SRX1225234 GSM1875307 SRP063623 SRS1065128 GSM1875307 RNA-Seq TRANSCRIPTOMIC cDNA Cells were immediately lysed and total RNA was extracted using the PrepEASE RNA Spin Kit according to the manufacturer's protocols. Libraries were constructed using standard Illumina protocols. Illumina HiSeq 2500 gds 301875307 GEO Accession GSM1875307 SRX1225235 GSM1875308 SRP063623 SRS1065158 GSM1875308 RNA-Seq TRANSCRIPTOMIC cDNA Cells were immediately lysed and total RNA was extracted using the PrepEASE RNA Spin Kit according to the manufacturer's protocols. Libraries were constructed using standard Illumina protocols. Illumina HiSeq 2500 gds 301875308 GEO Accession GSM1875308 SRX1225236 GSM1875309 SRP063623 SRS1065156 GSM1875309 RNA-Seq TRANSCRIPTOMIC cDNA Cells were immediately lysed and total RNA was extracted using the PrepEASE RNA Spin Kit according to the manufacturer's protocols. Libraries were constructed using standard Illumina protocols. Illumina HiSeq 2500 gds 301875309 GEO Accession GSM1875309 SRX1225237 GSM1875310 SRP063623 SRS1065157 GSM1875310 RNA-Seq TRANSCRIPTOMIC cDNA Cells were immediately lysed and total RNA was extracted using the PrepEASE RNA Spin Kit according to the manufacturer's protocols. Libraries were constructed using standard Illumina protocols. Illumina HiSeq 2500 gds 301875310 GEO Accession GSM1875310 SRX1225238 GSM1875311 SRP063623 SRS1065155 GSM1875311 RNA-Seq TRANSCRIPTOMIC cDNA Cells were immediately lysed and total RNA was extracted using the PrepEASE RNA Spin Kit according to the manufacturer's protocols. Libraries were constructed using standard Illumina protocols. Illumina HiSeq 2500 gds 301875311 GEO Accession GSM1875311 SRX1225239 GSM1875312 SRP063623 SRS1065154 GSM1875312 RNA-Seq TRANSCRIPTOMIC cDNA Cells were immediately lysed and total RNA was extracted using the PrepEASE RNA Spin Kit according to the manufacturer's protocols. Libraries were constructed using standard Illumina protocols. Illumina HiSeq 2500 gds 301875312 GEO Accession GSM1875312 SRX1225240 GSM1875313 SRP063623 SRS1065153 GSM1875313 RNA-Seq TRANSCRIPTOMIC cDNA Cells were immediately lysed and total RNA was extracted using the PrepEASE RNA Spin Kit according to the manufacturer's protocols. Libraries were constructed using standard Illumina protocols. Illumina HiSeq 2500 gds 301875313 GEO Accession GSM1875313 SRX1225241 GSM1875314 SRP063623 SRS1065152 GSM1875314 RNA-Seq TRANSCRIPTOMIC cDNA Cells were immediately lysed and total RNA was extracted using the PrepEASE RNA Spin Kit according to the manufacturer's protocols. Libraries were constructed using standard Illumina protocols. Illumina HiSeq 2500 gds 301875314 GEO Accession GSM1875314 SRX1225242 GSM1875315 SRP063623 SRS1065151 GSM1875315 RNA-Seq TRANSCRIPTOMIC cDNA Cells were immediately lysed and total RNA was extracted using the PrepEASE RNA Spin Kit according to the manufacturer's protocols. Libraries were constructed using standard Illumina protocols. Illumina HiSeq 2500 gds 301875315 GEO Accession GSM1875315 SRX1225243 GSM1875316 SRP063623 SRS1065150 GSM1875316 RNA-Seq TRANSCRIPTOMIC cDNA Cells were immediately lysed and total RNA was extracted using the PrepEASE RNA Spin Kit according to the manufacturer's protocols. Libraries were constructed using standard Illumina protocols. Illumina HiSeq 2500 gds 301875316 GEO Accession GSM1875316 SRX1225244 GSM1875317 SRP063623 SRS1065149 GSM1875317 RNA-Seq TRANSCRIPTOMIC cDNA Cells were immediately