SRS4190644 SAMN10636480 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.031 host_residential_stratification LongStay treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 81 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 17 host_body_mass_index 47.1 collection_date 2015-10-22 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 47.1 Weight (kg) 133 Appendix A - Charlson co-morbidity 4 Appendix B - Barthel Score 17 Appendix C - FIM 119 Alkaline Phosphatase 81 ALT 30 AST 17 Billirubin 7 Cholesterol 4.8 High Density Lipoprotein(HDL) 1.1 Low Density Lipoprotein (LDL) 2.9 Triglycerides 1.69 Glucose 6.4 Creatinine 170 Ferritin 43 Thyroid Stimulating Hormone (TSH) 2.34 Urea 13 Vitamin B12 145 White blood cells 12 HFD_index 0.480899539910355 CRP (mg/L) 16 CXCL11 (pg/ml) 0 CCL11 (pg/ml) 645.561019467376 IL17A (pg/ml) 1.84257111315288 IFN-gamma (pg/ml) 5.47270466657013 IL-10 (pg/ml) 0.424279648550982 IL-6 (pg/ml) 4.10445933838621 IL-8 (pg/ml) 16.4435141514744 TNF-alpha (pg/ml) 3.38069704592517 CD4 (%) 34.4 CD8 (%) 16.2 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190645 SAMN10636304 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.003 host_residential_stratification Community treatment Placebo time_point week13 host Homo sapiens isolate Stool age not applicable host_age 75 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 25.8 collection_date 2016-02-04 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 25.8 Weight (kg) 66 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 81 ALT 14 AST 24 Billirubin 10 Cholesterol 5.4 High Density Lipoprotein(HDL) 1.4 Low Density Lipoprotein (LDL) 3.4 Triglycerides 1.28 Glucose 5.4 Creatinine 43 Ferritin 168 Thyroid Stimulating Hormone (TSH) 1.44 Urea 3.7 Vitamin B12 409 White blood cells 7.6 HFD_index 0.400252235883184 CRP (mg/L) 0.6 CXCL11 (pg/ml) 139.296941745369 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.726864415281624 IFN-gamma (pg/ml) 2.33344206640289 IL-10 (pg/ml) 0.0401393250847758 IL-6 (pg/ml) 0.255664121566862 IL-8 (pg/ml) 4.8891120779429 TNF-alpha (pg/ml) 0.86619038007684 CD4 (%) 36.7 CD8 (%) 10.9 LPS (EU/ml) 30.8546849136222 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190646 SAMN10636482 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.031 host_residential_stratification LongStay treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 81 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 18 host_body_mass_index 47.5 collection_date 2016-02-28 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 47.5 Weight (kg) 134.1 Appendix A - Charlson co-morbidity 4 Appendix B - Barthel Score 18 Appendix C - FIM 115 Alkaline Phosphatase 52 ALT 87 AST 31 Billirubin 8 Cholesterol 5 High Density Lipoprotein(HDL) 1.48 Low Density Lipoprotein (LDL) 2.5 Triglycerides 2.26 Glucose 4.5 Creatinine 166 Ferritin 69 Thyroid Stimulating Hormone (TSH) 1.34 Urea 19.9 Vitamin B12 218 White blood cells 11.3 HFD_index 0.464642023027856 CRP (mg/L) 3.1 CXCL11 (pg/ml) 0 CCL11 (pg/ml) 713.816982074622 IL17A (pg/ml) 12.9869121675235 IFN-gamma (pg/ml) 3.71638179109273 IL-10 (pg/ml) 1.1761068615657 IL-6 (pg/ml) 1.49004781039441 IL-8 (pg/ml) 30.5399179339569 TNF-alpha (pg/ml) 3.19203620538544 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 0.147471910112359 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190647 SAMN10636479 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.031 host_residential_stratification LongStay treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 81 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 17 host_body_mass_index 46.9 collection_date 2016-07-21 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 46.9 Weight (kg) 132.5 Appendix A - Charlson co-morbidity 4 Appendix B - Barthel Score 17 Appendix C - FIM 119 Alkaline Phosphatase 70 ALT 28 AST 15 Billirubin 5 Cholesterol 4.3 High Density Lipoprotein(HDL) 1.2 Low Density Lipoprotein (LDL) 2.4 Triglycerides 1.57 Glucose 3.9 Creatinine 175 Ferritin 16 Thyroid Stimulating Hormone (TSH) 2.03 Urea 15.5 Vitamin B12 141 White blood cells 13.9 HFD_index not collected CRP (mg/L) 15.6 CXCL11 (pg/ml) 174.231687528162 CCL11 (pg/ml) 527.575031466962 IL17A (pg/ml) 4.77649774351577 IFN-gamma (pg/ml) 2.08005827600825 IL-10 (pg/ml) 0.61307955876657 IL-6 (pg/ml) 1.94269473331127 IL-8 (pg/ml) 16.3791467855712 TNF-alpha (pg/ml) 3.46350985163577 CD4 (%) 5.3 CD8 (%) 10.8 LPS (EU/ml) 7.18852459016393 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190648 SAMN10636481 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.031 host_residential_stratification LongStay treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 81 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 18 host_body_mass_index 46.8 collection_date 2016-01-25 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 46.8 Weight (kg) 132 Appendix A - Charlson co-morbidity 4 Appendix B - Barthel Score 18 Appendix C - FIM 115 Alkaline Phosphatase 48 ALT 119 AST 36 Billirubin 8 Cholesterol 6.9 High Density Lipoprotein(HDL) 1.42 Low Density Lipoprotein (LDL) 3.8 Triglycerides 3.7 Glucose 5.4 Creatinine 194 Ferritin not collected Thyroid Stimulating Hormone (TSH) 0.75 Urea 22 Vitamin B12 not collected White blood cells not collected HFD_index 0.464642023027856 CRP (mg/L) 4 CXCL11 (pg/ml) 0 CCL11 (pg/ml) 627.34316566512 IL17A (pg/ml) 0.388544148210009 IFN-gamma (pg/ml) 1.45115091296093 IL-10 (pg/ml) 0.562989271346669 IL-6 (pg/ml) 1.21737038575454 IL-8 (pg/ml) 20.5426992964511 TNF-alpha (pg/ml) 2.96844821275117 CD4 (%) 53.8 CD8 (%) 17.6 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190649 SAMN10636476 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.029 host_residential_stratification LongStay treatment Placebo time_point week32 host Homo sapiens isolate Stool age not applicable host_age 95 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 1 host_body_mass_index 23.4 collection_date 2016-01-14 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23.4 Weight (kg) 57.8 Appendix A - Charlson co-morbidity 2 Appendix B - Barthel Score 1 Appendix C - FIM 38 Alkaline Phosphatase not collected ALT not collected AST not collected Billirubin not collected Cholesterol not collected High Density Lipoprotein(HDL) not collected Low Density Lipoprotein (LDL) not collected Triglycerides not collected Glucose not collected Creatinine not collected Ferritin not collected Thyroid Stimulating Hormone (TSH) not collected Urea not collected Vitamin B12 not collected White blood cells not collected HFD_index 0.282453940836008 CRP (mg/L) not collected CXCL11 (pg/ml) not collected CCL11 (pg/ml) not collected IL17A (pg/ml) not collected IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190650 SAMN10636475 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.029 host_residential_stratification LongStay treatment Placebo time_point week26 host Homo sapiens isolate Stool age not applicable host_age 95 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 1 host_body_mass_index 23.28 collection_date 2015-11-18 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23.28 Weight (kg) 57.4 Appendix A - Charlson co-morbidity 2 Appendix B - Barthel Score 1 Appendix C - FIM 38 Alkaline Phosphatase not collected ALT not collected AST not collected Billirubin not collected Cholesterol not collected High Density Lipoprotein(HDL) not collected Low Density Lipoprotein (LDL) not collected Triglycerides not collected Glucose not collected Creatinine not collected Ferritin not collected Thyroid Stimulating Hormone (TSH) not collected Urea not collected Vitamin B12 not collected White blood cells not collected HFD_index 0.283724062752892 CRP (mg/L) not collected CXCL11 (pg/ml) not collected CCL11 (pg/ml) not collected IL17A (pg/ml) not collected IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190651 SAMN10636478 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.030 host_residential_stratification LongStay treatment Placebo time_point week26 host Homo sapiens isolate Stool age not applicable host_age 83 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 1 host_body_mass_index 22.1 collection_date 2015-11-20 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 22.1 Weight (kg) 61.2 Appendix A - Charlson co-morbidity 3 Appendix B - Barthel Score 1 Appendix C - FIM 42 Alkaline Phosphatase not collected ALT not collected AST not collected Billirubin not collected Cholesterol not collected High Density Lipoprotein(HDL) not collected Low Density Lipoprotein (LDL) not collected Triglycerides not collected Glucose not collected Creatinine not collected Ferritin not collected Thyroid Stimulating Hormone (TSH) not collected Urea not collected Vitamin B12 not collected White blood cells not collected HFD_index 0.299270886374261 CRP (mg/L) not collected CXCL11 (pg/ml) not collected CCL11 (pg/ml) not collected IL17A (pg/ml) not collected IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190652 SAMN10636477 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.030 host_residential_stratification LongStay treatment Placebo time_point week13 host Homo sapiens isolate Stool age not applicable host_age 82 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 1 host_body_mass_index 23.6 collection_date 2015-08-21 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23.6 Weight (kg) 64.2 Appendix A - Charlson co-morbidity 3 Appendix B - Barthel Score 1 Appendix C - FIM 42 Alkaline Phosphatase not collected ALT not collected AST not collected Billirubin not collected Cholesterol not collected High Density Lipoprotein(HDL) not collected Low Density Lipoprotein (LDL) not collected Triglycerides not collected Glucose not collected Creatinine not collected Ferritin not collected Thyroid Stimulating Hormone (TSH) not collected Urea not collected Vitamin B12 not collected White blood cells not collected HFD_index 0.299270886374261 CRP (mg/L) not collected CXCL11 (pg/ml) not collected CCL11 (pg/ml) not collected IL17A (pg/ml) not collected IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) 52.7 CD8 (%) 17.3 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190653 SAMN10636542 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.022 host_residential_stratification YoungHealthy treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 33 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 22.8 collection_date 2016-08-18 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 22.8 Weight (kg) 78 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 61 ALT 35 AST 27 Billirubin 10 Cholesterol 5.2 High Density Lipoprotein(HDL) 1.55 Low Density Lipoprotein (LDL) 3.4 Triglycerides 0.62 Glucose 5.1 Creatinine 101 Ferritin 93 Thyroid Stimulating Hormone (TSH) 1.12 Urea 5.2 Vitamin B12 1500 White blood cells 4.7 HFD_index 0.451666308448942 CRP (mg/L) 1 CXCL11 (pg/ml) 61.2259241918567 CCL11 (pg/ml) 8.25908080092816 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 2.66832708997971 IL-10 (pg/ml) 0.0634429304623028 IL-6 (pg/ml) 0.0856409162169285 IL-8 (pg/ml) 9.82394872964484 TNF-alpha (pg/ml) 1.93682703240053 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 5.31147540983606 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190654 SAMN10636574 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.032 host_residential_stratification YoungHealthy treatment Placebo time_point week0 host Homo sapiens isolate Stool age not applicable host_age 31 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 30.7 collection_date 2016-03-10 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 30.7 Weight (kg) 95 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 78 ALT 32 AST 29 Billirubin 10 Cholesterol 5.7 High Density Lipoprotein(HDL) 1.14 Low Density Lipoprotein (LDL) 4.1 Triglycerides 1.02 Glucose 5.3 Creatinine 86 Ferritin 44 Thyroid Stimulating Hormone (TSH) 1.94 Urea 4.6 Vitamin B12 258 White blood cells 8.3 HFD_index 0.327326474175181 CRP (mg/L) 0.3 CXCL11 (pg/ml) not collected CCL11 (pg/ml) not collected IL17A (pg/ml) not collected IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) 31.5 CD8 (%) 26.4 LPS (EU/ml) 18.462918660287 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190655 SAMN10636573 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.031 host_residential_stratification YoungHealthy treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 62 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 29.1 collection_date 2016-09-23 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 29.1 Weight (kg) 83 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase not collected ALT not collected AST not collected Billirubin not collected Cholesterol not collected High Density Lipoprotein(HDL) not collected Low Density Lipoprotein (LDL) not collected Triglycerides not collected Glucose 3.8 Creatinine not collected Ferritin 26 Thyroid Stimulating Hormone (TSH) not collected Urea not collected Vitamin B12 297 White blood cells 3.5 HFD_index 0.481946928256171 CRP (mg/L) not collected CXCL11 (pg/ml) not collected CCL11 (pg/ml) not collected IL17A (pg/ml) not collected IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 18.9114832535885 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190656 SAMN10636484 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.001 host_residential_stratification YoungHealthy treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 27 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 19.9 collection_date 2016-01-08 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 19.9 Weight (kg) 66 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 60 ALT 19 AST 20 Billirubin 11 Cholesterol 6.4 High Density Lipoprotein(HDL) 1.2 Low Density Lipoprotein (LDL) 4.7 Triglycerides 1.17 Glucose 5.1 Creatinine 78 Ferritin 25 Thyroid Stimulating Hormone (TSH) 3.91 Urea 5 Vitamin B12 181 White blood cells 6.1 HFD_index 0.461664072944645 CRP (mg/L) 0.1 CXCL11 (pg/ml) 19.6136139079685 CCL11 (pg/ml) 4.11364341193147 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 2.58985538651664 IL-10 (pg/ml) 0.0840990811998694 IL-6 (pg/ml) 0 IL-8 (pg/ml) 4.08028258299559 TNF-alpha (pg/ml) 0.301007862078256 CD4 (%) 20 CD8 (%) 15.4 LPS (EU/ml) 20.5931037698459 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190657 SAMN10636483 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.001 host_residential_stratification YoungHealthy treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 27 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 20.8 collection_date 2015-10-08 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 20.8 Weight (kg) 69 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 67 ALT 18 AST 20 Billirubin 8 Cholesterol 6.2 High Density Lipoprotein(HDL) 1.09 Low Density Lipoprotein (LDL) 4.2 Triglycerides 2.01 Glucose 3.3 Creatinine 84 Ferritin 28 Thyroid Stimulating Hormone (TSH) 1.6 Urea 5.4 Vitamin B12 201 White blood cells 5.4 HFD_index 0.46776769636899 CRP (mg/L) 2.5 CXCL11 (pg/ml) 21.2377796295462 CCL11 (pg/ml) 8.38018175426003 IL17A (pg/ml) 3.71389630096985e-08 IFN-gamma (pg/ml) 5.42529980123726 IL-10 (pg/ml) 0.132586256483451 IL-6 (pg/ml) 0.215764428232061 IL-8 (pg/ml) 7.2157941669812 TNF-alpha (pg/ml) 0.59567978930122 CD4 (%) 31 CD8 (%) 25.5 LPS (EU/ml) 7.80297107114933 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190658 SAMN10636328 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.009 host_residential_stratification Community treatment Placebo time_point week13 host Homo sapiens isolate Stool age not applicable host_age 77 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 25.8 collection_date 2016-02-19 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 25.8 Weight (kg) 67.8 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 123 Alkaline Phosphatase 56 ALT 30 AST 28 Billirubin 10 Cholesterol 1.66 High Density Lipoprotein(HDL) 1.04 Low Density Lipoprotein (LDL) 1.7 Triglycerides 1.66 Glucose 6.1 Creatinine 84 Ferritin 247 Thyroid Stimulating Hormone (TSH) 2.7 Urea 5.7 Vitamin B12 237 White blood cells 4.7 HFD_index 0.34032393127093 CRP (mg/L) 0.7 CXCL11 (pg/ml) 81.8674108638567 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.97744868373849 IFN-gamma (pg/ml) 5.07088901657821 IL-10 (pg/ml) 0.126285606769154 IL-6 (pg/ml) 0.609916289813957 IL-8 (pg/ml) 12.7455812080737 TNF-alpha (pg/ml) 1.57281735520866 CD4 (%) 21.2 CD8 (%) 10.6 LPS (EU/ml) 11.1124401913875 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190659 SAMN10636536 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.021 host_residential_stratification YoungHealthy treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 64 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 23.3 collection_date 2016-04-26 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23.3 Weight (kg) 78 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 79 ALT 26 AST 29 Billirubin 21 Cholesterol 5.8 High Density Lipoprotein(HDL) 1.4 Low Density Lipoprotein (LDL) 3.8 Triglycerides 1.27 Glucose 5 Creatinine 78 Ferritin 58 Thyroid Stimulating Hormone (TSH) 1.04 Urea 4.6 Vitamin B12 629 White blood cells 7.8 HFD_index 0.408878137620472 CRP (mg/L) 1.6 CXCL11 (pg/ml) 24.625179409381 CCL11 (pg/ml) 7.81592034609444 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 2.80368983006193 IL-10 (pg/ml) 0.0789035866538223 IL-6 (pg/ml) 0.687708335796451 IL-8 (pg/ml) 9.66694694788671 TNF-alpha (pg/ml) 1.75650036102905 CD4 (%) 43.3 CD8 (%) 24.2 LPS (EU/ml) 6.29508196721311 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190660 SAMN10636404 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.030 host_residential_stratification Community treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 66 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 28.4 collection_date 2016-12-14 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 28.4 Weight (kg) 87 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 68 ALT 20 AST 27 Billirubin 11 Cholesterol 6.1 High Density Lipoprotein(HDL) 1.08 Low Density Lipoprotein (LDL) 4.3 Triglycerides 1.42 Glucose 5.3 Creatinine 70 Ferritin 32 Thyroid Stimulating Hormone (TSH) 1.93 Urea 3.7 Vitamin B12 149 White blood cells 3.8 HFD_index 0.577709503811973 CRP (mg/L) 2.5 CXCL11 (pg/ml) 1815.48139243928 CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 2.81277449651895 IL-10 (pg/ml) 0.174286061474493 IL-6 (pg/ml) 0.124814400237073 IL-8 (pg/ml) 16.6739222761583 TNF-alpha (pg/ml) 1.10346655099278 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 3.08009909165978 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190661 SAMN10636403 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.030 host_residential_stratification Community treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 66 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 28.2 collection_date 2016-09-28 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 28.2 Weight (kg) 86.5 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 64 ALT 25 AST 29 Billirubin 12 Cholesterol 6.8 High Density Lipoprotein(HDL) 1.31 Low Density Lipoprotein (LDL) 4.6 Triglycerides 1.99 Glucose 5.1 Creatinine 74 Ferritin 33 Thyroid Stimulating Hormone (TSH) 2.46 Urea 4.4 Vitamin B12 141 White blood cells 4.3 HFD_index 0.537662838943561 CRP (mg/L) 1.3 CXCL11 (pg/ml) 2440.05930322984 CCL11 (pg/ml) 94.4901463357615 IL17A (pg/ml) 0 IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) 42.9 CD8 (%) 13 LPS (EU/ml) 3.57555739058629 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190662 SAMN10636400 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.029 host_residential_stratification Community treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 67 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 23.4 collection_date 2016-12-14 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23.4 Weight (kg) 66 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 90 ALT 22 AST 27 Billirubin 7 Cholesterol 4.6 High Density Lipoprotein(HDL) 1.77 Low Density Lipoprotein (LDL) 2.3 Triglycerides 1.02 Glucose 7.6 Creatinine 61 Ferritin 33 Thyroid Stimulating Hormone (TSH) 0.64 Urea 5.3 Vitamin B12 268 White blood cells 4.9 HFD_index 0.378079470575943 CRP (mg/L) 1.3 CXCL11 (pg/ml) not collected CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 7.15937241948802 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190663 SAMN10636399 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.029 host_residential_stratification Community treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 67 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 23.6 collection_date 2016-09-23 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23.6 Weight (kg) 66.5 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 84 ALT 20 AST 21 Billirubin 6 Cholesterol 4.1 High Density Lipoprotein(HDL) 1.75 Low Density Lipoprotein (LDL) not collected Triglycerides 1.39 Glucose 5.8 Creatinine 68 Ferritin not collected Thyroid Stimulating Hormone (TSH) 0.62 Urea 5.6 Vitamin B12 not collected White blood cells not collected HFD_index 0.401903240576709 CRP (mg/L) 0.7 CXCL11 (pg/ml) not collected CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 1.55968378512431 IL-10 (pg/ml) 0.0594568227025936 IL-6 (pg/ml) 0.315133818102174 IL-8 (pg/ml) 8.85419076370802 TNF-alpha (pg/ml) 0.777630250073134 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 5.54913294797687 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190664 SAMN10636402 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.030 host_residential_stratification Community treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 66 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 28.1 collection_date 2016-06-29 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 28.1 Weight (kg) 86 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 65 ALT 21 AST 30 Billirubin 15 Cholesterol 6.7 High Density Lipoprotein(HDL) 1.22 Low Density Lipoprotein (LDL) 4.9 Triglycerides 1.2 Glucose 5.3 Creatinine 77 Ferritin 34 Thyroid Stimulating Hormone (TSH) 1.6 Urea 5.5 Vitamin B12 140 White blood cells 3.6 HFD_index 0.535616871944617 CRP (mg/L) 1.2 CXCL11 (pg/ml) 2889.62495286431 CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) 30.4 CD8 (%) 7.65 LPS (EU/ml) 3.28654004954582 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190665 SAMN10636401 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.029 host_residential_stratification Community treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 67 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 23.7 collection_date 2017-01-26 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23.7 Weight (kg) 67 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 109 ALT 19 AST 24 Billirubin 7 Cholesterol 4.7 High Density Lipoprotein(HDL) 1.74 Low Density Lipoprotein (LDL) 2.4 Triglycerides 1.36 Glucose 5.4 Creatinine 63 Ferritin 39 Thyroid Stimulating Hormone (TSH) 0.5 Urea 5.1 Vitamin B12 350 White blood cells 5.6 HFD_index 0.378079470575943 CRP (mg/L) 1.2 CXCL11 (pg/ml) not collected CCL11 (pg/ml) not collected IL17A (pg/ml) not collected IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 4.69033856317093 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190666 SAMN10636396 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.028 host_residential_stratification Community treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 73 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 20.7 collection_date 2016-12-13 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 20.7 Weight (kg) 53 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 81 ALT 17 AST 26 Billirubin 6 Cholesterol 5.4 High Density Lipoprotein(HDL) 1.22 Low Density Lipoprotein (LDL) 3.8 Triglycerides 0.89 Glucose 4.3 Creatinine 50 Ferritin 50 Thyroid Stimulating Hormone (TSH) 1.43 Urea 3.1 Vitamin B12 358 White blood cells 4.5 HFD_index 0.595694501633611 CRP (mg/L) 0.4 CXCL11 (pg/ml) not collected CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 5.37607448608059 IL-10 (pg/ml) 0.0771320304592068 IL-6 (pg/ml) 0.382037220781052 IL-8 (pg/ml) 4.76288635243641 TNF-alpha (pg/ml) 1.03618406268051 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 6.41618497109826 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190667 SAMN10636395 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.028 host_residential_stratification Community treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 73 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 19.9 collection_date 2016-09-15 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 19.9 Weight (kg) 51 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 95 ALT 20 AST 31 Billirubin 7 Cholesterol 4.7 High Density Lipoprotein(HDL) 1.07 Low Density Lipoprotein (LDL) 3.2 Triglycerides 0.92 Glucose 4.8 Creatinine 56 Ferritin 57 Thyroid Stimulating Hormone (TSH) 1.37 Urea 3.1 Vitamin B12 326 White blood cells 4.7 HFD_index 0.620940348910055 CRP (mg/L) 0.9 CXCL11 (pg/ml) not collected CCL11 (pg/ml) 87.3194975541172 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 3.3373057141731 IL-10 (pg/ml) 0.0929708859395169 IL-6 (pg/ml) 0.60191006926637 IL-8 (pg/ml) 6.07478285634566 TNF-alpha (pg/ml) 1.20575892911383 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 6.54004954582989 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190668 SAMN10636499 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.006 host_residential_stratification YoungHealthy treatment Placebo time_point week26 host Homo sapiens isolate Stool age not applicable host_age 47 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 26.5 collection_date 2016-04-13 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 26.5 Weight (kg) 84 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 86 ALT 25 AST 30 Billirubin 12 Cholesterol 7.1 High Density Lipoprotein(HDL) 1.12 Low Density Lipoprotein (LDL) 5.1 Triglycerides 1.94 Glucose 4.4 Creatinine 74 Ferritin 133 Thyroid Stimulating Hormone (TSH) 1.69 Urea 3.9 Vitamin B12 175 White blood cells 6.8 HFD_index 0.474250181014963 CRP (mg/L) 2.1 CXCL11 (pg/ml) 0.254574332336039 CCL11 (pg/ml) 4.57746102517428 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 2.20764735830318 IL-10 (pg/ml) 0.0789035866538223 IL-6 (pg/ml) 0.262455664175695 IL-8 (pg/ml) 5.29729071969237 TNF-alpha (pg/ml) 0.260168886237352 CD4 (%) 29.5 CD8 (%) 13.2 LPS (EU/ml) 11.827868852459 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190669 SAMN10636500 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.006 host_residential_stratification YoungHealthy treatment Placebo time_point week32 host Homo sapiens isolate Stool age not applicable host_age 47 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 25.9 collection_date 2016-05-24 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 25.9 Weight (kg) 82 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 88 ALT 26 AST 31 Billirubin 11 Cholesterol 6.9 High Density Lipoprotein(HDL) 1.13 Low Density Lipoprotein (LDL) 4.6 Triglycerides 2.52 Glucose 4.2 Creatinine 69 Ferritin 158 Thyroid Stimulating Hormone (TSH) 1.79 Urea 4.7 Vitamin B12 207 White blood cells 4.8 HFD_index 0.478850299060337 CRP (mg/L) 2.1 CXCL11 (pg/ml) 62.4109908459304 CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 0.0974534960835432 IL-10 (pg/ml) 0.0256901285553139 IL-6 (pg/ml) 0 IL-8 (pg/ml) 0 TNF-alpha (pg/ml) 0 CD4 (%) 46.1 CD8 (%) 13.9 LPS (EU/ml) 6.04918032786885 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190670 SAMN10636497 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.006 host_residential_stratification YoungHealthy treatment Placebo time_point week0 host Homo sapiens isolate Stool age not applicable host_age 46 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 28.7 collection_date 2015-10-16 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 28.7 Weight (kg) 90 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 71 ALT 35 AST 30 Billirubin 7 Cholesterol 7.5 High Density Lipoprotein(HDL) 1.16 Low Density Lipoprotein (LDL) 5.4 Triglycerides 1.93 Glucose 4.2 Creatinine 76 Ferritin 173 Thyroid Stimulating Hormone (TSH) 1.75 Urea 5.1 Vitamin B12 237 White blood cells 5.5 HFD_index 0.430784946105513 CRP (mg/L) 1.5 CXCL11 (pg/ml) 0 CCL11 (pg/ml) 5.20451727082136 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 2.44189448937734 IL-10 (pg/ml) 0.0912142998612022 IL-6 (pg/ml) 0.274700432947012 IL-8 (pg/ml) 7.26379973273268 TNF-alpha (pg/ml) 0.332265470962808 CD4 (%) 37.9 CD8 (%) 15.8 LPS (EU/ml) 5.68032786885245 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190671 SAMN10636498 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.006 host_residential_stratification YoungHealthy treatment Placebo time_point week13 host Homo sapiens isolate Stool age not applicable host_age 47 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 27.3 collection_date 2016-01-14 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 27.3 Weight (kg) 85.5 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 75 ALT 28 AST 24 Billirubin 9 Cholesterol 6.4 High Density Lipoprotein(HDL) 1.17 Low Density Lipoprotein (LDL) 4.7 Triglycerides 1.07 Glucose 4.8 Creatinine 73 Ferritin 95 Thyroid Stimulating Hormone (TSH) 1.34 Urea 4.3 Vitamin B12 209 White blood cells 7.2 HFD_index 0.463553945856253 CRP (mg/L) 1.3 CXCL11 (pg/ml) 0 CCL11 (pg/ml) 3.19178193390776 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 3.65639161399192 IL-10 (pg/ml) 0.118052626183487 IL-6 (pg/ml) 0.331876695390108 IL-8 (pg/ml) 7.13579520751694 TNF-alpha (pg/ml) 0.415014577757815 CD4 (%) 38.5 CD8 (%) 11.4 LPS (EU/ml) 7.64754098360655 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190672 SAMN10636495 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.004 host_residential_stratification YoungHealthy treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 30 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 21.4 collection_date missing env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 21.4 Weight (kg) 62.5 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 45 ALT 17 AST 19 Billirubin 12 Cholesterol 5.7 High Density Lipoprotein(HDL) 1.77 Low Density Lipoprotein (LDL) 3.3 Triglycerides 1.21 Glucose 5.8 Creatinine 64 Ferritin 40 Thyroid Stimulating Hormone (TSH) 3.02 Urea 3.7 Vitamin B12 295 White blood cells 10.9 HFD_index not collected CRP (mg/L) 4.4 CXCL11 (pg/ml) 0 CCL11 (pg/ml) 0.857100486295392 IL17A (pg/ml) 6.27258782288497e-05 IFN-gamma (pg/ml) 6.70591335371293 IL-10 (pg/ml) 0.308610489079257 IL-6 (pg/ml) 0.951683899537426 IL-8 (pg/ml) 7.65293525499263 TNF-alpha (pg/ml) 0.640837982641571 CD4 (%) 48.9 CD8 (%) 10.7 LPS (EU/ml) 20.6349999999999 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190673 SAMN10636496 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.004 host_residential_stratification YoungHealthy treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 31 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 21.9 collection_date 2016-07-14 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 21.9 Weight (kg) 64 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 39 ALT 13 AST 17 Billirubin 10 Cholesterol 5.6 High Density Lipoprotein(HDL) 1.72 Low Density Lipoprotein (LDL) 3.1 Triglycerides 1.66 Glucose 10.9 Creatinine 61 Ferritin 25 Thyroid Stimulating Hormone (TSH) 1.02 Urea 4.7 Vitamin B12 153 White blood cells 6 HFD_index 0.448368655777687 CRP (mg/L) 5.5 CXCL11 (pg/ml) 0.280234941984544 CCL11 (pg/ml) 49.8533363622088 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 5.62746293574202 IL-10 (pg/ml) 0.175241604448873 IL-6 (pg/ml) 0.0673383965899801 IL-8 (pg/ml) 7.2071782730854 TNF-alpha (pg/ml) 0.401296441116116 CD4 (%) 33.5 CD8 (%) 16.6 LPS (EU/ml) 30.82 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190674 SAMN10636425 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.007 host_residential_stratification LongStay treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 71 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 0 host_body_mass_index 23 collection_date 2015-07-23 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23 Weight (kg) 63.4 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 0 Appendix C - FIM 17 Alkaline Phosphatase not collected ALT not collected AST not collected Billirubin not collected Cholesterol not collected High Density Lipoprotein(HDL) not collected Low Density Lipoprotein (LDL) not collected Triglycerides not collected Glucose not collected Creatinine not collected Ferritin not collected Thyroid Stimulating Hormone (TSH) not collected Urea not collected Vitamin B12 not collected White blood cells not collected HFD_index 0.282511992066913 CRP (mg/L) 0 CXCL11 (pg/ml) 109.809262510553 CCL11 (pg/ml) 253.462278555507 IL17A (pg/ml) 4.22012140526323 IFN-gamma (pg/ml) 12.0850370428924 IL-10 (pg/ml) 0.343553236695357 IL-6 (pg/ml) 1.95782111393056 IL-8 (pg/ml) 203.553487964777 TNF-alpha (pg/ml) 7.72548077452272 CD4 (%) 31.5 CD8 (%) 45.6 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190675 SAMN10636426 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.007 host_residential_stratification LongStay treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 72 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 0 host_body_mass_index 23.9 collection_date 2015-09-09 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23.9 Weight (kg) 65.9 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 0 Appendix C - FIM 17 Alkaline Phosphatase 111 ALT 9 AST 17 Billirubin 5 Cholesterol 4.3 High Density Lipoprotein(HDL) 0.91 Low Density Lipoprotein (LDL) 2.8 Triglycerides 1.41 Glucose 7.1 Creatinine 91 Ferritin 107 Thyroid Stimulating Hormone (TSH) 1.29 Urea 7.8 Vitamin B12 224 White blood cells 7.2 HFD_index 0.282511992066913 CRP (mg/L) 55.1 CXCL11 (pg/ml) 860.547551026607 CCL11 (pg/ml) 202.856632381628 IL17A (pg/ml) 2.82889122290914 IFN-gamma (pg/ml) 15.3240192859901 IL-10 (pg/ml) 0.398133560352839 IL-6 (pg/ml) 3.35643733173861 IL-8 (pg/ml) 180.713087062906 TNF-alpha (pg/ml) 8.32656693580922 CD4 (%) 28.9 CD8 (%) 42.3 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190676 SAMN10636428 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.008 host_residential_stratification LongStay treatment Placebo time_point week26 host Homo sapiens isolate Stool age not applicable host_age 91 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 6 host_body_mass_index 29.2 collection_date 2015-07-27 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 29.2 Weight (kg) 103.2 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 6 Appendix C - FIM 69 Alkaline Phosphatase 115 ALT 9 AST 13 Billirubin 7 Cholesterol 4.2 High Density Lipoprotein(HDL) 0.86 Low Density Lipoprotein (LDL) 2.2 Triglycerides 2.46 Glucose 9.2 Creatinine 86 Ferritin 46 Thyroid Stimulating Hormone (TSH) 0.39 Urea 7.7 Vitamin B12 190 White blood cells 7.7 HFD_index 0.261460206202444 CRP (mg/L) 69.5999999999999 CXCL11 (pg/ml) 2045.88302332616 CCL11 (pg/ml) 128.541983910245 IL17A (pg/ml) 0.340942686666844 IFN-gamma (pg/ml) 7.07884380449239 IL-10 (pg/ml) 0.329891370254893 IL-6 (pg/ml) 1.95588021822392 IL-8 (pg/ml) 17.7540246723705 TNF-alpha (pg/ml) 3.83877104892857 CD4 (%) 18.8 CD8 (%) 20.3 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190677 SAMN10636427 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.008 host_residential_stratification LongStay treatment Placebo time_point week13 host Homo sapiens isolate Stool age not applicable host_age 91 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 6 host_body_mass_index 28.8 collection_date 2015-04-23 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 28.8 Weight (kg) 99.5 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 6 Appendix C - FIM 81 Alkaline Phosphatase 104 ALT 11 AST 16 Billirubin 11 Cholesterol 4.2 High Density Lipoprotein(HDL) 0.85 Low Density Lipoprotein (LDL) 2.5 Triglycerides 2.06 Glucose 10.3 Creatinine 87 Ferritin 39 Thyroid Stimulating Hormone (TSH) 0.32 Urea 8.7 Vitamin B12 174 White blood cells 7.7 HFD_index 0.267532707621848 CRP (mg/L) 64.0999999999999 CXCL11 (pg/ml) 2196.92759918253 CCL11 (pg/ml) 198.565233477011 IL17A (pg/ml) 0.369137292139296 IFN-gamma (pg/ml) 6.88478710230771 IL-10 (pg/ml) 0.673188024171954 IL-6 (pg/ml) 3.86009610134441 IL-8 (pg/ml) 15.1135747977372 TNF-alpha (pg/ml) 4.3614618058782 CD4 (%) 9.99 CD8 (%) 15.1 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190678 SAMN10636429 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.008 host_residential_stratification LongStay treatment Placebo time_point week32 host Homo sapiens isolate Stool age not applicable host_age 91 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 6 host_body_mass_index 28.7 collection_date 2015-09-03 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 28.7 Weight (kg) 99.2 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 6 Appendix C - FIM 69 Alkaline Phosphatase 102 ALT 9 AST 13 Billirubin 8 Cholesterol 4 High Density Lipoprotein(HDL) 0.84 Low Density Lipoprotein (LDL) 2.1 Triglycerides 2.36 Glucose 8.9 Creatinine 94 Ferritin 31 Thyroid Stimulating Hormone (TSH) 0.86 Urea 7.1 Vitamin B12 191 White blood cells 8 HFD_index 0.291001590696519 CRP (mg/L) 58.5 CXCL11 (pg/ml) 2427.92476583742 CCL11 (pg/ml) 235.516844637187 IL17A (pg/ml) 0.369137292139296 IFN-gamma (pg/ml) 6.57570442166498 IL-10 (pg/ml) 0.624076078748746 IL-6 (pg/ml) 2.9295295866402 IL-8 (pg/ml) 31.068536840613 TNF-alpha (pg/ml) 4.23793779251434 CD4 (%) 18 CD8 (%) 19.6 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190679 SAMN10636430 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.010 host_residential_stratification LongStay treatment Placebo time_point week0 host Homo sapiens isolate Stool age not applicable host_age 78 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 7 host_body_mass_index 35 collection_date 2015-02-02 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 35 Weight (kg) 125.3 Appendix A - Charlson co-morbidity 2 Appendix B - Barthel Score 7 Appendix C - FIM 60 Alkaline Phosphatase not collected ALT not collected AST not collected Billirubin not collected Cholesterol not collected High Density Lipoprotein(HDL) not collected Low Density Lipoprotein (LDL) not collected Triglycerides not collected Glucose not collected Creatinine not collected Ferritin not collected Thyroid Stimulating Hormone (TSH) not collected Urea not collected Vitamin B12 not collected White blood cells not collected HFD_index not collected CRP (mg/L) 0 CXCL11 (pg/ml) 960.311874482718 CCL11 (pg/ml) 215.432764851998 IL17A (pg/ml) 5.7671762613316 IFN-gamma (pg/ml) 6.76120738334454 IL-10 (pg/ml) 0.222019002990185 IL-6 (pg/ml) 1.08191032216269 IL-8 (pg/ml) 12.1999793784599 TNF-alpha (pg/ml) 3.37426975897626 CD4 (%) 49.5 CD8 (%) 19.6 LPS (EU/ml) 20.6828620054554 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190680 SAMN10636431 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.010 host_residential_stratification LongStay treatment Placebo time_point week13 host Homo sapiens isolate Stool age not applicable