SRX1495487 GSM1977538 SRP067667 SRS1218096 GSM1977538 RNA-Seq TRANSCRIPTOMIC cDNA LT-HSCs, were FACS sorted from primary recipients, 8 weeks after last PolyIC injection, directly into lysis buffer supplemented with RNase Inhibitor (Clontech). 3 biological replicates were generated from each genotype. Samples were prepared using the SMARTer™ Ultra Low RNA kit for Illumina Sequencing (Clontech) as previously described (Ramskold et al., 2012). Illumina HiSeq 2500 gds 301977538 GEO Accession GSM1977538 SRX1495488 GSM1977539 SRP067667 SRS1218095 GSM1977539 RNA-Seq TRANSCRIPTOMIC cDNA LT-HSCs, were FACS sorted from primary recipients, 8 weeks after last PolyIC injection, directly into lysis buffer supplemented with RNase Inhibitor (Clontech). 3 biological replicates were generated from each genotype. Samples were prepared using the SMARTer™ Ultra Low RNA kit for Illumina Sequencing (Clontech) as previously described (Ramskold et al., 2012). Illumina HiSeq 2500 gds 301977539 GEO Accession GSM1977539 SRX1495489 GSM1977540 SRP067667 SRS1218094 GSM1977540 RNA-Seq TRANSCRIPTOMIC cDNA LT-HSCs, were FACS sorted from primary recipients, 8 weeks after last PolyIC injection, directly into lysis buffer supplemented with RNase Inhibitor (Clontech). 3 biological replicates were generated from each genotype. Samples were prepared using the SMARTer™ Ultra Low RNA kit for Illumina Sequencing (Clontech) as previously described (Ramskold et al., 2012). Illumina HiSeq 2500 gds 301977540 GEO Accession GSM1977540 SRX1495490 GSM1977541 SRP067667 SRS1218093 GSM1977541 RNA-Seq TRANSCRIPTOMIC cDNA LT-HSCs, were FACS sorted from primary recipients, 8 weeks after last PolyIC injection, directly into lysis buffer supplemented with RNase Inhibitor (Clontech). 3 biological replicates were generated from each genotype. Samples were prepared using the SMARTer™ Ultra Low RNA kit for Illumina Sequencing (Clontech) as previously described (Ramskold et al., 2012). Illumina HiSeq 2500 gds 301977541 GEO Accession GSM1977541 SRX1495491 GSM1977542 SRP067667 SRS1218092 GSM1977542 RNA-Seq TRANSCRIPTOMIC cDNA LT-HSCs, were FACS sorted from primary recipients, 8 weeks after last PolyIC injection, directly into lysis buffer supplemented with RNase Inhibitor (Clontech). 3 biological replicates were generated from each genotype. Samples were prepared using the SMARTer™ Ultra Low RNA kit for Illumina Sequencing (Clontech) as previously described (Ramskold et al., 2012). Illumina HiSeq 2500 gds 301977542 GEO Accession GSM1977542 SRX1495492 GSM1977543 SRP067667 SRS1218091 GSM1977543 RNA-Seq TRANSCRIPTOMIC cDNA LT-HSCs, were FACS sorted from primary recipients, 8 weeks after last PolyIC injection, directly into lysis buffer supplemented with RNase Inhibitor (Clontech). 3 biological replicates were generated from each genotype. Samples were prepared using the SMARTer™ Ultra Low RNA kit for Illumina Sequencing (Clontech) as previously described (Ramskold et al., 2012). Illumina HiSeq 2500 gds 301977543 GEO Accession GSM1977543