SRX1212644 GSM1873343 SRP063511 SRS1061457 GSM1873343 RIP-Seq TRANSCRIPTOMIC other Cells were crosslinked with 0.3% formaldehyde for 10 min at room temperature and lysed with RIPA lysis buffer for 10 min on ice before sonication. The supernatant was collected and incubated with RIP antibodies for 4 to 6 hours. After washing with RIPA buffer, RNA was eluted from the beads with 100 µl NaHCO3 and 1% SDS in the presence of proteinase K and RNase inhibitor at room temperature for 10 min with occasional vortex. The eluted material was de-crosslinked at 65°C for 45 – 60 min before purification of RNA using Trizol LS reagent (Life Technology). DNase I treatment was performed to remove any residual DNA. RNA-seq libraries were constructed with TruSeq Stranded mRNA Library Prep Kit from Illumina according to the manufacturer’s manual. Illumina HiSeq 2000 gds 301873343 GEO Accession GSM1873343 SRX1212645 GSM1873344 SRP063511 SRS1061456 GSM1873344 RIP-Seq TRANSCRIPTOMIC other Cells were crosslinked with 0.3% formaldehyde for 10 min at room temperature and lysed with RIPA lysis buffer for 10 min on ice before sonication. The supernatant was collected and incubated with RIP antibodies for 4 to 6 hours. After washing with RIPA buffer, RNA was eluted from the beads with 100 µl NaHCO3 and 1% SDS in the presence of proteinase K and RNase inhibitor at room temperature for 10 min with occasional vortex. The eluted material was de-crosslinked at 65°C for 45 – 60 min before purification of RNA using Trizol LS reagent (Life Technology). DNase I treatment was performed to remove any residual DNA. RNA-seq libraries were constructed with TruSeq Stranded mRNA Library Prep Kit from Illumina according to the manufacturer’s manual. Illumina HiSeq 2000 gds 301873344 GEO Accession GSM1873344 SRX1212646 GSM1873345 SRP063511 SRS1061455 GSM1873345 RIP-Seq TRANSCRIPTOMIC other Cells were crosslinked with 0.3% formaldehyde for 10 min at room temperature and lysed with RIPA lysis buffer for 10 min on ice before sonication. The supernatant was collected and incubated with RIP antibodies for 4 to 6 hours. After washing with RIPA buffer, RNA was eluted from the beads with 100 µl NaHCO3 and 1% SDS in the presence of proteinase K and RNase inhibitor at room temperature for 10 min with occasional vortex. The eluted material was de-crosslinked at 65°C for 45 – 60 min before purification of RNA using Trizol LS reagent (Life Technology). DNase I treatment was performed to remove any residual DNA. RNA-seq libraries were constructed with TruSeq Stranded mRNA Library Prep Kit from Illumina according to the manufacturer’s manual. Illumina HiSeq 2000 gds 301873345 GEO Accession GSM1873345 SRX1212647 GSM1873346 SRP063511 SRS1061454 GSM1873346 RIP-Seq TRANSCRIPTOMIC other Cells were crosslinked with 0.3% formaldehyde for 10 min at room temperature and lysed with RIPA lysis buffer for 10 min on ice before sonication. The supernatant was collected and incubated with RIP antibodies for 4 to 6 hours. After washing with RIPA buffer, RNA was eluted from the beads with 100 µl NaHCO3 and 1% SDS in the presence of proteinase K and RNase inhibitor at room temperature for 10 min with occasional vortex. The eluted material was de-crosslinked at 65°C for 45 – 60 min before purification of RNA using Trizol LS reagent (Life Technology). DNase I treatment was performed to remove any residual DNA. RNA-seq libraries were constructed with TruSeq Stranded mRNA Library Prep Kit from Illumina according to the manufacturer’s manual. Illumina HiSeq 2000 gds 301873346 GEO Accession GSM1873346