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  <STUDY center_name="GEO" alias="GSE85766" accession="SRP082317">
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      <PRIMARY_ID>SRP082317</PRIMARY_ID>
      <EXTERNAL_ID namespace="BioProject" label="primary">PRJNA339293</EXTERNAL_ID>
      <EXTERNAL_ID namespace="GEO">GSE85766</EXTERNAL_ID>
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      <STUDY_TITLE>Cellular model of colon cancer progression reveals signatures of mRNAs, miRNA, lncRNAs and epigenetic modifications associated with metastasis.</STUDY_TITLE>
      <STUDY_TYPE existing_study_type="Other"/>
      <STUDY_ABSTRACT>H3K4me3, H3K27me3, and H3K79me3 profiling of a cellular model of colorectal cancer progression, which is based on four defined derivates of a CRC cell line that resulted from EMT/MET transitions and phenotypically recapitulate the metastatic cascade: epithelial-like primary tumor, mesenchymal-like tumor cells growing in soft agar or as colonospheres, and mouse xenografts of the latter resulting in lung-metastasis comprised of epithelial-state cells. Overall design: H3K4me3, H3K27me3, and H3K79me3</STUDY_ABSTRACT>
      <CENTER_PROJECT_NAME>GSE85766</CENTER_PROJECT_NAME>
    </DESCRIPTOR>
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        <XREF_LINK>
          <DB>pubmed</DB>
          <ID>28130225</ID>
        </XREF_LINK>
      </STUDY_LINK>
    </STUDY_LINKS>
    <STUDY_ATTRIBUTES>
      <STUDY_ATTRIBUTE>
        <TAG>parent_bioproject</TAG>
        <VALUE>PRJNA339061</VALUE>
      </STUDY_ATTRIBUTE>
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