<?xml version="1.0" encoding="UTF-8"?>
<STUDY_SET xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <STUDY center_name="BioProject" alias="PRJNA417493" accession="SRP125265">
    <IDENTIFIERS>
      <PRIMARY_ID>SRP125265</PRIMARY_ID>
      <EXTERNAL_ID namespace="BioProject" label="primary">PRJNA417493</EXTERNAL_ID>
    </IDENTIFIERS>
    <DESCRIPTOR>
      <STUDY_TITLE>Synthetic nucleocapsid strain:I53-50 Raw sequence reads</STUDY_TITLE>
      <STUDY_TYPE existing_study_type="Other"/>
      <STUDY_ABSTRACT>Raw sequencing reads from Butterfield and Lajoie, et al. Nature (2017) Evolution of a Designed Protein Assembly Encapsulating its Own RNA Genome.Sequencing was used to evaluate variants exhibiting improved fitness for in vitro (nuclease resistance, blood resistance) or in vivo (circulation time in living mice) selections. Additionally, sequencing was used to evaluate the RNAs encapsulated by synthetic nucleocapsids.</STUDY_ABSTRACT>
      <CENTER_PROJECT_NAME>Synthetic nucleocapsid strain:I53-50</CENTER_PROJECT_NAME>
    </DESCRIPTOR>
    <STUDY_LINKS>
      <STUDY_LINK>
        <XREF_LINK>
          <DB>pubmed</DB>
          <ID>29236688</ID>
        </XREF_LINK>
      </STUDY_LINK>
    </STUDY_LINKS>
  </STUDY>
</STUDY_SET>
