SRP066676 PRJNA299562 Cancer hotspot panel sequencing in circulating tumour DNA DNA from plasma and matching tumour biopsy from cancer patients were sequenced using a 50-gene cancer hotspot panel, to determine whether the same mutations are detected in plasma DNA and tumour DNA from a given patient. Our eventual aim is to find out whether plasma DNA sequencing from a blood sample could be used for monitoring and in treatment decisions for cancer patients, which would be especially important when the biopsy procedure poses significant risk to the patient. Homo sapiens