host_age 79 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 6 host_body_mass_index 42.9 collection_date 2015-05-26 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 42.9 Weight (kg) 121.1 Appendix A - Charlson co-morbidity 2 Appendix B - Barthel Score 6 Appendix C - FIM 61 Alkaline Phosphatase 149 ALT 12 AST 15 Billirubin 6 Cholesterol 3 High Density Lipoprotein(HDL) 0.85 Low Density Lipoprotein (LDL) 1.4 Triglycerides 1.71 Glucose 7.3 Creatinine 66 Ferritin 190 Thyroid Stimulating Hormone (TSH) 3.65 Urea 6.2 Vitamin B12 218 White blood cells 5.4 HFD_index 0.483648416095847 CRP (mg/L) 13.1 CXCL11 (pg/ml) 923.588706642558 CCL11 (pg/ml) 202.305827562091 IL17A (pg/ml) 0.73344453944941 IFN-gamma (pg/ml) 6.79652304905352 IL-10 (pg/ml) 0.276879702731252 IL-6 (pg/ml) 0.9943537629032 IL-8 (pg/ml) 12.9109088741303 TNF-alpha (pg/ml) 3.64276247740012 CD4 (%) 45.4 CD8 (%) 21.3 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190681 SAMN10636432 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.010 host_residential_stratification LongStay treatment Placebo time_point week26 host Homo sapiens isolate Stool age not applicable host_age 79 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 6 host_body_mass_index 45.9 collection_date 2015-08-20 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 45.9 Weight (kg) 129.5 Appendix A - Charlson co-morbidity 2 Appendix B - Barthel Score 6 Appendix C - FIM 61 Alkaline Phosphatase 142 ALT 11 AST 15 Billirubin 6 Cholesterol 2.8 High Density Lipoprotein(HDL) 0.81 Low Density Lipoprotein (LDL) 1.3 Triglycerides 1.6 Glucose 9.3 Creatinine 72 Ferritin 171 Thyroid Stimulating Hormone (TSH) 3.65 Urea 7 Vitamin B12 193 White blood cells 6.1 HFD_index 0.483648416095847 CRP (mg/L) 24 CXCL11 (pg/ml) 876.346496780862 CCL11 (pg/ml) 196.329510880567 IL17A (pg/ml) 1.59293268020117 IFN-gamma (pg/ml) 6.61105083981797 IL-10 (pg/ml) 0.164395086372884 IL-6 (pg/ml) 1.44296640892205 IL-8 (pg/ml) 15.2850568481248 TNF-alpha (pg/ml) 3.13734202646775 CD4 (%) 39.5 CD8 (%) 20.3 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190682 SAMN10636373 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.022 host_residential_stratification Community treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 68 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 24.8 collection_date 2016-10-12 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.8 Weight (kg) 85.8 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 60 ALT 17 AST 27 Billirubin 12 Cholesterol 5.5 High Density Lipoprotein(HDL) 1.23 Low Density Lipoprotein (LDL) 3.8 Triglycerides 1.16 Glucose 4.8 Creatinine 81 Ferritin 92 Thyroid Stimulating Hormone (TSH) 2.21 Urea 6.3 Vitamin B12 164 White blood cells 4.1 HFD_index 0.320906200445439 CRP (mg/L) 0.8 CXCL11 (pg/ml) 37.3899146356545 CCL11 (pg/ml) 0 IL17A (pg/ml) 1.01141925609136 IFN-gamma (pg/ml) 5.56071930776012 IL-10 (pg/ml) 0.240370971098511 IL-6 (pg/ml) 0.513257306820797 IL-8 (pg/ml) 14.4120750642365 TNF-alpha (pg/ml) 2.27941083485352 CD4 (%) 20 CD8 (%) 4.80999999999999 LPS (EU/ml) 18.5526315789473 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190683 SAMN10636376 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.023 host_residential_stratification Community treatment Placebo time_point week26 host Homo sapiens isolate Stool age not applicable host_age 86 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 28.4 collection_date 2016-10-14 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 28.4 Weight (kg) 83 Appendix A - Charlson co-morbidity 1 Appendix B - Barthel Score 20 Appendix C - FIM 124 Alkaline Phosphatase 77 ALT 29 AST 26 Billirubin 11 Cholesterol 4.4 High Density Lipoprotein(HDL) 1.36 Low Density Lipoprotein (LDL) 1.9 Triglycerides 2.38 Glucose 7.6 Creatinine 110 Ferritin 19 Thyroid Stimulating Hormone (TSH) 1.45 Urea 6.2 Vitamin B12 240 White blood cells 8.5 HFD_index 0.370599404989584 CRP (mg/L) 1.1 CXCL11 (pg/ml) 906.118072231397 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.77609465473701 IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) 16.7 CD8 (%) 13.9 LPS (EU/ml) 12.2488038277511 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190684 SAMN10636565 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.029 host_residential_stratification YoungHealthy treatment Placebo time_point week32 host Homo sapiens isolate Stool age not applicable host_age 22 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 19.8 collection_date 2016-09-27 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 19.8 Weight (kg) 67 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 65 ALT 13 AST 21 Billirubin 11 Cholesterol 5.3 High Density Lipoprotein(HDL) 1.49 Low Density Lipoprotein (LDL) not collected Triglycerides 0.5 Glucose 4.5 Creatinine 90 Ferritin 115 Thyroid Stimulating Hormone (TSH) 0.55 Urea 6.7 Vitamin B12 164 White blood cells 5.8 HFD_index 0.417758443035828 CRP (mg/L) 0.4 CXCL11 (pg/ml) 48.0957259100686 CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 7.18656713370078 IL-10 (pg/ml) 0.124822577501197 IL-6 (pg/ml) 0.0443579995884286 IL-8 (pg/ml) 5.73008654420184 TNF-alpha (pg/ml) 1.392173901092 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 12.6076555023923 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190685 SAMN10636583 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.034 host_residential_stratification YoungHealthy treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 39 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 22.6 collection_date 2016-09-20 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 22.6 Weight (kg) 75 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 91 ALT 15 AST 18 Billirubin 24 Cholesterol 5.7 High Density Lipoprotein(HDL) 1.3 Low Density Lipoprotein (LDL) 2.8 Triglycerides 3.41 Glucose 4 Creatinine 72 Ferritin 71 Thyroid Stimulating Hormone (TSH) 1.8 Urea 5.7 Vitamin B12 215 White blood cells 5.7 HFD_index 0.549466290703554 CRP (mg/L) not collected CXCL11 (pg/ml) not collected CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 0 IL-10 (pg/ml) 0 IL-6 (pg/ml) 0 IL-8 (pg/ml) 0 TNF-alpha (pg/ml) 0 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 5.92072667217175 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190686 SAMN10636584 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.034 host_residential_stratification YoungHealthy treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 40 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 22.3 collection_date 2016-10-20 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 22.3 Weight (kg) 74 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 96 ALT 22 AST 24 Billirubin 40 Cholesterol 5.8 High Density Lipoprotein(HDL) 1.52 Low Density Lipoprotein (LDL) 3.8 Triglycerides 1.16 Glucose 4.2 Creatinine 80 Ferritin 89 Thyroid Stimulating Hormone (TSH) 1.47 Urea 6.1 Vitamin B12 276 White blood cells 5.3 HFD_index 0.555839476067007 CRP (mg/L) 1.1 CXCL11 (pg/ml) not collected CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 0 IL-10 (pg/ml) 0 IL-6 (pg/ml) 0 IL-8 (pg/ml) 0 TNF-alpha (pg/ml) 0 CD4 (%) 29.4 CD8 (%) 15.2 LPS (EU/ml) 5.22708505367464 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190687 SAMN10636581 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.034 host_residential_stratification YoungHealthy treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 39 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 22.3 collection_date 2016-03-15 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 22.3 Weight (kg) 74 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 104 ALT 18 AST 23 Billirubin 28 Cholesterol 5.6 High Density Lipoprotein(HDL) 1.31 Low Density Lipoprotein (LDL) not collected Triglycerides 1.66 Glucose 3.6 Creatinine 81 Ferritin 110 Thyroid Stimulating Hormone (TSH) 2.33 Urea 6.3 Vitamin B12 307 White blood cells 5 HFD_index 0.505025745696762 CRP (mg/L) 2.2 CXCL11 (pg/ml) not collected CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 0 IL-10 (pg/ml) 0 IL-6 (pg/ml) 0 IL-8 (pg/ml) 0 TNF-alpha (pg/ml) 0 CD4 (%) 26.2 CD8 (%) 14.9 LPS (EU/ml) 5.6729975227085 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190688 SAMN10636572 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.031 host_residential_stratification YoungHealthy treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 62 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 29.1 collection_date 2016-08-10 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 29.1 Weight (kg) 82.5 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 70 ALT 19 AST 21 Billirubin 10 Cholesterol 5.9 High Density Lipoprotein(HDL) 1.51 Low Density Lipoprotein (LDL) 3.5 Triglycerides 1.86 Glucose 4.2 Creatinine 54 Ferritin 23 Thyroid Stimulating Hormone (TSH) 2.04 Urea 5.4 Vitamin B12 294 White blood cells 3 HFD_index 0.556333228726097 CRP (mg/L) 1.4 CXCL11 (pg/ml) not collected CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 0 IL-10 (pg/ml) 0 IL-6 (pg/ml) 0 IL-8 (pg/ml) 0 TNF-alpha (pg/ml) 0 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 18.1937799043062 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190689 SAMN10636579 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.033 host_residential_stratification YoungHealthy treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 53 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 41.5 collection_date 2016-05-20 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 41.5 Weight (kg) 113 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 127 ALT 88 AST 72 Billirubin 7 Cholesterol 6.6 High Density Lipoprotein(HDL) 1.44 Low Density Lipoprotein (LDL) 4.2 Triglycerides 2.23 Glucose 12.9 Creatinine 54 Ferritin 142 Thyroid Stimulating Hormone (TSH) 1.1 Urea 5.4 Vitamin B12 279 White blood cells 9.1 HFD_index not collected CRP (mg/L) 14.5 CXCL11 (pg/ml) not collected CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 0 IL-10 (pg/ml) 0 IL-6 (pg/ml) 0 IL-8 (pg/ml) 0 TNF-alpha (pg/ml) 0 CD4 (%) 28.7 CD8 (%) 16.8 LPS (EU/ml) 6.78777869529314 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190690 SAMN10636580 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.033 host_residential_stratification YoungHealthy treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 53 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 42.2 collection_date 2016-08-25 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 42.2 Weight (kg) 115 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 111 ALT 63 AST 48 Billirubin 6 Cholesterol 6.2 High Density Lipoprotein(HDL) 1.5 Low Density Lipoprotein (LDL) 3.9 Triglycerides 1.84 Glucose 8.2 Creatinine 49 Ferritin 93 Thyroid Stimulating Hormone (TSH) 1.48 Urea 4.2 Vitamin B12 212 White blood cells 8.6 HFD_index 0.451204386833909 CRP (mg/L) 10.3 CXCL11 (pg/ml) not collected CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 0 IL-10 (pg/ml) 0 IL-6 (pg/ml) 0 IL-8 (pg/ml) 0 TNF-alpha (pg/ml) 0 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 10.7514450867052 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190691 SAMN10636577 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.032 host_residential_stratification YoungHealthy treatment Placebo time_point week32 host Homo sapiens isolate Stool age not applicable host_age 32 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 30.7 collection_date 2016-10-21 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 30.7 Weight (kg) 95.5 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 83 ALT 48 AST 36 Billirubin 10 Cholesterol 6 High Density Lipoprotein(HDL) 1.22 Low Density Lipoprotein (LDL) 4.2 Triglycerides 1.41 Glucose 8.4 Creatinine 90 Ferritin 49 Thyroid Stimulating Hormone (TSH) 1.09 Urea 5.2 Vitamin B12 301 White blood cells 6.7 HFD_index 0.292952302978568 CRP (mg/L) 0.5 CXCL11 (pg/ml) not collected CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 0 IL-10 (pg/ml) 0 IL-6 (pg/ml) 0 IL-8 (pg/ml) 0 TNF-alpha (pg/ml) 0 CD4 (%) 32.2999999999999 CD8 (%) 26.2 LPS (EU/ml) 6.54004954582989 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190692 SAMN10636295 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.001 host_residential_stratification Community treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 75 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 20.4 collection_date 2015-11-04 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 20.4 Weight (kg) 55 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 87 ALT 23 AST 30 Billirubin 7 Cholesterol 5 High Density Lipoprotein(HDL) 1.79 Low Density Lipoprotein (LDL) 2.9 Triglycerides 0.66 Glucose 5 Creatinine 49 Ferritin 96 Thyroid Stimulating Hormone (TSH) 2.39 Urea 7.3 Vitamin B12 288 White blood cells 6.4 HFD_index 0.507964098466576 CRP (mg/L) not collected CXCL11 (pg/ml) 0 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.754843052019322 IFN-gamma (pg/ml) 3.20218563989539 IL-10 (pg/ml) 0.129001850417737 IL-6 (pg/ml) 0.105639713074219 IL-8 (pg/ml) 12.7503300983164 TNF-alpha (pg/ml) 1.55661854410598 CD4 (%) 30.3 CD8 (%) 44.4 LPS (EU/ml) 9.0539483971853 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190693 SAMN10636296 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.001 host_residential_stratification Community treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 76 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 20.3 collection_date 2016-02-11 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 20.3 Weight (kg) 54.5 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 71 ALT 21 AST 24 Billirubin 9 Cholesterol 5.1 High Density Lipoprotein(HDL) 1.66 Low Density Lipoprotein (LDL) 3.1 Triglycerides 0.59 Glucose 4.3 Creatinine 52 Ferritin 73 Thyroid Stimulating Hormone (TSH) 3.93 Urea 5.7 Vitamin B12 206 White blood cells 6.5 HFD_index 0.507913052560747 CRP (mg/L) 0.5 CXCL11 (pg/ml) 0 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.795176252068603 IFN-gamma (pg/ml) 5.33294019655931 IL-10 (pg/ml) 0.128458278314322 IL-6 (pg/ml) 0.120865548340624 IL-8 (pg/ml) 10.6304772986363 TNF-alpha (pg/ml) 1.33043924485663 CD4 (%) 29.3 CD8 (%) 42 LPS (EU/ml) 20.5931037698459 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190694 SAMN10636550 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.026 host_residential_stratification YoungHealthy treatment Placebo time_point week0 host Homo sapiens isolate Stool age not applicable host_age 26 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 22.1 collection_date 2016-02-03 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 22.1 Weight (kg) 74 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 94 ALT 27 AST 22 Billirubin 8 Cholesterol 4.9 High Density Lipoprotein(HDL) 1.21 Low Density Lipoprotein (LDL) 3.1 Triglycerides 1.3 Glucose 5.1 Creatinine 84 Ferritin 110 Thyroid Stimulating Hormone (TSH) 1.35 Urea 5 Vitamin B12 564 White blood cells 6.9 HFD_index 0.393078698013338 CRP (mg/L) 0.1 CXCL11 (pg/ml) 45.6732533926402 CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 2.97011865949512 IL-10 (pg/ml) 0.106265235465839 IL-6 (pg/ml) 0 IL-8 (pg/ml) 6.47925171583916 TNF-alpha (pg/ml) 0.495639383550609 CD4 (%) 24.8 CD8 (%) 20.7 LPS (EU/ml) 2.1067415730337 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190695 SAMN10636303 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.003 host_residential_stratification Community treatment Placebo time_point week0 host Homo sapiens isolate Stool age not applicable host_age 75 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 26.2 collection_date 2015-11-03 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 26.2 Weight (kg) 67 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 81 ALT 15 AST 28 Billirubin 9 Cholesterol 5.9 High Density Lipoprotein(HDL) 1.46 Low Density Lipoprotein (LDL) 3.9 Triglycerides 1.12 Glucose 5.1 Creatinine 47 Ferritin 164 Thyroid Stimulating Hormone (TSH) 1.32 Urea 5.4 Vitamin B12 401 White blood cells 8.7 HFD_index 0.400537459918379 CRP (mg/L) 1.4 CXCL11 (pg/ml) 206.73785811706 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.731499074471199 IFN-gamma (pg/ml) 1.71145022674801 IL-10 (pg/ml) 0.0558599741955808 IL-6 (pg/ml) 0.132937369665632 IL-8 (pg/ml) 4.58287543685756 TNF-alpha (pg/ml) 1.65118752232941 CD4 (%) 39.1 CD8 (%) 14.8 LPS (EU/ml) 30.8616790618515 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190696 SAMN10636549 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.025 host_residential_stratification YoungHealthy treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 53 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 30.2 collection_date 2016-09-21 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 30.2 Weight (kg) 74.5 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 81 ALT 28 AST 25 Billirubin 10 Cholesterol 5.8 High Density Lipoprotein(HDL) 1.17 Low Density Lipoprotein (LDL) 3.8 Triglycerides 1.76 Glucose 4.5 Creatinine 78 Ferritin 107 Thyroid Stimulating Hormone (TSH) 0.57 Urea 6.5 Vitamin B12 110 White blood cells 3.8 HFD_index 0.480513797854702 CRP (mg/L) 1.7 CXCL11 (pg/ml) 3.36376874495195 CCL11 (pg/ml) 13.2185624323546 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 3.11908132017622 IL-10 (pg/ml) 0.0935934688980158 IL-6 (pg/ml) 0 IL-8 (pg/ml) 9.36203816434317 TNF-alpha (pg/ml) 1.21613809981907 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 7.40163934426229 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190697 SAMN10636348 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.016 host_residential_stratification Community treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 68 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 22.2 collection_date 2016-03-09 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 22.2 Weight (kg) 72.8 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 54 ALT 28 AST 32 Billirubin 15 Cholesterol 4.2 High Density Lipoprotein(HDL) 1.68 Low Density Lipoprotein (LDL) 2 Triglycerides 1.15 Glucose 5 Creatinine 87 Ferritin 126 Thyroid Stimulating Hormone (TSH) 2.81 Urea 5.1 Vitamin B12 562 White blood cells not collected HFD_index not collected CRP (mg/L) 0.6 CXCL11 (pg/ml) 166.416701229996 CCL11 (pg/ml) not collected IL17A (pg/ml) not collected IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) 26.4 CD8 (%) 9.31 LPS (EU/ml) 11.590909090909 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190698 SAMN10636559 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.028 host_residential_stratification YoungHealthy treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 52 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 24.3 collection_date 2016-05-10 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.3 Weight (kg) 57 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 119 ALT 31 AST 26 Billirubin 16 Cholesterol 5.2 High Density Lipoprotein(HDL) 1.81 Low Density Lipoprotein (LDL) 2.8 Triglycerides 1.28 Glucose 5.1 Creatinine 66 Ferritin 143 Thyroid Stimulating Hormone (TSH) 2.17 Urea 6.8 Vitamin B12 174 White blood cells 7.1 HFD_index 0.583617457539201 CRP (mg/L) 1 CXCL11 (pg/ml) 0.999608508389733 CCL11 (pg/ml) 0 IL17A (pg/ml) 1.81193638201314e-05 IFN-gamma (pg/ml) 5.29069342842782 IL-10 (pg/ml) 0.0888387875813251 IL-6 (pg/ml) 0.10339904807479 IL-8 (pg/ml) 8.2236082140125 TNF-alpha (pg/ml) 2.11607151166405 CD4 (%) 17.3 CD8 (%) 11.3 LPS (EU/ml) 19.6291866028708 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190699 SAMN10636552 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.026 host_residential_stratification YoungHealthy treatment Placebo time_point week26 host Homo sapiens isolate Stool age not applicable host_age 27 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 22.4 collection_date 2016-08-03 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 22.4 Weight (kg) 74.5 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 83 ALT 22 AST 25 Billirubin 13 Cholesterol 4.4 High Density Lipoprotein(HDL) 1.18 Low Density Lipoprotein (LDL) 2.9 Triglycerides 0.63 Glucose 4.9 Creatinine 77 Ferritin 92 Thyroid Stimulating Hormone (TSH) 0.83 Urea 3.8 Vitamin B12 488 White blood cells 6.3 HFD_index 0.369241917558779 CRP (mg/L) 0.1 CXCL11 (pg/ml) not applicable CCL11 (pg/ml) 9.15312660609719 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 1.92701677490635 IL-10 (pg/ml) 0.293303218224786 IL-6 (pg/ml) 0.0443579995884286 IL-8 (pg/ml) 5.70064587373294 TNF-alpha (pg/ml) 1.69110739398567 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 3.70491803278688 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190700 SAMN10636349 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.016 host_residential_stratification Community treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 69 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 21.9 collection_date 2016-06-08 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 21.9 Weight (kg) 71.9 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 47 ALT 25 AST 30 Billirubin 18 Cholesterol 3.8 High Density Lipoprotein(HDL) 1.64 Low Density Lipoprotein (LDL) 1.7 Triglycerides 0.99 Glucose 6.4 Creatinine 81 Ferritin 114 Thyroid Stimulating Hormone (TSH) 2.01 Urea 6.3 Vitamin B12 476 White blood cells 5.6 HFD_index 0.526570550106034 CRP (mg/L) 0.6 CXCL11 (pg/ml) 20.3064473790021 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.768985406038357 IFN-gamma (pg/ml) 3.73413316837257 IL-10 (pg/ml) 0.112767280369578 IL-6 (pg/ml) 0.298240402713305 IL-8 (pg/ml) 7.43444201197164 TNF-alpha (pg/ml) 1.49322670142544 CD4 (%) 40.2999999999999 CD8 (%) 7.48 LPS (EU/ml) 12.188995215311 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190701 SAMN10636551 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.026 host_residential_stratification YoungHealthy treatment Placebo time_point week13 host Homo sapiens isolate Stool age not applicable host_age 27 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 22.4 collection_date 2016-05-05 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 22.4 Weight (kg) 75 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 102 ALT 21 AST 19 Billirubin 8 Cholesterol 4.5 High Density Lipoprotein(HDL) 1.27 Low Density Lipoprotein (LDL) 2.6 Triglycerides 1.41 Glucose 4.4 Creatinine 83 Ferritin 87 Thyroid Stimulating Hormone (TSH) 1.55 Urea 4.7 Vitamin B12 491 White blood cells 7 HFD_index 0.393376944905838 CRP (mg/L) 0.2 CXCL11 (pg/ml) not applicable CCL11 (pg/ml) 5.65156080904568 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 1.46448616280727 IL-10 (pg/ml) 0.0954993818189919 IL-6 (pg/ml) 0.0101485902496575 IL-8 (pg/ml) 5.26053229068426 TNF-alpha (pg/ml) 1.70286096699133 CD4 (%) 32.7 CD8 (%) 26 LPS (EU/ml) 8.38524590163934 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190702 SAMN10636535 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.021 host_residential_stratification YoungHealthy treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 64 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 23.4 collection_date 2016-01-26 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23.4 Weight (kg) 78.5 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 72 ALT 27 AST 31 Billirubin 24 Cholesterol 5.9 High Density Lipoprotein(HDL) 1.52 Low Density Lipoprotein (LDL) 3.8 Triglycerides 1.21 Glucose 4.6 Creatinine 83 Ferritin 52 Thyroid Stimulating Hormone (TSH) 1.02 Urea 4.3 Vitamin B12 718 White blood cells 7.8 HFD_index 0.408878137620472 CRP (mg/L) 0.6 CXCL11 (pg/ml) 16.1639288432702 CCL11 (pg/ml) 1.96989278830714 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 2.33766741211322 IL-10 (pg/ml) 0.0988401143639779 IL-6 (pg/ml) 0.501694788578995 IL-8 (pg/ml) 8.77510715683824 TNF-alpha (pg/ml) 1.84448362874901 CD4 (%) 30.5 CD8 (%) 34.1 LPS (EU/ml) 5.80327868852459 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190703 SAMN10636538 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.021 host_residential_stratification YoungHealthy treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 64 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 22.8 collection_date 2016-09-02 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 22.8 Weight (kg) 76.5 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 68 ALT 20 AST 27 Billirubin 31 Cholesterol 5.6 High Density Lipoprotein(HDL) 1.52 Low Density Lipoprotein (LDL) 3.7 Triglycerides 0.96 Glucose 4.9 Creatinine 91 Ferritin 68 Thyroid Stimulating Hormone (TSH) 0.73 Urea 5 Vitamin B12 683 White blood cells 8.1 HFD_index 0.408878137620472 CRP (mg/L) 0.8 CXCL11 (pg/ml) 11.9218710054155 CCL11 (pg/ml) 6.02805962759863 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 1.69083215932963 IL-10 (pg/ml) 0.0676394937444304 IL-6 (pg/ml) 0.419458605945832 IL-8 (pg/ml) 9.78191316078729 TNF-alpha (pg/ml) 1.82080698936562 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 7.52459016393442 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190704 SAMN10636510 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.010 host_residential_stratification YoungHealthy treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 31 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 22.8 collection_date 2016-01-29 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 22.8 Weight (kg) 72.3 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 86 ALT 20 AST 22 Billirubin 16 Cholesterol 6.6 High Density Lipoprotein(HDL) 1.57 Low Density Lipoprotein (LDL) 4.6 Triglycerides 0.85 Glucose 5.1 Creatinine 73 Ferritin 173 Thyroid Stimulating Hormone (TSH) 2.95 Urea 6.8 Vitamin B12 245 White blood cells 6 HFD_index 0.469424709663705 CRP (mg/L) not collected CXCL11 (pg/ml) not applicable CCL11 (pg/ml) 2.05056248092407 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 7.11392937491427 IL-10 (pg/ml) 0.084572357442002 IL-6 (pg/ml) 0 IL-8 (pg/ml) 4.24024040923773 TNF-alpha (pg/ml) 1.2074850148105 CD4 (%) 36.4 CD8 (%) 20.8 LPS (EU/ml) 7.88524590163934 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190705 SAMN10636519 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.015 host_residential_stratification YoungHealthy treatment Placebo time_point week0 host Homo sapiens isolate Stool age not applicable host_age 24 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 23.5 collection_date 2015-11-17 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23.5 Weight (kg) 83 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 76 ALT 17 AST 24 Billirubin 12 Cholesterol 4.1 High Density Lipoprotein(HDL) 1.21 Low Density Lipoprotein (LDL) 2.4 Triglycerides 1.09 Glucose 4.4 Creatinine 96 Ferritin 112 Thyroid Stimulating Hormone (TSH) 1.47 Urea 5.6 Vitamin B12 242 White blood cells 5.4 HFD_index 0.473449575639199 CRP (mg/L) 1 CXCL11 (pg/ml) 69.8282161131453 CCL11 (pg/ml) 3.10365015194309 IL17A (pg/ml) 1.02389171330119e-06 IFN-gamma (pg/ml) 1.93132230290651 IL-10 (pg/ml) 0.0969302936485157 IL-6 (pg/ml) 0 IL-8 (pg/ml) 4.78913927653984 TNF-alpha (pg/ml) 0.748956825225776 CD4 (%) 40.7999999999999 CD8 (%) 18 LPS (EU/ml) 12.6885245901639 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190706 SAMN10636509 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.010 host_residential_stratification YoungHealthy treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 31 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 22.1 collection_date 2015-10-29 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 22.1 Weight (kg) 70 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 87 ALT 25 AST 25 Billirubin 14 Cholesterol 5.3 High Density Lipoprotein(HDL) 1.57 Low Density Lipoprotein (LDL) 3.1 Triglycerides 1.27 Glucose 5 Creatinine 67 Ferritin 167 Thyroid Stimulating Hormone (TSH) 1.72 Urea 7 Vitamin B12 307 White blood cells 6.1 HFD_index 0.457057647196975 CRP (mg/L) 0.1 CXCL11 (pg/ml) not applicable CCL11 (pg/ml) 3.24317862826014 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 11.4484063244324 IL-10 (pg/ml) 0.0950226913296258 IL-6 (pg/ml) 0 IL-8 (pg/ml) 5.02659213054996 TNF-alpha (pg/ml) 0.962051880725428 CD4 (%) 41.8 CD8 (%) 21.3 LPS (EU/ml) 9.64754098360655 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190707 SAMN10636512 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.010 host_residential_stratification YoungHealthy treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 31 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 22.1 collection_date 2016-06-10 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 22.1 Weight (kg) 70.8 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 87 ALT 34 AST 40 Billirubin 14 Cholesterol 5.6 High Density Lipoprotein(HDL) 1.56 Low Density Lipoprotein (LDL) 3.4 Triglycerides 1.28 Glucose 4.9 Creatinine 75 Ferritin 135 Thyroid Stimulating Hormone (TSH) 1.99 Urea 7.1 Vitamin B12 243 White blood cells 5.2 HFD_index 0.514058430648339 CRP (mg/L) 2.1 CXCL11 (pg/ml) not applicable CCL11 (pg/ml) 22.5875983621747 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 6.01012532620246 IL-10 (pg/ml) 0.0988401143639779 IL-6 (pg/ml) 0.023793451574286 IL-8 (pg/ml) 5.66630121483694 TNF-alpha (pg/ml) 1.05909736036339 CD4 (%) 39.2999999999999 CD8 (%) 9.94 LPS (EU/ml) 9.24590163934426 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190708 SAMN10636491 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.003 host_residential_stratification YoungHealthy treatment Placebo time_point week13 host Homo sapiens isolate Stool age not applicable host_age 31 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 26.2 collection_date 2016-01-13 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 26.2 Weight (kg) 74 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 127 ALT 26 AST 30 Billirubin 6 Cholesterol 4.8 High Density Lipoprotein(HDL) 1.17 Low Density Lipoprotein (LDL) 3.3 Triglycerides 0.71 Glucose 4.8 Creatinine 70 Ferritin 14 Thyroid Stimulating Hormone (TSH) 1.2 Urea 6.9 Vitamin B12 449 White blood cells 6.5 HFD_index 0.397558008926186 CRP (mg/L) 1.5 CXCL11 (pg/ml) 4363.00634690259 CCL11 (pg/ml) 4.93557483648223 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 4.15694712728033 IL-10 (pg/ml) 0.084572357442002 IL-6 (pg/ml) 0.199890011578735 IL-8 (pg/ml) 13.9049777595024 TNF-alpha (pg/ml) 0.470301255695078 CD4 (%) 33.7 CD8 (%) 29.4 LPS (EU/ml) 20.7504721050054 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190709 SAMN10636492 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.003 host_residential_stratification YoungHealthy treatment Placebo time_point week26 host Homo sapiens isolate Stool age not applicable host_age 31 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 24.8 collection_date 2016-04-13 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.8 Weight (kg) 70 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 130 ALT 29 AST 44 Billirubin 12 Cholesterol 4.1 High Density Lipoprotein(HDL) 1.13 Low Density Lipoprotein (LDL) 2.4 Triglycerides 1.35 Glucose 4.9 Creatinine 76 Ferritin 26 Thyroid Stimulating Hormone (TSH) 0.81 Urea 4.8 Vitamin B12 415 White blood cells 5.3 HFD_index 0.437467554126793 CRP (mg/L) 1.3 CXCL11 (pg/ml) 1853.80927541305 CCL11 (pg/ml) 6.33079173178744 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 4.01050098513587 IL-10 (pg/ml) 0.0935934688980158 IL-6 (pg/ml) 0.0560171203360812 IL-8 (pg/ml) 6.75075430751997 TNF-alpha (pg/ml) 0.841418490789875 CD4 (%) 22.2 CD8 (%) 28.1 LPS (EU/ml) 20.8122537476977 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190710 SAMN10636490 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.003 host_residential_stratification YoungHealthy treatment Placebo time_point week0 host Homo sapiens isolate Stool age not applicable host_age 30 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 25.5 collection_date 2015-10-15 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 25.5 Weight (kg) 72 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 146 ALT 29 AST 42 Billirubin 8 Cholesterol 5.5 High Density Lipoprotein(HDL) 1.32 Low Density Lipoprotein (LDL) 3.2 Triglycerides 2.18 Glucose 4.3 Creatinine 75 Ferritin 13 Thyroid Stimulating Hormone (TSH) 1.24 Urea 6 Vitamin B12 383 White blood cells 7.8 HFD_index 0.402707851607255 CRP (mg/L) 1.8 CXCL11 (pg/ml) 2144.1345924603 CCL11 (pg/ml) 5.04468046604544 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 3.38290145863454 IL-10 (pg/ml) 0.0671724319136254 IL-6 (pg/ml) 0.187060752357819 IL-8 (pg/ml) 10.2296008887274 TNF-alpha (pg/ml) 0.43567111323237 CD4 (%) 37.5 CD8 (%) 30.7 LPS (EU/ml) 6.75197584687478 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190711 SAMN10636489 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.002 host_residential_stratification YoungHealthy treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 32 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 26.5 collection_date 2016-05-16 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 26.5 Weight (kg) 86 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 75 ALT 50 AST 33 Billirubin 13 Cholesterol 6.7 High Density Lipoprotein(HDL) 1.18 Low Density Lipoprotein (LDL) 4.5 Triglycerides 2.26 Glucose 4.6 Creatinine 77 Ferritin 106 Thyroid Stimulating Hormone (TSH) 2.6 Urea 5.5 Vitamin B12 261 White blood cells 5.6 HFD_index 0.469691584871282 CRP (mg/L) 1.7 CXCL11 (pg/ml) 13.8212375485365 CCL11 (pg/ml) 3.02165101567995 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 3.71826434753617 IL-10 (pg/ml) 0.200547010822886 IL-6 (pg/ml) 0.134344164754492 IL-8 (pg/ml) 6.36480349843535 TNF-alpha (pg/ml) 0.411581014744662 CD4 (%) 40.4 CD8 (%) 25.6 LPS (EU/ml) 20.8553843284452 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190712 SAMN10636487 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.002 host_residential_stratification YoungHealthy treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 32 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 26 collection_date 2016-01-08 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 26 Weight (kg) 87 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 75 ALT 56 AST 29 Billirubin 16 Cholesterol 7.3 High Density Lipoprotein(HDL) 1.17 Low Density Lipoprotein (LDL) 5.5 Triglycerides 1.34 Glucose 4.6 Creatinine 91 Ferritin 105 Thyroid Stimulating Hormone (TSH) 2.95 Urea 4.4 Vitamin B12 242 White blood cells 5.9 HFD_index 0.411444163827266 CRP (mg/L) 2 CXCL11 (pg/ml) 43.1456128925742 CCL11 (pg/ml) 3.26607377804054 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 6.0326663857257 IL-10 (pg/ml) 0.0964531835898668 IL-6 (pg/ml) 0.23771558482683 IL-8 (pg/ml) 5.74480770319348 TNF-alpha (pg/ml) 0.501674020530153 CD4 (%) 35.7999999999999 CD8 (%) 20 LPS (EU/ml) 31.2 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190713 SAMN10636488 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.002 host_residential_stratification YoungHealthy treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 32 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 25.9 collection_date 2016-03-16 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 25.9 Weight (kg) 84 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 72 ALT 34 AST 25 Billirubin 32 Cholesterol 5.9 High Density Lipoprotein(HDL) 1.14 Low Density Lipoprotein (LDL) 4.2 Triglycerides 1.29 Glucose 4.9 Creatinine 86 Ferritin 125 Thyroid Stimulating Hormone (TSH) 2.02 Urea 5.6 Vitamin B12 239 White blood cells 6.1 HFD_index 0.456453797401262 CRP (mg/L) 1.4 CXCL11 (pg/ml) 19.6136139079685 CCL11 (pg/ml) 5.95365921019824 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 2.60292742604762 IL-10 (pg/ml) 0.118535449658329 IL-6 (pg/ml) 0.225209173048876 IL-8 (pg/ml) 4.50173268087856 TNF-alpha (pg/ml) 0.432221877314142 CD4 (%) 33.7999999999999 CD8 (%) 21.6 LPS (EU/ml) 20.928822884853 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190714 SAMN10636485 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.001 host_residential_stratification YoungHealthy treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 27 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 19.9 collection_date 2016-05-15 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 19.9 Weight (kg) 66 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 58 ALT 17 AST 23 Billirubin 17 Cholesterol 6.3 High Density Lipoprotein(HDL) 1.37 Low Density Lipoprotein (LDL) 4.2 Triglycerides 1.54 Glucose 5.3 Creatinine 79 Ferritin 37 Thyroid Stimulating Hormone (TSH) 1.64 Urea 6 Vitamin B12 150 White blood cells 5 HFD_index 0.48714104621224 CRP (mg/L) 0.1 CXCL11 (pg/ml) 3.36376874495195 CCL11 (pg/ml) 2.20846898095676 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 6.93700202547761 IL-10 (pg/ml) 0.142816788349063 IL-6 (pg/ml) 0.161010761264412 IL-8 (pg/ml) 7.50266452219919 TNF-alpha (pg/ml) 0.446034073109696 CD4 (%) 29.5 CD8 (%) 26.1 LPS (EU/ml) 6.71747138227682 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190715 SAMN10636486 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.002 host_residential_stratification YoungHealthy treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 31 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 25.4 collection_date 2015-10-08 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 25.4 Weight (kg) 85 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 79 ALT 44 AST 28 Billirubin 14 Cholesterol 5.6 High Density Lipoprotein(HDL) 1.11 Low Density Lipoprotein (LDL) 3.9 Triglycerides 1.34 Glucose 4.9 Creatinine 90 Ferritin 99 Thyroid Stimulating Hormone (TSH) 1.42 Urea 5.4 Vitamin B12 237 White blood cells 5.1 HFD_index 0.451127012596059 CRP (mg/L) 2.5 CXCL11 (pg/ml) 10.0305548761175 CCL11 (pg/ml) 2.05056248092407 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 4.3970344070602 IL-10 (pg/ml) 0.118535449658329 IL-6 (pg/ml) 0.331876695390108 IL-8 (pg/ml) 8.23224061622775 TNF-alpha (pg/ml) 0.589761158723482 CD4 (%) 37.7999999999999 CD8 (%) 20.9 LPS (EU/ml) 10.3 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190716 SAMN10636578 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.033 host_residential_stratification YoungHealthy treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 53 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 41.4 collection_date 2016-02-25 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 41.4 Weight (kg) 112 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 116 ALT 52 AST 34 Billirubin 5 Cholesterol 6.3 High Density Lipoprotein(HDL) 1.39 Low Density Lipoprotein (LDL) 4 Triglycerides 1.93 Glucose 4.8 Creatinine 54 Ferritin 65 Thyroid Stimulating Hormone (TSH) 1.11 Urea 5.1 Vitamin B12 249 White blood cells 9.4 HFD_index not collected CRP (mg/L) 20.9 CXCL11 (pg/ml) not collected CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 0 IL-10 (pg/ml) 0 IL-6 (pg/ml) 0 IL-8 (pg/ml) 0 TNF-alpha (pg/ml) 0 CD4 (%) 25 CD8 (%) 19.1 LPS (EU/ml) 7.03550784475639 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190717 SAMN10636575 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.032 host_residential_stratification YoungHealthy treatment Placebo time_point week13 host Homo sapiens isolate Stool age not applicable host_age 31 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 