SRP503104 PRJNA1102120 MerlinS13 phosphorylation controls meningioma Wnt signaling and magnetic resonance imaging features To investigate the effect of Merlin rescue on cell proliferation in 3D, we grew subcutaneous xenografts from NF2-deficient CH-157MN meningioma cells harboring doxycycline inducible WT-Merlin. Mice were treated with or without doxycycline and Merlin induction was confirmed 24 hours after induction with Western blot. We performed bulk RNA sequencing on three Merlin-deficient tumors and four Merlin rescue tumors.