<?xml version="1.0" encoding="UTF-8"?>
<STUDY_SET xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <STUDY center_name="GEO" alias="GSE98974" accession="SRP107229">
    <IDENTIFIERS>
      <PRIMARY_ID>SRP107229</PRIMARY_ID>
      <EXTERNAL_ID namespace="BioProject" label="primary">PRJNA386927</EXTERNAL_ID>
      <EXTERNAL_ID namespace="GEO">GSE98974</EXTERNAL_ID>
    </IDENTIFIERS>
    <DESCRIPTOR>
      <STUDY_TITLE>Adult CNS Myelin Enhances Axonal Outgrowth From Neural Stem Cells</STUDY_TITLE>
      <STUDY_TYPE existing_study_type="Transcriptome Analysis"/>
      <STUDY_ABSTRACT>The growth of neural stem cells is strongly enhanced on myelin in vitro and in vivo. To identify the mechanisms associated with this phenome, we compared RNA expression from mouse E12 derived spinal cord cells on stimulation substrates (laminin and myelin) to permissive substrates (PDL). We identified Negr1 as mediator of the stimulatory effects of myelin. Overall design: Examination of transcripts in embryonic spinal cord cells stimulated by laminin and myelin substrates in vitro.</STUDY_ABSTRACT>
      <CENTER_PROJECT_NAME>GSE98974</CENTER_PROJECT_NAME>
    </DESCRIPTOR>
    <STUDY_LINKS>
      <STUDY_LINK>
        <XREF_LINK>
          <DB>pubmed</DB>
          <ID>29794059</ID>
        </XREF_LINK>
      </STUDY_LINK>
    </STUDY_LINKS>
  </STUDY>
</STUDY_SET>
