SRX4394654 GSM3272800 SRP153922 PRJNA481340 SRS3549905 SAMN09665797 ncRNA-Seq TRANSCRIPTOMIC size fractionation Total RNA was used directly for library preparation. Total RNA was extracted using a miRNAeasy mini kit (Qiagen) following manufacturer's instructions. RNA was treated with Turbo DNA-free kit (Thermo Fisher) to remove residual DNA. Libraries were prepared using the CleanTag small RNA library prep kit according to manufacturer's instructions, using total RNA from adult worms (30 ng), and sucrose-gradient purified EVs (equivalent 1E10 EVs measured by Nanosight, Malvern). For all samples, 1:12 dilutions of both adapters were used with 18 amplification cycles (TriLink BioTechnologies). Fragments between 140-170bp were size selected and sequenced on an Illumina HiSeq high output v4 50bp SE in Edinburgh Genomics. Illumina HiSeq 2500 gds 303272800 GSM3272800 GEO Accession GSM3272800 SRX4394655 GSM3272801 SRP153922 PRJNA481340 SRS3549906 SAMN09665793 ncRNA-Seq TRANSCRIPTOMIC size fractionation Total RNA was used directly for library preparation. Total RNA was extracted using a miRNAeasy mini kit (Qiagen) following manufacturer's instructions. RNA was treated with Turbo DNA-free kit (Thermo Fisher) to remove residual DNA. Libraries were prepared using the CleanTag small RNA library prep kit according to manufacturer's instructions, using total RNA from adult worms (30 ng), and sucrose-gradient purified EVs (equivalent 1E10 EVs measured by Nanosight, Malvern). For all samples, 1:12 dilutions of both adapters were used with 18 amplification cycles (TriLink BioTechnologies). Fragments between 140-170bp were size selected and sequenced on an Illumina HiSeq high output v4 50bp SE in Edinburgh Genomics. Illumina HiSeq 2500 gds 303272801 GSM3272801 GEO Accession GSM3272801 SRX4394656 GSM3272802 SRP153922 PRJNA481340 SRS3549907 SAMN09665792 ncRNA-Seq TRANSCRIPTOMIC size fractionation Total RNA was used directly for library preparation. Total RNA was extracted using a miRNAeasy mini kit (Qiagen) following manufacturer's instructions. RNA was treated with Turbo DNA-free kit (Thermo Fisher) to remove residual DNA. Libraries were prepared using the CleanTag small RNA library prep kit according to manufacturer's instructions, using total RNA from adult worms (30 ng), and sucrose-gradient purified EVs (equivalent 1E10 EVs measured by Nanosight, Malvern). For all samples, 1:12 dilutions of both adapters were used with 18 amplification cycles (TriLink BioTechnologies). Fragments between 140-170bp were size selected and sequenced on an Illumina HiSeq high output v4 50bp SE in Edinburgh Genomics. Illumina HiSeq 2500 gds 303272802 GSM3272802 GEO Accession GSM3272802 SRX4394657 GSM3272803 SRP153922 PRJNA481340 SRS3549908 SAMN09665791 ncRNA-Seq TRANSCRIPTOMIC size fractionation Total RNA was treated with RNA 5' Polyphosphatase (Epicenter) following manufacturer's instructions, before library preparation. Total RNA was extracted using a miRNAeasy mini kit (Qiagen) following manufacturer's instructions. RNA was treated with Turbo DNA-free kit (Thermo Fisher) to remove residual DNA. Libraries were prepared using the CleanTag small RNA library prep kit according to manufacturer's instructions, using total RNA from adult worms (30 ng), and sucrose-gradient purified EVs (equivalent 1E10 EVs measured by Nanosight, Malvern). For all samples, 1:12 dilutions of both adapters were used with 18 amplification cycles (TriLink BioTechnologies). Fragments between 140-170bp were size selected and sequenced on an Illumina HiSeq high output v4 50bp SE in Edinburgh Genomics. Illumina HiSeq 2500 gds 303272803 GSM3272803 GEO Accession GSM3272803 SRX4394658 GSM3272804 SRP153922 PRJNA481340 SRS3549909 SAMN09665789 ncRNA-Seq TRANSCRIPTOMIC size fractionation