Het(Q175)_Striatum_Male_CHDI-00390576_30mg/kg

SRS2528161 SAMN07675832 GSM2788673 Het(Q175)_Striatum_Male_CHDI-00390576_30mg/kg_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Striatum, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Striatum Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Striatum SRS2528173 SAMN07675820 GSM2788685 Het(Q175)_Striatum_Male_CHDI-00390576_30mg/kg_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Striatum, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Striatum Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Striatum SRS2528160 SAMN07675833 GSM2788672 WT_Striatum_Male_Vehicle_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Striatum, Vehicle background strain C57BL/6J genotype Wild Type tissue Striatum Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Striatum SRS2528175 SAMN07675818 GSM2788687 Het(Q175)_Striatum_Female_Vehicle_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Striatum, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Striatum Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Striatum SRS2528159 SAMN07675834 GSM2788671 Het(Q175)_Striatum_Male_CHDI-00390576_100mg/kg_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Striatum, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Striatum Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Striatum SRS2528177 SAMN07675816 GSM2788689 Het(Q175)_Striatum_Male_Vehicle_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Striatum, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Striatum Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Striatum SRS2528158 SAMN07675836 GSM2788669 Het(Q175)_Striatum_Male_Vehicle_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Striatum, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Striatum Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Striatum SRS2528179 SAMN07675876 GSM2788691 WT_Striatum_Male_Vehicle_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Striatum, Vehicle background strain C57BL/6J genotype Wild Type tissue Striatum Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Striatum SRS2528157 SAMN07675835 GSM2788670 Het(Q175)_Striatum_Female_CHDI-00390576_100mg/kg_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Striatum, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Striatum Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Striatum SRS2528181 SAMN07675874 GSM2788693 Het(Q175)_Cortex_Female_CHDI-00390576_30mg/kg_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Cortex, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Cortex Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Cortex SRS2528156 SAMN07675838 GSM2788667 Het(Q175)_Striatum_Male_Vehicle_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Striatum, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Striatum Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Striatum SRS2528183 SAMN07675872 GSM2788695 WT_Cortex_Female_Vehicle_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Cortex, Vehicle background strain C57BL/6J genotype Wild Type tissue Cortex Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Cortex SRS2528155 SAMN07675837 GSM2788668 Het(Q175)_Striatum_Male_CHDI-00390576_30mg/kg_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Striatum, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Striatum Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Striatum SRS2528185 SAMN07675870 GSM2788697 Het(Q175)_Cortex_Male_Vehicle_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Cortex, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Cortex Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Cortex SRS2528154 SAMN07675839 GSM2788666 Het(Q175)_Striatum_Female_CHDI-00390576_30mg/kg_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Striatum, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Striatum Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Striatum SRS2528187 SAMN07675867 GSM2788700 Het(Q175)_Cortex_Male_CHDI-00390576_100mg/kg_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Cortex, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Cortex Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Cortex SRS2528153 SAMN07675840 GSM2788665 Het(Q175)_Striatum_Female_CHDI-00390576_100mg/kg_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Striatum, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Striatum Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Striatum SRS2528189 SAMN07675866 GSM2788701 Het(Q175)_Cortex_Female_CHDI-00390576_100mg/kg_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Cortex, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Cortex Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Cortex SRS2528152 SAMN07675842 GSM2788663 Het(Q175)_Striatum_Female_CHDI-00390576_30mg/kg_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Striatum, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Striatum Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Striatum SRS2528191 SAMN07675864 GSM2788703 Het(Q175)_Cortex_Male_Vehicle_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Cortex, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Cortex Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Cortex SRS2528151 SAMN07675841 GSM2788664 WT_Striatum_Female_Vehicle_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Striatum, Vehicle background strain C57BL/6J genotype Wild Type tissue Striatum Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Striatum SRS2528193 SAMN07675862 GSM2788705 Het(Q175)_Cortex_Female_CHDI-00390576_30mg/kg_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Cortex, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Cortex Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Cortex SRS2528150 SAMN07675843 GSM2788662 Het(Q175)_Striatum_Male_Vehicle_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Striatum, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Striatum Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Striatum