lysed and total RNA was extracted using the PrepEASE RNA Spin Kit according to the manufacturer's protocols. Libraries were constructed using standard Illumina protocols. Illumina HiSeq 2500 gds 301875317 GEO Accession GSM1875317 SRX1225245 GSM1875318 SRP063623 SRS1065148 GSM1875318 RNA-Seq TRANSCRIPTOMIC cDNA Cells were immediately lysed and total RNA was extracted using the PrepEASE RNA Spin Kit according to the manufacturer's protocols. Libraries were constructed using standard Illumina protocols. Illumina HiSeq 2500 gds 301875318 GEO Accession GSM1875318 SRX1225246 GSM1875319 SRP063623 SRS1065147 GSM1875319 RNA-Seq TRANSCRIPTOMIC cDNA Cells were immediately lysed and total RNA was extracted using the PrepEASE RNA Spin Kit according to the manufacturer's protocols. Libraries were constructed using standard Illumina protocols. Illumina HiSeq 2500 gds 301875319 GEO Accession GSM1875319 SRX1225247 GSM1875320 SRP063623 SRS1065130 GSM1875320 RNA-Seq TRANSCRIPTOMIC cDNA Cells were immediately lysed and total RNA was extracted using the PrepEASE RNA Spin Kit according to the manufacturer's protocols. Libraries were constructed using standard Illumina protocols. Illumina HiSeq 2500 gds 301875320 GEO Accession GSM1875320 SRX1225248 GSM1875321 SRP063623 SRS1065146 GSM1875321 RNA-Seq TRANSCRIPTOMIC cDNA Cells were immediately lysed and total RNA was extracted using the PrepEASE RNA Spin Kit according to the manufacturer's protocols. Libraries were constructed using standard Illumina protocols. Illumina HiSeq 2500 gds 301875321 GEO Accession GSM1875321 SRX1225249 GSM1875322 SRP063623 SRS1065129 GSM1875322 RNA-Seq TRANSCRIPTOMIC cDNA Cells were immediately lysed and total RNA was extracted using the PrepEASE RNA Spin Kit according to the manufacturer's protocols. Libraries were constructed using standard Illumina protocols. Illumina HiSeq 2500 gds 301875322 GEO Accession GSM1875322 SRX1225250 GSM1875323 SRP063623 SRS1065145 GSM1875323 RNA-Seq TRANSCRIPTOMIC cDNA Cells were immediately lysed and total RNA was extracted using the PrepEASE RNA Spin Kit according to the manufacturer's protocols. Libraries were constructed using standard Illumina protocols. Illumina HiSeq 2500 gds 301875323 GEO Accession GSM1875323 SRX1225251 GSM1875324 SRP063623 SRS1065144 GSM1875324 RNA-Seq TRANSCRIPTOMIC cDNA Cells were immediately lysed and total RNA was extracted using the PrepEASE RNA Spin Kit according to the manufacturer's protocols. Libraries were constructed using standard Illumina protocols. Illumina HiSeq 2500 gds 301875324 GEO Accession GSM1875324 SRX1225252 GSM1875325 SRP063623 SRS1065143 GSM1875325 RNA-Seq TRANSCRIPTOMIC cDNA Cells were immediately lysed and total RNA was extracted using the PrepEASE RNA Spin Kit according to the manufacturer's protocols. Libraries were constructed using standard Illumina protocols. Illumina HiSeq 2500 gds 301875325 GEO Accession GSM1875325 SRX1225253 GSM1875326 SRP063623 SRS1065142 GSM1875326 RNA-Seq TRANSCRIPTOMIC cDNA Cells were immediately lysed and total RNA was extracted using the PrepEASE RNA Spin Kit according to the manufacturer's protocols. Libraries were constructed using standard Illumina protocols. Illumina HiSeq 2500 gds 301875326 GEO Accession GSM1875326 SRX1225254 GSM1875327 SRP063623 SRS1065141 GSM1875327 RNA-Seq TRANSCRIPTOMIC cDNA Cells were immediately lysed and total RNA was extracted using the PrepEASE RNA Spin Kit according to the manufacturer's