30.7 collection_date 2016-07-01 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 30.7 Weight (kg) 94 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 83 ALT 40 AST 34 Billirubin 15 Cholesterol 6.2 High Density Lipoprotein(HDL) 1.2 Low Density Lipoprotein (LDL) 4.6 Triglycerides 0.89 Glucose 5.1 Creatinine 85 Ferritin 45 Thyroid Stimulating Hormone (TSH) 1.22 Urea 4.8 Vitamin B12 258 White blood cells 6.5 HFD_index 0.327326474175181 CRP (mg/L) 2.29999999999999 CXCL11 (pg/ml) not collected CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 0 IL-10 (pg/ml) 0 IL-6 (pg/ml) 0 IL-8 (pg/ml) 0 TNF-alpha (pg/ml) 0 CD4 (%) 22.2 CD8 (%) 36.6 LPS (EU/ml) 19.0011961722488 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190718 SAMN10636571 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.031 host_residential_stratification YoungHealthy treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 61 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 28.4 collection_date 2016-05-12 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 28.4 Weight (kg) 80 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 69 ALT 20 AST 20 Billirubin 10 Cholesterol 5.9 High Density Lipoprotein(HDL) 1.69 Low Density Lipoprotein (LDL) 3.5 Triglycerides 1.44 Glucose 4.5 Creatinine 60 Ferritin 31 Thyroid Stimulating Hormone (TSH) 2.53 Urea 5.3 Vitamin B12 328 White blood cells 3.3 HFD_index 0.509807473831683 CRP (mg/L) not collected CXCL11 (pg/ml) not collected CCL11 (pg/ml) 0 IL17A (pg/ml) 4.0039914192866e-05 IFN-gamma (pg/ml) 2.4332019419062 IL-10 (pg/ml) 0.177218926691943 IL-6 (pg/ml) 0 IL-8 (pg/ml) 18.1434393046319 TNF-alpha (pg/ml) 1.96328747166896 CD4 (%) 42.3 CD8 (%) 13.1 LPS (EU/ml) 18.6423444976076 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190719 SAMN10636570 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.031 host_residential_stratification YoungHealthy treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 61 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 28 collection_date 2016-02-24 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 28 Weight (kg) 79 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 67 ALT 20 AST 20 Billirubin 10 Cholesterol 6 High Density Lipoprotein(HDL) 1.86 Low Density Lipoprotein (LDL) 3.7 Triglycerides 0.95 Glucose 3.8 Creatinine 60 Ferritin 35 Thyroid Stimulating Hormone (TSH) 2.63 Urea 6 Vitamin B12 287 White blood cells 4.7 HFD_index 0.516984998299148 CRP (mg/L) 1.8 CXCL11 (pg/ml) not collected CCL11 (pg/ml) 0 IL17A (pg/ml) 1.87083991094984e-06 IFN-gamma (pg/ml) 1.8538826827327 IL-10 (pg/ml) 0.184149752735049 IL-6 (pg/ml) 0.27774940500916 IL-8 (pg/ml) 18.0798212807479 TNF-alpha (pg/ml) 2.24709188314907 CD4 (%) 46.9 CD8 (%) 13.6 LPS (EU/ml) 11.8002392344497 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190720 SAMN10636391 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.027 host_residential_stratification Community treatment Placebo time_point week13 host Homo sapiens isolate Stool age not applicable host_age 83 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 23.5 collection_date 2016-08-10 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23.5 Weight (kg) 53.5 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 125 Alkaline Phosphatase 66 ALT 23 AST 33 Billirubin 10 Cholesterol 4.3 High Density Lipoprotein(HDL) 1.5 Low Density Lipoprotein (LDL) 2.3 Triglycerides 1 Glucose 5 Creatinine 66 Ferritin 99 Thyroid Stimulating Hormone (TSH) 1.71 Urea 5.3 Vitamin B12 214 White blood cells 5.6 HFD_index 0.430247696525615 CRP (mg/L) 1.2 CXCL11 (pg/ml) not collected CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 4.20761654459344 IL-10 (pg/ml) 0.151420313424907 IL-6 (pg/ml) 1.02470364349854 IL-8 (pg/ml) 13.5899657059387 TNF-alpha (pg/ml) 1.40435738511573 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 4.92981007431874 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190721 SAMN10636379 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.024 host_residential_stratification Community treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 69 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 27.3 collection_date 2016-07-19 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 27.3 Weight (kg) 70 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 63 ALT 13 AST 26 Billirubin 12 Cholesterol 4.6 High Density Lipoprotein(HDL) 1.47 Low Density Lipoprotein (LDL) 2.8 Triglycerides 0.61 Glucose 6.6 Creatinine 64 Ferritin 195 Thyroid Stimulating Hormone (TSH) 2.06 Urea 7.2 Vitamin B12 239 White blood cells 4.6 HFD_index 0.356438602814326 CRP (mg/L) 7 CXCL11 (pg/ml) 666.650897300344 CCL11 (pg/ml) 0 IL17A (pg/ml) 1.34572033909257 IFN-gamma (pg/ml) 6.55170984893546 IL-10 (pg/ml) 0.190784645841804 IL-6 (pg/ml) 0.715921837471016 IL-8 (pg/ml) 15.005466732442 TNF-alpha (pg/ml) 1.30627660301192 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 7.77869529314615 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190722 SAMN10636375 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.023 host_residential_stratification Community treatment Placebo time_point week13 host Homo sapiens isolate Stool age not applicable host_age 85 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 28 collection_date 2016-07-19 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 28 Weight (kg) 82 Appendix A - Charlson co-morbidity 1 Appendix B - Barthel Score 20 Appendix C - FIM 124 Alkaline Phosphatase 73 ALT 24 AST 27 Billirubin 9 Cholesterol 4.3 High Density Lipoprotein(HDL) 1.27 Low Density Lipoprotein (LDL) 1.8 Triglycerides 2.6 Glucose 5.6 Creatinine 113 Ferritin 17 Thyroid Stimulating Hormone (TSH) 1.52 Urea 5.9 Vitamin B12 199 White blood cells 7.3 HFD_index 0.469051579399755 CRP (mg/L) 1.6 CXCL11 (pg/ml) 33.5842935962254 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.878258577960249 IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190723 SAMN10636569 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.030 host_residential_stratification YoungHealthy treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 32 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 21.2 collection_date 2016-10-06 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 21.2 Weight (kg) 74 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 96 ALT 40 AST 32 Billirubin 27 Cholesterol 5.2 High Density Lipoprotein(HDL) 1.44 Low Density Lipoprotein (LDL) 3.4 Triglycerides 0.86 Glucose 4.9 Creatinine 75 Ferritin 179 Thyroid Stimulating Hormone (TSH) 1.11 Urea 4.1 Vitamin B12 150 White blood cells 7.7 HFD_index 0.323154506888657 CRP (mg/L) 0.5 CXCL11 (pg/ml) 11.0111344680731 CCL11 (pg/ml) 0 IL17A (pg/ml) 4.34427094574775e-06 IFN-gamma (pg/ml) 1.38792282748333 IL-10 (pg/ml) 0.24313712876259 IL-6 (pg/ml) 0.0280617325273718 IL-8 (pg/ml) 4.91396484073456 TNF-alpha (pg/ml) 1.70678051205282 CD4 (%) 22.1 CD8 (%) 26.8 LPS (EU/ml) 11.7404306220095 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190724 SAMN10636507 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.008 host_residential_stratification YoungHealthy treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 28 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 19.4 collection_date 2016-04-20 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 19.4 Weight (kg) 56 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 53 ALT 16 AST 25 Billirubin 8 Cholesterol 6.8 High Density Lipoprotein(HDL) 2.61 Low Density Lipoprotein (LDL) 3.7 Triglycerides 1 Glucose 4.3 Creatinine 87 Ferritin 9 Thyroid Stimulating Hormone (TSH) 2.11 Urea 5 Vitamin B12 130 White blood cells 4.9 HFD_index 0.581764477912797 CRP (mg/L) 0.8 CXCL11 (pg/ml) not collected CCL11 (pg/ml) not collected IL17A (pg/ml) not collected IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) 28 CD8 (%) 13.2 LPS (EU/ml) 5.79508196721311 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190725 SAMN10636503 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.007 host_residential_stratification YoungHealthy treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 40 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 19.5 collection_date 2016-04-20 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 19.5 Weight (kg) 53 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 49 ALT 8 AST not collected Billirubin 10 Cholesterol 5.1 High Density Lipoprotein(HDL) 1.69 Low Density Lipoprotein (LDL) 3 Triglycerides 0.79 Glucose 3.6 Creatinine 49 Ferritin 33 Thyroid Stimulating Hormone (TSH) 1.49 Urea 4.6 Vitamin B12 406 White blood cells 11.7 HFD_index 0.582118789965887 CRP (mg/L) 2.29999999999999 CXCL11 (pg/ml) 6.87106436254952 CCL11 (pg/ml) 3.84851372704216 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 3.2860673286662 IL-10 (pg/ml) 0.191592786380264 IL-6 (pg/ml) 0.144425212645468 IL-8 (pg/ml) 5.95832537167603 TNF-alpha (pg/ml) 0.554367413487144 CD4 (%) 51.5 CD8 (%) 13.8 LPS (EU/ml) 8.38524590163934 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190726 SAMN10636504 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.007 host_residential_stratification YoungHealthy treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 40 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 19.2 collection_date 2016-05-30 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 19.2 Weight (kg) 53 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 53 ALT 12 AST 22 Billirubin 8 Cholesterol 7.1 High Density Lipoprotein(HDL) 2.31 Low Density Lipoprotein (LDL) not collected Triglycerides 1.29 Glucose 3.7 Creatinine 46 Ferritin 26 Thyroid Stimulating Hormone (TSH) 1.8 Urea 3.8 Vitamin B12 412 White blood cells 12.3 HFD_index 0.637933260038874 CRP (mg/L) 2.4 CXCL11 (pg/ml) 5.11712980085734 CCL11 (pg/ml) 23.6872962967235 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 4.8162189903402 IL-10 (pg/ml) 0.216023280150538 IL-6 (pg/ml) 0.0856409162169285 IL-8 (pg/ml) 4.62767056672923 TNF-alpha (pg/ml) 0.515677232311947 CD4 (%) 58 CD8 (%) 14.1 LPS (EU/ml) 9.49180327868852 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190727 SAMN10636300 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.002 host_residential_stratification Community treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 75 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 33.5 collection_date 2016-02-01 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 33.5 Weight (kg) 113.5 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 125 Alkaline Phosphatase 57 ALT 40 AST 32 Billirubin 25 Cholesterol 4 High Density Lipoprotein(HDL) 1.39 Low Density Lipoprotein (LDL) not collected Triglycerides 2.03 Glucose 5.2 Creatinine 106 Ferritin 88 Thyroid Stimulating Hormone (TSH) 4.62 Urea 4.8 Vitamin B12 139 White blood cells 5.8 HFD_index not collected CRP (mg/L) 0.6 CXCL11 (pg/ml) 34.5454303254764 CCL11 (pg/ml) 107.770062793224 IL17A (pg/ml) 0.804784239145902 IFN-gamma (pg/ml) 3.00418160517766 IL-10 (pg/ml) 0.265446775983028 IL-6 (pg/ml) 0.437084575469763 IL-8 (pg/ml) 17.5083351377253 TNF-alpha (pg/ml) 2.39155976181476 CD4 (%) 35.2 CD8 (%) 9.03999999999999 LPS (EU/ml) 30.7707551348704 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190728 SAMN10636422 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.005 host_residential_stratification LongStay treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 97 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 4 host_body_mass_index 22.1 collection_date 2015-04-21 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 22.1 Weight (kg) 55.1 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 4 Appendix C - FIM 48 Alkaline Phosphatase 87 ALT 7 AST 15 Billirubin 5 Cholesterol 4.7 High Density Lipoprotein(HDL) 0.92 Low Density Lipoprotein (LDL) 2.5 Triglycerides 2.9 Glucose 6.5 Creatinine 107 Ferritin 8 Thyroid Stimulating Hormone (TSH) 1.09 Urea 11.1 Vitamin B12 257 White blood cells 7.7 HFD_index 0.262460167443155 CRP (mg/L) 11.2 CXCL11 (pg/ml) 656.712284667062 CCL11 (pg/ml) 319.600796815169 IL17A (pg/ml) 2.80152620754105 IFN-gamma (pg/ml) 7.05239145283927 IL-10 (pg/ml) 0.380235668648759 IL-6 (pg/ml) 1.95005622760163 IL-8 (pg/ml) 18.3566885682357 TNF-alpha (pg/ml) 4.12229205530362 CD4 (%) 34 CD8 (%) 23.5 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190729 SAMN10636421 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.005 host_residential_stratification LongStay treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 97 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 6 host_body_mass_index 23 collection_date 2014-12-16 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23 Weight (kg) 57.2 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 6 Appendix C - FIM 47 Alkaline Phosphatase 84 ALT 12 AST 20 Billirubin 5 Cholesterol 4.1 High Density Lipoprotein(HDL) 0.82 Low Density Lipoprotein (LDL) 1.6 Triglycerides 3.64 Glucose 6.1 Creatinine 112 Ferritin 13 Thyroid Stimulating Hormone (TSH) 1.06 Urea 12.2 Vitamin B12 263 White blood cells 8.5 HFD_index not collected CRP (mg/L) 59.6 CXCL11 (pg/ml) 762.612200521752 CCL11 (pg/ml) 265.902365884633 IL17A (pg/ml) 2.6920272011322 IFN-gamma (pg/ml) 7.61605268061955 IL-10 (pg/ml) 0.714643820214588 IL-6 (pg/ml) 4.14836371320181 IL-8 (pg/ml) 14.5858071469753 TNF-alpha (pg/ml) 4.5943000074968 CD4 (%) 30.3 CD8 (%) 7.22 LPS (EU/ml) 6.72283356258597 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190730 SAMN10636420 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.004 host_residential_stratification LongStay treatment Placebo time_point week32 host Homo sapiens isolate Stool age not applicable host_age 80 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 3 host_body_mass_index 43 collection_date 2015-09-02 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 43 Weight (kg) 110.4 Appendix A - Charlson co-morbidity 10 Appendix B - Barthel Score 3 Appendix C - FIM 23 Alkaline Phosphatase 106 ALT 11 AST 17 Billirubin 6 Cholesterol 7.7 High Density Lipoprotein(HDL) 1.11 Low Density Lipoprotein (LDL) not collected Triglycerides 4.55 Glucose 6 Creatinine 179 Ferritin 41 Thyroid Stimulating Hormone (TSH) 1.53 Urea 18.9 Vitamin B12 250 White blood cells 8 HFD_index 0.398152531918132 CRP (mg/L) 17.8999999999999 CXCL11 (pg/ml) 877.656900636593 CCL11 (pg/ml) 876.52961534017 IL17A (pg/ml) 7.01120413159422 IFN-gamma (pg/ml) 6.55802897883297 IL-10 (pg/ml) 0.462824001061783 IL-6 (pg/ml) 2.21603823722431 IL-8 (pg/ml) 11.8952926481763 TNF-alpha (pg/ml) 4.28975025587716 CD4 (%) 44.5 CD8 (%) 27.8 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190731 SAMN10636419 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.004 host_residential_stratification LongStay treatment Placebo time_point week26 host Homo sapiens isolate Stool age not applicable host_age 80 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 3 host_body_mass_index 40 collection_date 2015-07-21 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 40 Weight (kg) 110.8 Appendix A - Charlson co-morbidity 10 Appendix B - Barthel Score 3 Appendix C - FIM 23 Alkaline Phosphatase 110 ALT 9 AST 17 Billirubin 4 Cholesterol 7.2 High Density Lipoprotein(HDL) 1.03 Low Density Lipoprotein (LDL) 4.5 Triglycerides 3.63 Glucose 4.5 Creatinine 177 Ferritin 40 Thyroid Stimulating Hormone (TSH) 1.84 Urea 19 Vitamin B12 242 White blood cells 6.8 HFD_index 0.299978815171327 CRP (mg/L) 13.4 CXCL11 (pg/ml) 1909.19663424198 CCL11 (pg/ml) not applicable IL17A (pg/ml) 5.7671762613316 IFN-gamma (pg/ml) 12.2064065072628 IL-10 (pg/ml) 0.317076759328431 IL-6 (pg/ml) 3.03503100582975 IL-8 (pg/ml) 19.6519037885713 TNF-alpha (pg/ml) 8.19940514338209 CD4 (%) 43.2 CD8 (%) 28.1 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190732 SAMN10636418 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.004 host_residential_stratification LongStay treatment Placebo time_point week13 host Homo sapiens isolate Stool age not applicable host_age 79 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 4 host_body_mass_index 44 collection_date 2015-04-23 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 44 Weight (kg) 113.4 Appendix A - Charlson co-morbidity 8 Appendix B - Barthel Score 4 Appendix C - FIM 46 Alkaline Phosphatase 106 ALT 9 AST 18 Billirubin 7 Cholesterol 6.8 High Density Lipoprotein(HDL) 0.97 Low Density Lipoprotein (LDL) 4.3 Triglycerides 3.24 Glucose 6.2 Creatinine 168 Ferritin 39 Thyroid Stimulating Hormone (TSH) 2.24 Urea 17.8 Vitamin B12 204 White blood cells 7.5 HFD_index 0.309886873369003 CRP (mg/L) 20.3 CXCL11 (pg/ml) 1492.51447922401 CCL11 (pg/ml) not applicable IL17A (pg/ml) 4.709429886034 IFN-gamma (pg/ml) 30.5727666129918 IL-10 (pg/ml) 0.405800901597723 IL-6 (pg/ml) 2.40273352701656 IL-8 (pg/ml) 13.7217247655588 TNF-alpha (pg/ml) 8.66865892012035 CD4 (%) 7.64 CD8 (%) 21.5 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190733 SAMN10636416 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.003 host_residential_stratification LongStay treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 84 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 5 host_body_mass_index 27.3 collection_date 2015-08-10 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 27.3 Weight (kg) 90.5 Appendix A - Charlson co-morbidity 5 Appendix B - Barthel Score 5 Appendix C - FIM 51 Alkaline Phosphatase 114 ALT 15 AST 24 Billirubin 7 Cholesterol 3.5 High Density Lipoprotein(HDL) 0.75 Low Density Lipoprotein (LDL) 2.4 Triglycerides 0.97 Glucose 5.3 Creatinine 153 Ferritin 294 Thyroid Stimulating Hormone (TSH) 3.91 Urea 18.8 Vitamin B12 174 White blood cells 3.8 HFD_index 0.287601594043177 CRP (mg/L) 98.1 CXCL11 (pg/ml) 1271.6953687966 CCL11 (pg/ml) 203.269176978692 IL17A (pg/ml) 0.928406912065757 IFN-gamma (pg/ml) 19.3197647297409 IL-10 (pg/ml) 0.53503892753107 IL-6 (pg/ml) 5.26503760710722 IL-8 (pg/ml) 16.1241479609189 TNF-alpha (pg/ml) 4.40327831337294 CD4 (%) 39.1 CD8 (%) 4.08 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190734 SAMN10636417 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.004 host_residential_stratification LongStay treatment Placebo time_point week0 host Homo sapiens isolate Stool age not applicable host_age 79 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 4 host_body_mass_index 40 collection_date 2014-12-11 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 40 Weight (kg) 107.5 Appendix A - Charlson co-morbidity 8 Appendix B - Barthel Score 4 Appendix C - FIM 37 Alkaline Phosphatase 105 ALT 9 AST 18 Billirubin 6 Cholesterol 7 High Density Lipoprotein(HDL) 1.2 Low Density Lipoprotein (LDL) not collected Triglycerides 4.98 Glucose 6 Creatinine 162 Ferritin 52 Thyroid Stimulating Hormone (TSH) 2.24 Urea 17.4 Vitamin B12 246 White blood cells 6.4 HFD_index not collected CRP (mg/L) 9.4 CXCL11 (pg/ml) 1910.55032500584 CCL11 (pg/ml) not applicable IL17A (pg/ml) 5.30648498458724 IFN-gamma (pg/ml) 12.1283876268462 IL-10 (pg/ml) 0.471326930017903 IL-6 (pg/ml) 1.75082391665423 IL-8 (pg/ml) 14.8954756957011 TNF-alpha (pg/ml) 7.86068852597706 CD4 (%) 43.6 CD8 (%) 24.8 LPS (EU/ml) 6.71292518592777 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190735 SAMN10636415 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.003 host_residential_stratification LongStay treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 84 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 5 host_body_mass_index 26.8 collection_date 2015-04-22 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 26.8 Weight (kg) 88.8 Appendix A - Charlson co-morbidity 5 Appendix B - Barthel Score 5 Appendix C - FIM 68 Alkaline Phosphatase 90 ALT 10 AST 21 Billirubin 7 Cholesterol 4.1 High Density Lipoprotein(HDL) 0.72 Low Density Lipoprotein (LDL) 2.9 Triglycerides 1.18 Glucose 4.3 Creatinine 155 Ferritin 104 Thyroid Stimulating Hormone (TSH) 4.82 Urea 15.2 Vitamin B12 238 White blood cells 2.8 HFD_index 0.285522903532297 CRP (mg/L) 2.5 CXCL11 (pg/ml) 877.656900636593 CCL11 (pg/ml) 352.234485943556 IL17A (pg/ml) 0.705535761338494 IFN-gamma (pg/ml) 9.6053831468812 IL-10 (pg/ml) 0.451767205409584 IL-6 (pg/ml) 1.53504082819116 IL-8 (pg/ml) 10.5566485277862 TNF-alpha (pg/ml) 4.6320798195683 CD4 (%) 36.9 CD8 (%) 8.19 LPS (EU/ml) 20.6513883384235 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190736 SAMN10636382 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.025 host_residential_stratification Community treatment Placebo time_point week0 host Homo sapiens isolate Stool age not applicable host_age 66 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 25.8 collection_date 2016-04-14 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 25.8 Weight (kg) 64.4 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 52 ALT 19 AST not collected Billirubin 21 Cholesterol 4.6 High Density Lipoprotein(HDL) 1.57 Low Density Lipoprotein (LDL) 2.5 Triglycerides 1.03 Glucose 4.9 Creatinine 84 Ferritin 85 Thyroid Stimulating Hormone (TSH) 0.87 Urea 5.5 Vitamin B12 421 White blood cells 5 HFD_index 0.602232189653014 CRP (mg/L) 1.7 CXCL11 (pg/ml) 74.0536761786776 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.851029632219474 IFN-gamma (pg/ml) 0.852974636178107 IL-10 (pg/ml) 0.16354880815619 IL-6 (pg/ml) 0 IL-8 (pg/ml) 0.207701905303794 TNF-alpha (pg/ml) 0.604152810277184 CD4 (%) 30.5 CD8 (%) 15.2 LPS (EU/ml) 8.76961189099917 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190737 SAMN10636514 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.013 host_residential_stratification YoungHealthy treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 55 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index missing collection_date missing env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index not collected Weight (kg) 0 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase not collected ALT not collected AST not collected Billirubin not collected Cholesterol not collected High Density Lipoprotein(HDL) not collected Low Density Lipoprotein (LDL) not collected Triglycerides not collected Glucose not collected Creatinine not collected Ferritin not collected Thyroid Stimulating Hormone (TSH) not collected Urea not collected Vitamin B12 not collected White blood cells not collected HFD_index not collected CRP (mg/L) 0 CXCL11 (pg/ml) 454.557317340452 CCL11 (pg/ml) 14.7234346303634 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 3.08397168405497 IL-10 (pg/ml) 0.126276148227698 IL-6 (pg/ml) 0.298962792666313 IL-8 (pg/ml) 12.9337440754341 TNF-alpha (pg/ml) 1.02914490783809 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 5.18852459016393 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190738 SAMN10636513 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.013 host_residential_stratification YoungHealthy treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 55 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 24.5 collection_date 2015-11-09 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.5 Weight (kg) 65 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 81 ALT 14 AST not collected Billirubin 10 Cholesterol 6.3 High Density Lipoprotein(HDL) 1.45 Low Density Lipoprotein (LDL) 4.3 Triglycerides 1.32 Glucose 4.5 Creatinine 59 Ferritin 59 Thyroid Stimulating Hormone (TSH) not collected Urea 7.7 Vitamin B12 227 White blood cells 3.8 HFD_index 0.470006449004011 CRP (mg/L) 0.2 CXCL11 (pg/ml) 554.394929100052 CCL11 (pg/ml) 6.04425844181415 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 7.15024449362277 IL-10 (pg/ml) 0.171784470838337 IL-6 (pg/ml) 0.298962792666313 IL-8 (pg/ml) 11.4987318095301 TNF-alpha (pg/ml) 1.11044872701872 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 4.57377049180327 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190739 SAMN10636424 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.007 host_residential_stratification LongStay treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 71 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 0 host_body_mass_index 24 collection_date 2015-04-21 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24 Weight (kg) 63.3 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 0 Appendix C - FIM 17 Alkaline Phosphatase 106 ALT 8 AST 16 Billirubin 4 Cholesterol 4 High Density Lipoprotein(HDL) 0.79 Low Density Lipoprotein (LDL) 2 Triglycerides 2.56 Glucose 6 Creatinine 92 Ferritin 107 Thyroid Stimulating Hormone (TSH) 1.75 Urea 6.8 Vitamin B12 241 White blood cells 8.9 HFD_index 0.301446696728422 CRP (mg/L) 17.5 CXCL11 (pg/ml) 430.52959005216 CCL11 (pg/ml) 205.051387303917 IL17A (pg/ml) 6.65998064604241 IFN-gamma (pg/ml) 20.2590187380282 IL-10 (pg/ml) 0.588481933968581 IL-6 (pg/ml) 3.068260875715 IL-8 (pg/ml) 178.17772880842 TNF-alpha (pg/ml) 9.1684172626921 CD4 (%) 31.6 CD8 (%) 39.2999999999999 LPS (EU/ml) 31.2533513626932 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190740 SAMN10636506 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.008 host_residential_stratification YoungHealthy treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 28 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 20.1 collection_date 2016-01-20 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 20.1 Weight (kg) 58 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 45 ALT 13 AST 24 Billirubin 8 Cholesterol 6.5 High Density Lipoprotein(HDL) 2.45 Low Density Lipoprotein (LDL) 3.8 Triglycerides 0.73 Glucose 3.7 Creatinine 81 Ferritin 18 Thyroid Stimulating Hormone (TSH) 1.63 Urea 3.8 Vitamin B12 215 White blood cells 4.4 HFD_index 0.520757174942167 CRP (mg/L) 0.5 CXCL11 (pg/ml) not collected CCL11 (pg/ml) not collected IL17A (pg/ml) not collected IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) 42.1 CD8 (%) 17.2 LPS (EU/ml) 9.98360655737704 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190741 SAMN10636563 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.029 host_residential_stratification YoungHealthy treatment Placebo time_point week13 host Homo sapiens isolate Stool age not applicable host_age 22 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 20.5 collection_date 2016-05-13 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 20.5 Weight (kg) 70 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 66 ALT 29 AST 26 Billirubin 20 Cholesterol 6.8 High Density Lipoprotein(HDL) 2.05 Low Density Lipoprotein (LDL) 4.4 Triglycerides 0.86 Glucose 4.6 Creatinine 88 Ferritin 96 Thyroid Stimulating Hormone (TSH) 1.4 Urea 5.2 Vitamin B12 136 White blood cells 5.6 HFD_index 0.369366738891836 CRP (mg/L) 0.2 CXCL11 (pg/ml) 1284.61298340973 CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 2.2769541172051 IL-10 (pg/ml) 0.156524738264021 IL-6 (pg/ml) 0 IL-8 (pg/ml) 6.79625405559542 TNF-alpha (pg/ml) 1.73554944169657 CD4 (%) 36.5 CD8 (%) 29.9 LPS (EU/ml) 12.7870813397129 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190742 SAMN10636564 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.029 host_residential_stratification YoungHealthy treatment Placebo time_point week26 host Homo sapiens isolate Stool age not applicable host_age 22 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 20.5 collection_date 2016-08-09 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 20.5 Weight (kg) 70 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 84 ALT 23 AST 25 Billirubin 16 Cholesterol 5.4 High Density Lipoprotein(HDL) 1.69 Low Density Lipoprotein (LDL) 3.2 Triglycerides 1.12 Glucose 4.7 Creatinine 84 Ferritin 85 Thyroid Stimulating Hormone (TSH) 0.8 Urea 6 Vitamin B12 212 White blood cells 5.7 HFD_index 0.41563053320597 CRP (mg/L) 0.3 CXCL11 (pg/ml) 924.927113881421 CCL11 (pg/ml) 0 IL17A (pg/ml) 6.18276718125302e-09 IFN-gamma (pg/ml) 5.14726643620447 IL-10 (pg/ml) 0.215022776293384 IL-6 (pg/ml) 0 IL-8 (pg/ml) 7.90060552288303 TNF-alpha (pg/ml) 1.76043126724766 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 12.1590909090909 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190743 SAMN10636493 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.003 host_residential_stratification YoungHealthy treatment Placebo time_point week32 host Homo sapiens isolate Stool age not applicable host_age 31 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 24.4 collection_date 2016-05-25 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.4 Weight (kg) 69 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 139 ALT 30 AST 63 Billirubin 8 Cholesterol 3.8 High Density Lipoprotein(HDL) 1.25 Low Density Lipoprotein (LDL) 2.3 Triglycerides 0.74 Glucose 4.7 Creatinine 70 Ferritin 9 Thyroid Stimulating Hormone (TSH) 0.91 Urea 4.4 Vitamin B12 338 White blood cells 4.7 HFD_index 0.433997138322429 CRP (mg/L) 2.5 CXCL11 (pg/ml) 323.113594304047 CCL11 (pg/ml) 13.7009299417877 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 2.53324077012109 IL-10 (pg/ml) 0.0723203926497909 IL-6 (pg/ml) 0 IL-8 (pg/ml) 6.70502999951745 TNF-alpha (pg/ml) 0.613468497536559 CD4 (%) 30.3 CD8 (%) 27.6 LPS (EU/ml) 6.77936959410626 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190744 SAMN10636494 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.004 host_residential_stratification YoungHealthy treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 30 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 22.5 collection_date 2015-10-29 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 22.5 Weight (kg) 65 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 40 ALT 12 AST 20 Billirubin 13 Cholesterol 6.3 High Density Lipoprotein(HDL) 1.99 Low Density Lipoprotein (LDL) 3.6 Triglycerides 1.54 Glucose 5.6 Creatinine 64 Ferritin 31 Thyroid Stimulating Hormone (TSH) 2.97 Urea 3.7 Vitamin B12 222 White blood cells 6.7 HFD_index 0.436691860077937 CRP (mg/L) 4 CXCL11 (pg/ml) 0 CCL11 (pg/ml) 14.07864556239 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 17.0888873104279 IL-10 (pg/ml) 0.193580515390346 IL-6 (pg/ml) 0.0963523101623921 IL-8 (pg/ml) 9.0961233154525 TNF-alpha (pg/ml) 0.559074684790839 CD4 (%) 42.2 CD8 (%) 25.8 LPS (EU/ml) 6.68879537453663 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190745 SAMN10636520 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.015 host_residential_stratification YoungHealthy treatment Placebo time_point week13 host Homo sapiens isolate Stool age not applicable host_age 24 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 23.8 collection_date 2016-02-19 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23.8 Weight (kg) 84 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 68 ALT 22 AST 24 Billirubin 9 Cholesterol 3.7 High Density Lipoprotein(HDL) 1.01 Low Density Lipoprotein (LDL) 2.4 Triglycerides 0.62 Glucose 6.4 Creatinine 99 Ferritin 107 Thyroid Stimulating Hormone (TSH) 1.7 Urea 4.3 Vitamin B12 314 White blood cells 7.1 HFD_index 0.486553540102434 CRP (mg/L) 13 CXCL11 (pg/ml) 40.0677577480543 CCL11 (pg/ml) 2.88689560730018 IL17A (pg/ml) 0.0145948992494135 IFN-gamma (pg/ml) 15.6280887143428 IL-10 (pg/ml) 0.346043207046254 IL-6 (pg/ml) 1.29896215082034 IL-8 (pg/ml) 7.36844316769663 TNF-alpha (pg/ml) 2.27392005618464 CD4 (%) 38 CD8 (%) 14.9 LPS (EU/ml) 11.2131147540983 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190746 SAMN10636508 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.008 host_residential_stratification YoungHealthy treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 28 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 20.1 collection_date 2016-05-30 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 20.1 Weight (kg) 58 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 46 ALT 10 AST 21 Billirubin 7 Cholesterol 5.7 High Density Lipoprotein(HDL) 2.06 Low Density Lipoprotein (LDL) not collected Triglycerides 1.48 Glucose 4.3 Creatinine 75 Ferritin 8 Thyroid Stimulating Hormone (TSH) 2.67 Urea 3.4 Vitamin B12 133 White blood cells 4.2 HFD_index 0.586529540739614 CRP (mg/L) 2.5 CXCL11 (pg/ml) 19.4906397717864 CCL11 (pg/ml) 5.16681821771668 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 24.4648232982703 IL-10 (pg/ml) 0.313723049652314 IL-6 (pg/ml) 0.199890011578735 IL-8 (pg/ml) 15.0762341739125 TNF-alpha (pg/ml) 0.885556614202064 CD4 (%) 46.7 CD8 (%) 17.8 LPS (EU/ml) 9.85245901639344 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190747 SAMN10636413 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.002 host_residential_stratification LongStay treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 73 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 7 host_body_mass_index 32 collection_date 2015-09-01 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 32 Weight (kg) 94.8 Appendix A - Charlson co-morbidity 3 Appendix B - Barthel Score 7 Appendix C - FIM 69 Alkaline Phosphatase 136 ALT 11 AST 17 Billirubin 10 Cholesterol 3 High Density Lipoprotein(HDL) 0.77 Low Density Lipoprotein (LDL) 1.5 Triglycerides 1.61 Glucose 6.3 Creatinine 89 Ferritin 25 Thyroid Stimulating Hormone (TSH) 2.95 Urea 5.3 Vitamin B12 388 White blood cells 4.3 HFD_index 0.241583104152582 CRP (mg/L) 2.5 CXCL11 (pg/ml) 1900.16024082668 CCL11 (pg/ml) 341.549248884878 IL17A (pg/ml) 0.649669719711916 IFN-gamma (pg/ml) 2.83956859322718 IL-10 (pg/ml) 0.258038759903749 IL-6 (pg/ml) 0.699858365823613 IL-8 (pg/ml) 17.3910925695525 TNF-alpha (pg/ml) 2.36869134708584 CD4 (%) 45.4 CD8 (%) 28.2 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190748 SAMN10636414 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.003 host_residential_stratification LongStay treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 84 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 5 host_body_mass_index 29 collection_date 2014-12-11 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 29 Weight (kg) 94.3 Appendix A - Charlson co-morbidity 4 Appendix B - Barthel Score 5 Appendix C - FIM 68 Alkaline Phosphatase 105 ALT 11 AST 22 Billirubin 8 Cholesterol 3.8 High Density Lipoprotein(HDL) not collected Low Density Lipoprotein (LDL) not collected Triglycerides No sample Glucose 5.2 Creatinine 138 Ferritin 138 Thyroid Stimulating Hormone (TSH) No sample Urea 10.9 Vitamin B12 176 White blood cells 3.7 HFD_index not collected CRP (mg/L) 7.8 CXCL11 (pg/ml) 977.800674137301 CCL11 (pg/ml) 183.906707488325 IL17A (pg/ml) 4.165704899014 IFN-gamma (pg/ml) 8.30125903282229 IL-10 (pg/ml) 0.38364560868757003 IL-6 (pg/ml) 2.7041204477448 IL-8 (pg/ml) 6.22074991070519 TNF-alpha (pg/ml) 3.92668320993108 CD4 (%) 42.4 CD8 (%) 4.37 LPS (EU/ml) 6.7024339635838 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190749 SAMN10636411 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.002 host_residential_stratification LongStay treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 72 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 9 host_body_mass_index 31.9 collection_date 2015-04-22 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 31.9 Weight (kg) 94.4 Appendix A - Charlson co-morbidity 3 Appendix B - Barthel Score 9 Appendix C - FIM 71 Alkaline Phosphatase 132 ALT 10 AST 17 Billirubin 8 Cholesterol 3.5 High Density Lipoprotein(HDL) 0.81 Low Density Lipoprotein (LDL) 2 Triglycerides 1.54 Glucose 8.1 Creatinine 84 Ferritin 29 Thyroid Stimulating Hormone (TSH) 2.29 Urea 5.7 Vitamin B12 1500 White blood cells 5.8 HFD_index 0.227615514240904 CRP (mg/L) 2.5 CXCL11 (pg/ml) 1499.10920162501 CCL11 (pg/ml) 444.995926967366 IL17A (pg/ml) 0.844932112477592 IFN-gamma (pg/ml) 3.52674110341322 IL-10 (pg/ml) 0.158360876883166 IL-6 (pg/ml) 1.38659776716063 IL-8 (pg/ml) 11.7337913592771 TNF-alpha (pg/ml) 3.13734202646775 CD4 (%) 14.1 CD8 (%) 23.2 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190750 SAMN10636412 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.002 host_residential_stratification LongStay treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 72 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 8 host_body_mass_index 32 collection_date 2015-08-10 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 32 Weight (kg) 95.2 Appendix A - Charlson co-morbidity 3 Appendix B - Barthel Score 8 Appendix C - FIM 69 Alkaline Phosphatase 150 ALT 12 AST 17 Billirubin 9 Cholesterol 3.5 High Density Lipoprotein(HDL) 0.78 Low Density Lipoprotein (LDL) 2 Triglycerides 1.59 Glucose 7.2 Creatinine 83 Ferritin 30 Thyroid Stimulating Hormone (TSH) 2.51 Urea 5.6 Vitamin B12 861 White blood cells 4.6 HFD_index 0.241583104152582 CRP (mg/L) 2.5 CXCL11 (pg/ml) 1574.72268621819 CCL11 (pg/ml) 341.138556651193 IL17A (pg/ml) 0.705535761338494 IFN-gamma (pg/ml) 8.65195101595172 IL-10 (pg/ml) 0.264892002137393 IL-6 (pg/ml) 1.03823608985887 IL-8 (pg/ml) 15.438224951692 TNF-alpha (pg/ml) 3.11523062561053 CD4 (%) 1.88 CD8 (%) 29 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190751 SAMN10636409 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.001 host_residential_stratification LongStay treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 83 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 1 host_body_mass_index 23.7 collection_date 2015-09-04 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23.7 Weight (kg) 64.4 Appendix A - Charlson co-morbidity 3 Appendix B - Barthel Score 1 Appendix C - FIM 25 Alkaline Phosphatase not collected ALT not collected AST not collected Billirubin not collected Cholesterol not collected High Density Lipoprotein(HDL) not collected Low Density Lipoprotein (LDL) not collected Triglycerides not collected Glucose not collected Creatinine not collected Ferritin not collected Thyroid Stimulating Hormone (TSH) not collected Urea not collected Vitamin B12 not collected White blood cells not collected HFD_index 0.427197359487794 CRP (mg/L) 0 CXCL11 (pg/ml) 2174.93338679971 CCL11 (pg/ml) 518.112013094865 IL17A (pg/ml) 39.3878027424886 IFN-gamma (pg/ml) 2.41203417402853 IL-10 (pg/ml) 0.19366501496561 IL-6 (pg/ml) 1.61261759892336 IL-8 (pg/ml) 20.3228121861438 TNF-alpha (pg/ml) 2.3605878988944 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 8.23299452697419 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190752 SAMN10636410 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.002 host_residential_stratification LongStay treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 72 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 9 host_body_mass_index 31 collection_date 2014-12-05 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 31 Weight (kg) 96.4 Appendix A - Charlson co-morbidity 2 Appendix B - Barthel Score 9 Appendix C - FIM 71 Alkaline Phosphatase 141 ALT 12 AST 18 Billirubin 10 Cholesterol 3.8 High Density Lipoprotein(HDL) - Low Density Lipoprotein (LDL) not collected Triglycerides No sample Glucose 9 Creatinine 93 Ferritin 28 Thyroid Stimulating Hormone (TSH) No sample Urea 6.5 Vitamin B12 74 White blood cells 6 HFD_index not collected CRP (mg/L) 2.5 CXCL11 (pg/ml) 1652.98920032491 CCL11 (pg/ml) 583.777006842483 IL17A (pg/ml) 0.340942686666844 IFN-gamma (pg/ml) 4.0572554307087 IL-10 (pg/ml) 0.170426418802249 IL-6 (pg/ml) 3.618313966245 IL-8 (pg/ml) 7.22817836367593 TNF-alpha (pg/ml) 2.7285491556135 CD4 (%) 49.5 CD8 (%) 30.8 LPS (EU/ml) 6.68821252885086 