SRS2528195 SAMN07675860 GSM2788707 Het(Q175)_Cortex_Male_CHDI-00390576_100mg/kg_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Cortex, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Cortex Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Cortex SRS2528149 SAMN07675844 GSM2788661 Het(Q175)_Striatum_Female_Vehicle_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Striatum, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Striatum Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Striatum SRS2528197 SAMN07675858 GSM2788709 WT_Cortex_Male_Vehicle_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Cortex, Vehicle background strain C57BL/6J genotype Wild Type tissue Cortex Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Cortex SRS2528148 SAMN07675845 GSM2788660 WT_Striatum_Male_Vehicle_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Striatum, Vehicle background strain C57BL/6J genotype Wild Type tissue Striatum Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Striatum SRS2528199 SAMN07675856 GSM2788711 Het(Q175)_Cortex_Male_CHDI-00390576_100mg/kg_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Cortex, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Cortex Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Cortex SRS2528172 SAMN07675821 GSM2788684 WT_Striatum_Female_Vehicle_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Striatum, Vehicle background strain C57BL/6J genotype Wild Type tissue Striatum Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Striatum SRS2528201 SAMN07675854 GSM2788713 Het(Q175)_Cortex_Female_CHDI-00390576_100mg/kg_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Cortex, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Cortex Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Cortex SRS2528171 SAMN07675822 GSM2788683 Het(Q175)_Striatum_Male_CHDI-00390576_100mg/kg_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Striatum, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Striatum Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Striatum SRS2528203 SAMN07675924 GSM2788715 Het(Q175)_Cortex_Female_CHDI-00390576_100mg/kg_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Cortex, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Cortex Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Cortex SRS2528170 SAMN07675828 GSM2788682 Het(Q175)_Striatum_Female_CHDI-00390576_30mg/kg_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Striatum, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Striatum Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Striatum SRS2528205 SAMN07675921 GSM2788718 Het(Q175)_Cortex_Female_CHDI-00390576_30mg/kg_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Cortex, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Cortex Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Cortex SRS2528169 SAMN07675829 GSM2788681 Het(Q175)_Striatum_Female_CHDI-00390576_100mg/kg_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Striatum, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Striatum Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Striatum SRS2528207 SAMN07675920 GSM2788719 Het(Q175)_Cortex_Female_Vehicle_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Cortex, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Cortex Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Cortex SRS2528168 SAMN07675823 GSM2788680 Het(Q175)_Striatum_Female_CHDI-00390576_30mg/kg_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Striatum, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Striatum Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Striatum SRS2528209 SAMN07675814 GSM2788721 Het(Q175)_Cortex_Female_Vehicle_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Cortex, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Cortex Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Cortex SRS2528167 SAMN07675824 GSM2788679 WT_Striatum_Female_Vehicle_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Striatum, Vehicle background strain C57BL/6J genotype Wild Type tissue Striatum Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Striatum SRS2528211 SAMN07675812 GSM2788723 WT_Cortex_Male_Vehicle_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Cortex, Vehicle background strain C57BL/6J genotype Wild Type tissue Cortex Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Cortex SRS2528166 SAMN07675825 GSM2788678 Het(Q175)_Striatum_Male_CHDI-00390576_100mg/kg_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Striatum, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Striatum Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Striatum SRS2528213 SAMN07675810 GSM2788725 Het(Q175)_Tibialis_Male_CHDI-00390576_30mg/kg_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Tibialis, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Tibialis Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Tibialis SRS2528165 SAMN07675826 GSM2788677 WT_Striatum_Male_Vehicle_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Striatum, Vehicle background strain C57BL/6J genotype Wild Type tissue Striatum Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Striatum SRS2528215 SAMN07675808 GSM2788727 Het(Q175)_Tibialis_Female_Vehicle_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Tibialis, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Tibialis Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Tibialis SRS2528164 SAMN07675827 GSM2788676 WT_Striatum_Female_Vehicle_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Striatum, Vehicle background strain C57BL/6J genotype Wild Type tissue Striatum Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Striatum SRS2528217 SAMN07675806 GSM2788729 