SRX1428005 1 SRP065769 PRJNA298763 DNA from 4 IPs was pooled for each library generated with the NEB Next DNA Library Prep Master Mix (NEB E6040) according to manufacturer’s instructions. Libraries were amplified using 18 PCR cycles, purified using Agencourt AMPure XP SPRI beads (Beckman Coulter A63881) and size-selected on an agarose gel. DNA was extracted using the QiaQuick gel extraction kit (Qiagen) and its concentration determined using the KAPA Illumina SYBR Universal Lid Q Kit (KAPA Biosystems KK4824) and Bioanalyzer 2100 system (Agilent). SRS1146197 SAMN04235858 1 ChIP-Seq GENOMIC ChIP Illumina HiSeq 2500 SRX1428006 2 SRP065769 PRJNA298763 DNA from 4 IPs was pooled for each library generated with the NEB Next DNA Library Prep Master Mix (NEB E6040) according to manufacturer’s instructions. Libraries were amplified using 18 PCR cycles, purified using Agencourt AMPure XP SPRI beads (Beckman Coulter A63881) and size-selected on an agarose gel. DNA was extracted using the QiaQuick gel extraction kit (Qiagen) and its concentration determined using the KAPA Illumina SYBR Universal Lid Q Kit (KAPA Biosystems KK4824) and Bioanalyzer 2100 system (Agilent). SRS1146198 SAMN04235859 2 ChIP-Seq GENOMIC ChIP Illumina HiSeq 2500 SRX1428007 3 SRP065769 PRJNA298763 DNA from 4 IPs was pooled for each library generated with the NEB Next DNA Library Prep Master Mix (NEB E6040) according to manufacturer’s instructions. Libraries were amplified using 18 PCR cycles, purified using Agencourt AMPure XP SPRI beads (Beckman Coulter A63881) and size-selected on an agarose gel. DNA was extracted using the QiaQuick gel extraction kit (Qiagen) and its concentration determined using the KAPA Illumina SYBR Universal Lid Q Kit (KAPA Biosystems KK4824) and Bioanalyzer 2100 system (Agilent). SRS1146196 SAMN04235860 3 ChIP-Seq GENOMIC ChIP Illumina HiSeq 2500 SRX1428009 5 SRP065769 PRJNA298763 DNA from 4 IPs was pooled for each library generated with the NEB Next DNA Library Prep Master Mix (NEB E6040) according to manufacturer’s instructions. Libraries were amplified using 18 PCR cycles, purified using Agencourt AMPure XP SPRI beads (Beckman Coulter A63881) and size-selected on an agarose gel. DNA was extracted using the QiaQuick gel extraction kit (Qiagen) and its concentration determined using the KAPA Illumina SYBR Universal Lid Q Kit (KAPA Biosystems KK4824) and Bioanalyzer 2100 system (Agilent). SRS1146200 SAMN04235862 5 ChIP-Seq GENOMIC ChIP Illumina HiSeq 2500