Total RNA was treated with RNA 5' Polyphosphatase (Epicenter) following manufacturer's instructions, before library preparation. Total RNA was extracted using a miRNAeasy mini kit (Qiagen) following manufacturer's instructions. RNA was treated with Turbo DNA-free kit (Thermo Fisher) to remove residual DNA. Libraries were prepared using the CleanTag small RNA library prep kit according to manufacturer's instructions, using total RNA from adult worms (30 ng), and sucrose-gradient purified EVs (equivalent 1E10 EVs measured by Nanosight, Malvern). For all samples, 1:12 dilutions of both adapters were used with 18 amplification cycles (TriLink BioTechnologies). Fragments between 140-170bp were size selected and sequenced on an Illumina HiSeq high output v4 50bp SE in Edinburgh Genomics. Illumina HiSeq 2500 gds 303272804 GSM3272804 GEO Accession GSM3272804 SRX4394659 GSM3272805 SRP153922 PRJNA481340 SRS3549910 SAMN09665786 ncRNA-Seq TRANSCRIPTOMIC size fractionation Total RNA was treated with RNA 5' Polyphosphatase (Epicenter) following manufacturer's instructions, before library preparation. Total RNA was extracted using a miRNAeasy mini kit (Qiagen) following manufacturer's instructions. RNA was treated with Turbo DNA-free kit (Thermo Fisher) to remove residual DNA. Libraries were prepared using the CleanTag small RNA library prep kit according to manufacturer's instructions, using total RNA from adult worms (30 ng), and sucrose-gradient purified EVs (equivalent 1E10 EVs measured by Nanosight, Malvern). For all samples, 1:12 dilutions of both adapters were used with 18 amplification cycles (TriLink BioTechnologies). Fragments between 140-170bp were size selected and sequenced on an Illumina HiSeq high output v4 50bp SE in Edinburgh Genomics. Illumina HiSeq 2500 gds 303272805 GSM3272805 GEO Accession GSM3272805 SRX4394660 GSM3272806 SRP153922 PRJNA481340 SRS3549911 SAMN09665780 ncRNA-Seq TRANSCRIPTOMIC size fractionation Total RNA was used directly for library preparation. Total RNA was extracted using a miRNAeasy mini kit (Qiagen) following manufacturer's instructions. RNA was treated with Turbo DNA-free kit (Thermo Fisher) to remove residual DNA. Libraries were prepared using the CleanTag small RNA library prep kit according to manufacturer's instructions, using total RNA from adult worms (30 ng), and sucrose-gradient purified EVs (equivalent 1E10 EVs measured by Nanosight, Malvern). For all samples, 1:12 dilutions of both adapters were used with 18 amplification cycles (TriLink BioTechnologies). Fragments between 140-170bp were size selected and sequenced on an Illumina HiSeq high output v4 50bp SE in Edinburgh Genomics. Illumina HiSeq 2500 gds 303272806 GSM3272806 GEO Accession GSM3272806 SRX4394661 GSM3272807 SRP153922 PRJNA481340 SRS3549912 SAMN09665773 ncRNA-Seq TRANSCRIPTOMIC size fractionation Total RNA was used directly for library preparation. Total RNA was extracted using a miRNAeasy mini kit (Qiagen) following manufacturer's instructions. RNA was treated with Turbo DNA-free kit (Thermo Fisher) to remove residual DNA. Libraries were prepared using the CleanTag small RNA library prep kit according to manufacturer's instructions, using total RNA from adult worms (30 ng), and sucrose-gradient purified EVs (equivalent 1E10 EVs measured by Nanosight, Malvern). For all samples, 1:12 dilutions of both adapters were used with 18 amplification cycles (TriLink BioTechnologies). Fragments between 140-170bp were size selected and sequenced on an Illumina HiSeq high output v4 50bp SE in Edinburgh Genomics. Illumina HiSeq 2500 gds 303272807 GSM3272807 GEO Accession GSM3272807 SRX4394662 GSM3272808 SRP153922 PRJNA481340 SRS3549913 SAMN09665767 ncRNA-Seq TRANSCRIPTOMIC size fractionation Total RNA was treated