protocols. Libraries were constructed using standard Illumina protocols. Illumina HiSeq 2500 gds 301875327 GEO Accession GSM1875327 SRX1225255 GSM1875328 SRP063623 SRS1065140 GSM1875328 RNA-Seq TRANSCRIPTOMIC cDNA Cells were immediately lysed and total RNA was extracted using the PrepEASE RNA Spin Kit according to the manufacturer's protocols. Libraries were constructed using standard Illumina protocols. Illumina HiSeq 2500 gds 301875328 GEO Accession GSM1875328 SRX1225256 GSM1875329 SRP063623 SRS1065139 GSM1875329 RNA-Seq TRANSCRIPTOMIC cDNA Cells were immediately lysed and total RNA was extracted using the PrepEASE RNA Spin Kit according to the manufacturer's protocols. Libraries were constructed using standard Illumina protocols. Illumina HiSeq 2500 gds 301875329 GEO Accession GSM1875329 SRX1225257 GSM1875330 SRP063623 SRS1065138 GSM1875330 RNA-Seq TRANSCRIPTOMIC cDNA Cells were immediately lysed and total RNA was extracted using the PrepEASE RNA Spin Kit according to the manufacturer's protocols. Libraries were constructed using standard Illumina protocols. Illumina HiSeq 2500 gds 301875330 GEO Accession GSM1875330 SRX1225258 GSM1875331 SRP063623 SRS1065137 GSM1875331 RNA-Seq TRANSCRIPTOMIC cDNA Cells were immediately lysed and total RNA was extracted using the PrepEASE RNA Spin Kit according to the manufacturer's protocols. Libraries were constructed using standard Illumina protocols. Illumina HiSeq 2500 gds 301875331 GEO Accession GSM1875331 SRX1225259 GSM1875332 SRP063623 SRS1065136 GSM1875332 RNA-Seq TRANSCRIPTOMIC cDNA Cells were immediately lysed and total RNA was extracted using the PrepEASE RNA Spin Kit according to the manufacturer's protocols. Libraries were constructed using standard Illumina protocols. Illumina HiSeq 2500 gds 301875332 GEO Accession GSM1875332 SRX1225260 GSM1875333 SRP063623 SRS1065135 GSM1875333 RNA-Seq TRANSCRIPTOMIC cDNA Cells were immediately lysed and total RNA was extracted using the PrepEASE RNA Spin Kit according to the manufacturer's protocols. Libraries were constructed using standard Illumina protocols. Illumina HiSeq 2500 gds 301875333 GEO Accession GSM1875333 SRX1225261 GSM1875334 SRP063623 SRS1065134 GSM1875334 RNA-Seq TRANSCRIPTOMIC cDNA Cells were immediately lysed and total RNA was extracted using the PrepEASE RNA Spin Kit according to the manufacturer's protocols. Libraries were constructed using standard Illumina protocols. Illumina HiSeq 2500 gds 301875334 GEO Accession GSM1875334 SRX1225262 GSM1875335 SRP063623 SRS1065133 GSM1875335 RNA-Seq TRANSCRIPTOMIC cDNA Cells were immediately lysed and total RNA was extracted using the PrepEASE RNA Spin Kit according to the manufacturer's protocols. Libraries were constructed using standard Illumina protocols. Illumina HiSeq 2500 gds 301875335 GEO Accession GSM1875335 SRX1225263 GSM1875336 SRP063623 SRS1065132 GSM1875336 RNA-Seq TRANSCRIPTOMIC cDNA Cells were immediately lysed and total RNA was extracted using the PrepEASE RNA Spin Kit according to the manufacturer's protocols. Libraries were constructed using standard Illumina protocols. Illumina HiSeq 2500 gds 301875336 GEO Accession GSM1875336 SRX1225264 GSM1875337 SRP063623 SRS1065131 GSM1875337 RNA-Seq TRANSCRIPTOMIC cDNA Cells were immediately lysed and total RNA was extracted using the PrepEASE RNA Spin Kit according to the manufacturer's protocols. Libraries were constructed using standard Illumina protocols. Illumina HiSeq 2500 gds 