SRX2899901 GSM2656502 SRP108894 SRS2267146 GSM2656502 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA was extracted using the miRNeasy Mini Kit (Qiagen, Hilden, Germany). RNA-Seq was performed for 12 cell lines and conditions: DO4, MM415, AV1, AV4, AV5 parental cell lines; DO4 and MM415 cells after short-term (6 hours) treatment with GSK1120212; DO4-RM, MM415-RM, AV1-RM, AV4-RM, and AV5 ChrExp. cDNA sequencing libraries were prepared using the Illumina TruSeq Total RNA Sample kit, which uses Ribo-Zero to deplete rRNA, leaving ncRNAs intact. Standard Immumina protocols were used. Paired-end, 101-bp sequencing was performed by Centrillion Biosciencies Inc. (CA, US) on an Illumina HiSeq 2000. Sequence reads are aligned to the human genome (hg19) using TopHat. Illumina HiSeq 2000 gds 302656502 GSM2656502 GEO Accession GSM2656502 SRX2899902 GSM2656503 SRP108894 SRS2267148 GSM2656503 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA was extracted using the miRNeasy Mini Kit (Qiagen, Hilden, Germany). RNA-Seq was performed for 12 cell lines and conditions: DO4, MM415, AV1, AV4, AV5 parental cell lines; DO4 and MM415 cells after short-term (6 hours) treatment with GSK1120212; DO4-RM, MM415-RM, AV1-RM, AV4-RM, and AV5 ChrExp. cDNA sequencing libraries were prepared using the Illumina TruSeq Total RNA Sample kit, which uses Ribo-Zero to deplete rRNA, leaving ncRNAs intact. Standard Immumina protocols were used. Paired-end, 101-bp sequencing was performed by Centrillion Biosciencies Inc. (CA, US) on an Illumina HiSeq 2000. Sequence reads are aligned to the human genome (hg19) using TopHat. Illumina HiSeq 2000 gds 302656503 GSM2656503 GEO Accession GSM2656503 SRX2899903 GSM2656504 SRP108894 SRS2267147 GSM2656504 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA was extracted using the miRNeasy Mini Kit (Qiagen, Hilden, Germany). RNA-Seq was performed for 12 cell lines and conditions: DO4, MM415, AV1, AV4, AV5 parental cell lines; DO4 and MM415 cells after short-term (6 hours) treatment with GSK1120212; DO4-RM, MM415-RM, AV1-RM, AV4-RM, and AV5 ChrExp. cDNA sequencing libraries were prepared using the Illumina TruSeq Total RNA Sample kit, which uses Ribo-Zero to deplete rRNA, leaving ncRNAs intact. Standard Immumina protocols were used. Paired-end, 101-bp sequencing was performed by Centrillion Biosciencies Inc. (CA, US) on an Illumina HiSeq 2000. Sequence reads are aligned to the human genome (hg19) using TopHat. Illumina HiSeq 2000 gds 302656504 GSM2656504 GEO Accession GSM2656504 SRX2899904 GSM2656505 SRP108894 SRS2267149 GSM2656505 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA was extracted using the miRNeasy Mini Kit (Qiagen, Hilden, Germany). RNA-Seq was performed for 12 cell lines and conditions: DO4, MM415, AV1, AV4, AV5 parental cell lines; DO4 and MM415 cells after short-term (6 hours) treatment with GSK1120212; DO4-RM, MM415-RM, AV1-RM, AV4-RM, and AV5 ChrExp. cDNA sequencing libraries were prepared using the Illumina TruSeq Total RNA Sample kit, which uses Ribo-Zero to deplete rRNA, leaving ncRNAs intact. Standard Immumina protocols were used. Paired-end, 101-bp sequencing was performed by Centrillion Biosciencies Inc. (CA, US) on an Illumina HiSeq 2000. Sequence reads are aligned to the human genome (hg19) using TopHat. Illumina HiSeq 2000 gds 302656505 GSM2656505 GEO Accession GSM2656505 