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190753 SAMN10636407 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.001 host_residential_stratification LongStay treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 82 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 0 host_body_mass_index 23.2 collection_date 2015-04-22 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23.2 Weight (kg) 63.1 Appendix A - Charlson co-morbidity 3 Appendix B - Barthel Score 0 Appendix C - FIM 27 Alkaline Phosphatase not collected ALT not collected AST not collected Billirubin not collected Cholesterol not collected High Density Lipoprotein(HDL) not collected Low Density Lipoprotein (LDL) not collected Triglycerides not collected Glucose not collected Creatinine 23 Ferritin not collected Thyroid Stimulating Hormone (TSH) not collected Urea 5.3 Vitamin B12 not collected White blood cells 9.9 HFD_index 0.444568048555572 CRP (mg/L) 19.8999999999999 CXCL11 (pg/ml) not collected CCL11 (pg/ml) not collected IL17A (pg/ml) not collected IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190754 SAMN10636408 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.001 host_residential_stratification LongStay treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 83 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 0 host_body_mass_index 23 collection_date 2015-07-28 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23 Weight (kg) 63.3 Appendix A - Charlson co-morbidity 3 Appendix B - Barthel Score 0 Appendix C - FIM 26 Alkaline Phosphatase not collected ALT not collected AST not collected Billirubin not collected Cholesterol not collected High Density Lipoprotein(HDL) not collected Low Density Lipoprotein (LDL) not collected Triglycerides not collected Glucose not collected Creatinine not collected Ferritin not collected Thyroid Stimulating Hormone (TSH) not collected Urea not collected Vitamin B12 not collected White blood cells not collected HFD_index 0.427197359487794 CRP (mg/L) 0 CXCL11 (pg/ml) not collected CCL11 (pg/ml) not collected IL17A (pg/ml) not collected IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190755 SAMN10636405 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.030 host_residential_stratification Community treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 66 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 28.9 collection_date 2017-01-25 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 28.9 Weight (kg) 88.5 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase not collected ALT not collected AST not collected Billirubin not collected Cholesterol not collected High Density Lipoprotein(HDL) not collected Low Density Lipoprotein (LDL) not collected Triglycerides not collected Glucose 5.5 Creatinine not collected Ferritin 27 Thyroid Stimulating Hormone (TSH) not collected Urea not collected Vitamin B12 122 White blood cells 4 HFD_index 0.540742991561328 CRP (mg/L) not collected CXCL11 (pg/ml) 2005.2229849118 CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 2.11153078463504 IL-10 (pg/ml) 0.143967660399096 IL-6 (pg/ml) 0.106023618899791 IL-8 (pg/ml) 16.9323443626671 TNF-alpha (pg/ml) 0.978229843221057 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 9.76052848885218 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190756 SAMN10636406 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.001 host_residential_stratification LongStay treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 82 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 0 host_body_mass_index 25 collection_date 2014-12-05 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 25 Weight (kg) 66.2 Appendix A - Charlson co-morbidity 3 Appendix B - Barthel Score 0 Appendix C - FIM 27 Alkaline Phosphatase 82 ALT 19 AST not collected Billirubin 6 Cholesterol 5.3 High Density Lipoprotein(HDL) - Low Density Lipoprotein (LDL) N/A Triglycerides No sample Glucose 9.8 Creatinine 21 Ferritin 26 Thyroid Stimulating Hormone (TSH) No sample Urea 4.9 Vitamin B12 217 White blood cells 8.9 HFD_index not collected CRP (mg/L) not collected CXCL11 (pg/ml) not collected CCL11 (pg/ml) not collected IL17A (pg/ml) not collected IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190757 SAMN10636390 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.027 host_residential_stratification Community treatment Placebo time_point week0 host Homo sapiens isolate Stool age not applicable host_age 83 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 24.1 collection_date 2016-05-18 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.1 Weight (kg) 55 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 125 Alkaline Phosphatase 58 ALT 22 AST not collected Billirubin 11 Cholesterol 5 High Density Lipoprotein(HDL) 1.6 Low Density Lipoprotein (LDL) 2.9 Triglycerides 1.05 Glucose 5.4 Creatinine 71 Ferritin 107 Thyroid Stimulating Hormone (TSH) 3.44 Urea 4.7 Vitamin B12 217 White blood cells 5 HFD_index 0.430247696525615 CRP (mg/L) 1.5 CXCL11 (pg/ml) 44.8630997455249 CCL11 (pg/ml) 107.770062793224 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 2.49053437088889 IL-10 (pg/ml) 0.101498565259654 IL-6 (pg/ml) 0.818096129578426 IL-8 (pg/ml) 6.29635028807636 TNF-alpha (pg/ml) 0.80271241275529 CD4 (%) 52.9 CD8 (%) 6.66 LPS (EU/ml) 5.42526837324525 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190758 SAMN10636544 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.023 host_residential_stratification YoungHealthy treatment Placebo time_point week13 host Homo sapiens isolate Stool age not applicable host_age 26 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 28.7 collection_date 2016-05-04 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 28.7 Weight (kg) 93 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 80 ALT 29 AST 28 Billirubin 11 Cholesterol 5 High Density Lipoprotein(HDL) 1.26 Low Density Lipoprotein (LDL) 3.3 Triglycerides 0.79 Glucose 2.7 Creatinine 92 Ferritin 157 Thyroid Stimulating Hormone (TSH) 1.91 Urea 4.7 Vitamin B12 336 White blood cells 4.4 HFD_index 0.589031477177463 CRP (mg/L) 0.4 CXCL11 (pg/ml) not applicable CCL11 (pg/ml) 24.3396672176794 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 3.14542403045056 IL-10 (pg/ml) 0.196564370808971 IL-6 (pg/ml) 0.151090308794974 IL-8 (pg/ml) 6.67698040685256 TNF-alpha (pg/ml) 2.34246523977784 CD4 (%) 24.3 CD8 (%) 23.2 LPS (EU/ml) 7.0327868852459 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190759 SAMN10636313 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.005 host_residential_stratification Community treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 67 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 35.7 collection_date 2016-05-09 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 35.7 Weight (kg) 91.5 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 93 ALT 17 AST 21 Billirubin 9 Cholesterol 5.8 High Density Lipoprotein(HDL) 1.52 Low Density Lipoprotein (LDL) 3.9 Triglycerides 0.94 Glucose 4.6 Creatinine 59 Ferritin 75 Thyroid Stimulating Hormone (TSH) 6.31 Urea 7.3 Vitamin B12 268 White blood cells 4.8 HFD_index 0.444789789494304 CRP (mg/L) 3.4 CXCL11 (pg/ml) 466.06610035031 CCL11 (pg/ml) 0 IL17A (pg/ml) 1.23020091789392 IFN-gamma (pg/ml) 13.3282597949319 IL-10 (pg/ml) 0.196937966274634 IL-6 (pg/ml) 0.75009997810742 IL-8 (pg/ml) 9.43382331534309 TNF-alpha (pg/ml) 2.5203319846914 CD4 (%) not collected CD8 (%) 14.7 LPS (EU/ml) 7.15937241948802 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190760 SAMN10636314 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.005 host_residential_stratification Community treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 67 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 34.8 collection_date 2016-06-20 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 34.8 Weight (kg) 89 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 90 ALT 19 AST 19 Billirubin 10 Cholesterol 6.3 High Density Lipoprotein(HDL) 1.38 Low Density Lipoprotein (LDL) 4.5 Triglycerides 0.83 Glucose 4.4 Creatinine 63 Ferritin not collected Thyroid Stimulating Hormone (TSH) 4.17 Urea 7.1 Vitamin B12 not collected White blood cells 4.4 HFD_index 0.444789789494304 CRP (mg/L) 4.2 CXCL11 (pg/ml) 607.065454140469 CCL11 (pg/ml) 94.4901463357615 IL17A (pg/ml) 0.873283176849578 IFN-gamma (pg/ml) 16.2242133951888 IL-10 (pg/ml) 0.180745702486101 IL-6 (pg/ml) 0.815489340315462 IL-8 (pg/ml) 11.5307144929091 TNF-alpha (pg/ml) 1.58767105485492 CD4 (%) 34 CD8 (%) 19 LPS (EU/ml) 7.15937241948802 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190761 SAMN10636309 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.004 host_residential_stratification Community treatment Placebo time_point week26 host Homo sapiens isolate Stool age not applicable host_age 79 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 24.6 collection_date 2016-05-25 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.6 Weight (kg) 55 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 87 ALT 29 AST 46 Billirubin 12 Cholesterol 5.9 High Density Lipoprotein(HDL) 3.16 Low Density Lipoprotein (LDL) 2.4 Triglycerides 0.75 Glucose 5.2 Creatinine 45 Ferritin 40 Thyroid Stimulating Hormone (TSH) 3.12 Urea 4.5 Vitamin B12 303 White blood cells 4.3 HFD_index 0.390939353051986 CRP (mg/L) 0.3 CXCL11 (pg/ml) 5016.80241666091 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.750151552765842 IFN-gamma (pg/ml) 8.07528059418864 IL-10 (pg/ml) 0.360292323365882 IL-6 (pg/ml) 3.19978069269712 IL-8 (pg/ml) 18.1586521095485 TNF-alpha (pg/ml) 1.51884281414962 CD4 (%) 19.7 CD8 (%) 9.32 LPS (EU/ml) 9.01734104046242 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190762 SAMN10636310 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.004 host_residential_stratification Community treatment Placebo time_point week32 host Homo sapiens isolate Stool age not applicable host_age 79 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 19 host_body_mass_index 24.1 collection_date 2016-07-21 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.1 Weight (kg) 54 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 19 Appendix C - FIM 125 Alkaline Phosphatase 91 ALT 27 AST not collected Billirubin 16 Cholesterol 6.5 High Density Lipoprotein(HDL) 3.38 Low Density Lipoprotein (LDL) 2.7 Triglycerides 0.88 Glucose 4.6 Creatinine 52 Ferritin 53 Thyroid Stimulating Hormone (TSH) 2.3 Urea 4.4 Vitamin B12 359 White blood cells 3.3 HFD_index 0.417285003977717 CRP (mg/L) 0.4 CXCL11 (pg/ml) 0 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.73614513405958 IFN-gamma (pg/ml) 5.10992638119854 IL-10 (pg/ml) 0.159682667680481 IL-6 (pg/ml) 2.98378899916192 IL-8 (pg/ml) 17.64723629251 TNF-alpha (pg/ml) 1.02419965924543 CD4 (%) 34.2 CD8 (%) 3.59 LPS (EU/ml) 5.42526837324525 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190763 SAMN10636311 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.005 host_residential_stratification Community treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 66 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 35.3 collection_date 2015-11-09 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 35.3 Weight (kg) 90.3 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 87 ALT 15 AST 18 Billirubin 9 Cholesterol 6.4 High Density Lipoprotein(HDL) 1.62 Low Density Lipoprotein (LDL) 4.4 Triglycerides 0.84 Glucose 4.3 Creatinine 67 Ferritin 78 Thyroid Stimulating Hormone (TSH) 6 Urea 6.3 Vitamin B12 243 White blood cells 4.3 HFD_index 0.351842035339773 CRP (mg/L) 2.4 CXCL11 (pg/ml) 152.674080888401 CCL11 (pg/ml) 0 IL17A (pg/ml) 2.15498261878374 IFN-gamma (pg/ml) 20.5766799713906 IL-10 (pg/ml) 0.168528970109723 IL-6 (pg/ml) 1.0758191001564 IL-8 (pg/ml) 12.5865483715777 TNF-alpha (pg/ml) 1.45146289029854 CD4 (%) 31 CD8 (%) 20 LPS (EU/ml) 6.91164327002477 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190764 SAMN10636312 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.005 host_residential_stratification Community treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 66 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 35.2 collection_date 2016-02-08 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 35.2 Weight (kg) 90 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 95 ALT 18 AST 21 Billirubin 5 Cholesterol 6.2 High Density Lipoprotein(HDL) 1.57 Low Density Lipoprotein (LDL) 4.2 Triglycerides 0.89 Glucose 4.3 Creatinine 72 Ferritin 80 Thyroid Stimulating Hormone (TSH) 8.75 Urea 6.7 Vitamin B12 166 White blood cells 4.8 HFD_index 0.351842035339773 CRP (mg/L) 2.9 CXCL11 (pg/ml) 771.725935147842 CCL11 (pg/ml) 0 IL17A (pg/ml) 1.17395704704075 IFN-gamma (pg/ml) 17.7228784462197 IL-10 (pg/ml) 0.185760419841593 IL-6 (pg/ml) 0.73696934179175 IL-8 (pg/ml) 10.352027934634 TNF-alpha (pg/ml) 2.27804425923988 CD4 (%) 38.1 CD8 (%) 19.7 LPS (EU/ml) 7.65483071841453 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190765 SAMN10636305 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.003 host_residential_stratification Community treatment Placebo time_point week26 host Homo sapiens isolate Stool age not applicable host_age 76 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 25.3 collection_date 2016-05-04 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 25.3 Weight (kg) 65.5 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 75 ALT 14 AST 21 Billirubin 9 Cholesterol 5.6 High Density Lipoprotein(HDL) 1.48 Low Density Lipoprotein (LDL) 3.6 Triglycerides 1.13 Glucose 5.4 Creatinine 46 Ferritin 187 Thyroid Stimulating Hormone (TSH) 1.33 Urea 5.5 Vitamin B12 429 White blood cells 8.8 HFD_index 0.500011072564716 CRP (mg/L) 0.8 CXCL11 (pg/ml) 1809.33892789752 CCL11 (pg/ml) 87.3194975541172 IL17A (pg/ml) 0.918454463469531 IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) 41.3 CD8 (%) 11.5 LPS (EU/ml) 30.7917375795584 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190766 SAMN10636307 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.004 host_residential_stratification Community treatment Placebo time_point week0 host Homo sapiens isolate Stool age not applicable host_age 79 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 19 host_body_mass_index 24.1 collection_date 2015-11-12 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.1 Weight (kg) 55 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 19 Appendix C - FIM 124 Alkaline Phosphatase 91 ALT 37 AST 55 Billirubin 14 Cholesterol 7.4 High Density Lipoprotein(HDL) 4.5 Low Density Lipoprotein (LDL) 2.4 Triglycerides 1.15 Glucose 4.4 Creatinine 49 Ferritin 48 Thyroid Stimulating Hormone (TSH) 2.93 Urea 4.1 Vitamin B12 416 White blood cells 5.1 HFD_index 0.315982186815948 CRP (mg/L) 0.3 CXCL11 (pg/ml) 50.0384851476595 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.836317808076729 IFN-gamma (pg/ml) 2.64114473082263 IL-10 (pg/ml) 0.12248974908431 IL-6 (pg/ml) 1.56797459846638 IL-8 (pg/ml) 11.5189062585576 TNF-alpha (pg/ml) 1.8584932526062 CD4 (%) 47.1 CD8 (%) 4.61 LPS (EU/ml) 8.39801816680429 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190767 SAMN10636306 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.003 host_residential_stratification Community treatment Placebo time_point week32 host Homo sapiens isolate Stool age not applicable host_age 76 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 25.3 collection_date 2016-06-07 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 25.3 Weight (kg) 65.5 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 81 ALT 16 AST 25 Billirubin 9 Cholesterol 5 High Density Lipoprotein(HDL) 1.37 Low Density Lipoprotein (LDL) 3.2 Triglycerides 0.96 Glucose 5.1 Creatinine 45 Ferritin 190 Thyroid Stimulating Hormone (TSH) 1.29 Urea 4.1 Vitamin B12 390 White blood cells 7 HFD_index 0.505246743121459 CRP (mg/L) not collected CXCL11 (pg/ml) 4235.5635978545 CCL11 (pg/ml) 0 IL17A (pg/ml) 1.36634713856045 IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) 45.5 CD8 (%) 6.29 LPS (EU/ml) 30.9316205441447 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190768 SAMN10636308 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.004 host_residential_stratification Community treatment Placebo time_point week13 host Homo sapiens isolate Stool age not applicable host_age 79 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 19 host_body_mass_index 24.6 collection_date 2016-02-17 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.6 Weight (kg) 55.5 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 19 Appendix C - FIM 124 Alkaline Phosphatase 88 ALT 37 AST 57 Billirubin 9 Cholesterol 7 High Density Lipoprotein(HDL) 4.05 Low Density Lipoprotein (LDL) 2.6 Triglycerides 0.82 Glucose 4.9 Creatinine 46 Ferritin 45 Thyroid Stimulating Hormone (TSH) 2.77 Urea 4.4 Vitamin B12 406 White blood cells 4.1 HFD_index 0.333982222812871 CRP (mg/L) 0.3 CXCL11 (pg/ml) 106.479855822635 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.750151552765842 IFN-gamma (pg/ml) 29.7534021842524 IL-10 (pg/ml) 0.301639182378183 IL-6 (pg/ml) 5.94608001908927 IL-8 (pg/ml) 13.9320970256823 TNF-alpha (pg/ml) 1.62414930241052 CD4 (%) 54.2 CD8 (%) 4.26999999999999 LPS (EU/ml) 6.91164327002477 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190769 SAMN10636423 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.007 host_residential_stratification LongStay treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 71 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 0 host_body_mass_index 23 collection_date 2015-01-15 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23 Weight (kg) 63.6 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 0 Appendix C - FIM 17 Alkaline Phosphatase 106 ALT 15 AST 18 Billirubin 5 Cholesterol 4.3 High Density Lipoprotein(HDL) 0.96 Low Density Lipoprotein (LDL) 2.3 Triglycerides 2.12 Glucose 5.9 Creatinine 89 Ferritin 97 Thyroid Stimulating Hormone (TSH) 1.33 Urea 6.7 Vitamin B12 249 White blood cells 8.4 HFD_index not collected CRP (mg/L) 26.3 CXCL11 (pg/ml) 709.158876232279 CCL11 (pg/ml) 252.248038284302 IL17A (pg/ml) 13.6465062513281 IFN-gamma (pg/ml) 24.6310397738974 IL-10 (pg/ml) 0.48577743786197 IL-6 (pg/ml) 3.44397708005244 IL-8 (pg/ml) 321.695162371683 TNF-alpha (pg/ml) 13.9641686019509 CD4 (%) 24.3 CD8 (%) 49.8 LPS (EU/ml) 31.2953162520691 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190770 SAMN10636342 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.012 host_residential_stratification Community treatment Placebo time_point week32 host Homo sapiens isolate Stool age not applicable host_age 67 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 23.9 collection_date 2016-07-13 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23.9 Weight (kg) 65.9 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 103 ALT 23 AST 30 Billirubin 14 Cholesterol 5.3 High Density Lipoprotein(HDL) 1.27 Low Density Lipoprotein (LDL) 3.5 Triglycerides 1.04 Glucose 5.2 Creatinine 95 Ferritin 80 Thyroid Stimulating Hormone (TSH) 0.55 Urea 8.6 Vitamin B12 135 White blood cells 5.1 HFD_index 0.39589011715627 CRP (mg/L) 1.2 CXCL11 (pg/ml) 0 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.708440110273209 IFN-gamma (pg/ml) 2.92975911624104 IL-10 (pg/ml) 0.12248974908431 IL-6 (pg/ml) 0.0490664643628785 IL-8 (pg/ml) 13.2720899391215 TNF-alpha (pg/ml) 1.99168117760304 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190771 SAMN10636341 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.012 host_residential_stratification Community treatment Placebo time_point week26 host Homo sapiens isolate Stool age not applicable host_age 67 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 24.1 collection_date 2016-06-08 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.1 Weight (kg) 66.3 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 106 ALT 21 AST 28 Billirubin 16 Cholesterol 4.6 High Density Lipoprotein(HDL) 1.33 Low Density Lipoprotein (LDL) 2.9 Triglycerides 0.84 Glucose 5.7 Creatinine 101 Ferritin 93 Thyroid Stimulating Hormone (TSH) 0.39 Urea 7.2 Vitamin B12 158 White blood cells 5.8 HFD_index 0.350475345126608 CRP (mg/L) 9.69999999999999 CXCL11 (pg/ml) not collected CCL11 (pg/ml) 0 IL17A (pg/ml) 0.761901520793181 IFN-gamma (pg/ml) 2.33708497273216 IL-10 (pg/ml) 0.125742846071007 IL-6 (pg/ml) 0.359847078922263 IL-8 (pg/ml) 9.48990703248441 TNF-alpha (pg/ml) 1.62414930241052 CD4 (%) 48.2 CD8 (%) 14 LPS (EU/ml) 17.5657894736842 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190772 SAMN10636340 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.012 host_residential_stratification Community treatment Placebo time_point week13 host Homo sapiens isolate Stool age not applicable host_age 67 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 24.3 collection_date 2016-03-02 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.3 Weight (kg) 67 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 95 ALT 23 AST 25 Billirubin 8 Cholesterol 5.8 High Density Lipoprotein(HDL) 1.15 Low Density Lipoprotein (LDL) 3.9 Triglycerides 1.73 Glucose 5.5 Creatinine 91 Ferritin 99 Thyroid Stimulating Hormone (TSH) 0.23 Urea 7 Vitamin B12 284 White blood cells 5.2 HFD_index 0.344638342932191 CRP (mg/L) 0.5 CXCL11 (pg/ml) not collected CCL11 (pg/ml) not collected IL17A (pg/ml) not collected IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 17.6555023923445 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190773 SAMN10636339 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.012 host_residential_stratification Community treatment Placebo time_point week0 host Homo sapiens isolate Stool age not applicable host_age 67 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 24.7 collection_date 2015-12-09 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.7 Weight (kg) 68 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 96 ALT 27 AST not collected Billirubin 10 Cholesterol 5.5 High Density Lipoprotein(HDL) 1.25 Low Density Lipoprotein (LDL) 3.6 Triglycerides 1.49 Glucose 5.4 Creatinine 97 Ferritin 104 Thyroid Stimulating Hormone (TSH) 0.5 Urea 7.3 Vitamin B12 203 White blood cells 7.2 HFD_index 0.372341378948801 CRP (mg/L) 0.9 CXCL11 (pg/ml) 0 CCL11 (pg/ml) not collected IL17A (pg/ml) not collected IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) 0.71 CD8 (%) not collected LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190774 SAMN10636338 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.011 host_residential_stratification Community treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 72 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 23.6 collection_date 2016-05-20 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23.6 Weight (kg) 65 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 58 ALT 26 AST 27 Billirubin 10 Cholesterol 6.4 High Density Lipoprotein(HDL) 1.15 Low Density Lipoprotein (LDL) 4.4 Triglycerides 1.87 Glucose 3.1 Creatinine 71 Ferritin 171 Thyroid Stimulating Hormone (TSH) 1.04 Urea 7.5 Vitamin B12 421 White blood cells 5.8 HFD_index 0.639902453162698 CRP (mg/L) 0.8 CXCL11 (pg/ml) 0 CCL11 (pg/ml) 76.7658881897295 IL17A (pg/ml) 0.792781243002046 IFN-gamma (pg/ml) 5.98705396617672 IL-10 (pg/ml) 0.182973277639933 IL-6 (pg/ml) 0.200902608529124 IL-8 (pg/ml) 16.2597298275534 TNF-alpha (pg/ml) 2.33136040701083 CD4 (%) 61.4 CD8 (%) 8.8 LPS (EU/ml) 18.3732057416267 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190775 SAMN10636337 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.011 host_residential_stratification Community treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 72 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 24 collection_date 2016-04-08 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24 Weight (kg) 66 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 62 ALT 21 AST 28 Billirubin 12 Cholesterol 6.5 High Density Lipoprotein(HDL) 1.21 Low Density Lipoprotein (LDL) 4.1 Triglycerides 2.54 Glucose 4.4 Creatinine 73 Ferritin 165 Thyroid Stimulating Hormone (TSH) 1.47 Urea 7.9 Vitamin B12 475 White blood cells 6.3 HFD_index 0.639902453162698 CRP (mg/L) 1.5 CXCL11 (pg/ml) not collected CCL11 (pg/ml) not collected IL17A (pg/ml) not collected IFN-gamma (pg/ml) 13.9716466290469 IL-10 (pg/ml) 0.15362058963922 IL-6 (pg/ml) 0.334753415988233 IL-8 (pg/ml) 9.36257603860494 TNF-alpha (pg/ml) 1.80964412687622 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190776 SAMN10636336 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.011 host_residential_stratification Community treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 72 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 24 collection_date 2016-03-03 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24 Weight (kg) 66.1 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 52 ALT 17 AST 27 Billirubin 11 Cholesterol 6.7 High Density Lipoprotein(HDL) 1.2 Low Density Lipoprotein (LDL) 4.7 Triglycerides 1.66 Glucose 5.6 Creatinine 70 Ferritin 175 Thyroid Stimulating Hormone (TSH) 0.92 Urea 10.1 Vitamin B12 371 White blood cells 6.5 HFD_index 0.458844986970325 CRP (mg/L) 0.8 CXCL11 (pg/ml) 0 CCL11 (pg/ml) 88.5756072222516 IL17A (pg/ml) 0.841210707465428 IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) not collected CD8 (%) 10.6 LPS (EU/ml) 17.206937799043 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190777 SAMN10636335 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.011 host_residential_stratification Community treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 72 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 24.4 collection_date 2015-12-04 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.4 Weight (kg) 66.4 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 63 ALT 18 AST 23 Billirubin 9 Cholesterol 6.4 High Density Lipoprotein(HDL) 1.08 Low Density Lipoprotein (LDL) 4.4 Triglycerides 1.99 Glucose 5.4 Creatinine 69 Ferritin 121 Thyroid Stimulating Hormone (TSH) 1.89 Urea 7.5 Vitamin B12 381 White blood cells 6.4 HFD_index 0.458844986970325 CRP (mg/L) 0.7 CXCL11 (pg/ml) 3.8082230155207 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.807193214140544 IFN-gamma (pg/ml) 12.404269338419 IL-10 (pg/ml) 0.215477596422836 IL-6 (pg/ml) 0.267068883074851 IL-8 (pg/ml) 13.1317348228767 TNF-alpha (pg/ml) 2.51347688501645 CD4 (%) 52.1 CD8 (%) 8.97 LPS (EU/ml) 17.0275119617224 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190778 SAMN10636586 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.036 host_residential_stratification YoungHealthy treatment Placebo time_point week26 host Homo sapiens isolate Stool age not applicable host_age 61 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 25.3 collection_date 2016-10-04 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 25.3 Weight (kg) 64.7 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 89 ALT 14 AST 25 Billirubin 8 Cholesterol 6.6 High Density Lipoprotein(HDL) 1.44 Low Density Lipoprotein (LDL) 4.8 Triglycerides 0.81 Glucose 5.2 Creatinine 54 Ferritin 65 Thyroid Stimulating Hormone (TSH) 1.71 Urea 4.8 Vitamin B12 371 White blood cells 3.8 HFD_index not collected CRP (mg/L) 3.3 CXCL11 (pg/ml) not collected CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 0 IL-10 (pg/ml) 0 IL-6 (pg/ml) 0 IL-8 (pg/ml) 0 TNF-alpha (pg/ml) 0 CD4 (%) 39.2999999999999 CD8 (%) 12.6 LPS (EU/ml) 5.79686209744013 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190779 SAMN10636585 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.036 host_residential_stratification YoungHealthy treatment Placebo time_point week13 host Homo sapiens isolate Stool age not applicable host_age 60 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 25.8 collection_date 2016-07-12 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 25.8 Weight (kg) 66.5 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 89 ALT 38 AST 35 Billirubin 13 Cholesterol 9 High Density Lipoprotein(HDL) 1.99 Low Density Lipoprotein (LDL) 6.5 Triglycerides 1.02 Glucose 5.4 Creatinine 53 Ferritin 63 Thyroid Stimulating Hormone (TSH) 1.91 Urea 4.6 Vitamin B12 309 White blood cells 4.1 HFD_index 0.44712920995857 CRP (mg/L) 1.3 CXCL11 (pg/ml) not collected CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 0 IL-10 (pg/ml) 0 IL-6 (pg/ml) 0 IL-8 (pg/ml) 0 TNF-alpha (pg/ml) 0 CD4 (%) 33.4 CD8 (%) 9.18 LPS (EU/ml) 5.92072667199999 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190780 SAMN10636344 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.013 host_residential_stratification Community treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 66 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 26.2 collection_date 2016-03-04 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 26.2 Weight (kg) 63 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 112 ALT 19 AST 28 Billirubin 9 Cholesterol 6.8 High Density Lipoprotein(HDL) 2 Low Density Lipoprotein (LDL) 3.9 Triglycerides 2.07 Glucose 5.1 Creatinine 62 Ferritin 105 Thyroid Stimulating Hormone (TSH) 1.66 Urea 4.5 Vitamin B12 295 White blood cells 5.4 HFD_index 0.391322056783198 CRP (mg/L) not collected CXCL11 (pg/ml) not collected CCL11 (pg/ml) not collected IL17A (pg/ml) not collected IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) 44.1 CD8 (%) 17.2 LPS (EU/ml) 17.834928229665 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190781 SAMN10636587 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.036 host_residential_stratification YoungHealthy treatment Placebo time_point week32 host Homo sapiens isolate Stool age not applicable host_age 61 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 25 collection_date 2016-11-17 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 25 Weight (kg) 64 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 99 ALT 14 AST 28 Billirubin 10 Cholesterol 7.3 High Density Lipoprotein(HDL) 1.83 Low Density Lipoprotein (LDL) 5.1 Triglycerides 0.93 Glucose 4.7 Creatinine 56 Ferritin 56 Thyroid Stimulating Hormone (TSH) 1.33 Urea 6.1 Vitamin B12 367 White blood cells 4.2 HFD_index not collected CRP (mg/L) 1 CXCL11 (pg/ml) not collected CCL11 (pg/ml) not collected IL17A (pg/ml) not collected IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) 36.2 CD8 (%) 8.81 LPS (EU/ml) 6.54004954582989 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190782 SAMN10636320 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.007 host_residential_stratification Community treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 71 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 26.4 collection_date 2016-02-11 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 26.4 Weight (kg) 66 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 84 ALT 15 AST 21 Billirubin 9 Cholesterol 4.5 High Density Lipoprotein(HDL) 1.39 Low Density Lipoprotein (LDL) 2.4 Triglycerides 1.48 Glucose 5.3 Creatinine 81 Ferritin 229 Thyroid Stimulating Hormone (TSH) 2.36 Urea 6.9 Vitamin B12 507 White blood cells 5.9 HFD_index 0.362151678558909 CRP (mg/L) 6 CXCL11 (pg/ml) not collected CCL11 (pg/ml) not collected IL17A (pg/ml) not collected IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190783 SAMN10636319 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.007 host_residential_stratification Community treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 71 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 27 collection_date 2015-11-23 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 27 Weight (kg) 67 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 94 ALT 17 AST 22 Billirubin 11 Cholesterol 4.3 High Density Lipoprotein(HDL) 1.42 Low Density Lipoprotein (LDL) 2.2 Triglycerides 1.43 Glucose 5.3 Creatinine 85 Ferritin 259 Thyroid Stimulating Hormone (TSH) 1.93 Urea 5.7 Vitamin B12 677 White blood cells 7.1 HFD_index 0.362151678558909 CRP (mg/L) 3.1 CXCL11 (pg/ml) 5138.44749964453 CCL11 (pg/ml) 0 IL17A (pg/ml) 1.03785532276818 IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) 52.9 CD8 (%) 17.8999999999999 LPS (EU/ml) 3.98843930635838 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190784 SAMN10636322 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.007 host_residential_stratification Community treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 72 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 26.6 collection_date 2016-06-23 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 26.6 Weight (kg) 66.5 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 94 ALT 15 AST 22 Billirubin 10 Cholesterol 5 High Density Lipoprotein(HDL) 1.57 Low Density Lipoprotein (LDL) 2.9 Triglycerides 1.01 Glucose 5.4 Creatinine 85 Ferritin 243 Thyroid Stimulating Hormone (TSH) 3.44 Urea 6.1 Vitamin B12 565 White blood cells 5.2 HFD_index 0.456760924747545 CRP (mg/L) 2.2 CXCL11 (pg/ml) 697.868960042339 CCL11 (pg/ml) 0 IL17A (pg/ml) 1.1132728186168 IFN-gamma (pg/ml) 2.60801700406496 IL-10 (pg/ml) 0.129545583034851 IL-6 (pg/ml) 0.599239472485035 IL-8 (pg/ml) 19.7472906878716 TNF-alpha (pg/ml) 1.81778268877213 CD4 (%) 55.6 CD8 (%) 14.7 LPS (EU/ml) 4.81420313790255 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190785 SAMN10636321 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.007 host_residential_stratification Community treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 72 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 26.4 collection_date 2016-05-12 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 26.4 Weight (kg) 66 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 92 ALT 12 AST not collected Billirubin 8 Cholesterol not collected High Density Lipoprotein(HDL) not collected Low Density Lipoprotein (LDL) not collected Triglycerides not collected Glucose 4.9 Creatinine 79 Ferritin 301 Thyroid Stimulating Hormone (TSH) not collected Urea 7.3 Vitamin B12 590 White blood cells 6.2 HFD_index 0.411506517973558 CRP (mg/L) not collected CXCL11 (pg/ml) 261.012289518808 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.747810053051325 IFN-gamma (pg/ml) 4.23065198007021 IL-10 (pg/ml) 0.14100005880126 IL-6 (pg/ml) 0.844128490887176 IL-8 (pg/ml) 16.3848469881011 TNF-alpha (pg/ml) 1.97807689964195 CD4 (%) 63.1 CD8 (%) 16.8999999999999 LPS (EU/ml) 5.0206440957886 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190786 SAMN10636316 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.006 host_residential_stratification Community treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 72 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 33.3 collection_date 2016-02-16 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 33.3 Weight (kg) 101.5 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 125 Alkaline Phosphatase 104 ALT 39 AST 21 Billirubin 22 Cholesterol 6.5 High Density Lipoprotein(HDL) 1.51 Low Density Lipoprotein (LDL) not collected Triglycerides 1.8 Glucose 6.5 Creatinine 85 Ferritin 89 Thyroid Stimulating Hormone (TSH) 1.91 Urea 6.8 Vitamin B12 276 White blood cells 7.2 HFD_index 0.428905990830346 CRP (mg/L) not collected CXCL11 (pg/ml) 39.2562533730795 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.858422754306008 IFN-gamma (pg/ml) 2.18452505506386 IL-10 (pg/ml) 0.283215188620474 IL-6 (pg/ml) 0.0153288159234005 IL-8 (pg/ml) 19.126753615141 TNF-alpha (pg/ml) 1.47570813797643 CD4 (%) 28.3 CD8 (%) 8.61999999999999 LPS (EU/ml) 4.23616845582163 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190787 SAMN10636315 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.006 host_residential_stratification Community treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 72 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 32.3 collection_date 2015-11-23 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 32.3 Weight (kg) 99 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase not collected ALT not collected AST not collected Billirubin not collected Cholesterol not collected High Density Lipoprotein(HDL) not collected Low Density Lipoprotein (LDL) not collected Triglycerides not collected Glucose not collected Creatinine not collected Ferritin not collected Thyroid Stimulating Hormone (TSH) not collected Urea not collected Vitamin B12 not collected White blood cells not collected HFD_index 0.428905990830346 CRP (mg/L) not collected CXCL11 (pg/ml) 0 CCL11 (pg/ml) 93.0671995978655 IL17A (pg/ml) 1.96787290944833 IFN-gamma (pg/ml) 5.65915795939259 IL-10 (pg/ml) 0.0829154161762041 IL-6 (pg/ml) 0.768452620841064 IL-8 (pg/ml) 8.92872034591852 TNF-alpha (pg/ml) 1.40032214612972 CD4 (%) 25.4 CD8 (%) 5.64 LPS (EU/ml) 7.28323699421965 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190788 SAMN10636318 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.006 host_residential_stratification Community treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 73 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 34.2 collection_date 2016-06-27 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 34.2 Weight (kg) 104.6 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 125 Alkaline Phosphatase not collected ALT not collected AST not collected Billirubin not collected Cholesterol not collected High Density Lipoprotein(HDL) not collected Low Density Lipoprotein (LDL) not collected Triglycerides not collected Glucose not collected Creatinine not collected Ferritin not collected Thyroid Stimulating Hormone (TSH) not collected Urea not collected Vitamin B12 not collected White blood cells not collected HFD_index 0.240983477841378 CRP (mg/L) not collected CXCL11 (pg/ml) not collected CCL11 (pg/ml) not collected IL17A (pg/ml) not collected IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190789 SAMN10636317 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.006 host_residential_stratification Community treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 72 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 33.5 collection_date 2016-05-23 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 33.5 Weight (kg) 102.5 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 125 Alkaline Phosphatase 74 ALT 16 AST 18 Billirubin 18 Cholesterol 6.1 High Density Lipoprotein(HDL) 1.3 Low Density Lipoprotein (LDL) 3.9 Triglycerides 1.95 Glucose 6.8 Creatinine 95 Ferritin 110 Thyroid Stimulating Hormone (TSH) 0.98 Urea 8.3 Vitamin B12 227 White blood cells 8.6 HFD_index 0.240983477841378 CRP (mg/L) 5.9 CXCL11 (pg/ml) 51.3080223396891 CCL11 (pg/ml) not collected IL17A (pg/ml) not collected IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190790 SAMN10636324 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.008 host_residential_stratification Community treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 68 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 29.9 collection_date 2016-02-17 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 29.9 Weight (kg) 70 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 100 ALT 20 AST 27 Billirubin 6 Cholesterol 5.3 High Density Lipoprotein(HDL) 1.72 Low Density Lipoprotein (LDL) 2.8 Triglycerides 