301875337 GEO Accession GSM1875337 SRX1592610 GSM2066429 SRP063623 SRS1303669 GSM2066429 ChIP-Seq GENOMIC ChIP Cells were grown to 90–95% confluence, fixed with 1% formaldehyde for 15 min at room temperature followed by addition of glycine (1.25mM) for 10 minutes to stop cross linking. Nuclei were prepared and sonicated in lysis buffer (150 mM NaCl, 1% Triton X-100, 20 mM Tris pH 8.0, 0.1% SDS) using a Bioruptor to fragment chromatin to less than 500 base pairs (bp). Chromatin was pre-cleared with 35 μl Protein-G Dyna magnetic beads, and then immunoprecipitated with 5 μg of antibody over night at 4 °C. The chromatin antibody mix was incubated with 35 μl protein G-conjugated Dyna beads for 4 h at 4 °C, washed three times with wash buffer (1% Triton X-100, 50 mM Tris pH 8.0, 10% glycerol) with increasing concentrations of NaCl (150 mM, 300 mM and 400 mM), and two times with Tris-EDTA buffer. DNA was eluted in 1% SDS in Tris-EDTA buffer for 45 min at 37 °C, crosslinking was reversed overnight at 65 °C, and DNA was purified using Qiagen columns. For each ChIP, one fifth of the cells from 15cm plates were used. Illumina HiSeq 2000 gds 302066429 GEO Accession GSM2066429 SRX1592611 GSM2066430 SRP063623 SRS1303668 GSM2066430 ChIP-Seq GENOMIC ChIP Cells were grown to 90–95% confluence, fixed with 1% formaldehyde for 15 min at room temperature followed by addition of glycine (1.25mM) for 10 minutes to stop cross linking. Nuclei were prepared and sonicated in lysis buffer (150 mM NaCl, 1% Triton X-100, 20 mM Tris pH 8.0, 0.1% SDS) using a Bioruptor to fragment chromatin to less than 500 base pairs (bp). Chromatin was pre-cleared with 35 μl Protein-G Dyna magnetic beads, and then immunoprecipitated with 5 μg of antibody over night at 4 °C. The chromatin antibody mix was incubated with 35 μl protein G-conjugated Dyna beads for 4 h at 4 °C, washed three times with wash buffer (1% Triton X-100, 50 mM Tris pH 8.0, 10% glycerol) with increasing concentrations of NaCl (150 mM, 300 mM and 400 mM), and two times with Tris-EDTA buffer. DNA was eluted in 1% SDS in Tris-EDTA buffer for 45 min at 37 °C, crosslinking was reversed overnight at 65 °C, and DNA was purified using Qiagen columns. For each ChIP, one fifth of the cells from 15cm plates were used. Illumina HiSeq 2000 gds 302066430 GEO Accession GSM2066430 SRX1592612 GSM2066431 SRP063623 SRS1303667 GSM2066431 ChIP-Seq GENOMIC ChIP Cells were grown to 90–95% confluence, fixed with 1% formaldehyde for 15 min at room temperature followed by addition of glycine (1.25mM) for 10 minutes to stop cross linking. Nuclei were prepared and sonicated in lysis buffer (150 mM NaCl, 1% Triton X-100, 20 mM Tris pH 8.0, 0.1% SDS) using a Bioruptor to fragment chromatin to less than 500 base pairs (bp). Chromatin was pre-cleared with 35 μl Protein-G Dyna magnetic beads, and then immunoprecipitated with 5 μg of antibody over night at 4 °C. The chromatin antibody mix was incubated with 35 μl protein G-conjugated Dyna beads for 4 h at 4 °C, washed three times with wash buffer (1% Triton X-100, 50 mM Tris pH 8.0, 10% glycerol) with increasing concentrations of NaCl (150 mM, 300 mM and 400 mM), and two times with Tris-EDTA buffer. DNA was eluted in 1% SDS in Tris-EDTA buffer for 45 min at 37 °C, crosslinking was reversed overnight at 65 °C, and DNA was purified using Qiagen columns. For each ChIP, one fifth of the cells from 15cm plates were used. Illumina HiSeq 2000 gds 302066431 