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<EXPERIMENT_SET xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <EXPERIMENT accession="SRX2900163" alias="E2male">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX2900163</PRIMARY_ID>
      <SUBMITTER_ID namespace="SUB2757288">E2male</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Adult_Exposed_Male_2</TITLE>
    <STUDY_REF accession="SRP108901">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP108901</PRIMARY_ID>
        <EXTERNAL_ID namespace="BioProject">PRJNA389649</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>Libraries were generated from 250 ng of total RNA using the TruSeq stranded mRNA Sample Preparation Kit (Illumina), as per the manufacturer’s recommendations. Libraries were quantified using the Quant-iT™ PicoGreen® dsDNA Assay Kit (Life Technologies) and the Kapa Illumina GA with Revised Primers-SYBR Fast Universal kit (Kapa Biosystems). Average size fragment was determined using a LabChip GX (PerkinElmer) instrument. The libraries were normalized, denatured in 0.05N NaOH and then were diluted to 8pM using HT1 buffer. The clustering was done on a Illumina cBot and the flowcell was ran on a HiSeq 2000 for 2x100 cycles following the manufacturer's instructions. A phiX library was used as a control and mixed with libraries at 1% level. The Illumina control software was HCS 2.2.58, the real-time analysis program was RTA v. 1.18.63. Program bcl2fastq v1.8.4 was then used to demultiplex samples and generate fastq reads.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS2267407">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS2267407</PRIMARY_ID>
          <EXTERNAL_ID namespace="BioSample">SAMN07204408</EXTERNAL_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
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        <LIBRARY_NAME>E2male</LIBRARY_NAME>
        <LIBRARY_STRATEGY>RNA-Seq</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>TRANSCRIPTOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RT-PCR</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina HiSeq 2000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX2900164" alias="E1female">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX2900164</PRIMARY_ID>
      <SUBMITTER_ID namespace="SUB2757288">E1female</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Adult_Exposed_Female_1</TITLE>
    <STUDY_REF accession="SRP108901">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP108901</PRIMARY_ID>
        <EXTERNAL_ID namespace="BioProject">PRJNA389649</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>Libraries were generated from 250 ng of total RNA using the TruSeq stranded mRNA Sample Preparation Kit (Illumina), as per the manufacturer’s recommendations. Libraries were quantified using the Quant-iT™ PicoGreen® dsDNA Assay Kit (Life Technologies) and the Kapa Illumina GA with Revised Primers-SYBR Fast Universal kit (Kapa Biosystems). Average size fragment was determined using a LabChip GX (PerkinElmer) instrument. The libraries were normalized, denatured in 0.05N NaOH and then were diluted to 8pM using HT1 buffer. The clustering was done on a Illumina cBot and the flowcell was ran on a HiSeq 2000 for 2x100 cycles following the manufacturer's instructions. A phiX library was used as a control and mixed with libraries at 1% level. The Illumina control software was HCS 2.2.58, the real-time analysis program was RTA v. 1.18.63. Program bcl2fastq v1.8.4 was then used to demultiplex samples and generate fastq reads.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS2267408">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS2267408</PRIMARY_ID>
          <EXTERNAL_ID namespace="BioSample">SAMN07204410</EXTERNAL_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>E1female</LIBRARY_NAME>
        <LIBRARY_STRATEGY>RNA-Seq</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>TRANSCRIPTOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RT-PCR</LIBRARY_SELECTION>
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          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina HiSeq 2000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX2900165" alias="E2female">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX2900165</PRIMARY_ID>
      <SUBMITTER_ID namespace="SUB2757288">E2female</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Adult_Exposed_Female_2</TITLE>
    <STUDY_REF accession="SRP108901">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP108901</PRIMARY_ID>