Het(Q175)_Tibialis_Male_Vehicle_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Tibialis, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Tibialis Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Tibialis SRS2528163 SAMN07675830 GSM2788675 Het(Q175)_Striatum_Male_CHDI-00390576_100mg/kg_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Striatum, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Striatum Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Striatum SRS2528219 SAMN07675804 GSM2788731 Het(Q175)_Tibialis_Male_CHDI-00390576_100mg/kg_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Tibialis, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Tibialis Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Tibialis SRS2528162 SAMN07675831 GSM2788674 Het(Q175)_Striatum_Female_Vehicle_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Striatum, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Striatum Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Striatum SRS2528221 SAMN07675802 GSM2788733 WT_Tibialis_Male_Vehicle_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Tibialis, Vehicle background strain C57BL/6J genotype Wild Type tissue Tibialis Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Tibialis SRS2528174 SAMN07675819 GSM2788686 Het(Q175)_Striatum_Female_Vehicle_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Striatum, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Striatum Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Striatum SRS2528223 SAMN07675800 GSM2788735 Het(Q175)_Tibialis_Female_CHDI-00390576_100mg/kg_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Tibialis, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Tibialis Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Tibialis SRS2528176 SAMN07675817 GSM2788688 Het(Q175)_Striatum_Male_CHDI-00390576_30mg/kg_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Striatum, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Striatum Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Striatum SRS2528225 SAMN07675798 GSM2788737 Het(Q175)_Tibialis_Female_CHDI-00390576_100mg/kg_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Tibialis, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Tibialis Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Tibialis SRS2528178 SAMN07675877 GSM2788690 Het(Q175)_Striatum_Female_CHDI-00390576_100mg/kg_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Striatum, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Striatum Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Striatum SRS2528227 SAMN07675796 GSM2788739 Het(Q175)_Tibialis_Female_CHDI-00390576_30mg/kg_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Tibialis, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Tibialis Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Tibialis SRS2528180 SAMN07675875 GSM2788692 Het(Q175)_Cortex_Female_CHDI-00390576_100mg/kg_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Cortex, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Cortex Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Cortex SRS2528229 SAMN07675794 GSM2788741 WT_Tibialis_Male_Vehicle_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Tibialis, Vehicle background strain C57BL/6J genotype Wild Type tissue Tibialis Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Tibialis SRS2528182 SAMN07675873 GSM2788694 WT_Cortex_Female_Vehicle_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Cortex, Vehicle background strain C57BL/6J genotype Wild Type tissue Cortex Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Cortex SRS2528231 SAMN07675792 GSM2788743 Het(Q175)_Tibialis_Male_CHDI-00390576_30mg/kg_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Tibialis, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Tibialis Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Tibialis SRS2528184 SAMN07675871 GSM2788696 Het(Q175)_Cortex_Male_CHDI-00390576_30mg/kg_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Cortex, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Cortex Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Cortex SRS2528233 SAMN07675790 GSM2788745 Het(Q175)_Tibialis_Male_Vehicle_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Tibialis, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Tibialis Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Tibialis SRS2528186 SAMN07675869 GSM2788698 WT_Cortex_Female_Vehicle_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Cortex, Vehicle background strain C57BL/6J genotype Wild Type tissue Cortex Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Cortex SRS2528235 SAMN07675788 GSM2788747 Het(Q175)_Tibialis_Female_CHDI-00390576_30mg/kg_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Tibialis, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Tibialis Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Tibialis SRS2528188 SAMN07675868 GSM2788699 Het(Q175)_Cortex_Male_CHDI-00390576_100mg/kg_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Cortex, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Cortex Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Cortex SRS2528237 SAMN07675781 GSM2788749 Het(Q175)_Tibialis_Female_CHDI-00390576_30mg/kg_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Tibialis, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Tibialis Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Tibialis SRS2528190 SAMN07675865 GSM2788702 Het(Q175)_Cortex_Male_CHDI-00390576_30mg/kg_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Cortex, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Cortex Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Cortex SRS2528239 SAMN07675787 GSM2788751 Het(Q175)_Tibialis_Male_CHDI-00390576_30mg/kg_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Tibialis, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Tibialis Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Tibialis