GEO Accession GSM2066431 SRX1592613 GSM2066432 SRP063623 SRS1303666 GSM2066432 ChIP-Seq GENOMIC ChIP Cells were grown to 90–95% confluence, fixed with 1% formaldehyde for 15 min at room temperature followed by addition of glycine (1.25mM) for 10 minutes to stop cross linking. Nuclei were prepared and sonicated in lysis buffer (150 mM NaCl, 1% Triton X-100, 20 mM Tris pH 8.0, 0.1% SDS) using a Bioruptor to fragment chromatin to less than 500 base pairs (bp). Chromatin was pre-cleared with 35 μl Protein-G Dyna magnetic beads, and then immunoprecipitated with 5 μg of antibody over night at 4 °C. The chromatin antibody mix was incubated with 35 μl protein G-conjugated Dyna beads for 4 h at 4 °C, washed three times with wash buffer (1% Triton X-100, 50 mM Tris pH 8.0, 10% glycerol) with increasing concentrations of NaCl (150 mM, 300 mM and 400 mM), and two times with Tris-EDTA buffer. DNA was eluted in 1% SDS in Tris-EDTA buffer for 45 min at 37 °C, crosslinking was reversed overnight at 65 °C, and DNA was purified using Qiagen columns. For each ChIP, one fifth of the cells from 15cm plates were used. Illumina HiSeq 2000 gds 302066432 GEO Accession GSM2066432 SRX1592614 GSM2066433 SRP063623 SRS1303665 GSM2066433 ChIP-Seq GENOMIC ChIP Cells were grown to 90–95% confluence, fixed with 1% formaldehyde for 15 min at room temperature followed by addition of glycine (1.25mM) for 10 minutes to stop cross linking. Nuclei were prepared and sonicated in lysis buffer (150 mM NaCl, 1% Triton X-100, 20 mM Tris pH 8.0, 0.1% SDS) using a Bioruptor to fragment chromatin to less than 500 base pairs (bp). Chromatin was pre-cleared with 35 μl Protein-G Dyna magnetic beads, and then immunoprecipitated with 5 μg of antibody over night at 4 °C. The chromatin antibody mix was incubated with 35 μl protein G-conjugated Dyna beads for 4 h at 4 °C, washed three times with wash buffer (1% Triton X-100, 50 mM Tris pH 8.0, 10% glycerol) with increasing concentrations of NaCl (150 mM, 300 mM and 400 mM), and two times with Tris-EDTA buffer. DNA was eluted in 1% SDS in Tris-EDTA buffer for 45 min at 37 °C, crosslinking was reversed overnight at 65 °C, and DNA was purified using Qiagen columns. For each ChIP, one fifth of the cells from 15cm plates were used. Illumina HiSeq 2000 gds 302066433 GEO Accession GSM2066433 SRX1592615 GSM2066434 SRP063623 SRS1303664 GSM2066434 ChIP-Seq GENOMIC ChIP Cells were grown to 90–95% confluence, fixed with 1% formaldehyde for 15 min at room temperature followed by addition of glycine (1.25mM) for 10 minutes to stop cross linking. Nuclei were prepared and sonicated in lysis buffer (150 mM NaCl, 1% Triton X-100, 20 mM Tris pH 8.0, 0.1% SDS) using a Bioruptor to fragment chromatin to less than 500 base pairs (bp). Chromatin was pre-cleared with 35 μl Protein-G Dyna magnetic beads, and then immunoprecipitated with 5 μg of antibody over night at 4 °C. The chromatin antibody mix was incubated with 35 μl protein G-conjugated Dyna beads for 4 h at 4 °C, washed three times with wash buffer (1% Triton X-100, 50 mM Tris pH 8.0, 10% glycerol) with increasing concentrations of NaCl (150 mM, 300 mM and 400 mM), and two times with Tris-EDTA buffer. DNA was eluted in 1% SDS in Tris-EDTA buffer for 45 min at 37 °C, crosslinking was reversed overnight at 65 °C, and DNA was purified using Qiagen columns. For each ChIP, one fifth of the cells from 15cm plates were used. Illumina HiSeq 2000 gds 302066434 GEO Accession