with RNA 5' Polyphosphatase (Epicenter) following manufacturer's instructions, before library preparation. Total RNA was extracted using a miRNAeasy mini kit (Qiagen) following manufacturer's instructions. RNA was treated with Turbo DNA-free kit (Thermo Fisher) to remove residual DNA. Libraries were prepared using the CleanTag small RNA library prep kit according to manufacturer's instructions, using total RNA from adult worms (30 ng), and sucrose-gradient purified EVs (equivalent 1E10 EVs measured by Nanosight, Malvern). For all samples, 1:12 dilutions of both adapters were used with 18 amplification cycles (TriLink BioTechnologies). Fragments between 140-170bp were size selected and sequenced on an Illumina HiSeq high output v4 50bp SE in Edinburgh Genomics. Illumina HiSeq 2500 gds 303272808 GSM3272808 GEO Accession GSM3272808 SRX4394663 GSM3272809 SRP153922 PRJNA481340 SRS3549914 SAMN09665764 ncRNA-Seq TRANSCRIPTOMIC size fractionation Total RNA was treated with RNA 5' Polyphosphatase (Epicenter) following manufacturer's instructions, before library preparation. Total RNA was extracted using a miRNAeasy mini kit (Qiagen) following manufacturer's instructions. RNA was treated with Turbo DNA-free kit (Thermo Fisher) to remove residual DNA. Libraries were prepared using the CleanTag small RNA library prep kit according to manufacturer's instructions, using total RNA from adult worms (30 ng), and sucrose-gradient purified EVs (equivalent 1E10 EVs measured by Nanosight, Malvern). For all samples, 1:12 dilutions of both adapters were used with 18 amplification cycles (TriLink BioTechnologies). Fragments between 140-170bp were size selected and sequenced on an Illumina HiSeq high output v4 50bp SE in Edinburgh Genomics. Illumina HiSeq 2500 gds 303272809 GSM3272809 GEO Accession GSM3272809 SRX4394664 GSM3272810 SRP153922 PRJNA481340 SRS3549915 SAMN09665763 ncRNA-Seq TRANSCRIPTOMIC size fractionation Total RNA was treated with RNA 5' Polyphosphatase (Epicenter) following manufacturer's instructions, before library preparation. Total RNA was extracted using a miRNAeasy mini kit (Qiagen) following manufacturer's instructions. RNA was treated with Turbo DNA-free kit (Thermo Fisher) to remove residual DNA. Libraries were prepared using the CleanTag small RNA library prep kit according to manufacturer's instructions, using total RNA from adult worms (30 ng), and sucrose-gradient purified EVs (equivalent 1E10 EVs measured by Nanosight, Malvern). For all samples, 1:12 dilutions of both adapters were used with 18 amplification cycles (TriLink BioTechnologies). Fragments between 140-170bp were size selected and sequenced on an Illumina HiSeq high output v4 50bp SE in Edinburgh Genomics. Illumina HiSeq 2500 gds 303272810 GSM3272810 GEO Accession GSM3272810 SRX4394665 GSM3272811 SRP153922 PRJNA481340 SRS3549916 SAMN09665762 ncRNA-Seq TRANSCRIPTOMIC size fractionation Total RNA was treated with RNA 5' Polyphosphatase (Epicenter) following manufacturer's instructions, before library preparation. Total RNA was extracted using a miRNAeasy mini kit (Qiagen) following manufacturer's instructions. RNA was treated with Turbo DNA-free kit (Thermo Fisher) to remove residual DNA. Libraries were prepared using the CleanTag small RNA library prep kit according to manufacturer's instructions, using total RNA from adult worms (30 ng), and sucrose-gradient purified EVs (equivalent 1E10 EVs measured by Nanosight, Malvern). For all samples, 1:12 dilutions of both adapters were used with 18 amplification cycles (TriLink BioTechnologies). Fragments between 140-170bp were size selected and sequenced on an Illumina HiSeq high output v4 50bp SE in Edinburgh Genomics. Illumina HiSeq 2500 gds 303272811 GSM3272811 GEO Accession GSM3272811 SRX4394666 