SRX3798597 GSM3044547 SRP135793 SRS3050676 GSM3044547 OTHER TRANSCRIPTOMIC other HITS-CLIP: cells were UV-crosslinked (400mJ, Stratalinker 2400, Stratagene). RNA–protein complexes were immunoprecipitated with anti-Flag M2 Agarose beads (Sigma). RNA was partially digested with RNase A (Affymetrix) and P32-labeled (Perkin Elmer). SRSF2-RNA complexes were isolated by SDS-PAGE, treated with proteinase K, followed by RNA linker ligation. RNA_seq: QIAGEN RNeasy minikit protocol HITS-CLIP: Ilumina small RNA library protocol for linker ligation. RNA-seq: rRNA depletion Illumina Genome Analyzer IIx gds 303044547 GSM3044547 GEO Accession GSM3044547 SRX3798598 GSM3044548 SRP135793 SRS3050677 GSM3044548 OTHER TRANSCRIPTOMIC other HITS-CLIP: cells were UV-crosslinked (400mJ, Stratalinker 2400, Stratagene). RNA–protein complexes were immunoprecipitated with anti-Flag M2 Agarose beads (Sigma). RNA was partially digested with RNase A (Affymetrix) and P32-labeled (Perkin Elmer). SRSF2-RNA complexes were isolated by SDS-PAGE, treated with proteinase K, followed by RNA linker ligation. RNA_seq: QIAGEN RNeasy minikit protocol HITS-CLIP: Ilumina small RNA library protocol for linker ligation. RNA-seq: rRNA depletion Illumina Genome Analyzer IIx gds 303044548 GSM3044548 GEO Accession GSM3044548 SRX3798599 GSM3044549 SRP135793 SRS3050678 GSM3044549 OTHER TRANSCRIPTOMIC other HITS-CLIP: cells were UV-crosslinked (400mJ, Stratalinker 2400, Stratagene). RNA–protein complexes were immunoprecipitated with anti-Flag M2 Agarose beads (Sigma). RNA was partially digested with RNase A (Affymetrix) and P32-labeled (Perkin Elmer). SRSF2-RNA complexes were isolated by SDS-PAGE, treated with proteinase K, followed by RNA linker ligation. RNA_seq: QIAGEN RNeasy minikit protocol HITS-CLIP: Ilumina small RNA library protocol for linker ligation. RNA-seq: rRNA depletion Illumina Genome Analyzer IIx gds 303044549 GSM3044549 GEO Accession GSM3044549 SRX3798600 GSM3044550 SRP135793 SRS3050679 GSM3044550 OTHER TRANSCRIPTOMIC other HITS-CLIP: cells were UV-crosslinked (400mJ, Stratalinker 2400, Stratagene). RNA–protein complexes were immunoprecipitated with anti-Flag M2 Agarose beads (Sigma). RNA was partially digested with RNase A (Affymetrix) and P32-labeled (Perkin Elmer). SRSF2-RNA complexes were isolated by SDS-PAGE, treated with proteinase K, followed by RNA linker ligation. RNA_seq: QIAGEN RNeasy minikit protocol HITS-CLIP: Ilumina small RNA library protocol for linker ligation. RNA-seq: rRNA depletion Illumina Genome Analyzer IIx gds 303044550 GSM3044550 GEO Accession GSM3044550 SRX3798601 GSM3044551 SRP135793 SRS3050680 GSM3044551 OTHER TRANSCRIPTOMIC other HITS-CLIP: cells were UV-crosslinked (400mJ, Stratalinker 2400, Stratagene). RNA–protein complexes were immunoprecipitated with anti-Flag M2 Agarose beads (Sigma). RNA was partially digested with RNase A (Affymetrix) and P32-labeled (Perkin Elmer). SRSF2-RNA complexes were isolated by SDS-PAGE, treated with proteinase K, followed by RNA linker ligation. RNA_seq: QIAGEN RNeasy minikit protocol HITS-CLIP: Ilumina small RNA library protocol for linker ligation. RNA-seq: rRNA depletion Illumina Genome Analyzer IIx gds 303044551 GSM3044551 GEO Accession GSM3044551 SRX3798602 GSM3044552 SRP135793 SRS3050681 GSM3044552 OTHER TRANSCRIPTOMIC other HITS-CLIP: cells were UV-crosslinked (400mJ, Stratalinker 2400, Stratagene). RNA–protein complexes were immunoprecipitated with anti-Flag M2 Agarose beads (Sigma). RNA was partially digested with RNase A (Affymetrix) and P32-labeled (Perkin Elmer). SRSF2-RNA complexes were isolated by SDS-PAGE, treated with proteinase K, followed by RNA linker ligation. RNA_seq: QIAGEN RNeasy minikit protocol HITS-CLIP: Ilumina small RNA library protocol for linker ligation. RNA-seq: rRNA depletion Illumina Genome Analyzer IIx gds 303044552 GSM3044552 GEO Accession GSM3044552 SRX3798603 GSM3044553 SRP135793 SRS3050682 GSM3044553 OTHER TRANSCRIPTOMIC other HITS-CLIP: cells were UV-crosslinked (400mJ, Stratalinker 2400, Stratagene). RNA–protein complexes were immunoprecipitated with anti-Flag M2 Agarose beads (Sigma). RNA was partially digested with RNase A (Affymetrix) and