<?xml version="1.0" encoding="UTF-8"?>
<STUDY_SET xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <STUDY center_name="GEO" alias="GSE93610" accession="SRP096749">
    <IDENTIFIERS>
      <PRIMARY_ID>SRP096749</PRIMARY_ID>
      <EXTERNAL_ID namespace="BioProject" label="primary">PRJNA361293</EXTERNAL_ID>
      <EXTERNAL_ID namespace="GEO">GSE93610</EXTERNAL_ID>
    </IDENTIFIERS>
    <DESCRIPTOR>
      <STUDY_TITLE>Time-course expression data from HEK293?RAF1:ER cells stimulated with 4OHT and labelled with 4SU</STUDY_TITLE>
      <STUDY_TYPE existing_study_type="Transcriptome Analysis"/>
      <STUDY_ABSTRACT>We integrate experimental data and mathematical modelling to unveil how ERK signal duration is translated to mRNA dynamics. Overall design: HEK293 cells were transfected with an inducible form of RAF (?RAF1:ER), labelled with 4-thiouridine (4SU) one hour before harvesting and induced with tamoxifen (4OHT) for different periods of time (0h-8h).</STUDY_ABSTRACT>
      <CENTER_PROJECT_NAME>GSE93610</CENTER_PROJECT_NAME>
    </DESCRIPTOR>
    <STUDY_LINKS>
      <STUDY_LINK>
        <XREF_LINK>
          <DB>pubmed</DB>
          <ID>28468958</ID>
        </XREF_LINK>
      </STUDY_LINK>
    </STUDY_LINKS>
    <STUDY_ATTRIBUTES>
      <STUDY_ATTRIBUTE>
        <TAG>parent_bioproject</TAG>
        <VALUE>PRJNA361281</VALUE>
      </STUDY_ATTRIBUTE>
    </STUDY_ATTRIBUTES>
  </STUDY>
</STUDY_SET>
