SRP172671 PRJNA508601 GSE123380 Overexpression of Claspin and Timeless protects cancer cells from replication stress in a checkpoint-independent manner RNA-seq analysis of BJ cells overexpressing RasV12 and escaping senescence Overall design: Immortalized BJ-hTERT cells expressing an oncogenic version of Ras under the control of a doxycyclin-inducible promoter were grown for 60 days in the presence of Dox to induce oncogene-induced senescence (OIS). Three individual clones escaping senescence were isolated and were analyzed by RNA-seq. GSE123380 pubmed 30796221