SRS2528192 SAMN07675863 GSM2788704 Het(Q175)_Cortex_Female_CHDI-00390576_30mg/kg_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Cortex, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Cortex Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Cortex SRS2528241 SAMN07675785 GSM2788753 Het(Q175)_Tibialis_Female_Vehicle_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Tibialis, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Tibialis Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Tibialis SRS2528194 SAMN07675861 GSM2788706 Het(Q175)_Cortex_Male_CHDI-00390576_30mg/kg_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Cortex, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Cortex Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Cortex SRS2528243 SAMN07675783 GSM2788755 WT_Tibialis_Female_Vehicle_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Tibialis, Vehicle background strain C57BL/6J genotype Wild Type tissue Tibialis Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Tibialis SRS2528196 SAMN07675859 GSM2788708 Het(Q175)_Cortex_Female_Vehicle_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Cortex, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Cortex Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Cortex SRS2528245 SAMN07675777 GSM2788758 Het(Q175)_Heart_Male_Vehicle_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Heart, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Heart Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Heart SRS2528198 SAMN07675857 GSM2788710 Het(Q175)_Cortex_Male_CHDI-00390576_30mg/kg_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Cortex, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Cortex Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Cortex SRS2528247 SAMN07675776 GSM2788759 WT_Heart_Female_Vehicle_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Heart, Vehicle background strain C57BL/6J genotype Wild Type tissue Heart Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Heart SRS2528202 SAMN07675925 GSM2788714 WT_Cortex_Female_Vehicle_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Cortex, Vehicle background strain C57BL/6J genotype Wild Type tissue Cortex Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Cortex SRS2528249 SAMN07675774 GSM2788761 Het(Q175)_Heart_Male_Vehicle_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Heart, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Heart Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Heart SRS2528204 SAMN07675923 GSM2788716 Het(Q175)_Cortex_Female_Vehicle_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Cortex, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Cortex Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Cortex SRS2528251 SAMN07675772 GSM2788763 Het(Q175)_Heart_Female_Vehicle_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Heart, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Heart Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Heart SRS2528252 SAMN07675769 GSM2788766 WT_Heart_Male_Vehicle_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Heart, Vehicle background strain C57BL/6J genotype Wild Type tissue Heart Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Heart SRS2528206 SAMN07675922 GSM2788717 Het(Q175)_Cortex_Male_Vehicle_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Cortex, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Cortex Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Cortex SRS2528254 SAMN07675770 GSM2788765 WT_Heart_Female_Vehicle_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Heart, Vehicle background strain C57BL/6J genotype Wild Type tissue Heart Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Heart SRS2528255 SAMN07675768 GSM2788767 WT_Heart_Male_Vehicle_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Heart, Vehicle background strain C57BL/6J genotype Wild Type tissue Heart Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Heart SRS2528208 SAMN07675815 GSM2788720 WT_Cortex_Male_Vehicle_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Cortex, Vehicle background strain C57BL/6J genotype Wild Type tissue Cortex Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Cortex SRS2528257 SAMN07675919 GSM2788768 Het(Q175)_Heart_Male_CHDI-00390576_30mg/kg_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Heart, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Heart Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Heart SRS2528210 SAMN07675813 GSM2788722 Het(Q175)_Cortex_Male_Vehicle_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Cortex, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Cortex Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Cortex SRS2528259 SAMN07675917 GSM2788770 Het(Q175)_Heart_Female_CHDI-00390576_100mg/kg_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Heart, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Heart Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Heart SRS2528212 SAMN07675811 GSM2788724 Het(Q175)_Tibialis_Male_CHDI-00390576_30mg/kg_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Tibialis, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Tibialis Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Tibialis SRS2528261 SAMN07675914 GSM2788773 Het(Q175)_Heart_Male_Vehicle_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Heart, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Heart Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Heart SRS2528214 SAMN07675809 GSM2788726 Het(Q175)_Tibialis_Female_CHDI-00390576_30mg/kg_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Tibialis, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Tibialis Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Tibialis SRS2528263 SAMN07675911 GSM2788776 