        <EXTERNAL_ID namespace="BioProject">PRJNA389649</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>Libraries were generated from 250 ng of total RNA using the TruSeq stranded mRNA Sample Preparation Kit (Illumina), as per the manufacturer’s recommendations. Libraries were quantified using the Quant-iT™ PicoGreen® dsDNA Assay Kit (Life Technologies) and the Kapa Illumina GA with Revised Primers-SYBR Fast Universal kit (Kapa Biosystems). Average size fragment was determined using a LabChip GX (PerkinElmer) instrument. The libraries were normalized, denatured in 0.05N NaOH and then were diluted to 8pM using HT1 buffer. The clustering was done on a Illumina cBot and the flowcell was ran on a HiSeq 2000 for 2x100 cycles following the manufacturer's instructions. A phiX library was used as a control and mixed with libraries at 1% level. The Illumina control software was HCS 2.2.58, the real-time analysis program was RTA v. 1.18.63. Program bcl2fastq v1.8.4 was then used to demultiplex samples and generate fastq reads.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS2267409">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS2267409</PRIMARY_ID>
          <EXTERNAL_ID namespace="BioSample">SAMN07204411</EXTERNAL_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>E2female</LIBRARY_NAME>
        <LIBRARY_STRATEGY>RNA-Seq</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>TRANSCRIPTOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RT-PCR</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina HiSeq 2000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX2900166" alias="C1male">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX2900166</PRIMARY_ID>
      <SUBMITTER_ID namespace="SUB2757288">C1male</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Adult_Control_Male_1</TITLE>
    <STUDY_REF accession="SRP108901">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP108901</PRIMARY_ID>
        <EXTERNAL_ID namespace="BioProject">PRJNA389649</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>Libraries were generated from 250 ng of total RNA using the TruSeq stranded mRNA Sample Preparation Kit (Illumina), as per the manufacturer’s recommendations. Libraries were quantified using the Quant-iT™ PicoGreen® dsDNA Assay Kit (Life Technologies) and the Kapa Illumina GA with Revised Primers-SYBR Fast Universal kit (Kapa Biosystems). Average size fragment was determined using a LabChip GX (PerkinElmer) instrument. The libraries were normalized, denatured in 0.05N NaOH and then were diluted to 8pM using HT1 buffer. The clustering was done on a Illumina cBot and the flowcell was ran on a HiSeq 2000 for 2x100 cycles following the manufacturer's instructions. A phiX library was used as a control and mixed with libraries at 1% level. The Illumina control software was HCS 2.2.58, the real-time analysis program was RTA v. 1.18.63. Program bcl2fastq v1.8.4 was then used to demultiplex samples and generate fastq reads.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS2267410">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS2267410</PRIMARY_ID>
          <EXTERNAL_ID namespace="BioSample">SAMN07204400</EXTERNAL_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>C1male</LIBRARY_NAME>
        <LIBRARY_STRATEGY>RNA-Seq</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>TRANSCRIPTOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RT-PCR</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina HiSeq 2000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX2900167" alias="C2male">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX2900167</PRIMARY_ID>
      <SUBMITTER_ID namespace="SUB2757288">C2male</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Adult_Control_Male_2</TITLE>
    <STUDY_REF accession="SRP108901">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP108901</PRIMARY_ID>
        <EXTERNAL_ID namespace="BioProject">PRJNA389649</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>Libraries were generated from 250 ng of total RNA using the TruSeq stranded mRNA Sample Preparation Kit (Illumina), as per the manufacturer’s recommendations. Libraries were quantified using the Quant-iT™ PicoGreen® dsDNA Assay Kit (Life Technologies) and the Kapa Illumina GA with Revised Primers-SYBR Fast Universal kit (Kapa Biosystems). Average size fragment was determined using a LabChip GX (PerkinElmer) instrument. The libraries were normalized, denatured in 0.05N NaOH and then were diluted to 8pM using HT1 buffer. The clustering was done on a Illumina cBot and the flowcell was ran on a HiSeq 2000 for 2x100 cycles following the manufacturer's instructions. A phiX library was used as a control and mixed with libraries at 1% level. The Illumina control software was HCS 2.2.58, the real-time analysis program was RTA v. 1.18.63. Program bcl2fastq v1.8.4 was then used to demultiplex samples and generate fastq reads.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS2267411">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS2267411</PRIMARY_ID>