GSM2066434 SRX1592616 GSM2066435 SRP063623 SRS1303663 GSM2066435 ChIP-Seq GENOMIC ChIP Cells were grown to 90–95% confluence, fixed with 1% formaldehyde for 15 min at room temperature followed by addition of glycine (1.25mM) for 10 minutes to stop cross linking. Nuclei were prepared and sonicated in lysis buffer (150 mM NaCl, 1% Triton X-100, 20 mM Tris pH 8.0, 0.1% SDS) using a Bioruptor to fragment chromatin to less than 500 base pairs (bp). Chromatin was pre-cleared with 35 μl Protein-G Dyna magnetic beads, and then immunoprecipitated with 5 μg of antibody over night at 4 °C. The chromatin antibody mix was incubated with 35 μl protein G-conjugated Dyna beads for 4 h at 4 °C, washed three times with wash buffer (1% Triton X-100, 50 mM Tris pH 8.0, 10% glycerol) with increasing concentrations of NaCl (150 mM, 300 mM and 400 mM), and two times with Tris-EDTA buffer. DNA was eluted in 1% SDS in Tris-EDTA buffer for 45 min at 37 °C, crosslinking was reversed overnight at 65 °C, and DNA was purified using Qiagen columns. For each ChIP, one fifth of the cells from 15cm plates were used. Illumina HiSeq 2000 gds 302066435 GEO Accession GSM2066435 SRX1592617 GSM2066436 SRP063623 SRS1303662 GSM2066436 ChIP-Seq GENOMIC ChIP Cells were grown to 90–95% confluence, fixed with 1% formaldehyde for 15 min at room temperature followed by addition of glycine (1.25mM) for 10 minutes to stop cross linking. Nuclei were prepared and sonicated in lysis buffer (150 mM NaCl, 1% Triton X-100, 20 mM Tris pH 8.0, 0.1% SDS) using a Bioruptor to fragment chromatin to less than 500 base pairs (bp). Chromatin was pre-cleared with 35 μl Protein-G Dyna magnetic beads, and then immunoprecipitated with 5 μg of antibody over night at 4 °C. The chromatin antibody mix was incubated with 35 μl protein G-conjugated Dyna beads for 4 h at 4 °C, washed three times with wash buffer (1% Triton X-100, 50 mM Tris pH 8.0, 10% glycerol) with increasing concentrations of NaCl (150 mM, 300 mM and 400 mM), and two times with Tris-EDTA buffer. DNA was eluted in 1% SDS in Tris-EDTA buffer for 45 min at 37 °C, crosslinking was reversed overnight at 65 °C, and DNA was purified using Qiagen columns. For each ChIP, one fifth of the cells from 15cm plates were used. Illumina HiSeq 2000 gds 302066436 GEO Accession GSM2066436 SRX1592618 GSM2066437 SRP063623 SRS1303661 GSM2066437 ChIP-Seq GENOMIC ChIP Cells were grown to 90–95% confluence, fixed with 1% formaldehyde for 15 min at room temperature followed by addition of glycine (1.25mM) for 10 minutes to stop cross linking. Nuclei were prepared and sonicated in lysis buffer (150 mM NaCl, 1% Triton X-100, 20 mM Tris pH 8.0, 0.1% SDS) using a Bioruptor to fragment chromatin to less than 500 base pairs (bp). Chromatin was pre-cleared with 35 μl Protein-G Dyna magnetic beads, and then immunoprecipitated with 5 μg of antibody over night at 4 °C. The chromatin antibody mix was incubated with 35 μl protein G-conjugated Dyna beads for 4 h at 4 °C, washed three times with wash buffer (1% Triton X-100, 50 mM Tris pH 8.0, 10% glycerol) with increasing concentrations of NaCl (150 mM, 300 mM and 400 mM), and two times with Tris-EDTA buffer. DNA was eluted in 1% SDS in Tris-EDTA buffer for 45 min at 37 °C, crosslinking was reversed overnight at 65 °C, and DNA was purified using Qiagen columns. For each ChIP, one fifth of the cells from 15cm plates were used. Illumina HiSeq 2000 gds 302066437 GEO Accession