SRX2873432 GSM2644922 SRP108365 SRS2243554 GSM2644922 miRNA-Seq TRANSCRIPTOMIC size fractionation At the end of 11 week feeding period, the mice were fasted for 4 hours and then euthanized by CO2 inhalation. Epidedimal (VAT), inguinal (SAT) and interscapular (BAT) adipose tissues were harvested, and snap frozen immediately in liquid N2, followed by storage at -80°C. Frozen adipose tissue samples (SAT, BAT, and VAT- 3 samples per group) were homogenized in QIAzol® (QIAGEN, Redwood City, CA). Total RNA was isolated according to manufacturer’s protocol using RNeasy Mini Kit. Small RNA libraries were prepared using the Illumina small RNA protocol (Illumina, Inc., San Diego, CA) Illumina Genome Analyzer II gds 302644922 GSM2644922 GEO Accession GSM2644922 SRX2873433 GSM2644923 SRP108365 SRS2243555 GSM2644923 miRNA-Seq TRANSCRIPTOMIC size fractionation At the end of 11 week feeding period, the mice were fasted for 4 hours and then euthanized by CO2 inhalation. Epidedimal (VAT), inguinal (SAT) and interscapular (BAT) adipose tissues were harvested, and snap frozen immediately in liquid N2, followed by storage at -80°C. Frozen adipose tissue samples (SAT, BAT, and VAT- 3 samples per group) were homogenized in QIAzol® (QIAGEN, Redwood City, CA). Total RNA was isolated according to manufacturer’s protocol using RNeasy Mini Kit. Small RNA libraries were prepared using the Illumina small RNA protocol (Illumina, Inc., San Diego, CA) Illumina Genome Analyzer II gds 302644923 GSM2644923 GEO Accession GSM2644923 SRX2873434 GSM2644924 SRP108365 SRS2243556 GSM2644924 miRNA-Seq TRANSCRIPTOMIC size fractionation At the end of 11 week feeding period, the mice were fasted for 4 hours and then euthanized by CO2 inhalation. Epidedimal (VAT), inguinal (SAT) and interscapular (BAT) adipose tissues were harvested, and snap frozen immediately in liquid N2, followed by storage at -80°C. Frozen adipose tissue samples (SAT, BAT, and VAT- 3 samples per group) were homogenized in QIAzol® (QIAGEN, Redwood City, CA). Total RNA was isolated according to manufacturer’s protocol using RNeasy Mini Kit. Small RNA libraries were prepared using the Illumina small RNA protocol (Illumina, Inc., San Diego, CA) Illumina Genome Analyzer II gds 302644924 GSM2644924 GEO Accession GSM2644924 SRX2873435 GSM2644925 SRP108365 SRS2243557 GSM2644925 miRNA-Seq TRANSCRIPTOMIC size fractionation At the end of 11 week feeding period, the mice were fasted for 4 hours and then euthanized by CO2 inhalation. Epidedimal (VAT), inguinal (SAT) and interscapular (BAT) adipose tissues were harvested, and snap frozen immediately in liquid N2, followed by storage at -80°C. Frozen adipose tissue samples (SAT, BAT, and VAT- 3 samples per group) were homogenized in QIAzol® (QIAGEN, Redwood City, CA). Total RNA was isolated according to manufacturer’s protocol using RNeasy Mini Kit. Small RNA libraries were prepared using the Illumina small RNA protocol (Illumina, Inc., San Diego, CA) Illumina Genome Analyzer II gds 302644925 GSM2644925 GEO Accession GSM2644925 SRX2873436 GSM2644926 SRP108365 SRS2243558 GSM2644926 miRNA-Seq TRANSCRIPTOMIC size fractionation At the end of 11 week feeding period, the mice were fasted for 4 hours and then euthanized by CO2 inhalation. Epidedimal (VAT), inguinal (SAT) and interscapular (BAT) adipose tissues were harvested, and snap frozen immediately in liquid N2, followed by storage at -80°C. Frozen adipose tissue samples (SAT, BAT, and VAT- 3 samples per group) were homogenized in QIAzol® (QIAGEN, Redwood City, CA). Total RNA was isolated according to manufacturer’s protocol using RNeasy Mini Kit. Small RNA libraries were prepared using the Illumina small RNA protocol (Illumina, Inc., San Diego, CA) Illumina Genome Analyzer II gds 302644926 GSM2644926 GEO Accession GSM2644926 SRX2873437 GSM2644927 SRP108365 SRS2243559 GSM2644927 miRNA-Seq TRANSCRIPTOMIC size fractionation At the end of 11 week feeding period, the mice were fasted for 4 hours and then euthanized by CO2 inhalation. Epidedimal (VAT), inguinal (SAT) and interscapular (BAT) adipose tissues were harvested, and snap frozen immediately in liquid N2, followed by storage at -80°C. Frozen adipose tissue samples (SAT, BAT, and VAT- 3 samples per group) were homogenized in QIAzol® (QIAGEN, Redwood City, CA). Total RNA was isolated according to manufacturer’s protocol using RNeasy Mini Kit. Small RNA libraries were prepared using the Illumina small RNA protocol (Illumina, Inc., San Diego, CA) Illumina Genome Analyzer II gds 302644927 GSM2644927 GEO Accession GSM2644927