SRX2899905 GSM2656506 SRP108894 SRS2267150 GSM2656506 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA was extracted using the miRNeasy Mini Kit (Qiagen, Hilden, Germany). RNA-Seq was performed for 12 cell lines and conditions: DO4, MM415, AV1, AV4, AV5 parental cell lines; DO4 and MM415 cells after short-term (6 hours) treatment with GSK1120212; DO4-RM, MM415-RM, AV1-RM, AV4-RM, and AV5 ChrExp. cDNA sequencing libraries were prepared using the Illumina TruSeq Total RNA Sample kit, which uses Ribo-Zero to deplete rRNA, leaving ncRNAs intact. Standard Immumina protocols were used. Paired-end, 101-bp sequencing was performed by Centrillion Biosciencies Inc. (CA, US) on an Illumina HiSeq 2000. Sequence reads are aligned to the human genome (hg19) using TopHat. Illumina HiSeq 2000 gds 302656506 GSM2656506 GEO Accession GSM2656506 SRX2899906 GSM2656507 SRP108894 SRS2267151 GSM2656507 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA was extracted using the miRNeasy Mini Kit (Qiagen, Hilden, Germany). RNA-Seq was performed for 12 cell lines and conditions: DO4, MM415, AV1, AV4, AV5 parental cell lines; DO4 and MM415 cells after short-term (6 hours) treatment with GSK1120212; DO4-RM, MM415-RM, AV1-RM, AV4-RM, and AV5 ChrExp. cDNA sequencing libraries were prepared using the Illumina TruSeq Total RNA Sample kit, which uses Ribo-Zero to deplete rRNA, leaving ncRNAs intact. Standard Immumina protocols were used. Paired-end, 101-bp sequencing was performed by Centrillion Biosciencies Inc. (CA, US) on an Illumina HiSeq 2000. Sequence reads are aligned to the human genome (hg19) using TopHat. Illumina HiSeq 2000 gds 302656507 GSM2656507 GEO Accession GSM2656507 SRX2899907 GSM2656508 SRP108894 SRS2267152 GSM2656508 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA was extracted using the miRNeasy Mini Kit (Qiagen, Hilden, Germany). RNA-Seq was performed for 12 cell lines and conditions: DO4, MM415, AV1, AV4, AV5 parental cell lines; DO4 and MM415 cells after short-term (6 hours) treatment with GSK1120212; DO4-RM, MM415-RM, AV1-RM, AV4-RM, and AV5 ChrExp. cDNA sequencing libraries were prepared using the Illumina TruSeq Total RNA Sample kit, which uses Ribo-Zero to deplete rRNA, leaving ncRNAs intact. Standard Immumina protocols were used. Paired-end, 101-bp sequencing was performed by Centrillion Biosciencies Inc. (CA, US) on an Illumina HiSeq 2000. Sequence reads are aligned to the human genome (hg19) using TopHat. Illumina HiSeq 2000 gds 302656508 GSM2656508 GEO Accession GSM2656508 SRX2899908 GSM2656509 SRP108894 SRS2267164 GSM2656509 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA was extracted using the miRNeasy Mini Kit (Qiagen, Hilden, Germany). RNA-Seq was performed for 12 cell lines and conditions: DO4, MM415, AV1, AV4, AV5 parental cell lines; DO4 and MM415 cells after short-term (6 hours) treatment with GSK1120212; DO4-RM, MM415-RM, AV1-RM, AV4-RM, and AV5 ChrExp. cDNA sequencing libraries were prepared using the Illumina TruSeq Total RNA Sample kit, which uses Ribo-Zero to deplete rRNA, leaving ncRNAs intact. Standard Immumina protocols were used. Paired-end, 101-bp sequencing was performed by Centrillion Biosciencies Inc. (CA, US) on an Illumina HiSeq 2000. Sequence reads are aligned to the human genome (hg19) using TopHat. Illumina HiSeq 2000 gds 302656509 GSM2656509 GEO Accession GSM2656509 