Het(Q175)_Heart_Female_CHDI-00390576_100mg/kg_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Heart, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Heart Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Heart SRS2528216 SAMN07675807 GSM2788728 WT_Tibialis_Female_Vehicle_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Tibialis, Vehicle background strain C57BL/6J genotype Wild Type tissue Tibialis Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Tibialis SRS2528265 SAMN07675910 GSM2788777 Het(Q175)_Heart_Female_CHDI-00390576_30mg/kg_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Heart, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Heart Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Heart SRS2528218 SAMN07675805 GSM2788730 Het(Q175)_Tibialis_Male_CHDI-00390576_100mg/kg_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Tibialis, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Tibialis Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Tibialis SRS2528267 SAMN07675908 GSM2788779 Het(Q175)_Heart_Male_CHDI-00390576_100mg/kg_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Heart, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Heart Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Heart SRS2528220 SAMN07675803 GSM2788732 Het(Q175)_Tibialis_Male_Vehicle_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Tibialis, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Tibialis Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Tibialis SRS2528269 SAMN07675906 GSM2788781 Het(Q175)_Heart_Female_Vehicle_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Heart, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Heart Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Heart SRS2528222 SAMN07675801 GSM2788734 Het(Q175)_Tibialis_Male_CHDI-00390576_100mg/kg_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Tibialis, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Tibialis Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Tibialis SRS2528271 SAMN07675904 GSM2788783 Het(Q175)_Heart_Female_CHDI-00390576_100mg/kg_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Heart, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Heart Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Heart SRS2528224 SAMN07675799 GSM2788736 Het(Q175)_Tibialis_Female_CHDI-00390576_100mg/kg_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Tibialis, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Tibialis Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Tibialis SRS2528273 SAMN07675902 GSM2788785 Het(Q175)_Heart_Female_CHDI-00390576_30mg/kg_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Heart, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Heart Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Heart SRS2528226 SAMN07675797 GSM2788738 WT_Tibialis_Female_Vehicle_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Tibialis, Vehicle background strain C57BL/6J genotype Wild Type tissue Tibialis Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Tibialis SRS2528275 SAMN07675900 GSM2788787 Het(Q175)_Heart_Male_CHDI-00390576_100mg/kg_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Heart, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Heart Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Heart SRS2528200 SAMN07675855 GSM2788712 WT_Cortex_Male_Vehicle_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Cortex, Vehicle background strain C57BL/6J genotype Wild Type tissue Cortex Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Cortex SRS2528228 SAMN07675795 GSM2788740 Het(Q175)_Tibialis_Female_CHDI-00390576_100mg/kg_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Tibialis, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Tibialis Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Tibialis SRS2528230 SAMN07675793 GSM2788742 WT_Tibialis_Female_Vehicle_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Tibialis, Vehicle background strain C57BL/6J genotype Wild Type tissue Tibialis Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Tibialis SRS2528232 SAMN07675791 GSM2788744 WT_Tibialis_Male_Vehicle_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Tibialis, Vehicle background strain C57BL/6J genotype Wild Type tissue Tibialis Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Tibialis SRS2528234 SAMN07675789 GSM2788746 Het(Q175)_Tibialis_Female_Vehicle_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Tibialis, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Tibialis Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Tibialis SRS2528236 SAMN07675782 GSM2788748 Het(Q175)_Tibialis_Male_CHDI-00390576_100mg/kg_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Tibialis, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Tibialis Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Tibialis SRS2528238 SAMN07675780 GSM2788750 Het(Q175)_Tibialis_Female_Vehicle_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Tibialis, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Tibialis Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Tibialis SRS2528240 SAMN07675786 GSM2788752 Het(Q175)_Tibialis_Male_Vehicle_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Tibialis, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Tibialis Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Tibialis SRS2528242 SAMN07675784 GSM2788754 WT_Tibialis_Male_Vehicle_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Tibialis, Vehicle background strain C57BL/6J genotype Wild Type tissue Tibialis Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Tibialis SRS2528244 SAMN07675779 GSM2788756 Het(Q175)_Heart_Male_CHDI-00390576_100mg/kg_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Heart, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Heart Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Heart SRS2528246 SAMN07675778 GSM2788757 WT_Heart_Female_Vehicle_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Heart, Vehicle