GSM3272812 SRP153922 PRJNA481340 SRS3549917 SAMN09665761 ncRNA-Seq TRANSCRIPTOMIC size fractionation Total RNA was treated with RNA 5' Polyphosphatase (Epicenter) following manufacturer's instructions, before library preparation. Total RNA was extracted using a miRNAeasy mini kit (Qiagen) following manufacturer's instructions. RNA was treated with Turbo DNA-free kit (Thermo Fisher) to remove residual DNA. Libraries were prepared using the CleanTag small RNA library prep kit according to manufacturer's instructions, using total RNA from adult worms (30 ng), and sucrose-gradient purified EVs (equivalent 1E10 EVs measured by Nanosight, Malvern). For all samples, 1:12 dilutions of both adapters were used with 18 amplification cycles (TriLink BioTechnologies). Fragments between 140-170bp were size selected and sequenced on an Illumina HiSeq high output v4 50bp SE in Edinburgh Genomics. Illumina HiSeq 2500 gds 303272812 GSM3272812 GEO Accession GSM3272812 SRX4394667 GSM3272813 SRP153922 PRJNA481340 SRS3549919 SAMN09665760 ncRNA-Seq TRANSCRIPTOMIC size fractionation Total RNA was treated with RNA 5' Polyphosphatase (Epicenter) following manufacturer's instructions, before library preparation. Total RNA was extracted using a miRNAeasy mini kit (Qiagen) following manufacturer's instructions. RNA was treated with Turbo DNA-free kit (Thermo Fisher) to remove residual DNA. Libraries were prepared using the CleanTag small RNA library prep kit according to manufacturer's instructions, using total RNA from adult worms (30 ng), and sucrose-gradient purified EVs (equivalent 1E10 EVs measured by Nanosight, Malvern). For all samples, 1:12 dilutions of both adapters were used with 18 amplification cycles (TriLink BioTechnologies). Fragments between 140-170bp were size selected and sequenced on an Illumina HiSeq high output v4 50bp SE in Edinburgh Genomics. Illumina HiSeq 2500 gds 303272813 GSM3272813 GEO Accession GSM3272813 SRX4394668 GSM3272814 SRP153922 PRJNA481340 SRS3549918 SAMN09665759 ncRNA-Seq TRANSCRIPTOMIC size fractionation Total RNA was used directly for library preparation. Total RNA was extracted using a miRNAeasy mini kit (Qiagen) following manufacturer's instructions. RNA was treated with Turbo DNA-free kit (Thermo Fisher) to remove residual DNA. Libraries were prepared using the CleanTag small RNA library prep kit according to manufacturer's instructions, using total RNA from adult worms (30 ng), and sucrose-gradient purified EVs (equivalent 1E10 EVs measured by Nanosight, Malvern). For all samples, 1:12 dilutions of both adapters were used with 18 amplification cycles (TriLink BioTechnologies). Fragments between 140-170bp were size selected and sequenced on an Illumina HiSeq high output v4 50bp SE in Edinburgh Genomics. Illumina HiSeq 2500 gds 303272814 GSM3272814 GEO Accession GSM3272814 SRX4394669 GSM3272815 SRP153922 PRJNA481340 SRS3549920 SAMN09665758 ncRNA-Seq TRANSCRIPTOMIC size fractionation Total RNA was used directly for library preparation. Total RNA was extracted using a miRNAeasy mini kit (Qiagen) following manufacturer's instructions. RNA was treated with Turbo DNA-free kit (Thermo Fisher) to remove residual DNA. Libraries were prepared using the CleanTag small RNA library prep kit according to manufacturer's instructions, using total RNA from adult worms (30 ng), and sucrose-gradient purified EVs (equivalent 1E10 EVs measured by Nanosight, Malvern). For all samples, 1:12 dilutions of both adapters were used with 18 amplification cycles (TriLink BioTechnologies). Fragments between 140-170bp were size selected and sequenced on an Illumina HiSeq high output v4 50bp SE in Edinburgh Genomics. Illumina HiSeq 2500 gds 303272815 GSM3272815 GEO Accession GSM3272815 SRX4394670 GSM3272816 SRP153922 PRJNA481340 