyzer, Agilent Technologies, Inc., Santa Clara, CA) for RNA quantity and quality. RNA integrity scores fell within the following range: 6.29.1. cDNA libraries were prepared, and sequencing was performed at the Molecular Genomics Core, Texas A&M University SRS19348048 Bulk_P46 2475 RNA-Seq TRANSCRIPTOMIC cDNA Illumina NovaSeq 6000 SRX22297314 2564 SRP469395 bp0 EAT (occluded and non-occluded tissue pooled) from exercised (n=4) and sedentary (n=3) female pigs had total RNA extracted with TRIzol (Thermofisher Scientific, Waltham, MA). Total RNA was quantified (Nanodrop 3300, Thermofisher, Wilmington, DE) followed by bioanalysis (Agilent 2100 Bioanalyzer, Agilent Technologies, Inc., Santa Clara, CA) for RNA quantity and quality. RNA integrity scores fell within the following range: 6.29.1. cDNA libraries were prepared, and sequencing was performed at the Molecular Genomics Core, Texas A&M University SRS19348054 Bulk_P53 2564 RNA-Seq TRANSCRIPTOMIC cDNA Illumina NovaSeq 6000