<?xml version="1.0" encoding="UTF-8"?>
<STUDY_SET xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <STUDY center_name="GEO" alias="GSE118143" accession="SRP156429">
    <IDENTIFIERS>
      <PRIMARY_ID>SRP156429</PRIMARY_ID>
      <EXTERNAL_ID namespace="BioProject" label="primary">PRJNA484699</EXTERNAL_ID>
      <EXTERNAL_ID namespace="GEO">GSE118143</EXTERNAL_ID>
    </IDENTIFIERS>
    <DESCRIPTOR>
      <STUDY_TITLE>Transcriptome sequencing of A.thaliana leaves after exposure to silver nanoparticles.</STUDY_TITLE>
      <STUDY_TYPE existing_study_type="Transcriptome Analysis"/>
      <STUDY_ABSTRACT>RNA-Seq analysis was used for deep sequencing of transcriptome to detected molecular mechanisms of silver nanoparticles (AgNPs) and distinguish the effects of Arabidopsis thaliana exposure to AgNPs and Ag+.We identified 626 and 767 differentially expressed genes (DEGs) influenced by AgNPs and Ag+ respectively.302 genes were specifically regulated by the AgNPs treatment indicates that the  nanoparticle-specific effects.This study provide a valuable resource for the discovery of genes related to special toxicity mechanism of AgNPs. Overall design: Transcriptome of nine A.thaliana leaves were generated by deep sequencing using Illumina.</STUDY_ABSTRACT>
      <CENTER_PROJECT_NAME>GSE118143</CENTER_PROJECT_NAME>
    </DESCRIPTOR>
  </STUDY>
</STUDY_SET>