GSM2066437 SRX1592619 GSM2066438 SRP063623 SRS1303660 GSM2066438 ChIP-Seq GENOMIC ChIP Cells were grown to 90–95% confluence, fixed with 1% formaldehyde for 15 min at room temperature followed by addition of glycine (1.25mM) for 10 minutes to stop cross linking. Nuclei were prepared and sonicated in lysis buffer (150 mM NaCl, 1% Triton X-100, 20 mM Tris pH 8.0, 0.1% SDS) using a Bioruptor to fragment chromatin to less than 500 base pairs (bp). Chromatin was pre-cleared with 35 μl Protein-G Dyna magnetic beads, and then immunoprecipitated with 5 μg of antibody over night at 4 °C. The chromatin antibody mix was incubated with 35 μl protein G-conjugated Dyna beads for 4 h at 4 °C, washed three times with wash buffer (1% Triton X-100, 50 mM Tris pH 8.0, 10% glycerol) with increasing concentrations of NaCl (150 mM, 300 mM and 400 mM), and two times with Tris-EDTA buffer. DNA was eluted in 1% SDS in Tris-EDTA buffer for 45 min at 37 °C, crosslinking was reversed overnight at 65 °C, and DNA was purified using Qiagen columns. For each ChIP, one fifth of the cells from 15cm plates were used. Illumina HiSeq 2000 gds 302066438 GEO Accession GSM2066438 SRX1592620 GSM2066439 SRP063623 SRS1303659 GSM2066439 ChIP-Seq GENOMIC ChIP Cells were grown to 90–95% confluence, fixed with 1% formaldehyde for 15 min at room temperature followed by addition of glycine (1.25mM) for 10 minutes to stop cross linking. Nuclei were prepared and sonicated in lysis buffer (150 mM NaCl, 1% Triton X-100, 20 mM Tris pH 8.0, 0.1% SDS) using a Bioruptor to fragment chromatin to less than 500 base pairs (bp). Chromatin was pre-cleared with 35 μl Protein-G Dyna magnetic beads, and then immunoprecipitated with 5 μg of antibody over night at 4 °C. The chromatin antibody mix was incubated with 35 μl protein G-conjugated Dyna beads for 4 h at 4 °C, washed three times with wash buffer (1% Triton X-100, 50 mM Tris pH 8.0, 10% glycerol) with increasing concentrations of NaCl (150 mM, 300 mM and 400 mM), and two times with Tris-EDTA buffer. DNA was eluted in 1% SDS in Tris-EDTA buffer for 45 min at 37 °C, crosslinking was reversed overnight at 65 °C, and DNA was purified using Qiagen columns. For each ChIP, one fifth of the cells from 15cm plates were used. Illumina HiSeq 2000 gds 302066439 GEO Accession GSM2066439 SRX1592621 GSM2066440 SRP063623 SRS1303658 GSM2066440 ChIP-Seq GENOMIC ChIP Cells were grown to 90–95% confluence, fixed with 1% formaldehyde for 15 min at room temperature followed by addition of glycine (1.25mM) for 10 minutes to stop cross linking. Nuclei were prepared and sonicated in lysis buffer (150 mM NaCl, 1% Triton X-100, 20 mM Tris pH 8.0, 0.1% SDS) using a Bioruptor to fragment chromatin to less than 500 base pairs (bp). Chromatin was pre-cleared with 35 μl Protein-G Dyna magnetic beads, and then immunoprecipitated with 5 μg of antibody over night at 4 °C. The chromatin antibody mix was incubated with 35 μl protein G-conjugated Dyna beads for 4 h at 4 °C, washed three times with wash buffer (1% Triton X-100, 50 mM Tris pH 8.0, 10% glycerol) with increasing concentrations of NaCl (150 mM, 300 mM and 400 mM), and two times with Tris-EDTA buffer. DNA was eluted in 1% SDS in Tris-EDTA buffer for 45 min at 37 °C, crosslinking was reversed overnight at 65 °C, and DNA was purified using Qiagen columns. For each ChIP, one fifth of the cells from 15cm plates were used. Illumina HiSeq 2000 gds 302066440 GEO Accession GSM2066440