1.81 Glucose 4.3 Creatinine 49 Ferritin 25 Thyroid Stimulating Hormone (TSH) 2.13 Urea 3.6 Vitamin B12 487 White blood cells 10.8 HFD_index 0.389073246047253 CRP (mg/L) 6.9 CXCL11 (pg/ml) 1397.83329403577 CCL11 (pg/ml) 0 IL17A (pg/ml) 1.42594788351069 IFN-gamma (pg/ml) 73.2649149476382 IL-10 (pg/ml) 1.7353741291124 IL-6 (pg/ml) 1.30361797373115 IL-8 (pg/ml) 8.04127379291903 TNF-alpha (pg/ml) 1.74322439873425 CD4 (%) 51.3 CD8 (%) 7.16 LPS (EU/ml) 4.39503588516746 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190791 SAMN10636323 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.008 host_residential_stratification Community treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 67 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 29.9 collection_date 2015-11-25 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 29.9 Weight (kg) 70 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 98 ALT 25 AST 33 Billirubin 8 Cholesterol 6.2 High Density Lipoprotein(HDL) 2.12 Low Density Lipoprotein (LDL) 3.6 Triglycerides 1 Glucose 5.3 Creatinine 51 Ferritin 26 Thyroid Stimulating Hormone (TSH) 2.16 Urea 5.8 Vitamin B12 459 White blood cells 6.6 HFD_index 0.389073246047253 CRP (mg/L) 4.4 CXCL11 (pg/ml) 3118.52128891278 CCL11 (pg/ml) 112.721512626903 IL17A (pg/ml) 1.12969924980873 IFN-gamma (pg/ml) 27.600782750735 IL-10 (pg/ml) 0.239803124924272 IL-6 (pg/ml) 0.513257306820797 IL-8 (pg/ml) 14.0717020709262 TNF-alpha (pg/ml) 2.58617170552457 CD4 (%) 44.5 CD8 (%) 8.38 LPS (EU/ml) 19.2703349282296 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190792 SAMN10636582 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.034 host_residential_stratification YoungHealthy treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 39 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 22.6 collection_date 2016-06-16 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 22.6 Weight (kg) 74 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 100 ALT 23 AST 25 Billirubin 33 Cholesterol 6.5 High Density Lipoprotein(HDL) 1.57 Low Density Lipoprotein (LDL) 4.2 Triglycerides 1.42 Glucose 4.3 Creatinine 79 Ferritin 107 Thyroid Stimulating Hormone (TSH) 2.7 Urea 6.9 Vitamin B12 245 White blood cells 5.8 HFD_index 0.538180950813889 CRP (mg/L) 1.3 CXCL11 (pg/ml) not collected CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 0 IL-10 (pg/ml) 0 IL-6 (pg/ml) 0 IL-8 (pg/ml) 0 TNF-alpha (pg/ml) 0 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 5.6729975227085 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190793 SAMN10636367 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.021 host_residential_stratification Community treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 71 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 29.7 collection_date 2016-07-18 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 29.7 Weight (kg) 90 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 63 ALT 23 AST 25 Billirubin 9 Cholesterol 7.3 High Density Lipoprotein(HDL) 1.86 Low Density Lipoprotein (LDL) 5 Triglycerides 0.77 Glucose 6 Creatinine 64 Ferritin 85 Thyroid Stimulating Hormone (TSH) 1.36 Urea 4.6 Vitamin B12 467 White blood cells 5.7 HFD_index 0.436670175794523 CRP (mg/L) not collected CXCL11 (pg/ml) 40.1810783883876 CCL11 (pg/ml) 0 IL17A (pg/ml) 1.02724920274025 IFN-gamma (pg/ml) 7.12876661151824 IL-10 (pg/ml) 0.1674213648428 IL-6 (pg/ml) 0.284104994752506 IL-8 (pg/ml) 9.11169145937896 TNF-alpha (pg/ml) 2.05021392328794 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 16.7583732057416 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190794 SAMN10636365 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.020 host_residential_stratification Community treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 86 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 20.3 collection_date 2016-10-20 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 20.3 Weight (kg) 65 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 62 ALT 39 AST 39 Billirubin 20 Cholesterol 3.6 High Density Lipoprotein(HDL) 1.29 Low Density Lipoprotein (LDL) 1.9 Triglycerides 0.82 Glucose 6.1 Creatinine 74 Ferritin 63 Thyroid Stimulating Hormone (TSH) 0.72 Urea 8.4 Vitamin B12 230 White blood cells 4.8 HFD_index 0.466750070774846 CRP (mg/L) 0.1 CXCL11 (pg/ml) 0 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.710733122671153 IFN-gamma (pg/ml) 10.7124440811134 IL-10 (pg/ml) 0.467645970848203 IL-6 (pg/ml) 0.542932789521751 IL-8 (pg/ml) 13.9833961913497 TNF-alpha (pg/ml) 1.75948293277103 CD4 (%) 33.7 CD8 (%) 4.74 LPS (EU/ml) 1.1938202247191 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190795 SAMN10636447 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.015 host_residential_stratification LongStay treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 88 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 8 host_body_mass_index 25 collection_date 2015-11-19 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 25 Weight (kg) 66.3 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 8 Appendix C - FIM 54 Alkaline Phosphatase 82 ALT 10 AST 17 Billirubin 7 Cholesterol 4.3 High Density Lipoprotein(HDL) 1.18 Low Density Lipoprotein (LDL) 2.3 Triglycerides 1.64 Glucose 7.2 Creatinine 61 Ferritin 12 Thyroid Stimulating Hormone (TSH) 2.45 Urea 4.9 Vitamin B12 211 White blood cells 3 HFD_index 0.34142180001035 CRP (mg/L) 0.9 CXCL11 (pg/ml) not collected CCL11 (pg/ml) not collected IL17A (pg/ml) not collected IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) 57.4 CD8 (%) not collected LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190796 SAMN10636448 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.016 host_residential_stratification LongStay treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 72 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 2 host_body_mass_index 28 collection_date 2015-03-16 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 28 Weight (kg) 78.5 Appendix A - Charlson co-morbidity 3 Appendix B - Barthel Score 2 Appendix C - FIM 38 Alkaline Phosphatase 103 ALT 15 AST 16 Billirubin 8 Cholesterol 3.5 High Density Lipoprotein(HDL) 0.98 Low Density Lipoprotein (LDL) 1.8 Triglycerides 1.53 Glucose 4.4 Creatinine 183 Ferritin not collected Thyroid Stimulating Hormone (TSH) 2.37 Urea 7.2 Vitamin B12 not collected White blood cells 6.9 HFD_index not collected CRP (mg/L) 2.5 CXCL11 (pg/ml) 156.744781040995 CCL11 (pg/ml) not applicable IL17A (pg/ml) 2.22590344245721 IFN-gamma (pg/ml) 7.0964769828423 IL-10 (pg/ml) 0.48577743786197 IL-6 (pg/ml) 1.23020416641067 IL-8 (pg/ml) 13.7050756711552 TNF-alpha (pg/ml) 4.97568821672305 CD4 (%) 65.5999999999999 CD8 (%) 16.3999999999999 LPS (EU/ml) 4.0327868852459 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190797 SAMN10636445 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.015 host_residential_stratification LongStay treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 88 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 6 host_body_mass_index 26.3 collection_date 2015-07-06 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 26.3 Weight (kg) 65.66 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 6 Appendix C - FIM 59 Alkaline Phosphatase 93 ALT 6 AST 20 Billirubin 7 Cholesterol 5 High Density Lipoprotein(HDL) 1.26 Low Density Lipoprotein (LDL) 2.9 Triglycerides 1.72 Glucose 8.4 Creatinine 53 Ferritin 15 Thyroid Stimulating Hormone (TSH) 2.19 Urea 4.3 Vitamin B12 224 White blood cells 3.8 HFD_index 0.336319741018414 CRP (mg/L) 2.5 CXCL11 (pg/ml) 941.402835407688 CCL11 (pg/ml) 158.267961668678 IL17A (pg/ml) 0.928406912065757 IFN-gamma (pg/ml) 8.33634880161961 IL-10 (pg/ml) 0.509566410048652 IL-6 (pg/ml) 12.4438866435731 IL-8 (pg/ml) 9.31121013232468 TNF-alpha (pg/ml) 3.21168499546809 CD4 (%) 9.75 CD8 (%) 10.4 LPS (EU/ml) 10.2295081967213 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190798 SAMN10636446 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.015 host_residential_stratification LongStay treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 88 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 6 host_body_mass_index 26.6 collection_date 2015-09-29 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 26.6 Weight (kg) 66.4 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 6 Appendix C - FIM 59 Alkaline Phosphatase not collected ALT not collected AST not collected Billirubin not collected Cholesterol not collected High Density Lipoprotein(HDL) not collected Low Density Lipoprotein (LDL) not collected Triglycerides not collected Glucose not collected Creatinine not collected Ferritin not collected Thyroid Stimulating Hormone (TSH) not collected Urea not collected Vitamin B12 not collected White blood cells not collected HFD_index 0.336319741018414 CRP (mg/L) not collected CXCL11 (pg/ml) 515.130541309877 CCL11 (pg/ml) 805.628472887065 IL17A (pg/ml) 1.64810041389406 IFN-gamma (pg/ml) 8.64318921607601 IL-10 (pg/ml) 0.397281517405064 IL-6 (pg/ml) 5.99563476513638 IL-8 (pg/ml) 12.6295349834128 TNF-alpha (pg/ml) 3.25988171086296 CD4 (%) 16.8 CD8 (%) 14.1 LPS (EU/ml) 5.18852459016393 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190799 SAMN10636451 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.018 host_residential_stratification LongStay treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 80 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 3 host_body_mass_index 25.2 collection_date 2015-04-02 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 25.2 Weight (kg) 71 Appendix A - Charlson co-morbidity 3 Appendix B - Barthel Score 3 Appendix C - FIM 49 Alkaline Phosphatase 116 ALT 16 AST not collected Billirubin 8 Cholesterol 4.7 High Density Lipoprotein(HDL) 1.21 Low Density Lipoprotein (LDL) 2.8 Triglycerides 1.53 Glucose 5.5 Creatinine 49 Ferritin 64 Thyroid Stimulating Hormone (TSH) 1.57 Urea 6.5 Vitamin B12 591 White blood cells 10.5 HFD_index not collected CRP (mg/L) 22.8 CXCL11 (pg/ml) 1442.34131254564 CCL11 (pg/ml) 372.110348795602 IL17A (pg/ml) 2.17097786206156 IFN-gamma (pg/ml) 4.23658132915879 IL-10 (pg/ml) 0.543526304068925 IL-6 (pg/ml) 9.64028700630109 IL-8 (pg/ml) 16.9082906761222 TNF-alpha (pg/ml) 4.64599652614058 CD4 (%) 43.7 CD8 (%) 11.1 LPS (EU/ml) 7.27868852459016 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190800 SAMN10636452 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.018 host_residential_stratification LongStay treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 81 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 1 host_body_mass_index 24.4 collection_date 2015-08-05 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.4 Weight (kg) 69 Appendix A - Charlson co-morbidity 3 Appendix B - Barthel Score 1 Appendix C - FIM 37 Alkaline Phosphatase 118 ALT 17 AST 31 Billirubin 7 Cholesterol 4.3 High Density Lipoprotein(HDL) 0.99 Low Density Lipoprotein (LDL) 2.7 Triglycerides 1.28 Glucose 6.2 Creatinine 49 Ferritin 45 Thyroid Stimulating Hormone (TSH) 1.55 Urea 7.5 Vitamin B12 748 White blood cells 7.7 HFD_index 0.262408370973155 CRP (mg/L) 13.8 CXCL11 (pg/ml) 1153.31494992384 CCL11 (pg/ml) 435.523045939779 IL17A (pg/ml) 2.17097786206156 IFN-gamma (pg/ml) 8.5292603972396 IL-10 (pg/ml) 0.630852959123611 IL-6 (pg/ml) 2.24281439620019 IL-8 (pg/ml) 20.1113849324286 TNF-alpha (pg/ml) 4.78510019873514 CD4 (%) 46 CD8 (%) 18.8 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190801 SAMN10636449 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.016 host_residential_stratification LongStay treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 73 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 2 host_body_mass_index 28.7 collection_date 2015-07-30 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 28.7 Weight (kg) 81 Appendix A - Charlson co-morbidity 4 Appendix B - Barthel Score 2 Appendix C - FIM 36 Alkaline Phosphatase 99 ALT 11 AST 14 Billirubin 6 Cholesterol 3.7 High Density Lipoprotein(HDL) 1.04 Low Density Lipoprotein (LDL) 2.2 Triglycerides 1.16 Glucose 4 Creatinine 174 Ferritin 40 Thyroid Stimulating Hormone (TSH) 3.44 Urea 8 Vitamin B12 170 White blood cells 7.8 HFD_index 0.224544141012388 CRP (mg/L) 7.5 CXCL11 (pg/ml) 365.448464393731 CCL11 (pg/ml) 726.447754742285 IL17A (pg/ml) 0.983996036895978 IFN-gamma (pg/ml) 3.70684040573299 IL-10 (pg/ml) 0.460272735158202 IL-6 (pg/ml) 1.45300589360294 IL-8 (pg/ml) 10.4434282470968 TNF-alpha (pg/ml) 4.54059796683791 CD4 (%) 61.7 CD8 (%) 15.4 LPS (EU/ml) 3.86885245901639 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190802 SAMN10636450 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.016 host_residential_stratification LongStay treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 73 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 2 host_body_mass_index 27.6 collection_date 2015-10-02 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 27.6 Weight (kg) 77.8 Appendix A - Charlson co-morbidity 4 Appendix B - Barthel Score 2 Appendix C - FIM 36 Alkaline Phosphatase not collected ALT not collected AST 14 Billirubin not collected Cholesterol 3.2 High Density Lipoprotein(HDL) 1.04 Low Density Lipoprotein (LDL) 1.8 Triglycerides 0.79 Glucose 4 Creatinine not collected Ferritin 34 Thyroid Stimulating Hormone (TSH) 3.71 Urea not collected Vitamin B12 181 White blood cells 8 HFD_index 0.224544141012388 CRP (mg/L) 2.5 CXCL11 (pg/ml) 120.218167839163 CCL11 (pg/ml) 383.567602080958 IL17A (pg/ml) 3.81174123028951 IFN-gamma (pg/ml) 3.55377410259935 IL-10 (pg/ml) 0.446662907992857 IL-6 (pg/ml) 2.09701157270631 IL-8 (pg/ml) 16.0192620614197 TNF-alpha (pg/ml) 4.28377279022093 CD4 (%) 64.4 CD8 (%) 15 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190803 SAMN10636523 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.016 host_residential_stratification YoungHealthy treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 60 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 23.9 collection_date 2015-12-11 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23.9 Weight (kg) 56 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 56 ALT 16 AST 26 Billirubin 8 Cholesterol 6 High Density Lipoprotein(HDL) 1.91 Low Density Lipoprotein (LDL) 3.8 Triglycerides 0.75 Glucose 5.2 Creatinine 66 Ferritin 63 Thyroid Stimulating Hormone (TSH) 2.41 Urea 5.7 Vitamin B12 356 White blood cells 4 HFD_index 0.546396539135297 CRP (mg/L) 0.7 CXCL11 (pg/ml) 7.55453633049807 CCL11 (pg/ml) 17.4114794427988 IL17A (pg/ml) 7.98699264552573e-07 IFN-gamma (pg/ml) 29.2560735453158 IL-10 (pg/ml) 0.13842678347407 IL-6 (pg/ml) 0.396381271234062 IL-8 (pg/ml) 12.7301899762338 TNF-alpha (pg/ml) 1.35120619433964 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190804 SAMN10636524 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.016 host_residential_stratification YoungHealthy treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 60 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 24.2 collection_date 2015-02-18 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.2 Weight (kg) 56 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 63 ALT 21 AST 34 Billirubin 7 Cholesterol 6.7 High Density Lipoprotein(HDL) 2.37 Low Density Lipoprotein (LDL) 4 Triglycerides 0.64 Glucose 4.3 Creatinine 61 Ferritin 49 Thyroid Stimulating Hormone (TSH) 1.65 Urea 6.5 Vitamin B12 227 White blood cells 4.2 HFD_index 0.505783606497756 CRP (mg/L) 0.7 CXCL11 (pg/ml) not collected CCL11 (pg/ml) not collected IL17A (pg/ml) not collected IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) 56.7 CD8 (%) 16.3 LPS (EU/ml) 8.13934426229508 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190805 SAMN10636453 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.018 host_residential_stratification LongStay treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 81 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score missing host_body_mass_index missing collection_date 2015-11-02 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index not collected Weight (kg) 0 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 109 ALT 13 AST 29 Billirubin 8 Cholesterol 4.5 High Density Lipoprotein(HDL) 1.15 Low Density Lipoprotein (LDL) 2.8 Triglycerides 1.22 Glucose 5.5 Creatinine 57 Ferritin 47 Thyroid Stimulating Hormone (TSH) 1.76 Urea 6.9 Vitamin B12 853 White blood cells 7 HFD_index 0.262408370973155 CRP (mg/L) 13.2 CXCL11 (pg/ml) 1385.53431000215 CCL11 (pg/ml) 485.773065913104 IL17A (pg/ml) 1.45489046162767 IFN-gamma (pg/ml) 2.84864191391958 IL-10 (pg/ml) 0.414317995222295 IL-6 (pg/ml) 1.90533995495529 IL-8 (pg/ml) 12.0468037410342 TNF-alpha (pg/ml) 2.629627271837 CD4 (%) 42.7 CD8 (%) 24.5 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190806 SAMN10636454 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.020 host_residential_stratification LongStay treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 83 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 10 host_body_mass_index 23.2 collection_date 2015-04-08 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23.2 Weight (kg) 59.5 Appendix A - Charlson co-morbidity 2 Appendix B - Barthel Score 10 Appendix C - FIM 27 Alkaline Phosphatase 125 ALT 22 AST 17 Billirubin 4 Cholesterol 4.1 High Density Lipoprotein(HDL) 1.03 Low Density Lipoprotein (LDL) 2.5 Triglycerides 1.36 Glucose 7.7 Creatinine 69 Ferritin 180 Thyroid Stimulating Hormone (TSH) 0.88 Urea 8.4 Vitamin B12 181 White blood cells 4.1 HFD_index not collected CRP (mg/L) 60.3 CXCL11 (pg/ml) 1969.66669411212 CCL11 (pg/ml) 345.539315008927 IL17A (pg/ml) 4.165704899014 IFN-gamma (pg/ml) 20.497883951834 IL-10 (pg/ml) 8.96573626441477 IL-6 (pg/ml) 1.9461724782843 IL-8 (pg/ml) 34.5709517571762 TNF-alpha (pg/ml) 10.0684328042804 CD4 (%) 43.6 CD8 (%) 13.9 LPS (EU/ml) 6.6639344262295 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190807 SAMN10636561 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.028 host_residential_stratification YoungHealthy treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 52 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 24.3 collection_date 2016-09-20 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.3 Weight (kg) 57 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 112 ALT 34 AST 24 Billirubin 15 Cholesterol 4.3 High Density Lipoprotein(HDL) 1.53 Low Density Lipoprotein (LDL) 2.4 Triglycerides 0.77 Glucose 5.2 Creatinine 60 Ferritin 152 Thyroid Stimulating Hormone (TSH) 1.09 Urea 8 Vitamin B12 194 White blood cells 6.9 HFD_index 0.551288103760327 CRP (mg/L) 0.8 CXCL11 (pg/ml) 0.688152884497376 CCL11 (pg/ml) 0 IL17A (pg/ml) 4.48173855559814e-05 IFN-gamma (pg/ml) 2.51583109131837 IL-10 (pg/ml) 0.0959762127769941 IL-6 (pg/ml) 0.0403778489670491 IL-8 (pg/ml) 7.18748536347237 TNF-alpha (pg/ml) 1.57270170923346 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 19.2703349282296 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190808 SAMN10636354 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.017 host_residential_stratification Community treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 70 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 22.9 collection_date 2016-07-21 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 22.9 Weight (kg) 64 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 98 ALT 13 AST 19 Billirubin 15 Cholesterol 5.6 High Density Lipoprotein(HDL) 1.62 Low Density Lipoprotein (LDL) 3.6 Triglycerides 0.94 Glucose 5.7 Creatinine 60 Ferritin 33 Thyroid Stimulating Hormone (TSH) 1.86 Urea 4.2 Vitamin B12 190 White blood cells 4.8 HFD_index 0.459690718417597 CRP (mg/L) 0.8 CXCL11 (pg/ml) 1961.12568632627 CCL11 (pg/ml) 0 IL17A (pg/ml) 1.69329482026222 IFN-gamma (pg/ml) 2.60066033877585 IL-10 (pg/ml) 0.320721996322991 IL-6 (pg/ml) 0.275597292952887 IL-8 (pg/ml) 8.64940841471054 TNF-alpha (pg/ml) 1.80964412687622 CD4 (%) 38.1 CD8 (%) not collected LPS (EU/ml) 18.2834928229665 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190809 SAMN10636372 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.022 host_residential_stratification Community treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 68 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 24.8 collection_date 2016-09-21 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.8 Weight (kg) 85.8 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 68 ALT 17 AST 29 Billirubin 11 Cholesterol 6.4 High Density Lipoprotein(HDL) 1.32 Low Density Lipoprotein (LDL) 4.6 Triglycerides 1.12 Glucose 4.7 Creatinine 81 Ferritin 98 Thyroid Stimulating Hormone (TSH) 2.4 Urea 5.1 Vitamin B12 154 White blood cells 4.4 HFD_index 0.320906200445439 CRP (mg/L) 2 CXCL11 (pg/ml) 114.3623140718 CCL11 (pg/ml) 0 IL17A (pg/ml) 1.67726732099876 IFN-gamma (pg/ml) 7.50772817373037 IL-10 (pg/ml) 0.0876684820078389 IL-6 (pg/ml) 0.784156035608328 IL-8 (pg/ml) 16.9846694755454 TNF-alpha (pg/ml) 2.74138345810718 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 17.834928229665 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190810 SAMN10636345 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.013 host_residential_stratification Community treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 66 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 26.2 collection_date 2016-06-13 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 26.2 Weight (kg) 63 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 112 ALT 25 AST 28 Billirubin 12 Cholesterol 7.3 High Density Lipoprotein(HDL) 2.07 Low Density Lipoprotein (LDL) not collected Triglycerides 1.3 Glucose 5 Creatinine 66 Ferritin 93 Thyroid Stimulating Hormone (TSH) 1.4 Urea 5.9 Vitamin B12 325 White blood cells 5.1 HFD_index 0.40678934510884 CRP (mg/L) 0.8 CXCL11 (pg/ml) 1053.78966111691 CCL11 (pg/ml) 0 IL17A (pg/ml) 1.74173063633282 IFN-gamma (pg/ml) 4.01991712933824 IL-10 (pg/ml) 0.123573450201795 IL-6 (pg/ml) 0.258518997098416 IL-8 (pg/ml) 10.321504967165 TNF-alpha (pg/ml) 0.900638571710878 CD4 (%) 50.5 CD8 (%) 15.4 LPS (EU/ml) 18.1040669856459 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190811 SAMN10636346 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.013 host_residential_stratification Community treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 66 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 25.8 collection_date 2016-07-26 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 25.8 Weight (kg) 62 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 105 ALT 18 AST 27 Billirubin 10 Cholesterol 6.1 High Density Lipoprotein(HDL) 1.91 Low Density Lipoprotein (LDL) 3.6 Triglycerides 1.27 Glucose 4.9 Creatinine 65 Ferritin 88 Thyroid Stimulating Hormone (TSH) 1.09 Urea 4.2 Vitamin B12 239 White blood cells 4.2 HFD_index 0.406770229716823 CRP (mg/L) 0.7 CXCL11 (pg/ml) not collected CCL11 (pg/ml) not collected IL17A (pg/ml) not collected IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190812 SAMN10636347 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.016 host_residential_stratification Community treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 68 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 22 collection_date 2015-12-09 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 22 Weight (kg) 72.2 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 50 ALT 25 AST 29 Billirubin 12 Cholesterol 4 High Density Lipoprotein(HDL) 1.68 Low Density Lipoprotein (LDL) 1.6 Triglycerides 1.48 Glucose 4 Creatinine 81 Ferritin 120 Thyroid Stimulating Hormone (TSH) 2.3 Urea 5 Vitamin B12 421 White blood cells 5.1 HFD_index 0.557865217009352 CRP (mg/L) 0.6 CXCL11 (pg/ml) 29.6669486649584 CCL11 (pg/ml) 89.1856572976488 IL17A (pg/ml) 0.747810053051325 IFN-gamma (pg/ml) 12.8952011334538 IL-10 (pg/ml) 0.0487156772578294 IL-6 (pg/ml) 0.200902608529124 IL-8 (pg/ml) 17.0642501602537 TNF-alpha (pg/ml) 1.34386914676184 CD4 (%) 17.3999999999999 CD8 (%) 7.36 LPS (EU/ml) 11.4712918660287 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190813 SAMN10636562 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.029 host_residential_stratification YoungHealthy treatment Placebo time_point week0 host Homo sapiens isolate Stool age not applicable host_age 22 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 20.5 collection_date 2016-02-09 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 20.5 Weight (kg) 69.5 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 90 ALT 23 AST 22 Billirubin 15 Cholesterol 5.7 High Density Lipoprotein(HDL) 2.09 Low Density Lipoprotein (LDL) 3.2 Triglycerides 0.93 Glucose 4.3 Creatinine 86 Ferritin 105 Thyroid Stimulating Hormone (TSH) 1.34 Urea 3.9 Vitamin B12 186 White blood cells 5.6 HFD_index 0.351682962039078 CRP (mg/L) 0.1 CXCL11 (pg/ml) 0 CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 1.87593154925921 IL-10 (pg/ml) 0.0316162743354566 IL-6 (pg/ml) 0 IL-8 (pg/ml) 11.2369421693783 TNF-alpha (pg/ml) 1.17730061334612 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 0.140449438202247 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190814 SAMN10636560 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.028 host_residential_stratification YoungHealthy treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 52 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 23.8 collection_date 2016-08-08 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23.8 Weight (kg) 56 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 123 ALT 30 AST 26 Billirubin 11 Cholesterol 5 High Density Lipoprotein(HDL) 1.56 Low Density Lipoprotein (LDL) 3 Triglycerides 0.87 Glucose 4.6 Creatinine 63 Ferritin 127 Thyroid Stimulating Hormone (TSH) 1.26 Urea 5.7 Vitamin B12 182 White blood cells 7.8 HFD_index 0.530789201177454 CRP (mg/L) not collected CXCL11 (pg/ml) 1.08392619740841 CCL11 (pg/ml) 0 IL17A (pg/ml) 7.70847278491065e-05 IFN-gamma (pg/ml) 7.50925480993231 IL-10 (pg/ml) 0.133072396012763 IL-6 (pg/ml) 0.0598241710152246 IL-8 (pg/ml) 9.00103573455833 TNF-alpha (pg/ml) 2.13340921126743 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 19.090909090909 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190815 SAMN10636350 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.016 host_residential_stratification Community treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 69 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 22.1 collection_date 2016-07-13 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 22.1 Weight (kg) 72.5 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 52 ALT 27 AST 34 Billirubin 14 Cholesterol 3.8 High Density Lipoprotein(HDL) 1.73 Low Density Lipoprotein (LDL) 1.7 Triglycerides 0.89 Glucose 4.3 Creatinine 83 Ferritin 113 Thyroid Stimulating Hormone (TSH) 2.31 Urea 4.5 Vitamin B12 495 White blood cells 4.1 HFD_index 0.534820253855592 CRP (mg/L) 0.5 CXCL11 (pg/ml) 37.5057457113182 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.780848218753024 IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190816 SAMN10636351 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.017 host_residential_stratification Community treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 69 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 22.6 collection_date 2015-12-10 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 22.6 Weight (kg) 63 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 104 ALT 13 AST 19 Billirubin 19 Cholesterol 6.3 High Density Lipoprotein(HDL) 1.64 Low Density Lipoprotein (LDL) 4.2 Triglycerides 1.04 Glucose 5.3 Creatinine 64 Ferritin 43 Thyroid Stimulating Hormone (TSH) 2.56 Urea 4.6 Vitamin B12 240 White blood cells 4.7 HFD_index 0.500466556498713 CRP (mg/L) 1.7 CXCL11 (pg/ml) 117.900672081546 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.888242186204555 IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) 23.4 CD8 (%) 8.53999999999999 LPS (EU/ml) 17.5657894736842 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190817 SAMN10636352 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.017 host_residential_stratification Community treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 70 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 23.2 collection_date 2016-03-16 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23.2 Weight (kg) 64.7 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 117 ALT not collected AST 20 Billirubin not collected Cholesterol 5.6 High Density Lipoprotein(HDL) 1.63 Low Density Lipoprotein (LDL) 3.6 Triglycerides 0.82 Glucose 5.2 Creatinine 57 Ferritin 47 Thyroid Stimulating Hormone (TSH) 2.93 Urea 4.3 Vitamin B12 307 White blood cells 5.9 HFD_index 0.500466556498713 CRP (mg/L) 1.1 CXCL11 (pg/ml) 493.757141818247 CCL11 (pg/ml) 71.1587015451404 IL17A (pg/ml) 0.740802577739677 IFN-gamma (pg/ml) 4.50020882316461 IL-10 (pg/ml) 0.417264716049871 IL-6 (pg/ml) 0.518662672880264 IL-8 (pg/ml) 5.08894875424156 TNF-alpha (pg/ml) 1.50131446133426 CD4 (%) 33.1 CD8 (%) 42.4 LPS (EU/ml) 18.3732057416267 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190818 SAMN10636353 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.017 host_residential_stratification Community treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 70 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 23.2 collection_date 2016-06-09 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23.2 Weight (kg) 64.8 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 99 ALT 15 AST 19 Billirubin 17 Cholesterol 5.7 High Density Lipoprotein(HDL) 1.56 Low Density Lipoprotein (LDL) 3.8 Triglycerides 0.71 Glucose 5.5 Creatinine 62 Ferritin 39 Thyroid Stimulating Hormone (TSH) 2 Urea 4.4 Vitamin B12 212 White blood cells 4.5 HFD_index 0.459690718417597 CRP (mg/L) 0.8 CXCL11 (pg/ml) 2228.46553441701 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.710733122671153 IFN-gamma (pg/ml) 2.36989372972012 IL-10 (pg/ml) 0.24719241114823 IL-6 (pg/ml) 0.505140839562925 IL-8 (pg/ml) 7.37793634915778 TNF-alpha (pg/ml) 1.35058574448192 CD4 (%) 29.3 CD8 (%) 35.5 LPS (EU/ml) 18.1040669856459 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190819 SAMN10636555 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.027 host_residential_stratification YoungHealthy treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 62 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 27 collection_date 2016-05-05 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 27 Weight (kg) 69 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 39 ALT 21 AST 35 Billirubin 13 Cholesterol 4.4 High Density Lipoprotein(HDL) 1.83 Low Density Lipoprotein (LDL) 2.2 Triglycerides 0.91 Glucose 4.3 Creatinine 51 Ferritin 25 Thyroid Stimulating Hormone (TSH) 1.96 Urea 3.4 Vitamin B12 211 White blood cells 5.4 HFD_index 0.509991699106558 CRP (mg/L) 0.7 CXCL11 (pg/ml) 0 CCL11 (pg/ml) 14.8484428528825 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 2.86928349319199 IL-10 (pg/ml) 0.131128470869204 IL-6 (pg/ml) 0 IL-8 (pg/ml) 6.70771810173746 TNF-alpha (pg/ml) 1.47831273875199 CD4 (%) 60.3 CD8 (%) 12.9 LPS (EU/ml) 5.01639344262295 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190820 SAMN10636576 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.032 host_residential_stratification YoungHealthy treatment Placebo time_point week26 host Homo sapiens isolate Stool age not applicable host_age 31 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 30.5 collection_date 2016-09-08 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 30.5 Weight (kg) 95.5 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 80 ALT 37 AST 28 Billirubin 9 Cholesterol 5.6 High Density Lipoprotein(HDL) 1.16 Low Density Lipoprotein (LDL) 3.9 Triglycerides 1.08 Glucose 4.8 Creatinine 84 Ferritin 52 Thyroid Stimulating Hormone (TSH) 1.28 Urea 5.6 Vitamin B12 213 White blood cells 7.2 HFD_index 0.292976153706974 CRP (mg/L) 0.3 CXCL11 (pg/ml) not collected CCL11 (pg/ml) 52 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 0 IL-10 (pg/ml) 0 IL-6 (pg/ml) 0 IL-8 (pg/ml) 0 TNF-alpha (pg/ml) 0 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190821 SAMN10636556 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.027 host_residential_stratification YoungHealthy treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 62 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 27.7 collection_date 2016-08-02 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 27.7 Weight (kg) 71 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 41 ALT 19 AST 30 Billirubin 18 Cholesterol 4.7 High Density Lipoprotein(HDL) 1.83 Low Density Lipoprotein (LDL) 2.6 Triglycerides 0.69 Glucose 4.4 Creatinine 58 Ferritin 14 Thyroid Stimulating Hormone (TSH) 0.9 Urea 3.5 Vitamin B12 167 White blood cells 5.5 HFD_index 0.456236468499153 CRP (mg/L) 0.7 CXCL11 (pg/ml) 0 CCL11 (pg/ml) 3.51418719770866 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 2.31163955259874 IL-10 (pg/ml) 0.181672655634524 IL-6 (pg/ml) 0.144425212645468 IL-8 (pg/ml) 6.15844569748904 TNF-alpha (pg/ml) 1.51832897841972 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 18.0143540669856 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190822 SAMN10636331 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.010 host_residential_stratification Community treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 66 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 26.9 collection_date 2015-11-25 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 26.9 Weight (kg) 74 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 125 Alkaline Phosphatase 79 ALT 36 AST 33 Billirubin 14 Cholesterol 5 High Density Lipoprotein(HDL) 1.15 Low Density Lipoprotein (LDL) 3.5 Triglycerides 0.88 Glucose 5 Creatinine 98 Ferritin 205 Thyroid Stimulating Hormone (TSH) 2.87 Urea 5.9 Vitamin B12 375 White blood cells 4.7 HFD_index 0.438044191072527 CRP (mg/L) 1.3 CXCL11 (pg/ml) 0 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.771352340047046 IFN-gamma (pg/ml) 4.59296366838224 IL-10 (pg/ml) 0.166867754523424 IL-6 (pg/ml) 0.641859820997873 IL-8 (pg/ml) 12.8560173589392 TNF-alpha (pg/ml) 2.807402045827 CD4 (%) 26.7 CD8 (%) 14.4 LPS (EU/ml) 9.88439306358381 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190823 SAMN10636332 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.010 host_residential_stratification Community treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 66 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 27 collection_date 2016-02-15 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 27 Weight (kg) 74.5 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 77 ALT 35 AST 26 Billirubin 8 Cholesterol 7 High Density Lipoprotein(HDL) 1.07 Low Density Lipoprotein (LDL) 5.1 Triglycerides 1.73 Glucose 5.6 Creatinine 96 Ferritin 153 Thyroid Stimulating Hormone (TSH) 4.42 Urea 4.9 Vitamin B12 334 White blood cells 4.9 HFD_index 0.429793933245021 CRP (mg/L) 1.4 CXCL11 (pg/ml) 281.721228700676 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.766621290187808 IFN-gamma (pg/ml) 13.1582817070836 IL-10 (pg/ml) 0.409595690078943 IL-6 (pg/ml) 0.890829457641543 IL-8 (pg/ml) 9.00794455834586 TNF-alpha (pg/ml) 2.53541534579201 CD4 (%) 19.1 CD8 (%) 12.1 LPS (EU/ml) 16.3995215311004 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190824 SAMN10636329 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.009 host_residential_stratification Community treatment Placebo time_point week26 host Homo sapiens isolate Stool age not applicable host_age 78 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 25.9 collection_date 2016-05-20 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 25.9 Weight (kg) 68 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 125 Alkaline Phosphatase 61 ALT 25 AST 28 Billirubin 10 Cholesterol 3.1 High Density Lipoprotein(HDL) 0.97 Low Density Lipoprotein (LDL) not collected Triglycerides 1.26 Glucose 6.9 Creatinine 82 Ferritin 246 Thyroid Stimulating Hormone (TSH) 2.03 Urea 5.6 Vitamin B12 230 White blood cells 5 HFD_index 0.34032393127093 CRP (mg/L) 1.5 CXCL11 (pg/ml) not collected CCL11 (pg/ml) not collected IL17A (pg/ml) not collected IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) 8.76 CD8 (%) 26.3 LPS (EU/ml) 17.0275119617224 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190825 SAMN10636330 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.009 host_residential_stratification Community treatment Placebo time_point week32 host Homo sapiens isolate Stool age not applicable host_age 78 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 25.3 collection_date 2016-07-01 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 25.3 Weight (kg) 66.3 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 125 Alkaline Phosphatase 64 ALT 27 AST 30 Billirubin 12 Cholesterol 3.3 High Density Lipoprotein(HDL) 1.11 Low Density Lipoprotein (LDL) 1.6 Triglycerides 1.28 Glucose 7.5 Creatinine 79 Ferritin 232 Thyroid Stimulating Hormone (TSH) 2.36 Urea 5 Vitamin B12 218 White blood cells 4.6 HFD_index not collected CRP (mg/L) 0.8 CXCL11 (pg/ml) 188.101473961849 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.946491632715954 IFN-gamma (pg/ml) 8.85939524545291 IL-10 (pg/ml) 0.0988280630365279 IL-6 (pg/ml) 0.655132447370429 IL-8 (pg/ml) 10.8092674226621 TNF-alpha (pg/ml) 1.78116860570878 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190826 SAMN10636327 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.009 host_residential_stratification Community treatment Placebo time_point week0 host Homo sapiens isolate Stool age not applicable host_age 77 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 25.8 collection_date 2015-11-27 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 25.8 Weight (kg) 67.7 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 123 Alkaline Phosphatase 53 ALT 24 AST 25 Billirubin 7 Cholesterol 3.3 High Density Lipoprotein(HDL) 1.03 Low Density Lipoprotein (LDL) 1.7 Triglycerides 1.41 Glucose 5.9 Creatinine 78 Ferritin 161 Thyroid Stimulating Hormone (TSH) 2.3 Urea 6.2 Vitamin B12 232 White blood cells 5 HFD_index 0.34032393127093 CRP (mg/L) 0.5 CXCL11 (pg/ml) 156.630473211062 CCL11 (pg/ml) 0 IL17A (pg/ml) 1.19633223546999 IFN-gamma (pg/ml) 3.44273686783756 IL-10 (pg/ml) 0.205912271796351 IL-6 (pg/ml) 0.636544745703718 IL-8 (pg/ml) 14.5387804555415 TNF-alpha (pg/ml) 2.24525450728267 CD4 (%) 29.1 CD8 (%) 10.3 LPS (EU/ml) 12.2188995215311 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190827 SAMN10636557 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.027 host_residential_stratification YoungHealthy treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 62 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 27.9 collection_date 2016-09-26 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 27.9 Weight (kg) 71.5 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 42 ALT 16 AST 29 Billirubin 14 Cholesterol 4.4 High Density Lipoprotein(HDL) 1.79 Low Density Lipoprotein (LDL) 2.2 Triglycerides 0.83 Glucose 4.3 Creatinine 60 Ferritin 