SRX1002791 GSM1663099 SRP057512 PRJNA281759 SRS916713 SAMN03496138 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA was extracted using Trizol. PolyA-selected RNA library was constructed with Illumina TruSeq RNA Sample Prep Kit. Strand-specificity was achieved through modifications of the manufacturer's protocol, as previously done in Xie eti al., Cell, 153(5):1134-1148. Illumina HiSeq 2500 gds 301663099 GSM1663099 GEO Accession GSM1663099 SRX1002792 GSM1663100 SRP057512 PRJNA281759 SRS916712 SAMN03496139 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA was extracted using Trizol. PolyA-selected RNA library was constructed with Illumina TruSeq RNA Sample Prep Kit. Strand-specificity was achieved through modifications of the manufacturer's protocol, as previously done in Xie eti al., Cell, 153(5):1134-1148. Illumina HiSeq 2500 gds 301663100 GSM1663100 GEO Accession GSM1663100 SRX1002793 GSM1663101 SRP057512 PRJNA281759 SRS916711 SAMN03496140 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA was extracted using Trizol. PolyA-selected RNA library was constructed with Illumina TruSeq RNA Sample Prep Kit. Strand-specificity was achieved through modifications of the manufacturer's protocol, as previously done in Xie eti al., Cell, 153(5):1134-1148. Illumina HiSeq 2500 gds 301663101 GSM1663101 GEO Accession GSM1663101 SRX1002794 GSM1663102 SRP057512 PRJNA281759 SRS916710 SAMN03496141 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA was extracted using Trizol. PolyA-selected RNA library was constructed with Illumina TruSeq RNA Sample Prep Kit. Strand-specificity was achieved through modifications of the manufacturer's protocol, as previously done in Xie eti al., Cell, 153(5):1134-1148. Illumina HiSeq 2500 gds 301663102 GSM1663102 GEO Accession GSM1663102 SRX1002795 GSM1663103 SRP057512 PRJNA281759 SRS916709 SAMN03496142 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA was extracted using Trizol. PolyA-selected RNA library was constructed with Illumina TruSeq RNA Sample Prep Kit. Strand-specificity was achieved through modifications of the manufacturer's protocol, as previously done in Xie eti al., Cell, 153(5):1134-1148. Illumina HiSeq 2500 gds 301663103 GSM1663103 GEO Accession GSM1663103 SRX1002796 GSM1663104 SRP057512 PRJNA281759 SRS916708 SAMN03496143 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA was extracted using Trizol. PolyA-selected RNA library was constructed with Illumina TruSeq RNA Sample Prep Kit. Strand-specificity was achieved through modifications of the manufacturer's protocol, as previously done in Xie eti al., Cell, 153(5):1134-1148. Illumina HiSeq 2500 gds 301663104 GSM1663104 GEO Accession GSM1663104 SRX1002797 GSM1663105 SRP057512 PRJNA281759 SRS916707 SAMN03496144 ChIP-Seq GENOMIC ChIP ChIP was done as previous (Hawkins et al.,Cell stem cell 2010, 6(5):479-491) , using 20ug of chromatin and 3ug of antibody was used per IP ChIP library was prepared according to Illumina protocol with modifications according to Hawkins et al.,Cell stem cell 2010, 6(5):479-491. Illumina HiSeq 2500 gds 301663105 GSM1663105 GEO Accession GSM1663105 SRX1002798 GSM1663106 SRP057512 PRJNA281759 SRS916706 SAMN03496145 ChIP-Seq GENOMIC ChIP ChIP was done as previous (Hawkins et al.,Cell stem cell 2010, 6(5):479-491) , using 20ug of chromatin and 3ug of antibody was used per IP ChIP library was prepared according to Illumina protocol with modifications according to Hawkins et al.,Cell stem cell 2010, 6(5):479-491. Illumina HiSeq 2500 gds 301663106 GSM1663106 GEO Accession GSM1663106 SRX1002799 GSM1663107 SRP057512 PRJNA281759 SRS916703 SAMN03496146 ChIP-Seq GENOMIC ChIP ChIP was done as previous (Hawkins et al.,Cell stem cell 2010, 6(5):479-491) , using 20ug of chromatin and 3ug of antibody was used per IP ChIP library was prepared according to Illumina protocol with modifications according to Hawkins et al.,Cell stem cell 2010, 6(5):479-491. Illumina HiSeq 2500 gds 301663107 GSM1663107 GEO Accession GSM1663107 SRX1002800 GSM1663108 SRP057512 PRJNA281759 SRS916702 SAMN03496115 ChIP-Seq GENOMIC ChIP ChIP was done as previous (Hawkins et al.,Cell stem cell 2010, 6(5):479-491) , using 20ug of chromatin and 3ug of antibody was used per IP ChIP library was prepared according to Illumina protocol with modifications according to Hawkins et al.,Cell stem cell 2010, 6(5):479-491. Illumina HiSeq 2500 gds 301663108 GSM1663108 GEO Accession GSM1663108 SRX1002801 GSM1663109 SRP057512 PRJNA281759 SRS916701 SAMN03496116 ChIP-Seq GENOMIC ChIP ChIP was done as previous (Hawkins et al.,Cell stem cell 2010, 6(5):479-491) , using 20ug of chromatin and 3ug of antibody was used per IP ChIP library was prepared according to Illumina protocol with modifications according to Hawkins et al.,Cell stem cell 2010, 6(5):479-491. Illumina HiSeq 2500 gds 301663109 GSM1663109 GEO Accession GSM1663109 SRX1002802 GSM1663110 SRP057512 PRJNA281759 SRS916700 SAMN03496117 ChIP-Seq GENOMIC ChIP ChIP was done as previous (Hawkins et al.,Cell stem cell 2010, 6(5):479-491) , using 20ug of chromatin and 3ug of antibody was used per IP ChIP library was prepared according to Illumina protocol with modifications according to Hawkins et al.,Cell stem cell 2010, 6(5):479-491. Illumina HiSeq 2500 gds 301663110 GSM1663110 GEO Accession GSM1663110 SRX1123617 GSM1835787 SRP057512 PRJNA281759 SRS1016129 SAMN03943706 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA was extracted using Trizol. PolyA-selected RNA library was constructed with Illumina TruSeq Stranded mRNA library prep kit. NextSeq 500 gds 301835787 GSM1835787 GEO Accession GSM1835787 SRX1123618 GSM1835788 SRP057512 PRJNA281759 SRS1016128 SAMN03943707 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA was extracted using Trizol. PolyA-selected RNA library was constructed with Illumina TruSeq Stranded mRNA library prep kit. NextSeq 500 gds 301835788 GSM1835788 GEO Accession GSM1835788 SRX1123619 GSM1835789 SRP057512 PRJNA281759 SRS1016127 SAMN03943708 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA was extracted using Trizol. PolyA-selected RNA library was constructed with Illumina TruSeq Stranded mRNA library prep kit. NextSeq 500 gds 301835789 GSM1835789 GEO Accession GSM1835789 SRX1123620 GSM1835790 SRP057512 PRJNA281759 SRS1016126 SAMN03943709 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA was extracted using Trizol. PolyA-selected RNA library was constructed with Illumina TruSeq Stranded mRNA library prep kit. NextSeq 500 gds 301835790 GSM1835790 GEO Accession GSM1835790