SRP035283 PRJNA234047 Clinical validation of next-generation sequencing approaches for pathogen diagnosis The Chiu laboratory and UCSF-Abbott Viral Diagnostics and Discovery Center (VDDC) at University of California, San Francisco applies unbiased next-generation sequencing (NGS) approaches to identify known as well as novel pathogens in patient clinical samples with acute infections. Here we present clinical sample data used for validation and testing of NGS-based clinical assays for infectious disease diagnosis. Clinical validation of next-generation sequencing approaches for pathogen diagnosis UCSF-Abbott Viral Diagnostics and Discovery Center http://vddc.ucsf.edu/ SRP064607 SRX1315210 PRJNA298217 Metagenomic Next-Generation Sequencing for Infectious Disease Diagnosis This is a prospective study at UCSF using metagenomic next-generation sequencing and SURPI bioinformatics analysis to identify pathogens in clinical samples (cerebrospinal fluid, plasma, and bronchoalveolar fluid) for diagnosing infections in hospitalized patients human metagenome parent_bioproject PRJNA234047