13 Thyroid Stimulating Hormone (TSH) 1.12 Urea 3.8 Vitamin B12 172 White blood cells 3.7 HFD_index 0.456236468499153 CRP (mg/L) 0.9 CXCL11 (pg/ml) 0 CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 2.8867854153637 IL-10 (pg/ml) 0.18910984083809 IL-6 (pg/ml) 0 IL-8 (pg/ml) 7.65909481113432 TNF-alpha (pg/ml) 1.52479251690581 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 18.2834928229665 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190828 SAMN10636325 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.008 host_residential_stratification Community treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 68 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 30.8 collection_date 2016-05-25 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 30.8 Weight (kg) 72 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 99 ALT 17 AST 28 Billirubin 7 Cholesterol 6.2 High Density Lipoprotein(HDL) 1.96 Low Density Lipoprotein (LDL) 3.4 Triglycerides 1.68 Glucose 5.9 Creatinine 55 Ferritin 24 Thyroid Stimulating Hormone (TSH) 2.5 Urea 5 Vitamin B12 406 White blood cells 9.9 HFD_index 0.300659113539453 CRP (mg/L) 10.3 CXCL11 (pg/ml) 60.2633467390079 CCL11 (pg/ml) 0 IL17A (pg/ml) 1.08880827364216 IFN-gamma (pg/ml) 67.3413373030967 IL-10 (pg/ml) 0.171300210144269 IL-6 (pg/ml) 1.91920776665449 IL-8 (pg/ml) 8.28006566299655 TNF-alpha (pg/ml) 2.98783284306068 CD4 (%) 37.4 CD8 (%) 7.71 LPS (EU/ml) 12.2188995215311 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190829 SAMN10636326 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.008 host_residential_stratification Community treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 68 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 30.5 collection_date 2016-07-06 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 30.5 Weight (kg) 71.5 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase not collected ALT not collected AST not collected Billirubin not collected Cholesterol not collected High Density Lipoprotein(HDL) not collected Low Density Lipoprotein (LDL) not collected Triglycerides not collected Glucose not collected Creatinine not collected Ferritin not collected Thyroid Stimulating Hormone (TSH) not collected Urea not collected Vitamin B12 not collected White blood cells not collected HFD_index 0.311412943249466 CRP (mg/L) not collected CXCL11 (pg/ml) not collected CCL11 (pg/ml) not collected IL17A (pg/ml) not collected IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190830 SAMN10636380 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.024 host_residential_stratification Community treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 69 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 27.1 collection_date 2016-10-27 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 27.1 Weight (kg) 69.5 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 73 ALT 16 AST 26 Billirubin 12 Cholesterol 4.5 High Density Lipoprotein(HDL) 1.57 Low Density Lipoprotein (LDL) 2.6 Triglycerides 0.74 Glucose 5.1 Creatinine 6.8 Ferritin 198 Thyroid Stimulating Hormone (TSH) 3.44 Urea 6.8 Vitamin B12 214 White blood cells 4 HFD_index 0.336773508757646 CRP (mg/L) 3.5 CXCL11 (pg/ml) 0 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.964503030904552 IFN-gamma (pg/ml) 10.6749179834914 IL-10 (pg/ml) 0.18520275542377 IL-6 (pg/ml) 0.875284364740056 IL-8 (pg/ml) 16.6135584209167 TNF-alpha (pg/ml) 1.50670709246607 CD4 (%) 27.7 CD8 (%) 9.25 LPS (EU/ml) 8.76961189099917 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190831 SAMN10636558 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.028 host_residential_stratification YoungHealthy treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 52 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 23.9 collection_date 2016-02-09 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23.9 Weight (kg) 56 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 133 ALT 34 AST 24 Billirubin 15 Cholesterol 4.8 High Density Lipoprotein(HDL) 1.72 Low Density Lipoprotein (LDL) 2.6 Triglycerides 1.12 Glucose 4.9 Creatinine 59 Ferritin 153 Thyroid Stimulating Hormone (TSH) 1.7 Urea 6.5 Vitamin B12 188 White blood cells 7.5 HFD_index 0.614463741215227 CRP (mg/L) 0.7 CXCL11 (pg/ml) 1388.44429753827 CCL11 (pg/ml) 112.721512626903 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 0.61425218286507 IL-10 (pg/ml) 0.177346080697638 IL-6 (pg/ml) 0 IL-8 (pg/ml) 8.69395790643426 TNF-alpha (pg/ml) 1.75152775972144 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 1.96629213483145 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190832 SAMN10636333 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.010 host_residential_stratification Community treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 67 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 27.2 collection_date 2016-05-23 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 27.2 Weight (kg) 75 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 125 Alkaline Phosphatase 83 ALT 30 AST 27 Billirubin 10 Cholesterol 7.5 High Density Lipoprotein(HDL) 1.12 Low Density Lipoprotein (LDL) 5.8 Triglycerides 1.39 Glucose 5.2 Creatinine 93 Ferritin 122 Thyroid Stimulating Hormone (TSH) 3.71 Urea 5.8 Vitamin B12 309 White blood cells 5.9 HFD_index 0.45011739815087 CRP (mg/L) 4 CXCL11 (pg/ml) 85.6250405997599 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.814436856706977 IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) 18.3 CD8 (%) 5.04 LPS (EU/ml) 17.834928229665 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190833 SAMN10636334 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.010 host_residential_stratification Community treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 67 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 27 collection_date 2016-05-27 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 27 Weight (kg) 74.3 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 125 Alkaline Phosphatase 73 ALT 32 AST 27 Billirubin 10 Cholesterol 4.7 High Density Lipoprotein(HDL) 1.04 Low Density Lipoprotein (LDL) 3 Triglycerides 1.54 Glucose 5.5 Creatinine 94 Ferritin 149 Thyroid Stimulating Hormone (TSH) 3.28 Urea 5.3 Vitamin B12 350 White blood cells 5.2 HFD_index 0.458440877559429 CRP (mg/L) 1.6 CXCL11 (pg/ml) 625.638540982458 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.865840618463046 IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) 7.08 CD8 (%) 6.88 LPS (EU/ml) 17.2966507177033 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190834 SAMN10636534 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.019 host_residential_stratification YoungHealthy treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 57 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 32 collection_date 2016-09-01 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 32 Weight (kg) 82 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 100 ALT 31 AST 23 Billirubin 8 Cholesterol 4.7 High Density Lipoprotein(HDL) 1.17 Low Density Lipoprotein (LDL) 2.8 Triglycerides 1.59 Glucose 6.5 Creatinine 61 Ferritin 30 Thyroid Stimulating Hormone (TSH) 1.69 Urea 5.8 Vitamin B12 156 White blood cells 5 HFD_index 0.455821702798811 CRP (mg/L) 2.4 CXCL11 (pg/ml) 282.873505748346 CCL11 (pg/ml) 1.92592658002846 IL17A (pg/ml) 4.34427094574775e-06 IFN-gamma (pg/ml) 6.75119964241958 IL-10 (pg/ml) 0.138914160489769 IL-6 (pg/ml) 0.459420001846169 IL-8 (pg/ml) 20.8494447733977 TNF-alpha (pg/ml) 2.31825113154223 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 8.38524590163934 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190835 SAMN10636366 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.021 host_residential_stratification Community treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 71 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 29.7 collection_date 2016-04-05 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 29.7 Weight (kg) 90 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 73 ALT 21 AST 22 Billirubin 7 Cholesterol 8 High Density Lipoprotein(HDL) 1.67 Low Density Lipoprotein (LDL) 5.6 Triglycerides 1.61 Glucose 5.4 Creatinine 68 Ferritin 104 Thyroid Stimulating Hormone (TSH) 1.57 Urea 3.9 Vitamin B12 725 White blood cells 7.3 HFD_index 0.383514453887286 CRP (mg/L) 0.6 CXCL11 (pg/ml) 94.0010716349814 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.747810053051325 IFN-gamma (pg/ml) 5.51745508666525 IL-10 (pg/ml) 0.111152432153751 IL-6 (pg/ml) 0.278435458296527 IL-8 (pg/ml) 8.03548254869942 TNF-alpha (pg/ml) 1.70936840423877 CD4 (%) 27.5 CD8 (%) 26.7 LPS (EU/ml) 19.090909090909 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190836 SAMN10636533 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.019 host_residential_stratification YoungHealthy treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 57 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 32.2 collection_date 2016-07-26 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 32.2 Weight (kg) 82.4 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 107 ALT 33 AST 26 Billirubin 7 Cholesterol 4.7 High Density Lipoprotein(HDL) 1.27 Low Density Lipoprotein (LDL) not collected Triglycerides 1.5 Glucose 4.4 Creatinine 58 Ferritin 36 Thyroid Stimulating Hormone (TSH) 1.82 Urea 4.6 Vitamin B12 165 White blood cells 5.3 HFD_index 0.472694997682401 CRP (mg/L) 2.29999999999999 CXCL11 (pg/ml) 337.487512634382 CCL11 (pg/ml) 2.07148300027915 IL17A (pg/ml) 1.08101351691545e-05 IFN-gamma (pg/ml) 4.09479252709312 IL-10 (pg/ml) 0.0988401143639779 IL-6 (pg/ml) 0.562805655637503 IL-8 (pg/ml) 16.2077160865649 TNF-alpha (pg/ml) 1.76829553876899 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190837 SAMN10636532 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.019 host_residential_stratification YoungHealthy treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 57 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 32 collection_date 2016-04-28 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 32 Weight (kg) 82 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 102 ALT 31 AST 20 Billirubin 6 Cholesterol 6.8 High Density Lipoprotein(HDL) 1.13 Low Density Lipoprotein (LDL) 4.6 Triglycerides 2.31 Glucose 4.4 Creatinine 57 Ferritin 48 Thyroid Stimulating Hormone (TSH) not collected Urea 4.8 Vitamin B12 182 White blood cells not collected HFD_index 0.430303480546879 CRP (mg/L) 2.29999999999999 CXCL11 (pg/ml) 408.519519773508 CCL11 (pg/ml) 4.58358910827632 IL17A (pg/ml) 3.85933548410391e-06 IFN-gamma (pg/ml) 4.07260367495164 IL-10 (pg/ml) 0.124822577501197 IL-6 (pg/ml) 0.370188193067056 IL-8 (pg/ml) 16.5652030678125 TNF-alpha (pg/ml) 1.86160112087446 CD4 (%) 52.3 CD8 (%) 18.3 LPS (EU/ml) 4.93442622950819 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190838 SAMN10636531 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.019 host_residential_stratification YoungHealthy treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 56 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 31.3 collection_date 2016-01-26 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 31.3 Weight (kg) 79.5 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 111 ALT 26 AST 22 Billirubin 7 Cholesterol 5 High Density Lipoprotein(HDL) 1.26 Low Density Lipoprotein (LDL) 2.8 Triglycerides 2.03 Glucose 4.7 Creatinine 68 Ferritin 38 Thyroid Stimulating Hormone (TSH) 2.7 Urea 6.4 Vitamin B12 150 White blood cells 5.8 HFD_index 0.430303480546879 CRP (mg/L) 2.5 CXCL11 (pg/ml) 994.731920845164 CCL11 (pg/ml) 5.35586363300096 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 8.640704529739 IL-10 (pg/ml) 0.276519868215683 IL-6 (pg/ml) 0.10339904807479 IL-8 (pg/ml) 7.88211873023414 TNF-alpha (pg/ml) 1.19989672743854 CD4 (%) 39.2999999999999 CD8 (%) 20.2 LPS (EU/ml) 5.0655737704918 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190839 SAMN10636530 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.018 host_residential_stratification YoungHealthy treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 26 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 21.3 collection_date 2016-09-01 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 21.3 Weight (kg) 56 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 75 ALT 17 AST 20 Billirubin 16 Cholesterol 5.3 High Density Lipoprotein(HDL) 1.47 Low Density Lipoprotein (LDL) 3.3 Triglycerides 1.08 Glucose 2.7 Creatinine 66 Ferritin 17 Thyroid Stimulating Hormone (TSH) 0.66 Urea 4.7 Vitamin B12 123 White blood cells 4.9 HFD_index 0.691615903027284 CRP (mg/L) 0.6 CXCL11 (pg/ml) 529.990702282329 CCL11 (pg/ml) 8.68626289190419 IL17A (pg/ml) 9.28065549269244e-06 IFN-gamma (pg/ml) 14.0749146964191 IL-10 (pg/ml) 0.453961549738496 IL-6 (pg/ml) 0.228344833562822 IL-8 (pg/ml) 10.0712692946389 TNF-alpha (pg/ml) 2.12673930146327 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190840 SAMN10636529 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.018 host_residential_stratification YoungHealthy treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 25 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 20.8 collection_date 2016-07-20 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 20.8 Weight (kg) 54.5 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 77 ALT 16 AST 22 Billirubin 12 Cholesterol 5.2 High Density Lipoprotein(HDL) 1.33 Low Density Lipoprotein (LDL) 3.5 Triglycerides 0.94 Glucose 4.1 Creatinine 68 Ferritin 16 Thyroid Stimulating Hormone (TSH) 0.75 Urea 3.7 Vitamin B12 98 White blood cells 4 HFD_index 0.650621401639543 CRP (mg/L) 4 CXCL11 (pg/ml) 451.458320715797 CCL11 (pg/ml) 3.34070283149753 IL17A (pg/ml) 3.13054894649788e-05 IFN-gamma (pg/ml) 6.08226875685106 IL-10 (pg/ml) 0.322425719431735 IL-6 (pg/ml) 0 IL-8 (pg/ml) 8.50237719353203 TNF-alpha (pg/ml) 1.41912050865542 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 4.31967213114754 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190841 SAMN10636528 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.018 host_residential_stratification YoungHealthy treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 25 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 20.7 collection_date 2016-04-21 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 20.7 Weight (kg) 54.4 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 65 ALT 14 AST 20 Billirubin 16 Cholesterol 5.8 High Density Lipoprotein(HDL) 1.84 Low Density Lipoprotein (LDL) 3.2 Triglycerides 1.77 Glucose 4.3 Creatinine 77 Ferritin 14 Thyroid Stimulating Hormone (TSH) 2.34 Urea 4.3 Vitamin B12 115 White blood cells 6.4 HFD_index 0.705574784131499 CRP (mg/L) 2.7 CXCL11 (pg/ml) 579.197917023382 CCL11 (pg/ml) 5.14171631131463 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 10.2477517943445 IL-10 (pg/ml) 0.246161249728249 IL-6 (pg/ml) 0.0856409162169285 IL-8 (pg/ml) 6.12529032406982 TNF-alpha (pg/ml) 1.65328687003697 CD4 (%) 45 CD8 (%) 25 LPS (EU/ml) 3.45901639344262 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190842 SAMN10636527 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.018 host_residential_stratification YoungHealthy treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 25 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 21 collection_date 2016-01-21 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 21 Weight (kg) 55 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 64 ALT 14 AST 20 Billirubin 10 Cholesterol 5.8 High Density Lipoprotein(HDL) 1.82 Low Density Lipoprotein (LDL) 3.3 Triglycerides 1.56 Glucose 4.9 Creatinine 75 Ferritin 29 Thyroid Stimulating Hormone (TSH) 3.52 Urea 4 Vitamin B12 147 White blood cells 5.4 HFD_index 0.680866929697868 CRP (mg/L) 2.6 CXCL11 (pg/ml) not collected CCL11 (pg/ml) not collected IL17A (pg/ml) not collected IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 7.55737704918032 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190843 SAMN10636526 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.016 host_residential_stratification YoungHealthy treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 61 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 23.9 collection_date 2016-07-08 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23.9 Weight (kg) 56 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 58 ALT 16 AST 27 Billirubin 9 Cholesterol 5.7 High Density Lipoprotein(HDL) 2.04 Low Density Lipoprotein (LDL) 3.4 Triglycerides 0.58 Glucose 5.3 Creatinine 63 Ferritin 50 Thyroid Stimulating Hormone (TSH) 1.32 Urea 7.3 Vitamin B12 316 White blood cells 3.6 HFD_index 0.532410041913591 CRP (mg/L) 0.6 CXCL11 (pg/ml) 5.89100074037753 CCL11 (pg/ml) 16.6060465573142 IL17A (pg/ml) 1.42259133436741e-05 IFN-gamma (pg/ml) 37.8843651051917 IL-10 (pg/ml) 0.115640265926454 IL-6 (pg/ml) 0.316976244017127 IL-8 (pg/ml) 15.5739892928082 TNF-alpha (pg/ml) 1.51186800935257 CD4 (%) 51.9 CD8 (%) 13.9 LPS (EU/ml) 8.13934426229508 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190844 SAMN10636525 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.016 host_residential_stratification YoungHealthy treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 60 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 23.9 collection_date 2016-05-26 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23.9 Weight (kg) 56 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 69 ALT 26 AST 34 Billirubin 2.56 Cholesterol 6 High Density Lipoprotein(HDL) 2.1 Low Density Lipoprotein (LDL) 3.5 Triglycerides 0.95 Glucose 4.2 Creatinine 67 Ferritin 56 Thyroid Stimulating Hormone (TSH) not collected Urea 6.8 Vitamin B12 297 White blood cells 6.3 HFD_index 0.532410041913591 CRP (mg/L) 0.4 CXCL11 (pg/ml) 164.969457523088 CCL11 (pg/ml) 10.163039019239 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 2.46363130531534 IL-10 (pg/ml) 0.143793437455599 IL-6 (pg/ml) 0.170845026661147 IL-8 (pg/ml) 5.33037647221012 TNF-alpha (pg/ml) 0.823090625063388 CD4 (%) 59.2 CD8 (%) 14.3 LPS (EU/ml) 6.90983606557376 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190845 SAMN10636436 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.011 host_residential_stratification LongStay treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 93 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 2 host_body_mass_index missing collection_date 2015-08-21 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index not collected Weight (kg) not collected Appendix A - Charlson co-morbidity 1 Appendix B - Barthel Score 2 Appendix C - FIM 32 Alkaline Phosphatase not collected ALT not collected AST not collected Billirubin not collected Cholesterol not collected High Density Lipoprotein(HDL) not collected Low Density Lipoprotein (LDL) not collected Triglycerides not collected Glucose not collected Creatinine not collected Ferritin not collected Thyroid Stimulating Hormone (TSH) not collected Urea not collected Vitamin B12 not collected White blood cells not collected HFD_index 0.380233409585161 CRP (mg/L) not collected CXCL11 (pg/ml) not collected CCL11 (pg/ml) not collected IL17A (pg/ml) not collected IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190846 SAMN10636435 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.011 host_residential_stratification LongStay treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 93 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 4 host_body_mass_index 30.4 collection_date 2015-05-27 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 30.4 Weight (kg) 73.9 Appendix A - Charlson co-morbidity 1 Appendix B - Barthel Score 4 Appendix C - FIM 35 Alkaline Phosphatase 148 ALT 14 AST 23 Billirubin 8 Cholesterol 6.4 High Density Lipoprotein(HDL) 1.16 Low Density Lipoprotein (LDL) 4.1 Triglycerides 2.36 Glucose 6.1 Creatinine 106 Ferritin 61 Thyroid Stimulating Hormone (TSH) 1.64 Urea 9 Vitamin B12 227 White blood cells 7 HFD_index 0.397723392549965 CRP (mg/L) 28.4 CXCL11 (pg/ml) 1113.33294156102 CCL11 (pg/ml) 269.547237953754 IL17A (pg/ml) 2.71940787368875 IFN-gamma (pg/ml) 12.8819296071458 IL-10 (pg/ml) 0.221160512491896 IL-6 (pg/ml) 3.50219751714204 IL-8 (pg/ml) 17.154686459221 TNF-alpha (pg/ml) 2.60942648304859 CD4 (%) 39 CD8 (%) 26.2 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190847 SAMN10636438 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.013 host_residential_stratification LongStay treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 90 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 14 host_body_mass_index 24.1 collection_date 2015-05-29 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.1 Weight (kg) 57.9 Appendix A - Charlson co-morbidity 1 Appendix B - Barthel Score 14 Appendix C - FIM 91 Alkaline Phosphatase 77 ALT 10 AST 15 Billirubin 11 Cholesterol 4.1 High Density Lipoprotein(HDL) 1.35 Low Density Lipoprotein (LDL) 2.4 Triglycerides 0.79 Glucose 5.7 Creatinine 63 Ferritin 43 Thyroid Stimulating Hormone (TSH) 0.59 Urea 5.1 Vitamin B12 247 White blood cells 7.2 HFD_index 0.247041704457836 CRP (mg/L) 2.5 CXCL11 (pg/ml) 1339.91490298074 CCL11 (pg/ml) 431.73890961627 IL17A (pg/ml) 2.55506271199871 IFN-gamma (pg/ml) 1.68769288807996 IL-10 (pg/ml) 0.229743503570205 IL-6 (pg/ml) 1.37852422299858 IL-8 (pg/ml) 7.82762434950558 TNF-alpha (pg/ml) 2.05408735995357 CD4 (%) 52.5 CD8 (%) 7.26 LPS (EU/ml) 5.0655737704918 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190848 SAMN10636437 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.013 host_residential_stratification LongStay treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 90 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 15 host_body_mass_index 24 collection_date 2015-02-18 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24 Weight (kg) 57.7 Appendix A - Charlson co-morbidity 1 Appendix B - Barthel Score 15 Appendix C - FIM 92 Alkaline Phosphatase 81 ALT 8 AST 17 Billirubin 10 Cholesterol 4.4 High Density Lipoprotein(HDL) 1.41 Low Density Lipoprotein (LDL) 2.6 Triglycerides 0.9 Glucose 5.2 Creatinine 65 Ferritin 30 Thyroid Stimulating Hormone (TSH) 0.57 Urea 5.9 Vitamin B12 172 White blood cells 7.7 HFD_index not collected CRP (mg/L) 2.5 CXCL11 (pg/ml) 1728.09832379539 CCL11 (pg/ml) 238.664969784206 IL17A (pg/ml) 1.73080237017165 IFN-gamma (pg/ml) 3.35537838719913 IL-10 (pg/ml) 0.271742954670958 IL-6 (pg/ml) 0.985970713531429 IL-8 (pg/ml) 15.2284511660527 TNF-alpha (pg/ml) 2.72047770273431 CD4 (%) 58.2 CD8 (%) 7.28 LPS (EU/ml) 3.83606557377049 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190849 SAMN10636440 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.014 host_residential_stratification LongStay treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 76 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 0 host_body_mass_index 34 collection_date 2015-02-16 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 34 Weight (kg) 95.1 Appendix A - Charlson co-morbidity 1 Appendix B - Barthel Score 0 Appendix C - FIM 40 Alkaline Phosphatase 66 ALT 7 AST 17 Billirubin 7 Cholesterol 6.9 High Density Lipoprotein(HDL) 1.11 Low Density Lipoprotein (LDL) 4.7 Triglycerides 2.43 Glucose 7.2 Creatinine 67 Ferritin 151 Thyroid Stimulating Hormone (TSH) 1.34 Urea 5.7 Vitamin B12 286 White blood cells 6.1 HFD_index not collected CRP (mg/L) 7 CXCL11 (pg/ml) 575.207166991748 CCL11 (pg/ml) 452.338440310349 IL17A (pg/ml) 0.621711047278482 IFN-gamma (pg/ml) 5.67225420680983 IL-10 (pg/ml) 0.495974487727799 IL-6 (pg/ml) 1.30561764483225 IL-8 (pg/ml) 10.4317732030066 TNF-alpha (pg/ml) 2.23488330767483 CD4 (%) 46.3 CD8 (%) 10.1999999999999 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190850 SAMN10636439 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.013 host_residential_stratification LongStay treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 90 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 14 host_body_mass_index 23 collection_date 2015-09-09 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23 Weight (kg) 54.55 Appendix A - Charlson co-morbidity 1 Appendix B - Barthel Score 14 Appendix C - FIM 86 Alkaline Phosphatase 81 ALT 7 AST 16 Billirubin 9 Cholesterol 4.4 High Density Lipoprotein(HDL) 1.55 Low Density Lipoprotein (LDL) 2.5 Triglycerides 0.95 Glucose 6.6 Creatinine 68 Ferritin 34 Thyroid Stimulating Hormone (TSH) 1.75 Urea 6.6 Vitamin B12 173 White blood cells 7.9 HFD_index 0.247041704457836 CRP (mg/L) 2.5 CXCL11 (pg/ml) 1094.55587606787 CCL11 (pg/ml) 303.506991374592 IL17A (pg/ml) 4.3017272381391 IFN-gamma (pg/ml) 2.86678582856665 IL-10 (pg/ml) 0.294848786962476 IL-6 (pg/ml) 1.08398503535023 IL-8 (pg/ml) 13.9331679017785 TNF-alpha (pg/ml) 2.39097184627972 CD4 (%) 52.8 CD8 (%) 7.86 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190851 SAMN10636441 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.014 host_residential_stratification LongStay treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 76 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 0 host_body_mass_index 34.5 collection_date 2015-06-16 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 34.5 Weight (kg) 97.5 Appendix A - Charlson co-morbidity 1 Appendix B - Barthel Score 0 Appendix C - FIM 27 Alkaline Phosphatase 80 ALT 9 AST 24 Billirubin 6 Cholesterol 6.7 High Density Lipoprotein(HDL) 1.01 Low Density Lipoprotein (LDL) 4.3 Triglycerides 3.16 Glucose 5.9 Creatinine 66 Ferritin 159 Thyroid Stimulating Hormone (TSH) 1.64 Urea 5.1 Vitamin B12 363 White blood cells 7.6 HFD_index 0.303931271762343 CRP (mg/L) 19.7 CXCL11 (pg/ml) 611.553821507552 CCL11 (pg/ml) 180.689070643013 IL17A (pg/ml) 2.22590344245721 IFN-gamma (pg/ml) 6.87596230162071 IL-10 (pg/ml) 0.560496034277753 IL-6 (pg/ml) 1.1994838463187 IL-8 (pg/ml) 9.86566757265648 TNF-alpha (pg/ml) 2.5548624321362 CD4 (%) 47.1 CD8 (%) 11.2 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190852 SAMN10636442 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.014 host_residential_stratification LongStay treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 77 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 0 host_body_mass_index 34 collection_date 2015-08-21 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 34 Weight (kg) 96.1 Appendix A - Charlson co-morbidity 1 Appendix B - Barthel Score 0 Appendix C - FIM 26 Alkaline Phosphatase 71 ALT 6 AST 21 Billirubin 5 Cholesterol 6.6 High Density Lipoprotein(HDL) 1.04 Low Density Lipoprotein (LDL) 3.9 Triglycerides 3.68 Glucose not collected Creatinine 65 Ferritin 151 Thyroid Stimulating Hormone (TSH) 1.47 Urea 3.9 Vitamin B12 391 White blood cells 5.3 HFD_index 0.303931271762343 CRP (mg/L) 6.6 CXCL11 (pg/ml) 494.641376564187 CCL11 (pg/ml) 105.302582130036 IL17A (pg/ml) 0.761338009669987 IFN-gamma (pg/ml) 5.58344783252663 IL-10 (pg/ml) 0.493425477885523 IL-6 (pg/ml) 0.882598685600514 IL-8 (pg/ml) 12.1483658944359 TNF-alpha (pg/ml) 2.33221969315736 CD4 (%) 50 CD8 (%) 11.9 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190853 SAMN10636444 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.015 host_residential_stratification LongStay treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 88 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 8 host_body_mass_index 26 collection_date 2015-02-23 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 26 Weight (kg) 158 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 8 Appendix C - FIM 76 Alkaline Phosphatase 78 ALT 5 AST not collected Billirubin 7 Cholesterol not collected High Density Lipoprotein(HDL) not collected Low Density Lipoprotein (LDL) not collected Triglycerides not collected Glucose 5.1 Creatinine 6 Ferritin 17 Thyroid Stimulating Hormone (TSH) 2.33 Urea 5 Vitamin B12 171 White blood cells 4.2 HFD_index not collected CRP (mg/L) 60 CXCL11 (pg/ml) 847.274839201523 CCL11 (pg/ml) 66.6253193970198 IL17A (pg/ml) 1.59293268020117 IFN-gamma (pg/ml) 7.16699599325719 IL-10 (pg/ml) 0.506168867137334 IL-6 (pg/ml) 13.1914339268101 IL-8 (pg/ml) 6.74528310473141 TNF-alpha (pg/ml) 2.69020378090471 CD4 (%) 10.4 CD8 (%) 17.5 LPS (EU/ml) 6.41803278688524 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190854 SAMN10636443 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.014 host_residential_stratification LongStay treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 76 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 0 host_body_mass_index 34 collection_date 2015-10-07 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 34 Weight (kg) 95.5 Appendix A - Charlson co-morbidity 1 Appendix B - Barthel Score 0 Appendix C - FIM 26 Alkaline Phosphatase not collected ALT not collected AST not collected Billirubin not collected Cholesterol not collected High Density Lipoprotein(HDL) not collected Low Density Lipoprotein (LDL) not collected Triglycerides not collected Glucose not collected Creatinine not collected Ferritin not collected Thyroid Stimulating Hormone (TSH) not collected Urea not collected Vitamin B12 not collected White blood cells not collected HFD_index 0.303931271762343 CRP (mg/L) not collected CXCL11 (pg/ml) not collected CCL11 (pg/ml) not collected IL17A (pg/ml) not collected IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190855 SAMN10636371 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.022 host_residential_stratification Community treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 68 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 24.7 collection_date 2016-06-21 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.7 Weight (kg) 85.4 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 60 ALT 15 AST 25 Billirubin 10 Cholesterol 6.2 High Density Lipoprotein(HDL) 1.38 Low Density Lipoprotein (LDL) 4.4 Triglycerides 0.97 Glucose 5.1 Creatinine 83 Ferritin 111 Thyroid Stimulating Hormone (TSH) 3.23 Urea 5.8 Vitamin B12 192 White blood cells 4.3 HFD_index 0.426915352964922 CRP (mg/L) 0.8 CXCL11 (pg/ml) 111.512019731227 CCL11 (pg/ml) 0 IL17A (pg/ml) 1.12421342119531 IFN-gamma (pg/ml) 4.65876594410122 IL-10 (pg/ml) 0.0724225652082618 IL-6 (pg/ml) 0.542932789521751 IL-8 (pg/ml) 11.9195632778631 TNF-alpha (pg/ml) 1.58497004347441 CD4 (%) 23.1 CD8 (%) 7.39 LPS (EU/ml) 17.6555023923444 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190856 SAMN10636515 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.014 host_residential_stratification YoungHealthy treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 26 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 22.9 collection_date 2015-11-13 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 22.9 Weight (kg) 63 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 43 ALT 22 AST 32 Billirubin 12 Cholesterol 3.6 High Density Lipoprotein(HDL) 1.15 Low Density Lipoprotein (LDL) 2.3 Triglycerides 0.46 Glucose 4.5 Creatinine 64 Ferritin 61 Thyroid Stimulating Hormone (TSH) 0.65 Urea 4.1 Vitamin B12 183 White blood cells 5.6 HFD_index 0.403155639851461 CRP (mg/L) 0.3 CXCL11 (pg/ml) 110.938187155176 CCL11 (pg/ml) 16.690223651692 IL17A (pg/ml) 6.18276718125302e-09 IFN-gamma (pg/ml) 7.57295098080554 IL-10 (pg/ml) 0.282616106380126 IL-6 (pg/ml) 0.29594574094503 IL-8 (pg/ml) 15.7320752446074 TNF-alpha (pg/ml) 1.44225574354715 CD4 (%) 47.7 CD8 (%) 19.2 LPS (EU/ml) 4.57377049180327 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190857 SAMN10636568 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.030 host_residential_stratification YoungHealthy treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 32 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 22.3 collection_date 2016-08-10 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 22.3 Weight (kg) 74.6 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 86 ALT 27 AST 25 Billirubin 30 Cholesterol 5 High Density Lipoprotein(HDL) 1.45 Low Density Lipoprotein (LDL) 3 Triglycerides 1.21 Glucose 5.3 Creatinine 82 Ferritin 138 Thyroid Stimulating Hormone (TSH) 0.81 Urea 4.7 Vitamin B12 113 White blood cells 6.9 HFD_index 0.323154506888657 CRP (mg/L) 0.6 CXCL11 (pg/ml) 46.3058054310017 CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 1.89258655358564 IL-10 (pg/ml) 0.26232652405994 IL-6 (pg/ml) 0.0598241710152246 IL-8 (pg/ml) 5.24828030825118 TNF-alpha (pg/ml) 1.74471257839606 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 11.2021531100478 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190858 SAMN10636516 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.014 host_residential_stratification YoungHealthy treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 26 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 23.8 collection_date 2016-02-18 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23.8 Weight (kg) 66 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 46 ALT 25 AST 37 Billirubin 10 Cholesterol 4.2 High Density Lipoprotein(HDL) 1.33 Low Density Lipoprotein (LDL) 2.4 Triglycerides 1.03 Glucose 4.2 Creatinine 60 Ferritin 52 Thyroid Stimulating Hormone (TSH) 1.27 Urea 3.4 Vitamin B12 132 White blood cells 4.8 HFD_index 0.426533010585807 CRP (mg/L) 0.1 CXCL11 (pg/ml) 169.546425164431 CCL11 (pg/ml) 7.45898136170743 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 4.56184754224517 IL-10 (pg/ml) 0.174253436908213 IL-6 (pg/ml) 0.052172900046586 IL-8 (pg/ml) 7.05211792315915 TNF-alpha (pg/ml) 1.03288456171419 CD4 (%) 32.5 CD8 (%) 16.3999999999999 LPS (EU/ml) 5.68032786885246 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190859 SAMN10636517 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.014 host_residential_stratification YoungHealthy treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 27 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 23.2 collection_date 2016-05-26 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23.2 Weight (kg) 62 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 45 ALT 19 AST 27 Billirubin 12 Cholesterol 3.7 High Density Lipoprotein(HDL) 1.19 Low Density Lipoprotein (LDL) 2.3 Triglycerides 0.53 Glucose 4.3 Creatinine 60 Ferritin 75 Thyroid Stimulating Hormone (TSH) 1.09 Urea 3.6 Vitamin B12 149 White blood cells 4.5 HFD_index 0.36229423501778 CRP (mg/L) 0.3 CXCL11 (pg/ml) 6.87106436254952 CCL11 (pg/ml) 9.05794013378688 IL17A (pg/ml) 1.80005224996282e-07 IFN-gamma (pg/ml) 27.2996967900459 IL-10 (pg/ml) 0.135991425058011 IL-6 (pg/ml) 0.271646643809938 IL-8 (pg/ml) 7.7330150790756 TNF-alpha (pg/ml) 1.20369031251713 CD4 (%) 41.2 CD8 (%) 16.7 LPS (EU/ml) 13.7950819672131 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190860 SAMN10636548 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.025 host_residential_stratification YoungHealthy treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 53 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 30 collection_date 2016-07-26 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 30 Weight (kg) 74 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 80 ALT 34 AST 28 Billirubin 12 Cholesterol 6 High Density Lipoprotein(HDL) 1.13 Low Density Lipoprotein (LDL) not collected Triglycerides 2.39 Glucose 5.4 Creatinine 65 Ferritin 141 Thyroid Stimulating Hormone (TSH) 0.71 Urea 6.3 Vitamin B12 136 White blood cells 3.8 HFD_index 0.512290147307731 CRP (mg/L) 2 CXCL11 (pg/ml) 0.22982516745223 CCL11 (pg/ml) 1.86419083975468 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 3.2113196370892 IL-10 (pg/ml) 0.124822577501197 IL-6 (pg/ml) 0.247034109610308 IL-8 (pg/ml) 10.5129544598263 TNF-alpha (pg/ml) 1.68849652308997 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 6.90983606557377 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190861 SAMN10636543 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.023 host_residential_stratification YoungHealthy treatment Placebo time_point week0 host Homo sapiens isolate Stool age not applicable host_age 26 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 28.1 collection_date 2016-02-02 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 28.1 Weight (kg) 91 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 72 ALT 28 AST 34 Billirubin 21 Cholesterol 5.1 High Density Lipoprotein(HDL) 1.08 Low Density Lipoprotein (LDL) 3.6 Triglycerides 0.87 Glucose 3.9 Creatinine 97 Ferritin 193 Thyroid Stimulating Hormone (TSH) 1.98 Urea 7.7 Vitamin B12 377 White blood cells 4.4 HFD_index 0.589031477177463 CRP (mg/L) 0.9 CXCL11 (pg/ml) 3.97936847625001 CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 1.67861913439175 IL-10 (pg/ml) 0.0705702706587772 IL-6 (pg/ml) 0.170996947246172 IL-8 (pg/ml) 19.9881361972524 TNF-alpha (pg/ml) 1.74904825893804 CD4 (%) 34.5 CD8 (%) 19 LPS (EU/ml) 0.147471910112359 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190862 SAMN10636518 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.014 host_residential_stratification YoungHealthy treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 27 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 21 collection_date 2016-07-07 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 21 Weight (kg) 60 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 47 ALT 37 AST 36 Billirubin 10 Cholesterol 4.5 High Density Lipoprotein(HDL) 1.28 Low Density Lipoprotein (LDL) 2.8 Triglycerides 0.9 Glucose 4.1 Creatinine 55 Ferritin 85 Thyroid Stimulating Hormone (TSH) 1.06 Urea 2.7 Vitamin B12 157 White blood cells 6.1 HFD_index 0.36229423501778 CRP (mg/L) not collected CXCL11 (pg/ml) 265.461191079317 CCL11 (pg/ml) 7.16921793856131 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 3.82885456799085 IL-10 (pg/ml) 0.178702775791001 IL-6 (pg/ml) 0.0820288295982753 IL-8 (pg/ml) 6.72616170051788 TNF-alpha (pg/ml) 0.888014865767598 CD4 (%) 52.5 CD8 (%) 18.6 LPS (EU/ml) 11.9508196721311 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190863 SAMN10636473 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.029 host_residential_stratification LongStay treatment Placebo time_point week0 host Homo sapiens isolate Stool age not applicable host_age 95 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 3 host_body_mass_index 24.09 collection_date 2015-04-28 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.09 Weight (kg) 59.4 Appendix A - Charlson co-morbidity 2 Appendix B - Barthel Score 3 Appendix C - FIM 43 Alkaline Phosphatase 53 ALT 12 AST 15 Billirubin 9 Cholesterol not collected High Density Lipoprotein(HDL) not collected Low Density Lipoprotein (LDL) not collected Triglycerides not collected Glucose not collected Creatinine 76 Ferritin not collected Thyroid Stimulating Hormone (TSH) not collected Urea 11.6 Vitamin B12 not collected White blood cells 7.91 HFD_index not collected CRP (mg/L) 92 CXCL11 (pg/ml) 546.798677218726 CCL11 (pg/ml) 219.663958566308 IL17A (pg/ml) 0.844932112477592 IFN-gamma (pg/ml) 28.2446801921473 IL-10 (pg/ml) 0.216008657039695 IL-6 (pg/ml) 3.05349707738378 IL-8 (pg/ml) 13.6501336298702 TNF-alpha (pg/ml) 4.58634526014919 CD4 (%) 56.3 CD8 (%) 27.2 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190864 SAMN10636474 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.029 host_residential_stratification