<?xml version="1.0" encoding="UTF-8"?>
<STUDY_SET xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <STUDY center_name="BioProject" alias="PRJNA419915" accession="SRP125688">
    <IDENTIFIERS>
      <PRIMARY_ID>SRP125688</PRIMARY_ID>
      <EXTERNAL_ID namespace="BioProject" label="primary">PRJNA419915</EXTERNAL_ID>
    </IDENTIFIERS>
    <DESCRIPTOR>
      <STUDY_TITLE>Human immunodeficiency virus 1 near full length genome sequencing by NGS</STUDY_TITLE>
      <STUDY_TYPE existing_study_type="Other"/>
      <STUDY_ABSTRACT>In the context of a remarkable HIV-1 genetic variability, quasispecies generated during infection can influence virus persistence and pathogenicity, representing a challenge to treatment. However, the clinical relevance of minority quasispecies is still uncertain. For this study, we have determined the archived proviral sequences, viral subtype and drug resistance mutations from a cohort of HIV+ patients with undetectable viral load undergoing HAART as first-line therapy using next-generation sequencing for near full-length virus genome (NFLG) assembly.</STUDY_ABSTRACT>
      <CENTER_PROJECT_NAME>Human immunodeficiency virus 1</CENTER_PROJECT_NAME>
    </DESCRIPTOR>
  </STUDY>
</STUDY_SET>
