SRX2564929 GSM2492380 SRP099896 SRS1981571 GSM2492380 OTHER GENOMIC other 4C was done from pools of 60-70 E9.5 embryos or 1-2x10^6 G4 cells per biological replicate. Embryos were minced, treated with collagenase type 2 and passed throw a 70 micrometers cell strainer, and ES cells were harvested and counted. Samples were crosslinked with 2% PFA, frozen with liquid nitrogen and stored at -80º for later processing. After lysis, chromatin was digested with DpnII (New England BioLabs) as primary enzyme and NlaIII (New England BioLabs) as secondary enzyme, and ligated with T4 DNA Ligase (Promega) was used for the two ligation steps. Circular ligated DNA was amplified using specific primers with the Illumina adaptor library included. Illumina HiSeq 2500 gds 302492380 GEO Accession GSM2492380 SRX2564930 GSM2492381 SRP099896 SRS1981572 GSM2492381 OTHER GENOMIC other 4C was done from pools of 60-70 E9.5 embryos or 1-2x10^6 G4 cells per biological replicate. Embryos were minced, treated with collagenase type 2 and passed throw a 70 micrometers cell strainer, and ES cells were harvested and counted. Samples were crosslinked with 2% PFA, frozen with liquid nitrogen and stored at -80º for later processing. After lysis, chromatin was digested with DpnII (New England BioLabs) as primary enzyme and NlaIII (New England BioLabs) as secondary enzyme, and ligated with T4 DNA Ligase (Promega) was used for the two ligation steps. Circular ligated DNA was amplified using specific primers with the Illumina adaptor library included. Illumina HiSeq 2500 gds 302492381 GEO Accession GSM2492381 SRX2564931 GSM2492382 SRP099896 SRS1981573 GSM2492382 OTHER GENOMIC other 4C was done from pools of 60-70 E9.5 embryos or 1-2x10^6 G4 cells per biological replicate. Embryos were minced, treated with collagenase type 2 and passed throw a 70 micrometers cell strainer, and ES cells were harvested and counted. Samples were crosslinked with 2% PFA, frozen with liquid nitrogen and stored at -80º for later processing. After lysis, chromatin was digested with DpnII (New England BioLabs) as primary enzyme and NlaIII (New England BioLabs) as secondary enzyme, and ligated with T4 DNA Ligase (Promega) was used for the two ligation steps. Circular ligated DNA was amplified using specific primers with the Illumina adaptor library included. Illumina HiSeq 2500 gds 302492382 GEO Accession GSM2492382 SRX2564932 GSM2492383 SRP099896 SRS1981574 GSM2492383 OTHER GENOMIC other 4C was done from pools of 60-70 E9.5 embryos or 1-2x10^6 G4 cells per biological replicate. Embryos were minced, treated with collagenase type 2 and passed throw a 70 micrometers cell strainer, and ES cells were harvested and counted. Samples were crosslinked with 2% PFA, frozen with liquid nitrogen and stored at -80º for later processing. After lysis, chromatin was digested with DpnII (New England BioLabs) as primary enzyme and NlaIII (New England BioLabs) as secondary enzyme, and ligated with T4 DNA Ligase (Promega) was used for the two ligation steps. Circular ligated DNA was amplified using specific primers with the Illumina adaptor library included. Illumina HiSeq 2500 gds 302492383 GEO Accession GSM2492383 SRX2564933 GSM2492384 SRP099896 SRS1981575 GSM2492384 OTHER GENOMIC other 4C was done from pools of 60-70 E9.5 embryos or 1-2x10^6 G4 cells per biological replicate. Embryos were minced, treated with collagenase type 2 and passed throw a 70 micrometers cell strainer, and ES cells were harvested and counted. Samples were crosslinked with 2% PFA, frozen with liquid nitrogen and stored at -80º for later processing. After lysis, chromatin was digested with DpnII (New England BioLabs) as primary enzyme and NlaIII (New England BioLabs) as secondary enzyme, and ligated with T4 DNA Ligase (Promega) was used for the two ligation steps. Circular ligated DNA was amplified using specific primers with the Illumina adaptor library included. Illumina HiSeq 2500 gds 302492384 GEO Accession GSM2492384 SRX2564934 GSM2492385 SRP099896 SRS1981576 GSM2492385 OTHER GENOMIC other 4C was done from pools of 60-70 E9.5 embryos or 1-2x10^6 G4 cells per biological replicate. Embryos were minced, treated with collagenase type 2 and passed throw a 70 micrometers cell strainer, and ES cells were harvested and counted. Samples were crosslinked with 2% PFA, frozen with liquid nitrogen and stored at -80º for later processing. After lysis, chromatin was digested with DpnII (New England BioLabs) as primary enzyme and NlaIII (New England BioLabs) as secondary enzyme, and ligated with T4 DNA Ligase (Promega) was used for the two ligation steps. Circular ligated DNA was amplified using specific primers with the Illumina adaptor library included. Illumina HiSeq 2500 gds 302492385 GEO Accession GSM2492385 SRX2564935 GSM2492386 SRP099896 SRS1981577 GSM2492386 OTHER GENOMIC other 4C was done from pools of 60-70 E9.5 embryos or 1-2x10^6 G4 cells per biological replicate. Embryos were minced, treated with collagenase type 2 and passed throw a 70 micrometers cell strainer, and ES cells were harvested and counted. Samples were crosslinked with 2% PFA, frozen with liquid nitrogen and stored at -80º for later processing. After lysis, chromatin was digested with DpnII (New England BioLabs) as primary enzyme and NlaIII (New England BioLabs) as secondary enzyme, and ligated with T4 DNA Ligase (Promega) was used for the two ligation steps. Circular ligated DNA was amplified using specific primers with the Illumina adaptor library included. Illumina HiSeq 2500 gds 302492386 GEO Accession GSM2492386 SRX2564936 GSM2492387 SRP099896 SRS1981578 GSM2492387 OTHER GENOMIC other 4C was done from pools of 60-70 E9.5 embryos or 1-2x10^6 G4 cells per biological replicate. Embryos were minced, treated with collagenase type 2 and passed throw a 70 micrometers cell strainer, and ES cells were harvested and counted. Samples were crosslinked with 2% PFA, frozen with liquid nitrogen and stored at -80º for later processing. After lysis, chromatin was digested with DpnII (New England BioLabs) as primary enzyme and NlaIII (New England BioLabs) as secondary enzyme, and ligated with T4 DNA Ligase (Promega) was used for the two ligation steps. Circular ligated DNA was amplified using specific primers with the Illumina adaptor library included. Illumina HiSeq 2500 gds 302492387 GEO Accession GSM2492387