SRP105435 PRJNA384616 Mosaic chromosomal aneuploidy detection by sequencing (MAD-seq) We present MAD-seq, which is a combination of a new sequencing-based assay and a novel analytical approach that allows low levels of mosaicism for chromosomal aneuploidy to be detected, assigned to a meiotic or mitotic origin, and quantified as a proportion of the cells in the sample. Homo sapiens MADSEQ R package http://bioconductor.org/packages/MADSEQ/