          <EXTERNAL_ID namespace="BioSample">SAMN07204401</EXTERNAL_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>C2male</LIBRARY_NAME>
        <LIBRARY_STRATEGY>RNA-Seq</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>TRANSCRIPTOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RT-PCR</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina HiSeq 2000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX2900168" alias="C1female">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX2900168</PRIMARY_ID>
      <SUBMITTER_ID namespace="SUB2757288">C1female</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Adult_Control_Female_1</TITLE>
    <STUDY_REF accession="SRP108901">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP108901</PRIMARY_ID>
        <EXTERNAL_ID namespace="BioProject">PRJNA389649</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>Libraries were generated from 250 ng of total RNA using the TruSeq stranded mRNA Sample Preparation Kit (Illumina), as per the manufacturer’s recommendations. Libraries were quantified using the Quant-iT™ PicoGreen® dsDNA Assay Kit (Life Technologies) and the Kapa Illumina GA with Revised Primers-SYBR Fast Universal kit (Kapa Biosystems). Average size fragment was determined using a LabChip GX (PerkinElmer) instrument. The libraries were normalized, denatured in 0.05N NaOH and then were diluted to 8pM using HT1 buffer. The clustering was done on a Illumina cBot and the flowcell was ran on a HiSeq 2000 for 2x100 cycles following the manufacturer's instructions. A phiX library was used as a control and mixed with libraries at 1% level. The Illumina control software was HCS 2.2.58, the real-time analysis program was RTA v. 1.18.63. Program bcl2fastq v1.8.4 was then used to demultiplex samples and generate fastq reads.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS2267412">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS2267412</PRIMARY_ID>
          <EXTERNAL_ID namespace="BioSample">SAMN07204403</EXTERNAL_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>C1female</LIBRARY_NAME>
        <LIBRARY_STRATEGY>RNA-Seq</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>TRANSCRIPTOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RT-PCR</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina HiSeq 2000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
  </EXPERIMENT>
  <EXPERIMENT accession="SRX2900169" alias="E1male">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX2900169</PRIMARY_ID>
      <SUBMITTER_ID namespace="SUB2757288">E1male</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>Adult_Exposed_Male_1</TITLE>
    <STUDY_REF accession="SRP108901">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP108901</PRIMARY_ID>
        <EXTERNAL_ID namespace="BioProject">PRJNA389649</EXTERNAL_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION>Libraries were generated from 250 ng of total RNA using the TruSeq stranded mRNA Sample Preparation Kit (Illumina), as per the manufacturer’s recommendations. Libraries were quantified using the Quant-iT™ PicoGreen® dsDNA Assay Kit (Life Technologies) and the Kapa Illumina GA with Revised Primers-SYBR Fast Universal kit (Kapa Biosystems). Average size fragment was determined using a LabChip GX (PerkinElmer) instrument. The libraries were normalized, denatured in 0.05N NaOH and then were diluted to 8pM using HT1 buffer. The clustering was done on a Illumina cBot and the flowcell was ran on a HiSeq 2000 for 2x100 cycles following the manufacturer's instructions. A phiX library was used as a control and mixed with libraries at 1% level. The Illumina control software was HCS 2.2.58, the real-time analysis program was RTA v. 1.18.63. Program bcl2fastq v1.8.4 was then used to demultiplex samples and generate fastq reads.</DESIGN_DESCRIPTION>
      <SAMPLE_DESCRIPTOR accession="SRS2267413">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS2267413</PRIMARY_ID>
          <EXTERNAL_ID namespace="BioSample">SAMN07204406</EXTERNAL_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_NAME>E1male</LIBRARY_NAME>
        <LIBRARY_STRATEGY>RNA-Seq</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>TRANSCRIPTOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>RT-PCR</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>Illumina HiSeq 2000</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
  </EXPERIMENT>
</EXPERIMENT_SET>
