<?xml version="1.0" encoding="UTF-8"?>
<STUDY_SET xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <STUDY center_name="GEO" alias="GSE116327" accession="SRP151434">
    <IDENTIFIERS>
      <PRIMARY_ID>SRP151434</PRIMARY_ID>
      <EXTERNAL_ID namespace="BioProject" label="primary">PRJNA478185</EXTERNAL_ID>
      <EXTERNAL_ID namespace="GEO">GSE116327</EXTERNAL_ID>
    </IDENTIFIERS>
    <DESCRIPTOR>
      <STUDY_TITLE>Gene expression changes associated with Alexander disease (AxD)</STUDY_TITLE>
      <STUDY_TYPE existing_study_type="Transcriptome Analysis"/>
      <STUDY_ABSTRACT>We use human induced pluripotent stem cell (hiPSC)-derived astrocytes and post-mortem human brain tissues to study gene expression changes associated with AxD Overall design: To compare gene expression profiles in healthy control and AxD patient iPSC-derived astrocytes and post-mortem brain tissues</STUDY_ABSTRACT>
      <CENTER_PROJECT_NAME>GSE116327</CENTER_PROJECT_NAME>
    </DESCRIPTOR>
  </STUDY>
</STUDY_SET>
