<?xml version="1.0" encoding="UTF-8"?>
<STUDY_SET xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <STUDY center_name="GEO" alias="GSE60476" accession="SRP045567">
    <IDENTIFIERS>
      <PRIMARY_ID>SRP045567</PRIMARY_ID>
      <EXTERNAL_ID namespace="BioProject" label="primary">PRJNA258378</EXTERNAL_ID>
      <EXTERNAL_ID namespace="GEO">GSE60476</EXTERNAL_ID>
    </IDENTIFIERS>
    <DESCRIPTOR>
      <STUDY_TITLE>SCBI Wild type and mutant Expression data</STUDY_TITLE>
      <STUDY_TYPE existing_study_type="Transcriptome Analysis"/>
      <STUDY_ABSTRACT>Purpose: To compare RNASeq data of wild type and mutants under standard growth conditions (Stationary Phase)28C for 18 h.  The mutants were found defective in genes encoding the following proteins: an alkaline metalloprotease secretion protein AprE,  GidA,  and a PIN domain protein. RNA-seq analysis provided insight into how inactivation of AprE, GidA and a PIN-domain protein influences global gene expression Overall design: mRNA profiles of wild type and mutants were generated by deep sequencing and mapped to SCBI genome by CLC Gemonic Workstation.  The transcriptome profiles of the mutants were compared to the wild type.</STUDY_ABSTRACT>
      <CENTER_PROJECT_NAME>GSE60476</CENTER_PROJECT_NAME>
    </DESCRIPTOR>
    <STUDY_LINKS>
      <STUDY_LINK>
        <XREF_LINK>
          <DB>pubmed</DB>
          <ID>25182493</ID>
        </XREF_LINK>
      </STUDY_LINK>
    </STUDY_LINKS>
  </STUDY>
</STUDY_SET>