background strain C57BL/6J genotype Wild Type tissue Heart Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Heart SRS2528248 SAMN07675775 GSM2788760 Het(Q175)_Heart_Male_CHDI-00390576_30mg/kg_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Heart, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Heart Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Heart SRS2528250 SAMN07675773 GSM2788762 WT_Heart_Male_Vehicle_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Heart, Vehicle background strain C57BL/6J genotype Wild Type tissue Heart Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Heart SRS2528253 SAMN07675771 GSM2788764 Het(Q175)_Heart_Female_Vehicle_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Heart, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Heart Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Heart SRS2528256 SAMN07675918 GSM2788769 Het(Q175)_Heart_Female_CHDI-00390576_30mg/kg_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Heart, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Heart Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Heart SRS2528258 SAMN07675916 GSM2788771 Het(Q175)_Heart_Female_CHDI-00390576_30mg/kg_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Heart, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Heart Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Heart SRS2528260 SAMN07675915 GSM2788772 Het(Q175)_Heart_Male_CHDI-00390576_30mg/kg_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Heart, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Heart Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Heart SRS2528262 SAMN07675913 GSM2788774 Het(Q175)_Heart_Male_Vehicle_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Heart, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Heart Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Heart SRS2528264 SAMN07675912 GSM2788775 WT_Heart_Female_Vehicle_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Heart, Vehicle background strain C57BL/6J genotype Wild Type tissue Heart Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Heart SRS2528266 SAMN07675909 GSM2788778 Het(Q175)_Heart_Male_CHDI-00390576_100mg/kg_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Heart, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Heart Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Heart SRS2528268 SAMN07675907 GSM2788780 WT_Heart_Male_Vehicle_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Heart, Vehicle background strain C57BL/6J genotype Wild Type tissue Heart Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Heart SRS2528270 SAMN07675905 GSM2788782 Het(Q175)_Heart_Female_CHDI-00390576_100mg/kg_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Heart, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Heart Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Heart SRS2528272 SAMN07675903 GSM2788784 Het(Q175)_Heart_Male_CHDI-00390576_30mg/kg_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Heart, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Heart Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Heart SRS2528274 SAMN07675901 GSM2788786 Het(Q175)_Heart_Female_Vehicle_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Heart, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Heart Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Heart SRS2528276 SAMN07675899 GSM2788788 Het(Q175)_Liver_Female_CHDI-00390576_30mg/kg_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Liver, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Liver Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Liver SRS2528277 SAMN07675897 GSM2788790 Het(Q175)_Liver_Female_CHDI-00390576_100mg/kg_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Liver, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Liver Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Liver SRS2528278 SAMN07675898 GSM2788789 Het(Q175)_Liver_Male_Vehicle_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Liver, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Liver Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Liver SRS2528279 SAMN07675895 GSM2788792 Het(Q175)_Liver_Male_Vehicle_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Liver, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Liver Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Liver SRS2528280 SAMN07675896 GSM2788791 WT_Liver_Male_Vehicle_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Liver, Vehicle background strain C57BL/6J genotype Wild Type tissue Liver Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Liver SRS2528281 SAMN07675894 GSM2788793 WT_Liver_Male_Vehicle_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Liver, Vehicle background strain C57BL/6J genotype Wild Type tissue Liver Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Liver SRS2528282 SAMN07675893 GSM2788794 WT_Liver_Female_Vehicle_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Liver, Vehicle background strain C57BL/6J genotype Wild Type tissue Liver Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Liver SRS2528283 SAMN07675892 GSM2788795 Het(Q175)_Liver_Female_CHDI-00390576_30mg/kg_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Liver, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Liver Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Liver SRS2528284 SAMN07675891 GSM2788796 WT_Liver_Female_Vehicle_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Liver, Vehicle background strain C57BL/6J genotype Wild Type tissue Liver Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Liver SRS2528285 SAMN07675890 GSM2788797 Het(Q175)_Liver_Female_Vehicle_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Liver, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Liver Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Liver SRS2528286 SAMN07675889 GSM2788798 