SRX5177040 GSM3528852 SRP174368 SRS4184312 GSM3528852 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA from three types of constructs was purified using the RNAeasy Mini Kit (Qiagen) and residual DNA was removed by on-column DNase digestion. RNA quality was assessed with the Agilent RNA 6000 Nano Kit using the Agilent 2100 Bioanalyzer (Agilent Technologies). Only samples with RNA integrity number higher than 8 were kept for further analysis. RNA sequencing was performed on poly-A-enriched samples using Illumina TruSeq RNA libraries were prepared for sequencing using standard Illumina protocols Illumina HiSeq 2500 gds 303528852 GSM3528852 GEO Accession GSM3528852 SRX5177041 GSM3528853 SRP174368 SRS4184313 GSM3528853 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA from three types of constructs was purified using the RNAeasy Mini Kit (Qiagen) and residual DNA was removed by on-column DNase digestion. RNA quality was assessed with the Agilent RNA 6000 Nano Kit using the Agilent 2100 Bioanalyzer (Agilent Technologies). Only samples with RNA integrity number higher than 8 were kept for further analysis. RNA sequencing was performed on poly-A-enriched samples using Illumina TruSeq RNA libraries were prepared for sequencing using standard Illumina protocols Illumina HiSeq 2500 gds 303528853 GSM3528853 GEO Accession GSM3528853 SRX5177042 GSM3528854 SRP174368 SRS4184314 GSM3528854 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA from three types of constructs was purified using the RNAeasy Mini Kit (Qiagen) and residual DNA was removed by on-column DNase digestion. RNA quality was assessed with the Agilent RNA 6000 Nano Kit using the Agilent 2100 Bioanalyzer (Agilent Technologies). Only samples with RNA integrity number higher than 8 were kept for further analysis. RNA sequencing was performed on poly-A-enriched samples using Illumina TruSeq RNA libraries were prepared for sequencing using standard Illumina protocols Illumina HiSeq 2500 gds 303528854 GSM3528854 GEO Accession GSM3528854 SRX5177043 GSM3528855 SRP174368 SRS4184315 GSM3528855 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA from three types of constructs was purified using the RNAeasy Mini Kit (Qiagen) and residual DNA was removed by on-column DNase digestion. RNA quality was assessed with the Agilent RNA 6000 Nano Kit using the Agilent 2100 Bioanalyzer (Agilent Technologies). Only samples with RNA integrity number higher than 8 were kept for further analysis. RNA sequencing was performed on poly-A-enriched samples using Illumina TruSeq RNA libraries were prepared for sequencing using standard Illumina protocols Illumina HiSeq 2500 gds 303528855 GSM3528855 GEO Accession GSM3528855 SRX5177044 GSM3528856 SRP174368 SRS4184316 GSM3528856 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA from three types of constructs was purified using the RNAeasy Mini Kit (Qiagen) and residual DNA was removed by on-column DNase digestion. RNA quality was assessed with the Agilent RNA 6000 Nano Kit using the Agilent 2100 Bioanalyzer (Agilent Technologies). Only samples with RNA integrity number higher than 8 were kept for further analysis. RNA sequencing was performed on poly-A-enriched samples using Illumina TruSeq RNA libraries were prepared for sequencing using standard Illumina protocols Illumina HiSeq 2500 gds 303528856 GSM3528856 GEO Accession GSM3528856 SRX5177045 GSM3528857 SRP174368 SRS4184317 GSM3528857 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA from three types of constructs was purified using the RNAeasy Mini Kit (Qiagen) and residual DNA was removed by on-column DNase digestion. RNA quality was assessed with the Agilent RNA 6000 Nano Kit using the Agilent 2100 Bioanalyzer (Agilent Technologies). Only samples with RNA integrity number higher than 8 were kept for further analysis. RNA sequencing was performed on poly-A-enriched samples using Illumina TruSeq RNA libraries were prepared for sequencing using standard Illumina protocols Illumina HiSeq 2500 gds 303528857 GSM3528857 GEO Accession GSM3528857