SRS3549922 SAMN09665757 ncRNA-Seq TRANSCRIPTOMIC size fractionation Total RNA was used directly for library preparation. Total RNA was extracted using a miRNAeasy mini kit (Qiagen) following manufacturer's instructions. RNA was treated with Turbo DNA-free kit (Thermo Fisher) to remove residual DNA. Libraries were prepared using the CleanTag small RNA library prep kit according to manufacturer's instructions, using total RNA from adult worms (30 ng), and sucrose-gradient purified EVs (equivalent 1E10 EVs measured by Nanosight, Malvern). For all samples, 1:12 dilutions of both adapters were used with 18 amplification cycles (TriLink BioTechnologies). Fragments between 140-170bp were size selected and sequenced on an Illumina HiSeq high output v4 50bp SE in Edinburgh Genomics. Illumina HiSeq 2500 gds 303272816 GSM3272816 GEO Accession GSM3272816 SRX4394671 GSM3272817 SRP153922 PRJNA481340 SRS3549921 SAMN09665756 ncRNA-Seq TRANSCRIPTOMIC size fractionation Total RNA was treated with RNA 5' Polyphosphatase (Epicenter) following manufacturer's instructions, before library preparation. Total RNA was extracted using a miRNAeasy mini kit (Qiagen) following manufacturer's instructions. RNA was treated with Turbo DNA-free kit (Thermo Fisher) to remove residual DNA. Libraries were prepared using the CleanTag small RNA library prep kit according to manufacturer's instructions, using total RNA from adult worms (30 ng), and sucrose-gradient purified EVs (equivalent 1E10 EVs measured by Nanosight, Malvern). For all samples, 1:12 dilutions of both adapters were used with 18 amplification cycles (TriLink BioTechnologies). Fragments between 140-170bp were size selected and sequenced on an Illumina HiSeq high output v4 50bp SE in Edinburgh Genomics. Illumina HiSeq 2500 gds 303272817 GSM3272817 GEO Accession GSM3272817 SRX4394672 GSM3272818 SRP153922 PRJNA481340 SRS3549923 SAMN09665755 ncRNA-Seq TRANSCRIPTOMIC size fractionation Total RNA was treated with RNA 5' Polyphosphatase (Epicenter) following manufacturer's instructions, before library preparation. Total RNA was extracted using a miRNAeasy mini kit (Qiagen) following manufacturer's instructions. RNA was treated with Turbo DNA-free kit (Thermo Fisher) to remove residual DNA. Libraries were prepared using the CleanTag small RNA library prep kit according to manufacturer's instructions, using total RNA from adult worms (30 ng), and sucrose-gradient purified EVs (equivalent 1E10 EVs measured by Nanosight, Malvern). For all samples, 1:12 dilutions of both adapters were used with 18 amplification cycles (TriLink BioTechnologies). Fragments between 140-170bp were size selected and sequenced on an Illumina HiSeq high output v4 50bp SE in Edinburgh Genomics. Illumina HiSeq 2500 gds 303272818 GSM3272818 GEO Accession GSM3272818 SRX4394673 GSM3272819 SRP153922 PRJNA481340 SRS3549924 SAMN09665754 ncRNA-Seq TRANSCRIPTOMIC size fractionation Total RNA was treated with RNA 5' Polyphosphatase (Epicenter) following manufacturer's instructions, before library preparation. Total RNA was extracted using a miRNAeasy mini kit (Qiagen) following manufacturer's instructions. RNA was treated with Turbo DNA-free kit (Thermo Fisher) to remove residual DNA. Libraries were prepared using the CleanTag small RNA library prep kit according to manufacturer's instructions, using total RNA from adult worms (30 ng), and sucrose-gradient purified EVs (equivalent 1E10 EVs measured by Nanosight, Malvern). For all samples, 1:12 dilutions of both adapters were used with 18 amplification cycles (TriLink BioTechnologies). Fragments between 140-170bp were size selected and sequenced on an Illumina HiSeq high output v4 50bp SE in Edinburgh Genomics. Illumina HiSeq 2500 gds 303272819 GSM3272819 GEO Accession GSM3272819