WT_Liver_Male_Vehicle_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Liver, Vehicle background strain C57BL/6J genotype Wild Type tissue Liver Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Liver SRS2528287 SAMN07675888 GSM2788799 WT_Liver_Female_Vehicle_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Liver, Vehicle background strain C57BL/6J genotype Wild Type tissue Liver Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Liver SRS2528288 SAMN07675887 GSM2788800 Het(Q175)_Liver_Male_Vehicle_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Liver, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Liver Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Liver SRS2528289 SAMN07675886 GSM2788801 WT_Liver_Female_Vehicle_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Liver, Vehicle background strain C57BL/6J genotype Wild Type tissue Liver Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Liver SRS2528290 SAMN07675885 GSM2788802 Het(Q175)_Liver_Female_CHDI-00390576_30mg/kg_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Liver, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Liver Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Liver SRS2528291 SAMN07675884 GSM2788803 Het(Q175)_Liver_Female_Vehicle_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Liver, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Liver Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Liver SRS2528292 SAMN07675883 GSM2788804 Het(Q175)_Liver_Male_CHDI-00390576_100mg/kg_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Liver, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Liver Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Liver SRS2528293 SAMN07675882 GSM2788805 Het(Q175)_Liver_Male_CHDI-00390576_30mg/kg_rep1 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Liver, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Liver Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Liver SRS2528294 SAMN07675880 GSM2788807 Het(Q175)_Liver_Female_CHDI-00390576_30mg/kg_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Liver, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Liver Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Liver SRS2528295 SAMN07675881 GSM2788806 WT_Liver_Male_Vehicle_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Liver, Vehicle background strain C57BL/6J genotype Wild Type tissue Liver Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Liver SRS2528296 SAMN07675878 GSM2788809 Het(Q175)_Liver_Male_CHDI-00390576_30mg/kg_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Liver, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Liver Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Liver SRS2528297 SAMN07675767 GSM2788810 Het(Q175)_Liver_Male_CHDI-00390576_30mg/kg_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Liver, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Liver Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Liver SRS2528298 SAMN07675879 GSM2788808 Het(Q175)_Liver_Female_CHDI-00390576_100mg/kg_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Liver, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Liver Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Liver SRS2528299 SAMN07675766 GSM2788811 Het(Q175)_Liver_Male_CHDI-00390576_100mg/kg_rep2 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Liver, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Liver Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Liver SRS2528300 SAMN07675853 GSM2788812 Het(Q175)_Liver_Female_CHDI-00390576_100mg/kg_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Liver, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Liver Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Liver SRS2528301 SAMN07675851 GSM2788814 Het(Q175)_Liver_Male_CHDI-00390576_100mg/kg_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Liver, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Liver Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Liver SRS2528302 SAMN07675852 GSM2788813 Het(Q175)_Liver_Male_Vehicle_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Liver, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Liver Sex male age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Liver SRS2528303 SAMN07675850 GSM2788815 Het(Q175)_Liver_Female_Vehicle_rep3 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Liver, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Liver Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Liver SRS2528304 SAMN07675849 GSM2788816 Het(Q175)_Liver_Female_Vehicle_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Liver, Vehicle background strain C57BL/6J genotype Het(Q175) knock-in tissue Liver Sex female age 6 months treatment duration from 4 weeks to 6 months treatment Vehicle treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Liver SRS2528305 SAMN07675848 GSM2788817 Het(Q175)_Liver_Male_CHDI-00390576_30mg/kg_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Liver, CHDI-00390576, 30 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Liver Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 30 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Liver SRS2528306 SAMN07675847 GSM2788818 Het(Q175)_Liver_Female_CHDI-00390576_100mg/kg_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Liver, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Liver Sex female age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Liver SRS2528307 SAMN07675846 GSM2788819 Het(Q175)_Liver_Male_CHDI-00390576_100mg/kg_rep4 10090 Mus musculus bioproject 408141 PRJNA408141 source_name Liver, CHDI-00390576, 100 mg/kg background strain C57BL/6J genotype Het(Q175) knock-in tissue Liver Sex male age 6 months treatment duration from 4 weeks to 6 months treatment CHDI-00390576 treatment dose 100 mg/kg treatment administration route Oral treatment frequency Twice-Daily (b.i.d) tissue Liver