<?xml version="1.0" encoding="UTF-8"?>
<STUDY_SET xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <STUDY center_name="GEO" alias="GSE107724" accession="SRP126186">
    <IDENTIFIERS>
      <PRIMARY_ID>SRP126186</PRIMARY_ID>
      <EXTERNAL_ID namespace="BioProject" label="primary">PRJNA421194</EXTERNAL_ID>
      <EXTERNAL_ID namespace="GEO">GSE107724</EXTERNAL_ID>
    </IDENTIFIERS>
    <DESCRIPTOR>
      <STUDY_TITLE>DNA accessibility in CD8+  tumour-infiltrating T cells treated with Phenelzine.</STUDY_TITLE>
      <STUDY_TYPE existing_study_type="Other"/>
      <STUDY_ABSTRACT>Phenelzine treatments were conducted in tumour-bearing Balb/c mice and then 4T1 tumours were acquired. CD8+ tumour-infiltrating T cells were positively selected by using mouse CD8a (Ly-2) microbeads and isolated by autoMACS Separator with recommended programs. Then isolated CD8 T cells were stimulated by PMA and Ionomycin. Global ATAC-seq analysis was performed to identify the dynamic changes in chromatin accessibility of tumour-filtrating CD8 T cells after phenelzine treatment. Overall design: 4 individual samples, no replicates.</STUDY_ABSTRACT>
      <CENTER_PROJECT_NAME>GSE107724</CENTER_PROJECT_NAME>
    </DESCRIPTOR>
  </STUDY>
</STUDY_SET>
