<?xml version="1.0" encoding="UTF-8"?>
<STUDY_SET xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <STUDY center_name="GEO" alias="GSE107762" accession="SRP126247">
    <IDENTIFIERS>
      <PRIMARY_ID>SRP126247</PRIMARY_ID>
      <EXTERNAL_ID namespace="BioProject" label="primary">PRJNA421322</EXTERNAL_ID>
      <EXTERNAL_ID namespace="GEO">GSE107762</EXTERNAL_ID>
    </IDENTIFIERS>
    <DESCRIPTOR>
      <STUDY_TITLE>Identification of PRMT5-dependent genes in ESA+CD24lowCD44+ MCF7 cells</STUDY_TITLE>
      <STUDY_TYPE existing_study_type="Transcriptome Analysis"/>
      <STUDY_ABSTRACT>PRMT5 has been associated with poor prognosis in breast cancer. Here, we identify genes which are dependent on PRMT5 expression in MCF7 ESA+CD24lowCD44+ breast cancer stem cells by RNA-seq Overall design: RNA-seq profiling of ESA+CD24lowCD44+ cells from MCF7 shCTRL or shPRMT5 cell lines. Three independent ESA+CD24lowCD44+ cell populations from MCF7 shCTRL or shPRMT5 cells were isolated by flow cytometry.</STUDY_ABSTRACT>
      <CENTER_PROJECT_NAME>GSE107762</CENTER_PROJECT_NAME>
    </DESCRIPTOR>
    <STUDY_LINKS>
      <STUDY_LINK>
        <XREF_LINK>
          <DB>pubmed</DB>
          <ID>29262329</ID>
        </XREF_LINK>
      </STUDY_LINK>
    </STUDY_LINKS>
  </STUDY>
</STUDY_SET>