LongStay treatment Placebo time_point week13 host Homo sapiens isolate Stool age not applicable host_age 95 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 2 host_body_mass_index 28.34 collection_date 2015-08-21 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 28.34 Weight (kg) 60 Appendix A - Charlson co-morbidity 2 Appendix B - Barthel Score 2 Appendix C - FIM 38 Alkaline Phosphatase 75 ALT 7 AST 14 Billirubin 9 Cholesterol 4.7 High Density Lipoprotein(HDL) 0.99 Low Density Lipoprotein (LDL) 3 Triglycerides 1.63 Glucose 5.7 Creatinine 73 Ferritin 54 Thyroid Stimulating Hormone (TSH) 1.34 Urea 10.1 Vitamin B12 383 White blood cells 6.5 HFD_index 0.283724062752892 CRP (mg/L) 60.6 CXCL11 (pg/ml) 686.496323896577 CCL11 (pg/ml) 580.14967061239 IL17A (pg/ml) 1.56533853657894 IFN-gamma (pg/ml) 4.29033211285332 IL-10 (pg/ml) 0.290571747971941 IL-6 (pg/ml) 5.00388804475444 IL-8 (pg/ml) 16.7251582165803 TNF-alpha (pg/ml) 3.02472889366787 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190865 SAMN10636469 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.026 host_residential_stratification LongStay treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 90 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 15 host_body_mass_index 24.72 collection_date 2015-04-27 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.72 Weight (kg) 59.4 Appendix A - Charlson co-morbidity 3 Appendix B - Barthel Score 15 Appendix C - FIM 90 Alkaline Phosphatase 88 ALT 13 AST 19 Billirubin 5 Cholesterol 5 High Density Lipoprotein(HDL) 1.69 Low Density Lipoprotein (LDL) 2.8 Triglycerides 1.03 Glucose 6.4 Creatinine 64 Ferritin 76 Thyroid Stimulating Hormone (TSH) 1.94 Urea 8.7 Vitamin B12 368 White blood cells 4.7 HFD_index not collected CRP (mg/L) 5.2 CXCL11 (pg/ml) 7969.51664195367 CCL11 (pg/ml) 316.183027629136 IL17A (pg/ml) 2.8836098360868 IFN-gamma (pg/ml) 15.9691043688709 IL-10 (pg/ml) 0.393020950312384 IL-6 (pg/ml) 1.22202062022263 IL-8 (pg/ml) 29.4171879067002 TNF-alpha (pg/ml) 5.94744368075295 CD4 (%) 12.5 CD8 (%) 7.4 LPS (EU/ml) 7.64754098360655 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190866 SAMN10636470 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.026 host_residential_stratification LongStay treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 91 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 15 host_body_mass_index 23.89 collection_date 2015-08-17 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23.89 Weight (kg) 57.4 Appendix A - Charlson co-morbidity 3 Appendix B - Barthel Score 15 Appendix C - FIM 90 Alkaline Phosphatase 83 ALT 16 AST not collected Billirubin 8 Cholesterol 5.9 High Density Lipoprotein(HDL) 1.9 Low Density Lipoprotein (LDL) 3.6 Triglycerides 0.93 Glucose 5 Creatinine 74 Ferritin 66 Thyroid Stimulating Hormone (TSH) 3.01 Urea 9 Vitamin B12 250 White blood cells 3.7 HFD_index 0.283303519442466 CRP (mg/L) 2.5 CXCL11 (pg/ml) 7512.87546382281 CCL11 (pg/ml) 395.693424303997 IL17A (pg/ml) 2.52765728124869 IFN-gamma (pg/ml) 9.5355108507889 IL-10 (pg/ml) 0.40324532915396 IL-6 (pg/ml) 1.09642395609607 IL-8 (pg/ml) 15.7212521636975 TNF-alpha (pg/ml) 4.31764202698127 CD4 (%) 22.6 CD8 (%) 8.19999999999999 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190867 SAMN10636471 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.026 host_residential_stratification LongStay treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 91 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 14 host_body_mass_index 23.9 collection_date 2015-11-17 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23.9 Weight (kg) 57.4 Appendix A - Charlson co-morbidity 3 Appendix B - Barthel Score 14 Appendix C - FIM 89 Alkaline Phosphatase 87 ALT 14 AST 20 Billirubin 7 Cholesterol 5.6 High Density Lipoprotein(HDL) 1.94 Low Density Lipoprotein (LDL) 3.3 Triglycerides 0.86 Glucose 5.6 Creatinine 80 Ferritin 44 Thyroid Stimulating Hormone (TSH) 4.2 Urea 8.5 Vitamin B12 361 White blood cells 3.7 HFD_index 0.283303519442466 CRP (mg/L) 2.29999999999999 CXCL11 (pg/ml) 6742.12161298013 CCL11 (pg/ml) 368.674790578226 IL17A (pg/ml) 5.17087984666039 IFN-gamma (pg/ml) 10.2683940175316 IL-10 (pg/ml) 0.425386873563761 IL-6 (pg/ml) 0.693316904363556 IL-8 (pg/ml) 23.4109379068868 TNF-alpha (pg/ml) 4.46100672256322 CD4 (%) 30.1 CD8 (%) 8.25 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190868 SAMN10636472 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.026 host_residential_stratification LongStay treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 91 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 15 host_body_mass_index 23.6 collection_date 2016-01-07 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23.6 Weight (kg) 56.8 Appendix A - Charlson co-morbidity 3 Appendix B - Barthel Score 15 Appendix C - FIM 88 Alkaline Phosphatase 95 ALT 14 AST 23 Billirubin 6 Cholesterol 6 High Density Lipoprotein(HDL) 1.9 Low Density Lipoprotein (LDL) 3.4 Triglycerides 1.47 Glucose 3.5 Creatinine 87 Ferritin 40 Thyroid Stimulating Hormone (TSH) 4.79 Urea 10.5 Vitamin B12 297 White blood cells 5 HFD_index 0.283303519442466 CRP (mg/L) 1.2 CXCL11 (pg/ml) 7761.95407124783 CCL11 (pg/ml) 576.665769284506 IL17A (pg/ml) 4.709429886034 IFN-gamma (pg/ml) 23.9013274124598 IL-10 (pg/ml) 0.367444868427498 IL-6 (pg/ml) 0.958669836027266 IL-8 (pg/ml) 29.766768998055 TNF-alpha (pg/ml) 4.64202044313393 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190869 SAMN10636465 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.025 host_residential_stratification LongStay treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 90 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 3 host_body_mass_index 23.5 collection_date 2014-04-09 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23.5 Weight (kg) 67.9 Appendix A - Charlson co-morbidity 2 Appendix B - Barthel Score 3 Appendix C - FIM 37 Alkaline Phosphatase 115 ALT 6 AST 15 Billirubin 3 Cholesterol 4.4 High Density Lipoprotein(HDL) 1.57 Low Density Lipoprotein (LDL) 2.2 Triglycerides 1.39 Glucose 4.7 Creatinine 125 Ferritin 260 Thyroid Stimulating Hormone (TSH) 1.97 Urea 17.5 Vitamin B12 119 White blood cells 7.2 HFD_index not collected CRP (mg/L) 2.5 CXCL11 (pg/ml) 38.4233357774507 CCL11 (pg/ml) 351.325659608338 IL17A (pg/ml) 4.41050036504189 IFN-gamma (pg/ml) 2.13790839296094 IL-10 (pg/ml) 0.373414607776198 IL-6 (pg/ml) 1.35831695087224 IL-8 (pg/ml) 9.02981604849447 TNF-alpha (pg/ml) 3.98459520995821 CD4 (%) 40.4 CD8 (%) 6.52 LPS (EU/ml) 6.6639344262295 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190870 SAMN10636466 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.025 host_residential_stratification LongStay treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 90 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 3 host_body_mass_index 24.7 collection_date 2015-08-17 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.7 Weight (kg) 71.3 Appendix A - Charlson co-morbidity 2 Appendix B - Barthel Score 3 Appendix C - FIM 41 Alkaline Phosphatase 114 ALT 5 AST 16 Billirubin 4 Cholesterol 4.5 High Density Lipoprotein(HDL) 1.31 Low Density Lipoprotein (LDL) 2.5 Triglycerides 1.47 Glucose 5.3 Creatinine 127 Ferritin 315 Thyroid Stimulating Hormone (TSH) 1.99 Urea 15.5 Vitamin B12 165 White blood cells 7.5 HFD_index 0.463798569461652 CRP (mg/L) 21.6 CXCL11 (pg/ml) 471.975098734038 CCL11 (pg/ml) 360.854778721538 IL17A (pg/ml) 15.2234384990628 IFN-gamma (pg/ml) 12.7261398655363 IL-10 (pg/ml) 0.645250788676668 IL-6 (pg/ml) 2.78632369608954 IL-8 (pg/ml) 17.2096259641668 TNF-alpha (pg/ml) 4.12428670761508 CD4 (%) 43 CD8 (%) 6.01 LPS (EU/ml) 6.54098360655737 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190871 SAMN10636467 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.025 host_residential_stratification LongStay treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 90 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 1 host_body_mass_index 25.15 collection_date 2015-11-16 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 25.15 Weight (kg) 72.7 Appendix A - Charlson co-morbidity 2 Appendix B - Barthel Score 1 Appendix C - FIM 40 Alkaline Phosphatase 111 ALT 8 AST 14 Billirubin 3 Cholesterol 4.2 High Density Lipoprotein(HDL) 1.45 Low Density Lipoprotein (LDL) 2.3 Triglycerides 1.04 Glucose 7.4 Creatinine 130 Ferritin 251 Thyroid Stimulating Hormone (TSH) 2.2 Urea 18.1 Vitamin B12 173 White blood cells 6.7 HFD_index 0.463798569461652 CRP (mg/L) 8.5 CXCL11 (pg/ml) 0 CCL11 (pg/ml) 285.336270828859 IL17A (pg/ml) 8.27898296958129 IFN-gamma (pg/ml) 5.03182683673223 IL-10 (pg/ml) 0.523153718240729 IL-6 (pg/ml) 3.82591976360766 IL-8 (pg/ml) 29.2790199621312 TNF-alpha (pg/ml) 4.07840286338458 CD4 (%) 61.9 CD8 (%) 5.41 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190872 SAMN10636468 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.025 host_residential_stratification LongStay treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 91 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 1 host_body_mass_index 25.6 collection_date 2016-01-14 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 25.6 Weight (kg) 74 Appendix A - Charlson co-morbidity 2 Appendix B - Barthel Score 1 Appendix C - FIM 39 Alkaline Phosphatase 95 ALT 7 AST 15 Billirubin 3 Cholesterol 4.3 High Density Lipoprotein(HDL) 1.55 Low Density Lipoprotein (LDL) 2.2 Triglycerides 1.2 Glucose 7.3 Creatinine 118 Ferritin 147 Thyroid Stimulating Hormone (TSH) 1.97 Urea 17.2 Vitamin B12 210 White blood cells 10.1 HFD_index 0.420940270238603 CRP (mg/L) 2.7 CXCL11 (pg/ml) 0 CCL11 (pg/ml) 365.518268444324 IL17A (pg/ml) 4.51923481285496 IFN-gamma (pg/ml) 2.17451962642526 IL-10 (pg/ml) 0.375120021759869 IL-6 (pg/ml) 2.01014419580908 IL-8 (pg/ml) 14.1679189527233 TNF-alpha (pg/ml) 3.32009967222922 CD4 (%) 51.4 CD8 (%) 4.67 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190873 SAMN10636357 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.018 host_residential_stratification Community treatment Placebo time_point week26 host Homo sapiens isolate Stool age not applicable host_age 67 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 24.4 collection_date 2016-06-09 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.4 Weight (kg) 69 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 76 ALT 17 AST 19 Billirubin 10 Cholesterol 4.7 High Density Lipoprotein(HDL) 0.98 Low Density Lipoprotein (LDL) 3 Triglycerides 1.43 Glucose 4.6 Creatinine 64 Ferritin 155 Thyroid Stimulating Hormone (TSH) 2.06 Urea 5.9 Vitamin B12 248 White blood cells 4.3 HFD_index 0.380606589208836 CRP (mg/L) 1.1 CXCL11 (pg/ml) 112.939393813029 CCL11 (pg/ml) 0 IL17A (pg/ml) 1.22736455392114 IFN-gamma (pg/ml) 3.59006471192205 IL-10 (pg/ml) 0.22055375831403 IL-6 (pg/ml) 0.264221346467752 IL-8 (pg/ml) 21.2525102059249 TNF-alpha (pg/ml) 2.49291525562993 CD4 (%) 41.3 CD8 (%) 15.5 LPS (EU/ml) 0.526685393258426 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190874 SAMN10636389 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.026 host_residential_stratification Community treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 66 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 25.7 collection_date 2016-12-11 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 25.7 Weight (kg) 72.5 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 84 ALT 29 AST 29 Billirubin 12 Cholesterol 4.6 High Density Lipoprotein(HDL) 1.84 Low Density Lipoprotein (LDL) 2.5 Triglycerides 0.63 Glucose 4 Creatinine 65 Ferritin 65 Thyroid Stimulating Hormone (TSH) 2.68 Urea 4.7 Vitamin B12 215 White blood cells 5.5 HFD_index 0.419447059634298 CRP (mg/L) 2.8 CXCL11 (pg/ml) not collected CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 4.7867346851247 IL-10 (pg/ml) 0.0538118254260141 IL-6 (pg/ml) 1.351291214907 IL-8 (pg/ml) 7.00949702936812 TNF-alpha (pg/ml) 0.886058987696268 CD4 (%) 35.2999999999999 CD8 (%) 13.7 LPS (EU/ml) 6.66391412056152 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190875 SAMN10636567 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.030 host_residential_stratification YoungHealthy treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 32 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 21.2 collection_date 2016-05-09 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 21.2 Weight (kg) 71 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 90 ALT 20 AST 24 Billirubin 30 Cholesterol 4.7 High Density Lipoprotein(HDL) 1.25 Low Density Lipoprotein (LDL) 2.7 Triglycerides 1.79 Glucose 5.9 Creatinine 78 Ferritin 147 Thyroid Stimulating Hormone (TSH) 1.96 Urea 5 Vitamin B12 116 White blood cells 7.3 HFD_index 0.487945636253138 CRP (mg/L) 0.5 CXCL11 (pg/ml) 0 CCL11 (pg/ml) 0 IL17A (pg/ml) 9.28065549269244e-06 IFN-gamma (pg/ml) 2.07361689191278 IL-10 (pg/ml) 0.312700139492372 IL-6 (pg/ml) 0.298962792666313 IL-8 (pg/ml) 6.73845784124011 TNF-alpha (pg/ml) 1.94343899466235 CD4 (%) 33.2999999999999 CD8 (%) 46.5 LPS (EU/ml) 12.1967213114754 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190876 SAMN10636521 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.015 host_residential_stratification YoungHealthy treatment Placebo time_point week26 host Homo sapiens isolate Stool age not applicable host_age 24 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 24.3 collection_date 2016-05-25 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.3 Weight (kg) 85.9 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 91 ALT 34 AST 29 Billirubin 8 Cholesterol 4.6 High Density Lipoprotein(HDL) 1.34 Low Density Lipoprotein (LDL) 2.8 Triglycerides 1.14 Glucose 4.8 Creatinine 91 Ferritin 83 Thyroid Stimulating Hormone (TSH) 1.92 Urea 5.1 Vitamin B12 195 White blood cells 6.1 HFD_index 0.516684856237278 CRP (mg/L) 0.9 CXCL11 (pg/ml) 19.8604080592104 CCL11 (pg/ml) 2.79774214078428 IL17A (pg/ml) 7.20854703666628e-06 IFN-gamma (pg/ml) 1.80662213263782 IL-10 (pg/ml) 0.0964531835898668 IL-6 (pg/ml) 0.117294982216683 IL-8 (pg/ml) 4.19993730401696 TNF-alpha (pg/ml) 1.01544372964051 CD4 (%) 34 CD8 (%) 19.6 LPS (EU/ml) 12.5655737704918 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190877 SAMN10636553 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.026 host_residential_stratification YoungHealthy treatment Placebo time_point week32 host Homo sapiens isolate Stool age not applicable host_age 27 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 22.4 collection_date 2016-09-22 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 22.4 Weight (kg) 74 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 81 ALT 24 AST 28 Billirubin 13 Cholesterol 4 High Density Lipoprotein(HDL) 1.17 Low Density Lipoprotein (LDL) 2.5 Triglycerides 0.76 Glucose 5.1 Creatinine 78 Ferritin 83 Thyroid Stimulating Hormone (TSH) 0.73 Urea 4.1 Vitamin B12 479 White blood cells 6.2 HFD_index 0.3675558386679 CRP (mg/L) 0.3 CXCL11 (pg/ml) not applicable CCL11 (pg/ml) 3.37237711500732 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 2.39844430486044 IL-10 (pg/ml) 0.0921655333387931 IL-6 (pg/ml) 0.0673383965899801 IL-8 (pg/ml) 8.16811734522362 TNF-alpha (pg/ml) 1.74340328304865 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 5.01639344262294 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190878 SAMN10636522 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.015 host_residential_stratification YoungHealthy treatment Placebo time_point week32 host Homo sapiens isolate Stool age not applicable host_age 24 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 24.5 collection_date 2016-07-06 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.5 Weight (kg) 86.5 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 88 ALT 26 AST 27 Billirubin 8 Cholesterol 4.2 High Density Lipoprotein(HDL) 1.12 Low Density Lipoprotein (LDL) 2.3 Triglycerides 1.74 Glucose 7.8 Creatinine 87 Ferritin 87 Thyroid Stimulating Hormone (TSH) 1.23 Urea 4.3 Vitamin B12 218 White blood cells 4.8 HFD_index 0.499856481051388 CRP (mg/L) 0.8 CXCL11 (pg/ml) 28.4736192050934 CCL11 (pg/ml) 0.998063904974356 IL17A (pg/ml) 2.21062134341046e-06 IFN-gamma (pg/ml) 2.92618035995212 IL-10 (pg/ml) 0.133072396012763 IL-6 (pg/ml) 0.0747350153487079 IL-8 (pg/ml) 5.46887861527319 TNF-alpha (pg/ml) 1.33459595803614 CD4 (%) 19.3999999999999 CD8 (%) 19.6 LPS (EU/ml) 7.03278688524589 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190879 SAMN10636369 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.021 host_residential_stratification Community treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 71 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 30.1 collection_date 2016-11-08 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 30.1 Weight (kg) 91 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 80 ALT 26 AST 24 Billirubin 10 Cholesterol 6.7 High Density Lipoprotein(HDL) 1.56 Low Density Lipoprotein (LDL) 4.6 Triglycerides 1.15 Glucose 5.8 Creatinine 64 Ferritin 106 Thyroid Stimulating Hormone (TSH) 1.29 Urea 6.1 Vitamin B12 548 White blood cells 5.9 HFD_index 0.382275710397406 CRP (mg/L) 1 CXCL11 (pg/ml) 50.0384851476595 CCL11 (pg/ml) 0 IL17A (pg/ml) 1.09151615309067 IFN-gamma (pg/ml) 10.8376151729708 IL-10 (pg/ml) 0.0834426127468523 IL-6 (pg/ml) 0.426120975377997 IL-8 (pg/ml) 9.52263074353479 TNF-alpha (pg/ml) 1.58091880804085 CD4 (%) 38.2 CD8 (%) 19.3 LPS (EU/ml) 17.9246411483253 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190880 SAMN10636383 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.025 host_residential_stratification Community treatment Placebo time_point week13 host Homo sapiens isolate Stool age not applicable host_age 66 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 24.9 collection_date 2016-06-28 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.9 Weight (kg) 62.2 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 53 ALT 18 AST 23 Billirubin 23 Cholesterol 4.2 High Density Lipoprotein(HDL) 1.66 Low Density Lipoprotein (LDL) 2.1 Triglycerides 0.81 Glucose 5.6 Creatinine 78 Ferritin 93 Thyroid Stimulating Hormone (TSH) 0.64 Urea 5.1 Vitamin B12 408 White blood cells 4.6 HFD_index 0.602075419733169 CRP (mg/L) 1 CXCL11 (pg/ml) 20.3064473790021 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.851029632219474 IFN-gamma (pg/ml) 3.41635185590113 IL-10 (pg/ml) 0.306257741739896 IL-6 (pg/ml) 0.0587515827971199 IL-8 (pg/ml) 15.1564098590661 TNF-alpha (pg/ml) 1.43261460405125 CD4 (%) 25 CD8 (%) 10.1999999999999 LPS (EU/ml) 7.65483071841453 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190881 SAMN10636392 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.027 host_residential_stratification Community treatment Placebo time_point week26 host Homo sapiens isolate Stool age not applicable host_age 83 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 23.2 collection_date 2016-11-16 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23.2 Weight (kg) 53 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 125 Alkaline Phosphatase 53 ALT 18 AST 27 Billirubin 10 Cholesterol 4 High Density Lipoprotein(HDL) 1.57 Low Density Lipoprotein (LDL) 2 Triglycerides 0.93 Glucose 4.9 Creatinine 76 Ferritin 112 Thyroid Stimulating Hormone (TSH) 2.79 Urea 4.3 Vitamin B12 230 White blood cells 5.7 HFD_index 0.373703892324716 CRP (mg/L) 0.8 CXCL11 (pg/ml) not collected CCL11 (pg/ml) 93.8369388899731 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 3.09743993907853 IL-10 (pg/ml) 0.118702115290213 IL-6 (pg/ml) 0.825912587552736 IL-8 (pg/ml) 10.143160184192 TNF-alpha (pg/ml) 0.933802489585914 CD4 (%) 52.8 CD8 (%) 6.09 LPS (EU/ml) 7.40710156895127 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190882 SAMN10636388 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.026 host_residential_stratification Community treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 66 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 25.9 collection_date 2016-11-04 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 25.9 Weight (kg) 73 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 103 ALT 28 AST 29 Billirubin 12 Cholesterol 4.7 High Density Lipoprotein(HDL) 1.7 Low Density Lipoprotein (LDL) 2.4 Triglycerides 1.34 Glucose 4.3 Creatinine 69 Ferritin 61 Thyroid Stimulating Hormone (TSH) 2.72 Urea 5.8 Vitamin B12 187 White blood cells 6 HFD_index 0.367434440165316 CRP (mg/L) 3.2 CXCL11 (pg/ml) not collected CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) 22.4 CD8 (%) 15.2 LPS (EU/ml) 4.02972749793558 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190883 SAMN10636368 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.021 host_residential_stratification Community treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 71 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 30.1 collection_date 2016-10-06 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 30.1 Weight (kg) 91 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 84 ALT 30 AST 22 Billirubin 12 Cholesterol 7.9 High Density Lipoprotein(HDL) 1.67 Low Density Lipoprotein (LDL) 5.6 Triglycerides 1.24 Glucose 5.8 Creatinine 61 Ferritin 98 Thyroid Stimulating Hormone (TSH) 1.63 Urea 4.5 Vitamin B12 483 White blood cells 5.9 HFD_index 0.354345109476361 CRP (mg/L) 2.29999999999999 CXCL11 (pg/ml) 110.796635522877 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.773722090262161 IFN-gamma (pg/ml) 9.13039275579117 IL-10 (pg/ml) 0.161891097519359 IL-6 (pg/ml) 0.542932789521751 IL-8 (pg/ml) 11.1850043687901 TNF-alpha (pg/ml) 1.98759957455922 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 18.3732057416267 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190884 SAMN10636384 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.025 host_residential_stratification Community treatment Placebo time_point week26 host Homo sapiens isolate Stool age not applicable host_age 67 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 24.5 collection_date 2016-10-13 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.5 Weight (kg) 61.2 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 59 ALT 23 AST 15 Billirubin 15 Cholesterol 3.6 High Density Lipoprotein(HDL) 1.55 Low Density Lipoprotein (LDL) 1.7 Triglycerides 0.94 Glucose 4.3 Creatinine 101 Ferritin 94 Thyroid Stimulating Hormone (TSH) 0.57 Urea 8.1 Vitamin B12 481 White blood cells 7.8 HFD_index 0.568137740316897 CRP (mg/L) not collected CXCL11 (pg/ml) 188.101473961849 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.814436856706977 IFN-gamma (pg/ml) 1.04803034793721 IL-10 (pg/ml) 0.409006180215443 IL-6 (pg/ml) 0.298240402713305 IL-8 (pg/ml) 11.9231121749138 TNF-alpha (pg/ml) 1.4501163177857 CD4 (%) 51.3 CD8 (%) 8.27999999999999 LPS (EU/ml) 7.03550784475639 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190885 SAMN10636343 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.013 host_residential_stratification Community treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 65 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 25.8 collection_date 2015-12-14 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 25.8 Weight (kg) 62 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 104 ALT 18 AST 28 Billirubin 8 Cholesterol 6.3 High Density Lipoprotein(HDL) 1.97 Low Density Lipoprotein (LDL) 3.7 Triglycerides 1.3 Glucose 4 Creatinine 62 Ferritin 93 Thyroid Stimulating Hormone (TSH) 1.29 Urea 6.3 Vitamin B12 291 White blood cells 5.1 HFD_index 0.397553467734528 CRP (mg/L) 0.9 CXCL11 (pg/ml) 0 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.740802577739677 IFN-gamma (pg/ml) 4.14241039461932 IL-10 (pg/ml) 0.113305924430327 IL-6 (pg/ml) 0.195074332582114 IL-8 (pg/ml) 10.5199901237312 TNF-alpha (pg/ml) 1.17632460889509 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 16.3995215311004 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190886 SAMN10636537 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.021 host_residential_stratification YoungHealthy treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 64 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 22.8 collection_date 2016-07-20 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 22.8 Weight (kg) 76.5 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 76 ALT 24 AST 26 Billirubin 25 Cholesterol 5.6 High Density Lipoprotein(HDL) 1.36 Low Density Lipoprotein (LDL) 3.7 Triglycerides 1.08 Glucose 4.6 Creatinine 89 Ferritin 68 Thyroid Stimulating Hormone (TSH) 0.7 Urea 6.4 Vitamin B12 774 White blood cells 5.5 HFD_index not collected CRP (mg/L) 1.3 CXCL11 (pg/ml) 21.1111743739548 CCL11 (pg/ml) 3.2488994157891 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 2.09521170037249 IL-10 (pg/ml) 0.141840533700057 IL-6 (pg/ml) 0.698409505569529 IL-8 (pg/ml) 10.9573859932211 TNF-alpha (pg/ml) 1.64156579641087 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 8.6311475409836 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190887 SAMN10636541 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.022 host_residential_stratification YoungHealthy treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 33 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 22.2 collection_date 2016-07-07 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 22.2 Weight (kg) 76 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 53 ALT 18 AST 22 Billirubin 11 Cholesterol 4.5 High Density Lipoprotein(HDL) 1.37 Low Density Lipoprotein (LDL) 2.8 Triglycerides 0.65 Glucose 4.9 Creatinine 105 Ferritin 102 Thyroid Stimulating Hormone (TSH) 1.24 Urea 6.3 Vitamin B12 45 White blood cells 4.5 HFD_index 0.464099141938045 CRP (mg/L) not collected CXCL11 (pg/ml) 24.7590910055321 CCL11 (pg/ml) 2.79774214078428 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 1.73368127416334 IL-10 (pg/ml) 0.0537161695559097 IL-6 (pg/ml) 0.110378120496844 IL-8 (pg/ml) 7.97702424622602 TNF-alpha (pg/ml) 1.70416738845038 CD4 (%) 39.6 CD8 (%) 21.3 LPS (EU/ml) 5.92622950819672 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190888 SAMN10636511 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.010 host_residential_stratification YoungHealthy treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 31 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 22.8 collection_date 2016-04-29 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 22.8 Weight (kg) 72.5 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 100 ALT 25 AST 31 Billirubin 15 Cholesterol 6.2 High Density Lipoprotein(HDL) 1.48 Low Density Lipoprotein (LDL) 4 Triglycerides 1.55 Glucose 3.5 Creatinine 76 Ferritin 164 Thyroid Stimulating Hormone (TSH) 2.49 Urea 7.9 Vitamin B12 277 White blood cells 6.4 HFD_index 0.521087297910206 CRP (mg/L) 0.6 CXCL11 (pg/ml) not applicable CCL11 (pg/ml) 19.8933301880618 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 5.56004191401104 IL-10 (pg/ml) 0.160946291389174 IL-6 (pg/ml) 0.0322392790366847 IL-8 (pg/ml) 5.31689673071363 TNF-alpha (pg/ml) 1.23154389150046 CD4 (%) 42.4 CD8 (%) 22.1 LPS (EU/ml) 21.7868852459016 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190889 SAMN10636397 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.028 host_residential_stratification Community treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 73 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 20.7 collection_date 2017-01-25 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 20.7 Weight (kg) 53 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 107 ALT 22 AST 32 Billirubin 6 Cholesterol 6.4 High Density Lipoprotein(HDL) 1.17 Low Density Lipoprotein (LDL) 4.7 Triglycerides 1.18 Glucose 4.1 Creatinine 59 Ferritin 78 Thyroid Stimulating Hormone (TSH) 1.6 Urea 4.9 Vitamin B12 380 White blood cells 5.8 HFD_index 0.644995528791866 CRP (mg/L) 2.1 CXCL11 (pg/ml) not collected CCL11 (pg/ml) not collected IL17A (pg/ml) not collected IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 7.15937241948802 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190890 SAMN10636398 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.029 host_residential_stratification Community treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 66 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 24.1 collection_date 2016-06-21 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.1 Weight (kg) 68.1 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 94 ALT 18 AST 24 Billirubin 6 Cholesterol 4 High Density Lipoprotein(HDL) 1.97 Low Density Lipoprotein (LDL) 1.6 Triglycerides 0.83 Glucose 6.1 Creatinine 66 Ferritin 31 Thyroid Stimulating Hormone (TSH) 0.9 Urea 5.9 Vitamin B12 323 White blood cells 4.2 HFD_index 0.402422765954897 CRP (mg/L) 1 CXCL11 (pg/ml) 44.8630997455249 CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 3.30723633840268 IL-10 (pg/ml) 0.0797572095825098 IL-6 (pg/ml) 0.275597292952887 IL-8 (pg/ml) 9.68633932285166 TNF-alpha (pg/ml) 0.959032894621687 CD4 (%) 42.5 CD8 (%) 16.5 LPS (EU/ml) 6.29232039636663 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190891 SAMN10636364 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.020 host_residential_stratification Community treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 85 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 20.6 collection_date 2016-08-26 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 20.6 Weight (kg) 66 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 61 ALT 20 AST 26 Billirubin 20 Cholesterol 4.1 High Density Lipoprotein(HDL) 1.21 Low Density Lipoprotein (LDL) 2.5 Triglycerides 0.97 Glucose 5.7 Creatinine 79 Ferritin 66 Thyroid Stimulating Hormone (TSH) 0.72 Urea 11.2 Vitamin B12 241 White blood cells 4 HFD_index 0.466750070774846 CRP (mg/L) 0.1 CXCL11 (pg/ml) 125.594831718539 CCL11 (pg/ml) 0 IL17A (pg/ml) 1.40796425008371 IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 0.842696629213482 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190892 SAMN10636363 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.020 host_residential_stratification Community treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 85 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 20.9 collection_date 2016-05-27 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 20.9 Weight (kg) 67 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 125 Alkaline Phosphatase 60 ALT 30 AST 37 Billirubin 21 Cholesterol 4.1 High Density Lipoprotein(HDL) 1.25 Low Density Lipoprotein (LDL) 2.4 Triglycerides 1.01 Glucose 6.4 Creatinine 72 Ferritin 77 Thyroid Stimulating Hormone (TSH) 1.05 Urea 9.1 Vitamin B12 292 White blood cells 4.2 HFD_index 0.433342702882937 CRP (mg/L) 0.1 CXCL11 (pg/ml) 199.334466305317 CCL11 (pg/ml) 0 IL17A (pg/ml) 1.22169943611726 IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) 44.9 CD8 (%) 5.44 LPS (EU/ml) 0.98314606741573 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190893 SAMN10636374 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.023 host_residential_stratification Community treatment Placebo time_point week0 host Homo sapiens isolate Stool age not applicable host_age 85 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 28.2 collection_date 2016-04-18 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 28.2 Weight (kg) 82.5 Appendix A - Charlson co-morbidity 1 Appendix B - Barthel Score 20 Appendix C - FIM 124 Alkaline Phosphatase 88 ALT 32 AST 27 Billirubin 8 Cholesterol 4.1 High Density Lipoprotein(HDL) not collected Low Density Lipoprotein (LDL) not collected Triglycerides not collected Glucose 4 Creatinine 116 Ferritin 26 Thyroid Stimulating Hormone (TSH) 3.49 Urea 5.7 Vitamin B12 266 White blood cells 8.6 HFD_index 0.4632710001363 CRP (mg/L) 1.5 CXCL11 (pg/ml) 67.651989254274 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.987853272558838 IFN-gamma (pg/ml) 3.82537984030008 IL-10 (pg/ml) 0.165760920339332 IL-6 (pg/ml) 0.924437966442298 IL-8 (pg/ml) 21.6028573780844 TNF-alpha (pg/ml) 3.60052696076783 CD4 (%) 16.3999999999999 CD8 (%) 15.1 LPS (EU/ml) 17.834928229665 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190894 SAMN10636539 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.022 host_residential_stratification YoungHealthy treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 33 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 22.9 collection_date 2016-02-02 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 22.9 Weight (kg) 78.5 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 57 ALT 52 AST 29 Billirubin 9 Cholesterol 5.3 High Density Lipoprotein(HDL) 1.28 Low Density Lipoprotein (LDL) 3.5 Triglycerides 1.15 Glucose 4.6 Creatinine 99 Ferritin 114 Thyroid Stimulating Hormone (TSH) 1.46 Urea 6.2 Vitamin B12 76 White blood cells 6.1 HFD_index 0.417911174669485 CRP (mg/L) 0.7 CXCL11 (pg/ml) 146.487196353853 CCL11 (pg/ml) 93.0671995978655 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 0.98216974122869 IL-10 (pg/ml) 0.138397438485772 IL-6 (pg/ml) 0.357501598448834 IL-8 (pg/ml) 9.78474969378489 TNF-alpha (pg/ml) 0.689292398044171 CD4 (%) 43.7 CD8 (%) 17.6 LPS (EU/ml) 0.140449438202247 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190895 SAMN10636393 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.027 host_residential_stratification Community treatment Placebo time_point week32 host Homo sapiens isolate Stool age not applicable host_age 83 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 23.5 collection_date 2016-12-15 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23.5 Weight (kg) 53.5 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 75 ALT 22 AST 33 Billirubin 9 Cholesterol 4.6 High Density Lipoprotein(HDL) 1.65 Low Density Lipoprotein (LDL) 2.5 Triglycerides 1.07 Glucose 4.9 Creatinine 68 Ferritin 118 Thyroid Stimulating Hormone (TSH) 2.61 Urea 4.7 Vitamin B12 237 White blood cells 5 HFD_index 0.303088908259226 CRP (mg/L) 1.1 CXCL11 (pg/ml) not collected CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 4.34984471449168 IL-10 (pg/ml) 0.236398034736657 IL-6 (pg/ml) 1.10894142087111 IL-8 (pg/ml) 16.2404856019769 TNF-alpha (pg/ml) 1.27006007294091 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 5.92072667217175 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190896 SAMN10636356 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.018 host_residential_stratification Community treatment Placebo time_point week13 host Homo sapiens isolate Stool age not applicable host_age 67 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 24.6 collection_date 2016-03-16 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.6 Weight (kg) 69.4 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 91 ALT 15 AST 21 Billirubin 9 Cholesterol 5 High Density Lipoprotein(HDL) 1.1 Low Density Lipoprotein (LDL) 3.2 Triglycerides 1.42 Glucose 5.7 Creatinine 70 Ferritin 154 Thyroid Stimulating Hormone (TSH) 2.44 Urea 5.2 Vitamin B12 263 White blood cells 5.5 HFD_index 0.380606589208836 CRP (mg/L) 0.5 CXCL11 (pg/ml) not collected CCL11 (pg/ml) 0 IL17A (pg/ml) 2.20811930399045 IFN-gamma (pg/ml) 5.75774881338935 IL-10 (pg/ml) 0.234696775650256 IL-6 (pg/ml) 0.315133818102174 IL-8 (pg/ml) 11.8710673681611 TNF-alpha (pg/ml) 1.70124620702664 CD4 (%) 56.4 CD8 (%) 9.81 LPS (EU/ml) 0.533707865168539 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190897 SAMN10636355 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.018 host_residential_stratification Community treatment Placebo time_point week0 host Homo sapiens isolate Stool age not applicable host_age 67 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 24.9 collection_date 2015-12-12 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.9 Weight (kg) 69.9 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 76 ALT 16 AST 21 Billirubin 9 Cholesterol 5.2 High Density Lipoprotein(HDL) 0.95 Low Density Lipoprotein (LDL) 3.5 Triglycerides 1.84 Glucose 4.8 Creatinine 67 Ferritin 166 Thyroid Stimulating Hormone (TSH) 3.99 Urea 5.5 Vitamin B12 271 White blood cells 4.7 HFD_index 0.380606589208836 CRP (mg/L) 0.8 CXCL11 (pg/ml) 2356.23146921272 CCL11 (pg/ml) not collected IL17A (pg/ml) not collected IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 0.224719101123595 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190898 SAMN10636540 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.022 host_residential_stratification YoungHealthy treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 33 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 22.8 collection_date 2016-05-05 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 22.8 Weight (kg) 78 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 61 ALT 38 AST 30 Billirubin 9 Cholesterol 5.6 High Density Lipoprotein(HDL) 1.57 Low Density Lipoprotein (LDL) 3.3 Triglycerides 1.43 Glucose 6.5 Creatinine 92 Ferritin 88 Thyroid Stimulating Hormone (TSH) 1.53 Urea 5.9 Vitamin B12 85 White blood cells 5.3 HFD_index 0.417911174669485 CRP (mg/L) 1.1 CXCL11 (pg/ml) 27.7715053623664 CCL11 (pg/ml) 1.76472285942581 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 1.76370108521881 IL-10 (pg/ml) 0.0327988361835473 IL-6 (pg/ml) 0.106896680947175 IL-8 (pg/ml) 7.6664863732892 TNF-alpha (pg/ml) 1.66762317172114 CD4 (%) 44.9 CD8 (%) 16.7 LPS (EU/ml) 5.0655737704918 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190899 SAMN10636358 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.018 host_residential_stratification Community treatment Placebo time_point week32 host Homo sapiens isolate Stool age not applicable host_age 67 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 24.3 collection_date 2016-07-14 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.3 Weight (kg) 68.5 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 76 ALT 17 AST 21 Billirubin 9 Cholesterol 5.3 High Density Lipoprotein(HDL) 1.16 Low Density Lipoprotein (LDL) 3.5 Triglycerides 1.2 Glucose 4.6 Creatinine 63 Ferritin 133 Thyroid Stimulating Hormone (TSH) 1.74 Urea 6 Vitamin B12 235 White blood cells 4.9 HFD_index 0.380606589208836 CRP (mg/L) 1 CXCL11 (pg/ml) not applicable CCL11 (pg/ml) 0 IL17A (pg/ml) 0.738472433877061 IFN-gamma (pg/ml) 1.81092816760096 IL-10 (pg/ml) 0.18353046948993 IL-6 (pg/ml) 0.226971640436292 IL-8 (pg/ml) 9.30419827694315 TNF-alpha (pg/ml) 1.66741741302509 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190900 SAMN10636360 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.019 host_residential_stratification Community treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 65 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 22.3 collection_date 2016-06-07 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 22.3 Weight (kg) 67.5 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 80 ALT 17 AST 22 Billirubin 9 Cholesterol 7.2 High Density Lipoprotein(HDL) 1.77 Low Density Lipoprotein (LDL) 4.1 Triglycerides 2.91 Glucose 5 Creatinine 54 Ferritin 104 Thyroid Stimulating Hormone (TSH) 1.65 Urea 4.1 Vitamin B12 168 White blood cells 5.4 HFD_index 0.423037453317589 CRP (mg/L) 0.4 CXCL11 (pg/ml) not collected