SRS1443267 SAMN05004526 10116 Rattus norvegicus bioproject 284493 PRJNA284493 strain Wistar age 216 days sex male tissue Liver biomaterial_provider University of Paris-Saclay, Neuroscience Paris-Saclay Institute, Orsay (France) birth_date 12/2011 birth_location University of Paris-Saclay, Neuroscience Paris-Saclay Institute, Orsay (France) breeding_history standard breeding_method natural: Wistar virgin females of 8 weeks and males of 12 weeks were housed in collective cages for mating. Day 1 of pregnancy is identified by the presence of spermatozoa on vaginal frottis geo_loc_name France: Orsay growth_protocol Pregnant females and dams with their litters were housed in individual cages. They were fed ad libitum commercial high-fat diet (formula HF-235, Safe, Augy, France). The energy density of this diet was 4,397 kcal/kg with 15.5% from proteins, 48% from lipids, and 38.5% from carbohydrates. The size of the litters were standardized at day 1 to 10 pups. At weaning, progenies were fed ad libitum commercial control diet (formula 113, Safe, Augy, France). The energy density of the diet was 3,389 kcal/kg with 23% from proteins, 12% from lipids and 65% from carbohydrates. At day 139 and for 10 weeks, rats were fed ad libitum with maternal high-fat diet (formula HF-235, Safe, Augy, France). health_state good health BioSampleModel Model organism or animal