P32-labeled (Perkin Elmer). SRSF2-RNA complexes were isolated by SDS-PAGE, treated with proteinase K, followed by RNA linker ligation. RNA_seq: QIAGEN RNeasy minikit protocol HITS-CLIP: Ilumina small RNA library protocol for linker ligation. RNA-seq: rRNA depletion Illumina Genome Analyzer IIx gds 303044553 GSM3044553 GEO Accession GSM3044553 SRX3798604 GSM3044554 SRP135793 SRS3050685 GSM3044554 OTHER TRANSCRIPTOMIC other HITS-CLIP: cells were UV-crosslinked (400mJ, Stratalinker 2400, Stratagene). RNA–protein complexes were immunoprecipitated with anti-Flag M2 Agarose beads (Sigma). RNA was partially digested with RNase A (Affymetrix) and P32-labeled (Perkin Elmer). SRSF2-RNA complexes were isolated by SDS-PAGE, treated with proteinase K, followed by RNA linker ligation. RNA_seq: QIAGEN RNeasy minikit protocol HITS-CLIP: Ilumina small RNA library protocol for linker ligation. RNA-seq: rRNA depletion Illumina Genome Analyzer IIx gds 303044554 GSM3044554 GEO Accession GSM3044554 SRX3798605 GSM3044555 SRP135793 SRS3050684 GSM3044555 RNA-Seq TRANSCRIPTOMIC cDNA HITS-CLIP: cells were UV-crosslinked (400mJ, Stratalinker 2400, Stratagene). RNA–protein complexes were immunoprecipitated with anti-Flag M2 Agarose beads (Sigma). RNA was partially digested with RNase A (Affymetrix) and P32-labeled (Perkin Elmer). SRSF2-RNA complexes were isolated by SDS-PAGE, treated with proteinase K, followed by RNA linker ligation. RNA_seq: QIAGEN RNeasy minikit protocol HITS-CLIP: Ilumina small RNA library protocol for linker ligation. RNA-seq: rRNA depletion Illumina HiSeq 4000 gds 303044555 GSM3044555 GEO Accession GSM3044555 SRX3798606 GSM3044556 SRP135793 SRS3050683 GSM3044556 RNA-Seq TRANSCRIPTOMIC cDNA HITS-CLIP: cells were UV-crosslinked (400mJ, Stratalinker 2400, Stratagene). RNA–protein complexes were immunoprecipitated with anti-Flag M2 Agarose beads (Sigma). RNA was partially digested with RNase A (Affymetrix) and P32-labeled (Perkin Elmer). SRSF2-RNA complexes were isolated by SDS-PAGE, treated with proteinase K, followed by RNA linker ligation. RNA_seq: QIAGEN RNeasy minikit protocol HITS-CLIP: Ilumina small RNA library protocol for linker ligation. RNA-seq: rRNA depletion Illumina HiSeq 4000 gds 303044556 GSM3044556 GEO Accession GSM3044556 SRX3798607 GSM3044557 SRP135793 SRS3050687 GSM3044557 RNA-Seq TRANSCRIPTOMIC cDNA HITS-CLIP: cells were UV-crosslinked (400mJ, Stratalinker 2400, Stratagene). RNA–protein complexes were immunoprecipitated with anti-Flag M2 Agarose beads (Sigma). RNA was partially digested with RNase A (Affymetrix) and P32-labeled (Perkin Elmer). SRSF2-RNA complexes were isolated by SDS-PAGE, treated with proteinase K, followed by RNA linker ligation. RNA_seq: QIAGEN RNeasy minikit protocol HITS-CLIP: Ilumina small RNA library protocol for linker ligation. RNA-seq: rRNA depletion Illumina HiSeq 4000 gds 303044557 GSM3044557 GEO Accession GSM3044557 SRX3798608 GSM3044558 SRP135793 SRS3050686 GSM3044558 RNA-Seq TRANSCRIPTOMIC cDNA HITS-CLIP: cells were UV-crosslinked (400mJ, Stratalinker 2400, Stratagene). RNA–protein complexes were immunoprecipitated with anti-Flag M2 Agarose beads (Sigma). RNA was partially digested with RNase A (Affymetrix) and P32-labeled (Perkin Elmer). SRSF2-RNA complexes were isolated by SDS-PAGE, treated with proteinase K, followed by RNA linker ligation. RNA_seq: QIAGEN RNeasy minikit protocol HITS-CLIP: Ilumina small RNA library protocol for linker ligation. RNA-seq: rRNA depletion Illumina HiSeq 4000 gds 303044558 GSM3044558 GEO Accession GSM3044558 SRX3798609 GSM3044559 SRP135793 SRS3050688 GSM3044559 RNA-Seq TRANSCRIPTOMIC cDNA HITS-CLIP: cells were UV-crosslinked (400mJ, Stratalinker 2400, Stratagene). RNA–protein complexes were immunoprecipitated with anti-Flag M2 Agarose beads (Sigma). RNA was partially digested with RNase A (Affymetrix) and P32-labeled (Perkin Elmer). SRSF2-RNA complexes were isolated by SDS-PAGE, treated with proteinase K, followed by RNA linker ligation. RNA_seq: QIAGEN RNeasy minikit protocol HITS-CLIP: Ilumina small RNA library protocol for linker ligation. RNA-seq: rRNA depletion Illumina HiSeq 4000 gds 303044559 GSM3044559 GEO Accession GSM3044559