SRX2899909 GSM2656510 SRP108894 SRS2267153 GSM2656510 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA was extracted using the miRNeasy Mini Kit (Qiagen, Hilden, Germany). RNA-Seq was performed for 12 cell lines and conditions: DO4, MM415, AV1, AV4, AV5 parental cell lines; DO4 and MM415 cells after short-term (6 hours) treatment with GSK1120212; DO4-RM, MM415-RM, AV1-RM, AV4-RM, and AV5 ChrExp. cDNA sequencing libraries were prepared using the Illumina TruSeq Total RNA Sample kit, which uses Ribo-Zero to deplete rRNA, leaving ncRNAs intact. Standard Immumina protocols were used. Paired-end, 101-bp sequencing was performed by Centrillion Biosciencies Inc. (CA, US) on an Illumina HiSeq 2000. Sequence reads are aligned to the human genome (hg19) using TopHat. Illumina HiSeq 2000 gds 302656510 GSM2656510 GEO Accession GSM2656510 SRX2899910 GSM2656511 SRP108894 SRS2267166 GSM2656511 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA was extracted using the miRNeasy Mini Kit (Qiagen, Hilden, Germany). RNA-Seq was performed for 12 cell lines and conditions: DO4, MM415, AV1, AV4, AV5 parental cell lines; DO4 and MM415 cells after short-term (6 hours) treatment with GSK1120212; DO4-RM, MM415-RM, AV1-RM, AV4-RM, and AV5 ChrExp. cDNA sequencing libraries were prepared using the Illumina TruSeq Total RNA Sample kit, which uses Ribo-Zero to deplete rRNA, leaving ncRNAs intact. Standard Immumina protocols were used. Paired-end, 101-bp sequencing was performed by Centrillion Biosciencies Inc. (CA, US) on an Illumina HiSeq 2000. Sequence reads are aligned to the human genome (hg19) using TopHat. Illumina HiSeq 2000 gds 302656511 GSM2656511 GEO Accession GSM2656511 SRX2899911 GSM2656512 SRP108894 SRS2267154 GSM2656512 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA was extracted using the miRNeasy Mini Kit (Qiagen, Hilden, Germany). RNA-Seq was performed for 12 cell lines and conditions: DO4, MM415, AV1, AV4, AV5 parental cell lines; DO4 and MM415 cells after short-term (6 hours) treatment with GSK1120212; DO4-RM, MM415-RM, AV1-RM, AV4-RM, and AV5 ChrExp. cDNA sequencing libraries were prepared using the Illumina TruSeq Total RNA Sample kit, which uses Ribo-Zero to deplete rRNA, leaving ncRNAs intact. Standard Immumina protocols were used. Paired-end, 101-bp sequencing was performed by Centrillion Biosciencies Inc. (CA, US) on an Illumina HiSeq 2000. Sequence reads are aligned to the human genome (hg19) using TopHat. Illumina HiSeq 2000 gds 302656512 GSM2656512 GEO Accession GSM2656512 SRX2899912 GSM2656513 SRP108894 SRS2267157 GSM2656513 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA was extracted using the miRNeasy Mini Kit (Qiagen, Hilden, Germany). RNA-Seq was performed for 12 cell lines and conditions: DO4, MM415, AV1, AV4, AV5 parental cell lines; DO4 and MM415 cells after short-term (6 hours) treatment with GSK1120212; DO4-RM, MM415-RM, AV1-RM, AV4-RM, and AV5 ChrExp. cDNA sequencing libraries were prepared using the Illumina TruSeq Total RNA Sample kit, which uses Ribo-Zero to deplete rRNA, leaving ncRNAs intact. Standard Immumina protocols were used. Paired-end, 101-bp sequencing was performed by Centrillion Biosciencies Inc. (CA, US) on an Illumina HiSeq 2000. Sequence reads are aligned to the human genome (hg19) using TopHat. Illumina HiSeq 2000 gds 302656513 GSM2656513 GEO Accession GSM2656513