SRP490044 PRJNA312950 synthetic bacterium JCVI-Syn3A Genome sequencing This is a minimal bacterial cell that encodes only the 438 essential protein coding genes, 35 essential coding RNA genes from M. mycoides, and 12 kb of vector sequences for selection of the genome and for propagation in yeast and E. coli. synthetic bacterium JCVI-Syn3A pubmed 27013737