CCL11 (pg/ml) 0 IL17A (pg/ml) 0.747810053051325 IFN-gamma (pg/ml) 3.68479008064745 IL-10 (pg/ml) 0.0682542669618659 IL-6 (pg/ml) 0.120865548340624 IL-8 (pg/ml) 12.8251375980177 TNF-alpha (pg/ml) 1.75270794467584 CD4 (%) 58 CD8 (%) 10.4 LPS (EU/ml) 0.140449438202247 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190901 SAMN10636359 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.019 host_residential_stratification Community treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 65 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 22.5 collection_date 2016-03-08 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 22.5 Weight (kg) 69 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 80 ALT 15 AST 18 Billirubin 10 Cholesterol 7.6 High Density Lipoprotein(HDL) 2.15 Low Density Lipoprotein (LDL) 4.7 Triglycerides 1.85 Glucose 4.3 Creatinine 53 Ferritin 89 Thyroid Stimulating Hormone (TSH) 2.32 Urea 3.7 Vitamin B12 197 White blood cells 4.7 HFD_index 0.416185030805067 CRP (mg/L) 0.9 CXCL11 (pg/ml) not applicable CCL11 (pg/ml) not collected IL17A (pg/ml) not collected IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) 19.7 CD8 (%) 0.029 LPS (EU/ml) 0.0912921348314606 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190902 SAMN10636362 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.020 host_residential_stratification Community treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 85 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 20.9 collection_date 2016-02-26 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 20.9 Weight (kg) 67 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 62 ALT 21 AST 29 Billirubin 18 Cholesterol 4.5 High Density Lipoprotein(HDL) 1.23 Low Density Lipoprotein (LDL) 2.9 Triglycerides 0.79 Glucose 5.6 Creatinine 71 Ferritin 55 Thyroid Stimulating Hormone (TSH) 1.09 Urea 8.6 Vitamin B12 316 White blood cells 5.4 HFD_index 0.431958385566835 CRP (mg/L) 0.1 CXCL11 (pg/ml) 60.2633467390079 CCL11 (pg/ml) 0 IL17A (pg/ml) 1.21604447391648 IFN-gamma (pg/ml) 6.33247086854887 IL-10 (pg/ml) 0.102568152988199 IL-6 (pg/ml) 1.04517334983413 IL-8 (pg/ml) 9.25867723668982 TNF-alpha (pg/ml) 1.24995428236001 CD4 (%) 35.6 CD8 (%) 5.97 LPS (EU/ml) 0.0421348314606741 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190903 SAMN10636361 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.019 host_residential_stratification Community treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 65 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 22.8 collection_date 2016-09-08 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 22.8 Weight (kg) 69 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 77 ALT 19 AST 19 Billirubin 9 Cholesterol 6.6 High Density Lipoprotein(HDL) 1.97 Low Density Lipoprotein (LDL) 3.9 Triglycerides 1.43 Glucose 4.9 Creatinine 55 Ferritin 77 Thyroid Stimulating Hormone (TSH) 1.39 Urea 3.9 Vitamin B12 150 White blood cells 5 HFD_index 0.423444938818202 CRP (mg/L) 0.3 CXCL11 (pg/ml) not applicable CCL11 (pg/ml) 0 IL17A (pg/ml) 0.752495886387241 IFN-gamma (pg/ml) 2.26795668397477 IL-10 (pg/ml) 0.0871394531002322 IL-6 (pg/ml) 0.147907578755748 IL-8 (pg/ml) 10.3813814906005 TNF-alpha (pg/ml) 1.14290572426232 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190904 SAMN10636501 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.007 host_residential_stratification YoungHealthy treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 39 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 19.1 collection_date 2015-10-23 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 19.1 Weight (kg) 51.5 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 54 ALT 12 AST 20 Billirubin 23 Cholesterol 5.3 High Density Lipoprotein(HDL) 1.73 Low Density Lipoprotein (LDL) 3.3 Triglycerides 0.75 Glucose 4 Creatinine 59 Ferritin 48 Thyroid Stimulating Hormone (TSH) 2.13 Urea 6 Vitamin B12 682 White blood cells 9.3 HFD_index 0.568891190035173 CRP (mg/L) 0.5 CXCL11 (pg/ml) 3.69280209571022 CCL11 (pg/ml) 4.05375722677536 IL17A (pg/ml) 1.27757264574371e-06 IFN-gamma (pg/ml) 4.13030480306008 IL-10 (pg/ml) 0.337303495605946 IL-6 (pg/ml) 0.199890011578735 IL-8 (pg/ml) 7.03735283495776 TNF-alpha (pg/ml) 0.934840865892987 CD4 (%) 54.7 CD8 (%) 17.1 LPS (EU/ml) 5.43442622950819 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190905 SAMN10636502 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.007 host_residential_stratification YoungHealthy treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 39 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 19.6 collection_date 2016-01-20 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 19.6 Weight (kg) 54 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 48 ALT 11 AST 20 Billirubin 14 Cholesterol 5.7 High Density Lipoprotein(HDL) 1.7 Low Density Lipoprotein (LDL) 3.7 Triglycerides 0.68 Glucose 4.1 Creatinine 55 Ferritin 28 Thyroid Stimulating Hormone (TSH) 3.55 Urea 4.4 Vitamin B12 553 White blood cells 7.4 HFD_index 0.6136678293155 CRP (mg/L) 0.4 CXCL11 (pg/ml) 8.4416624453847 CCL11 (pg/ml) 28.7348325360787 IL17A (pg/ml) 2.92703113998055e-07 IFN-gamma (pg/ml) 7.19564896491221 IL-10 (pg/ml) 0.109382158610623 IL-6 (pg/ml) 0.106896680947175 IL-8 (pg/ml) 6.33286073874204 TNF-alpha (pg/ml) 0.536748587788306 CD4 (%) 58.2 CD8 (%) 15 LPS (EU/ml) 6.90983606557377 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190906 SAMN10636377 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.023 host_residential_stratification Community treatment Placebo time_point week32 host Homo sapiens isolate Stool age not applicable host_age 86 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 28.4 collection_date 2016-11-20 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 28.4 Weight (kg) 83 Appendix A - Charlson co-morbidity 1 Appendix B - Barthel Score 20 Appendix C - FIM 125 Alkaline Phosphatase 85 ALT 39 AST 35 Billirubin 9 Cholesterol 4.3 High Density Lipoprotein(HDL) 1.53 Low Density Lipoprotein (LDL) 2 Triglycerides 1.68 Glucose 5.8 Creatinine 118 Ferritin 18 Thyroid Stimulating Hormone (TSH) 1.83 Urea 7.1 Vitamin B12 269 White blood cells 9.4 HFD_index 0.352730338211577 CRP (mg/L) 1.4 CXCL11 (pg/ml) 782.154550372565 CCL11 (pg/ml) 0 IL17A (pg/ml) 1.01668532409788 IFN-gamma (pg/ml) 4.30367075903722 IL-10 (pg/ml) 0.362629867775101 IL-6 (pg/ml) 3.24424254934886 IL-8 (pg/ml) 21.6272832244538 TNF-alpha (pg/ml) 2.85281932949582 CD4 (%) 19.8 CD8 (%) 15.6 LPS (EU/ml) 8.89347646573079 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190907 SAMN10636566 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.030 host_residential_stratification YoungHealthy treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 32 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score not collected host_body_mass_index 21.2 collection_date 2016-02-08 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 21.2 Weight (kg) 71 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 87 ALT 29 AST 27 Billirubin 52 Cholesterol 4.9 High Density Lipoprotein(HDL) 1.51 Low Density Lipoprotein (LDL) 3 Triglycerides 0.97 Glucose 4.6 Creatinine 84 Ferritin 152 Thyroid Stimulating Hormone (TSH) 1.94 Urea 4.8 Vitamin B12 128 White blood cells 6.7 HFD_index 0.487945636253138 CRP (mg/L) 0.7 CXCL11 (pg/ml) not collected CCL11 (pg/ml) not collected IL17A (pg/ml) not collected IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) 36.5 CD8 (%) 39.2 LPS (EU/ml) 14.1327751196172 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190908 SAMN10636505 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.008 host_residential_stratification YoungHealthy treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 28 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 19.4 collection_date 2015-10-23 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 19.4 Weight (kg) 56 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 54 ALT 11 AST 20 Billirubin 10 Cholesterol 6 High Density Lipoprotein(HDL) 2.17 Low Density Lipoprotein (LDL) 3.5 Triglycerides 0.57 Glucose 3.3 Creatinine 78 Ferritin 22 Thyroid Stimulating Hormone (TSH) 1.32 Urea 5.2 Vitamin B12 270 White blood cells 4.3 HFD_index 0.555587866102754 CRP (mg/L) 0.4 CXCL11 (pg/ml) 0 CCL11 (pg/ml) 3.80122760512678 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 3.74479402096226 IL-10 (pg/ml) 0.132586256483451 IL-6 (pg/ml) 0 IL-8 (pg/ml) 7.45217346664798 TNF-alpha (pg/ml) 0.628924505853859 CD4 (%) 47.1 CD8 (%) 18.3999999999999 LPS (EU/ml) 11.7049180327868 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190909 SAMN10636394 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.028 host_residential_stratification Community treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 72 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 19.9 collection_date 2016-06-15 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 19.9 Weight (kg) 51 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 125 Alkaline Phosphatase 103 ALT 56 AST 48 Billirubin 10 Cholesterol 5.5 High Density Lipoprotein(HDL) 1.15 Low Density Lipoprotein (LDL) 4 Triglycerides 0.93 Glucose 5.1 Creatinine 58 Ferritin 82 Thyroid Stimulating Hormone (TSH) 1.81 Urea 4 Vitamin B12 312 White blood cells 5.1 HFD_index 0.623481780375381 CRP (mg/L) 0.4 CXCL11 (pg/ml) not collected CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 4.30367075903722 IL-10 (pg/ml) 0.028743565444445 IL-6 (pg/ml) 0.412385132845639 IL-8 (pg/ml) 6.40614753751671 TNF-alpha (pg/ml) 0.949734929387766 CD4 (%) 46.9 CD8 (%) 14.5 LPS (EU/ml) 6.16845582163501 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190910 SAMN10636378 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.024 host_residential_stratification Community treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 68 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 27.9 collection_date 2016-04-19 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 27.9 Weight (kg) 71.5 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 67 ALT 15 AST 25 Billirubin 12 Cholesterol 5 High Density Lipoprotein(HDL) 1.63 Low Density Lipoprotein (LDL) not collected Triglycerides 0.93 Glucose 6.9 Creatinine 68 Ferritin 207 Thyroid Stimulating Hormone (TSH) 4.68 Urea 7 Vitamin B12 268 White blood cells 4.8 HFD_index 0.339822248608825 CRP (mg/L) 4.8 CXCL11 (pg/ml) 700.186649257806 CCL11 (pg/ml) 0 IL17A (pg/ml) 1.18232856660996 IFN-gamma (pg/ml) 3.69617177193861 IL-10 (pg/ml) 0.100429766399078 IL-6 (pg/ml) 0 IL-8 (pg/ml) 0.928107724100719 TNF-alpha (pg/ml) 0.63820701590895 CD4 (%) 44.6 CD8 (%) 14.4 LPS (EU/ml) 6.78777869529314 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190911 SAMN10636434 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.011 host_residential_stratification LongStay treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 93 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 4 host_body_mass_index 28 collection_date 2015-02-11 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 28 Weight (kg) 70.2 Appendix A - Charlson co-morbidity 1 Appendix B - Barthel Score 4 Appendix C - FIM 52 Alkaline Phosphatase 152 ALT 29 AST 34 Billirubin 5 Cholesterol 5.8 High Density Lipoprotein(HDL) 1.06 Low Density Lipoprotein (LDL) 3.3 Triglycerides 2.97 Glucose 6.2 Creatinine 97 Ferritin 83 Thyroid Stimulating Hormone (TSH) 1.69 Urea 8.5 Vitamin B12 205 White blood cells 6.2 HFD_index not collected CRP (mg/L) 78 CXCL11 (pg/ml) 1470.08932459761 CCL11 (pg/ml) 517.620092198358 IL17A (pg/ml) 1.70324152255178 IFN-gamma (pg/ml) 26.1985410243636 IL-10 (pg/ml) 0.984703798321871 IL-6 (pg/ml) 4.41845650946067 IL-8 (pg/ml) 20.1679875449039 TNF-alpha (pg/ml) 4.21202494151034 CD4 (%) 43.4 CD8 (%) 18.6 LPS (EU/ml) 8.01639344262295 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190912 SAMN10636433 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.010 host_residential_stratification LongStay treatment Placebo time_point week32 host Homo sapiens isolate Stool age not applicable host_age 79 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 6 host_body_mass_index 46.4 collection_date 2015-10-06 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 46.4 Weight (kg) 130.9 Appendix A - Charlson co-morbidity 2 Appendix B - Barthel Score 6 Appendix C - FIM 61 Alkaline Phosphatase 156 ALT 13 AST 16 Billirubin 4 Cholesterol 2.7 High Density Lipoprotein(HDL) 0.85 Low Density Lipoprotein (LDL) 1.1 Triglycerides 1.67 Glucose 8 Creatinine 66 Ferritin 193 Thyroid Stimulating Hormone (TSH) 4.97 Urea 6.3 Vitamin B12 174 White blood cells 5.6 HFD_index 0.483648416095847 CRP (mg/L) 28.8 CXCL11 (pg/ml) 810.927897261761 CCL11 (pg/ml) 391.325093363096 IL17A (pg/ml) 1.39962158859339 IFN-gamma (pg/ml) 9.17716109709108 IL-10 (pg/ml) 0.203981398458519 IL-6 (pg/ml) 1.77242814553301 IL-8 (pg/ml) 17.4959767683338 TNF-alpha (pg/ml) 3.47051246562064 CD4 (%) 39.7 CD8 (%) 22.7 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190913 SAMN10636381 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.024 host_residential_stratification Community treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 69 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 27 collection_date 2016-11-21 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 27 Weight (kg) 69 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 71 ALT 16 AST 25 Billirubin 12 Cholesterol 4.9 High Density Lipoprotein(HDL) 1.72 Low Density Lipoprotein (LDL) 2.8 Triglycerides 0.81 Glucose 4.8 Creatinine 67 Ferritin 179 Thyroid Stimulating Hormone (TSH) 3.92 Urea 7.4 Vitamin B12 239 White blood cells 3.2 HFD_index 0.300865681004194 CRP (mg/L) 3 CXCL11 (pg/ml) 196.851850677614 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.828999203612267 IFN-gamma (pg/ml) 5.88811816383041 IL-10 (pg/ml) 0.127914867308196 IL-6 (pg/ml) 0.289765646673434 IL-8 (pg/ml) 13.3649107809265 TNF-alpha (pg/ml) 1.28615220105893 CD4 (%) 44.6 CD8 (%) 10.7 LPS (EU/ml) 6.54004954582989 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190914 SAMN10636370 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.022 host_residential_stratification Community treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 67 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 24.9 collection_date 2016-03-23 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.9 Weight (kg) 86.3 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 68 ALT 21 AST 29 Billirubin 10 Cholesterol 5.5 High Density Lipoprotein(HDL) 1.3 Low Density Lipoprotein (LDL) 3.7 Triglycerides 1.16 Glucose 5 Creatinine 77 Ferritin 142 Thyroid Stimulating Hormone (TSH) 3.8 Urea 5.8 Vitamin B12 275 White blood cells 6.2 HFD_index 0.443497690576498 CRP (mg/L) 2.2 CXCL11 (pg/ml) 5.39958893954568 CCL11 (pg/ml) 0 IL17A (pg/ml) 1.00354002798133 IFN-gamma (pg/ml) 5.60007636385646 IL-10 (pg/ml) 0.0940339529124303 IL-6 (pg/ml) 1.24067952004036 IL-8 (pg/ml) 6.68451939768139 TNF-alpha (pg/ml) 2.10743819606015 CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 18.3732057416267 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190915 SAMN10636554 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.027 host_residential_stratification YoungHealthy treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 62 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 26.2 collection_date 2016-02-08 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 26.2 Weight (kg) 67 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 39 ALT 21 AST 30 Billirubin 11 Cholesterol 4.3 High Density Lipoprotein(HDL) 1.6 Low Density Lipoprotein (LDL) 2.4 Triglycerides 0.66 Glucose 4.8 Creatinine 58 Ferritin 31 Thyroid Stimulating Hormone (TSH) 2.37 Urea 4.7 Vitamin B12 223 White blood cells 4.5 HFD_index 0.491206965082688 CRP (mg/L) 1.8 CXCL11 (pg/ml) 60.0486089692207 CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 3.95287078431886 IL-10 (pg/ml) 0.139681088966507 IL-6 (pg/ml) 0.0701081171987379 IL-8 (pg/ml) 16.2336765552213 TNF-alpha (pg/ml) 1.55381012922952 CD4 (%) 48.1 CD8 (%) 14.7 LPS (EU/ml) 0.21067415730337 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190916 SAMN10636546 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.024 host_residential_stratification YoungHealthy treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 23 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 27.6 collection_date 2016-05-05 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 27.6 Weight (kg) 78 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 51 ALT 15 AST 22 Billirubin 8 Cholesterol 4.7 High Density Lipoprotein(HDL) 1.9 Low Density Lipoprotein (LDL) 2.5 Triglycerides 0.6 Glucose 5.1 Creatinine 73 Ferritin 39 Thyroid Stimulating Hormone (TSH) 2.57 Urea 4.7 Vitamin B12 271 White blood cells 4.1 HFD_index 0.659246621813683 CRP (mg/L) 0.4 CXCL11 (pg/ml) 0.877875575870963 CCL11 (pg/ml) 13.8394261636429 IL17A (pg/ml) 3.85933548410391e-06 IFN-gamma (pg/ml) 1.54547785417567 IL-10 (pg/ml) 0.12288603901869 IL-6 (pg/ml) 0 IL-8 (pg/ml) 4.30864625435452 TNF-alpha (pg/ml) 1.0353783674344 CD4 (%) 50.8 CD8 (%) 22.6 LPS (EU/ml) 6.90983606557377 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190917 SAMN10636463 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.024 host_residential_stratification LongStay treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 86 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 8 host_body_mass_index 26.4 collection_date 2015-11-23 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 26.4 Weight (kg) 72 Appendix A - Charlson co-morbidity 3 Appendix B - Barthel Score 8 Appendix C - FIM 74 Alkaline Phosphatase 99 ALT 9 AST not collected Billirubin 8 Cholesterol 3.1 High Density Lipoprotein(HDL) 0.7 Low Density Lipoprotein (LDL) 1.9 Triglycerides 1.12 Glucose 7.2 Creatinine 122 Ferritin 79 Thyroid Stimulating Hormone (TSH) 1.62 Urea 17.4 Vitamin B12 394 White blood cells 14.9 HFD_index 0.225023993049068 CRP (mg/L) 50.3 CXCL11 (pg/ml) 532.74302554455 CCL11 (pg/ml) 590.078125690901 IL17A (pg/ml) 19.0627786884069 IFN-gamma (pg/ml) 4.37091868597205 IL-10 (pg/ml) 1.09666021125703 IL-6 (pg/ml) 23.1807787047985 IL-8 (pg/ml) 21.7012414794669 TNF-alpha (pg/ml) 4.16816226924455 CD4 (%) 19.1 CD8 (%) 6.81 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190918 SAMN10636464 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.024 host_residential_stratification LongStay treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 86 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 7 host_body_mass_index 24.24 collection_date 2016-01-08 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.24 Weight (kg) 66 Appendix A - Charlson co-morbidity 3 Appendix B - Barthel Score 7 Appendix C - FIM 54 Alkaline Phosphatase not collected ALT not collected AST not collected Billirubin not collected Cholesterol not collected High Density Lipoprotein(HDL) not collected Low Density Lipoprotein (LDL) not collected Triglycerides not collected Glucose not collected Creatinine not collected Ferritin not collected Thyroid Stimulating Hormone (TSH) not collected Urea not collected Vitamin B12 not collected White blood cells not collected HFD_index 0.217020229824352 CRP (mg/L) not collected CXCL11 (pg/ml) not collected CCL11 (pg/ml) not collected IL17A (pg/ml) not collected IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190919 SAMN10636385 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.025 host_residential_stratification Community treatment Placebo time_point week32 host Homo sapiens isolate Stool age not applicable host_age 67 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 23.6 collection_date 2016-11-22 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23.6 Weight (kg) 59 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 60 ALT 25 AST 25 Billirubin 24 Cholesterol 4.1 High Density Lipoprotein(HDL) 1.54 Low Density Lipoprotein (LDL) not collected Triglycerides 0.72 Glucose 4.5 Creatinine 80 Ferritin 59 Thyroid Stimulating Hormone (TSH) 0.66 Urea 6.2 Vitamin B12 291 White blood cells 5.3 HFD_index 0.590985858139054 CRP (mg/L) 1.2 CXCL11 (pg/ml) not collected CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 3.00418160517766 IL-10 (pg/ml) 0.266590668273765 IL-6 (pg/ml) 0.24135143506154 IL-8 (pg/ml) 12.8477031861117 TNF-alpha (pg/ml) 1.46223693611467 CD4 (%) 33.1 CD8 (%) 16.3999999999999 LPS (EU/ml) 3.98843930635838 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190920 SAMN10636386 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.026 host_residential_stratification Community treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 65 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 26.6 collection_date 2016-05-05 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 26.6 Weight (kg) 75 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 93 ALT 32 AST 24 Billirubin 13 Cholesterol 4.5 High Density Lipoprotein(HDL) 1.78 Low Density Lipoprotein (LDL) 2.3 Triglycerides 0.8 Glucose 5.7 Creatinine 64 Ferritin 71 Thyroid Stimulating Hormone (TSH) 3.15 Urea 6.1 Vitamin B12 195 White blood cells 6.5 HFD_index 0.381730690587845 CRP (mg/L) 3.5 CXCL11 (pg/ml) 0 CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 3.47291314979309 IL-10 (pg/ml) 0.209847242819905 IL-6 (pg/ml) 0.86231352956741 IL-8 (pg/ml) 9.26334551037754 TNF-alpha (pg/ml) 1.55526889084206 CD4 (%) 29.1 CD8 (%) 29.7 LPS (EU/ml) 4.36003303055326 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190921 SAMN10636387 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.026 host_residential_stratification Community treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 66 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 26.4 collection_date 2016-08-07 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 26.4 Weight (kg) 74.5 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 125 Alkaline Phosphatase 87 ALT 30 AST 25 Billirubin 11 Cholesterol 4.3 High Density Lipoprotein(HDL) 1.53 Low Density Lipoprotein (LDL) 2.3 Triglycerides 0.99 Glucose 6 Creatinine 63 Ferritin 67 Thyroid Stimulating Hormone (TSH) 2.29 Urea 4.5 Vitamin B12 214 White blood cells 6.4 HFD_index 0.381730690587845 CRP (mg/L) 2.7 CXCL11 (pg/ml) not collected CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) not collected CD8 (%) not collected LPS (EU/ml) 4.73162675474814 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190922 SAMN10636545 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.024 host_residential_stratification YoungHealthy treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 22 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 25.9 collection_date 2016-02-03 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 25.9 Weight (kg) 76.5 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 52 ALT 21 AST 26 Billirubin 6 Cholesterol 4.8 High Density Lipoprotein(HDL) 1.55 Low Density Lipoprotein (LDL) 2.9 Triglycerides 1.55 Glucose 4.4 Creatinine 78 Ferritin 39 Thyroid Stimulating Hormone (TSH) 3.08 Urea 4.4 Vitamin B12 251 White blood cells 7.5 HFD_index 0.659246621813683 CRP (mg/L) 1.4 CXCL11 (pg/ml) 1274.08894758853 CCL11 (pg/ml) 0 IL17A (pg/ml) 0 IFN-gamma (pg/ml) not collected IL-10 (pg/ml) not collected IL-6 (pg/ml) not collected IL-8 (pg/ml) not collected TNF-alpha (pg/ml) not collected CD4 (%) 46.1 CD8 (%) 22.6 LPS (EU/ml) 1.68539325842696 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190923 SAMN10636458 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.023 host_residential_stratification LongStay treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 83 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 4 host_body_mass_index 19.75 collection_date 2015-04-24 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 19.75 Weight (kg) 60.8 Appendix A - Charlson co-morbidity 2 Appendix B - Barthel Score 4 Appendix C - FIM 59 Alkaline Phosphatase 161 ALT 11 AST 19 Billirubin 8 Cholesterol 4.8 High Density Lipoprotein(HDL) 1.28 Low Density Lipoprotein (LDL) 3.2 Triglycerides 0.69 Glucose 5.1 Creatinine 74 Ferritin 89 Thyroid Stimulating Hormone (TSH) 2.85 Urea 7.5 Vitamin B12 255 White blood cells 7 HFD_index not collected CRP (mg/L) 2.5 CXCL11 (pg/ml) 415.662795010797 CCL11 (pg/ml) 280.434485355883 IL17A (pg/ml) 4.00239329640756 IFN-gamma (pg/ml) 4.49618310064145 IL-10 (pg/ml) 0.389612070604028 IL-6 (pg/ml) 1.67595671211323 IL-8 (pg/ml) 9.90562819918391 TNF-alpha (pg/ml) 3.26992017955467 CD4 (%) 44.2 CD8 (%) 13.6 LPS (EU/ml) 7.40163934426229 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190924 SAMN10636457 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.020 host_residential_stratification LongStay treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 84 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 8 host_body_mass_index 23.8 collection_date 2015-12-11 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 23.8 Weight (kg) 60.8 Appendix A - Charlson co-morbidity 2 Appendix B - Barthel Score 8 Appendix C - FIM 30 Alkaline Phosphatase 143 ALT 16 AST 21 Billirubin 6 Cholesterol 5.3 High Density Lipoprotein(HDL) 1.29 Low Density Lipoprotein (LDL) 3 Triglycerides 2.22 Glucose 5.2 Creatinine 80 Ferritin 40 Thyroid Stimulating Hormone (TSH) 0.94 Urea 7.5 Vitamin B12 190 White blood cells 8.6 HFD_index 0.277920593881463 CRP (mg/L) 5.4 CXCL11 (pg/ml) 2847.82366711317 CCL11 (pg/ml) 413.189304008973 IL17A (pg/ml) 3.75724423695749 IFN-gamma (pg/ml) 16.2269098585497 IL-10 (pg/ml) 2.06169097758307 IL-6 (pg/ml) 2.57651929120665 IL-8 (pg/ml) 18.7529130179892 TNF-alpha (pg/ml) 9.98865500133138 CD4 (%) 44.3 CD8 (%) 13.2 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190925 SAMN10636455 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.020 host_residential_stratification LongStay treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 84 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 8 host_body_mass_index 24 collection_date 2015-08-21 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24 Weight (kg) 61.5 Appendix A - Charlson co-morbidity 2 Appendix B - Barthel Score 8 Appendix C - FIM 30 Alkaline Phosphatase 148 ALT 25 AST 23 Billirubin 5 Cholesterol 5.3 High Density Lipoprotein(HDL) 1.19 Low Density Lipoprotein (LDL) 3.1 Triglycerides 2.19 Glucose 6.5 Creatinine 59 Ferritin 31 Thyroid Stimulating Hormone (TSH) 1.82 Urea 9.6 Vitamin B12 209 White blood cells 9 HFD_index 0.281426635161971 CRP (mg/L) 5.09999999999999 CXCL11 (pg/ml) 1958.09041396366 CCL11 (pg/ml) 483.735679705427 IL17A (pg/ml) 4.165704899014 IFN-gamma (pg/ml) 6.21305358929464 IL-10 (pg/ml) 1.17570171850364 IL-6 (pg/ml) 1.12745224516939 IL-8 (pg/ml) 8.94489792695076 TNF-alpha (pg/ml) 4.50876618080607 CD4 (%) 44.9 CD8 (%) 15.6 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190926 SAMN10636456 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.020 host_residential_stratification LongStay treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 84 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 8 host_body_mass_index 24.5 collection_date missing env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 24.5 Weight (kg) 62.7 Appendix A - Charlson co-morbidity 2 Appendix B - Barthel Score 8 Appendix C - FIM 30 Alkaline Phosphatase 154 ALT 19 AST 19 Billirubin 5 Cholesterol 4.8 High Density Lipoprotein(HDL) 1.28 Low Density Lipoprotein (LDL) 2.6 Triglycerides 1.9 Glucose 7.4 Creatinine 75 Ferritin 38 Thyroid Stimulating Hormone (TSH) 1.19 Urea 9.2 Vitamin B12 174 White blood cells 8.2 HFD_index 0.277920593881463 CRP (mg/L) 7.1 CXCL11 (pg/ml) 1979.43660118424 CCL11 (pg/ml) 331.824287420098 IL17A (pg/ml) 1.78590518594351 IFN-gamma (pg/ml) 7.21987096389135 IL-10 (pg/ml) 1.54656331838118 IL-6 (pg/ml) 2.25618895182575 IL-8 (pg/ml) 12.7976935011125 TNF-alpha (pg/ml) 5.3324982627104 CD4 (%) 42.7 CD8 (%) 6.6 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190927 SAMN10636462 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.024 host_residential_stratification LongStay treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 86 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 11 host_body_mass_index 29.6 collection_date 2015-08-27 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 29.6 Weight (kg) 72 Appendix A - Charlson co-morbidity 3 Appendix B - Barthel Score 11 Appendix C - FIM 74 Alkaline Phosphatase 142 ALT 7 AST 15 Billirubin 4 Cholesterol 3.5 High Density Lipoprotein(HDL) 0.69 Low Density Lipoprotein (LDL) 2.1 Triglycerides 1.58 Glucose 6.2 Creatinine 127 Ferritin 22 Thyroid Stimulating Hormone (TSH) 2.26 Urea 7.7 Vitamin B12 240 White blood cells 10.1 HFD_index 0.225023993049068 CRP (mg/L) 2.5 CXCL11 (pg/ml) 348.309747703304 CCL11 (pg/ml) 255.639683318215 IL17A (pg/ml) 1.45489046162767 IFN-gamma (pg/ml) 4.90701091876942 IL-10 (pg/ml) 0.260608998013713 IL-6 (pg/ml) 1.64827965021022 IL-8 (pg/ml) 17.7873211225715 TNF-alpha (pg/ml) 6.03232446953979 CD4 (%) 40.4 CD8 (%) 17.3 LPS (EU/ml) 2.22950819672131 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190928 SAMN10636461 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.024 host_residential_stratification LongStay treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 86 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 12 host_body_mass_index 29.64 collection_date 2015-04-27 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 29.64 Weight (kg) 72.2 Appendix A - Charlson co-morbidity 3 Appendix B - Barthel Score 12 Appendix C - FIM 72 Alkaline Phosphatase 133 ALT 7 AST not collected Billirubin 6 Cholesterol 3.4 High Density Lipoprotein(HDL) 0.68 Low Density Lipoprotein (LDL) 2 Triglycerides 1.57 Glucose not collected Creatinine 120 Ferritin 27 Thyroid Stimulating Hormone (TSH) 1.53 Urea 10.2 Vitamin B12 279 White blood cells 9.4 HFD_index not collected CRP (mg/L) 2.5 CXCL11 (pg/ml) 308.435062271298 CCL11 (pg/ml) 281.235709395216 IL17A (pg/ml) 2.00607864675022 IFN-gamma (pg/ml) 3.59881475051408 IL-10 (pg/ml) 0.355501631665044 IL-6 (pg/ml) 2.06424357611521 IL-8 (pg/ml) 8.87496522145663 TNF-alpha (pg/ml) 6.65313991846346 CD4 (%) 38.6 CD8 (%) 14.4 LPS (EU/ml) 2.47540983606557 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190929 SAMN10636460 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.023 host_residential_stratification LongStay treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 83 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 4 host_body_mass_index 20.11 collection_date 2016-01-08 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 20.11 Weight (kg) 61.6 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 4 Appendix C - FIM 60 Alkaline Phosphatase 185 ALT 9 AST not collected Billirubin 8 Cholesterol 4.9 High Density Lipoprotein(HDL) 1.24 Low Density Lipoprotein (LDL) 3.2 Triglycerides 0.99 Glucose 9 Creatinine 74 Ferritin 77 Thyroid Stimulating Hormone (TSH) 4.43 Urea 7.8 Vitamin B12 324 White blood cells 6 HFD_index 0.265897979358725 CRP (mg/L) 6.5 CXCL11 (pg/ml) 169.941590895642 CCL11 (pg/ml) 219.005903909299 IL17A (pg/ml) 5.27936799700002 IFN-gamma (pg/ml) 4.82671955048856 IL-10 (pg/ml) 0.296559377926725 IL-6 (pg/ml) 1.42487543965586 IL-8 (pg/ml) 13.5186055254159 TNF-alpha (pg/ml) 3.21570215567126 CD4 (%) 43 CD8 (%) 10.4 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190930 SAMN10636301 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.002 host_residential_stratification Community treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 75 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 32.5 collection_date 2016-04-23 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 32.5 Weight (kg) 110 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 69 ALT 39 AST 31 Billirubin 22 Cholesterol 3.8 High Density Lipoprotein(HDL) 1.44 Low Density Lipoprotein (LDL) not collected Triglycerides 1.15 Glucose 5.9 Creatinine 118 Ferritin 99 Thyroid Stimulating Hormone (TSH) 4.22 Urea 5.7 Vitamin B12 149 White blood cells 6 HFD_index 0.275361077181374 CRP (mg/L) 1 CXCL11 (pg/ml) 0 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.938812768335381 IFN-gamma (pg/ml) 3.65445417423204 IL-10 (pg/ml) 0.407827339603028 IL-6 (pg/ml) 0.510552947405848 IL-8 (pg/ml) 19.8676341169475 TNF-alpha (pg/ml) 2.57245053471884 CD4 (%) 51.2 CD8 (%) 9.22 LPS (EU/ml) 30.9945678782085 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190931 SAMN10636459 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id IEM.023 host_residential_stratification LongStay treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 83 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 4 host_body_mass_index 20 collection_date 2015-11-18 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 20 Weight (kg) 61.1 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 4 Appendix C - FIM 60 Alkaline Phosphatase 161 ALT 15 AST 20 Billirubin 9 Cholesterol 5.3 High Density Lipoprotein(HDL) 1.28 Low Density Lipoprotein (LDL) 3.7 Triglycerides 0.73 Glucose 5.6 Creatinine 74 Ferritin 88 Thyroid Stimulating Hormone (TSH) 4.29 Urea 7.4 Vitamin B12 259 White blood cells 6.5 HFD_index 0.265897979358725 CRP (mg/L) 5 CXCL11 (pg/ml) 483.371921677967 CCL11 (pg/ml) 425.300906906358 IL17A (pg/ml) 2.71940787368875 IFN-gamma (pg/ml) 6.83183295920991 IL-10 (pg/ml) 0.311949062059567 IL-6 (pg/ml) 1.321857921166 IL-8 (pg/ml) 29.8333557993803 TNF-alpha (pg/ml) 4.58435651316863 CD4 (%) 39 CD8 (%) 9.94 LPS (EU/ml) not collected BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190932 SAMN10636302 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.002 host_residential_stratification Community treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 75 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 33.7 collection_date 2016-06-14 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 33.7 Weight (kg) 114 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 125 Alkaline Phosphatase 57 ALT 43 AST 35 Billirubin 17 Cholesterol 4.1 High Density Lipoprotein(HDL) 1.46 Low Density Lipoprotein (LDL) 1.7 Triglycerides 2.05 Glucose 4.8 Creatinine 108 Ferritin 67 Thyroid Stimulating Hormone (TSH) 3.89 Urea 5.1 Vitamin B12 151 White blood cells 6.4 HFD_index 0.289900052396678 CRP (mg/L) 0.6 CXCL11 (pg/ml) 2221.5624600338 CCL11 (pg/ml) 93.8369388899731 IL17A (pg/ml) 0.804784239145902 IFN-gamma (pg/ml) 3.00045655804726 IL-10 (pg/ml) 0.322460829366758 IL-6 (pg/ml) 0.384803750986766 IL-8 (pg/ml) 16.3439376489788 TNF-alpha (pg/ml) 1.99168117760304 CD4 (%) 32.9 CD8 (%) 14.3 LPS (EU/ml) 30.826708320705 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190933 SAMN10636299 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.002 host_residential_stratification Community treatment Intervention time_point week0 host Homo sapiens isolate Stool age not applicable host_age 75 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex male tissue not applicable host_barthel_score 20 host_body_mass_index 32.8 collection_date 2015-11-02 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 32.8 Weight (kg) 111 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 125 Alkaline Phosphatase 65 ALT 43 AST 34 Billirubin 31 Cholesterol 4.2 High Density Lipoprotein(HDL) 1.38 Low Density Lipoprotein (LDL) 2 Triglycerides 1.77 Glucose 6.2 Creatinine 103 Ferritin 93 Thyroid Stimulating Hormone (TSH) 3.98 Urea 3.5 Vitamin B12 194 White blood cells 6.1 HFD_index 0.325274489805184 CRP (mg/L) 0.7 CXCL11 (pg/ml) 1996.82330176247 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.754843052019322 IFN-gamma (pg/ml) 2.52719595297678 IL-10 (pg/ml) 0.32304058683955 IL-6 (pg/ml) 0.412385132845639 IL-8 (pg/ml) 72.7658278152946 TNF-alpha (pg/ml) 2.63146837682322 CD4 (%) 41.6 CD8 (%) 9.46 LPS (EU/ml) 30.7917375795584 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190934 SAMN10636547 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id YH.025 host_residential_stratification YoungHealthy treatment Intervention time_point week13 host Homo sapiens isolate Stool age not applicable host_age 53 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score not collected host_body_mass_index 29.6 collection_date 2016-05-04 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 29.6 Weight (kg) 73 Appendix A - Charlson co-morbidity not collected Appendix B - Barthel Score not collected Appendix C - FIM not collected Alkaline Phosphatase 82 ALT 35 AST 27 Billirubin 11 Cholesterol 6.2 High Density Lipoprotein(HDL) 1.25 Low Density Lipoprotein (LDL) 3.9 Triglycerides 2.37 Glucose 4.4 Creatinine 65 Ferritin 127 Thyroid Stimulating Hormone (TSH) 0.95 Urea 6.1 Vitamin B12 200 White blood cells 5 HFD_index 0.472287062925255 CRP (mg/L) 1.4 CXCL11 (pg/ml) 1.44536274481948 CCL11 (pg/ml) 3.00474022191751 IL17A (pg/ml) 0 IFN-gamma (pg/ml) 2.60292742604762 IL-10 (pg/ml) 0.145747909653868 IL-6 (pg/ml) 0.301975522984186 IL-8 (pg/ml) 8.95658419654935 TNF-alpha (pg/ml) 1.89588014766653 CD4 (%) 39.1 CD8 (%) 14.7 LPS (EU/ml) 7.0327868852459 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190935 SAMN10636297 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.001 host_residential_stratification Community treatment Intervention time_point week26 host Homo sapiens isolate Stool age not applicable host_age 76 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 19.9 collection_date 2016-05-11 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 19.9 Weight (kg) 53.5 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 89 ALT 23 AST 26 Billirubin 10 Cholesterol 4.9 High Density Lipoprotein(HDL) 1.77 Low Density Lipoprotein (LDL) 2.8 Triglycerides 0.55 Glucose 4.7 Creatinine 53 Ferritin 83 Thyroid Stimulating Hormone (TSH) 4.03 Urea 6 Vitamin B12 322 White blood cells 6.2 HFD_index 0.521346236687825 CRP (mg/L) 0.3 CXCL11 (pg/ml) 2261.80397457766 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.797574058146114 IFN-gamma (pg/ml) 3.53711486391887 IL-10 (pg/ml) 0.0966952880166925 IL-6 (pg/ml) 0.153861740556192 IL-8 (pg/ml) 14.7576656081221 TNF-alpha (pg/ml) 1.33849665749281 CD4 (%) 29.5 CD8 (%) 46.9 LPS (EU/ml) 30.71 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut SRS4190936 SAMN10636298 408170 human gut metagenome bioproject 511459 PRJNA511459 host_subject_id EC.001 host_residential_stratification Community treatment Intervention time_point week32 host Homo sapiens isolate Stool age not applicable host_age 76 biomaterial_provider APC Microbiome Ireland sex not applicable host_sex female tissue not applicable host_barthel_score 20 host_body_mass_index 20 collection_date 2016-06-21 env_broad_scale human-gut env_local_scale human-gut env_package human-gut env_medium human-gut host_body_product Stool ethnicity Irish geo_loc_name Ireland: Cork lat_lon 51.8820 N 8.5107 W body_mass_index 20 Weight (kg) 53.8 Appendix A - Charlson co-morbidity 0 Appendix B - Barthel Score 20 Appendix C - FIM 126 Alkaline Phosphatase 87 ALT 23 AST 30 Billirubin 11 Cholesterol 5.1 High Density Lipoprotein(HDL) 1.83 Low Density Lipoprotein (LDL) 3.1 Triglycerides 0.46 Glucose 4.9 Creatinine 53 Ferritin 66 Thyroid Stimulating Hormone (TSH) 3.64 Urea 5.7 Vitamin B12 265 White blood cells 6.2 HFD_index 0.520964126189472 CRP (mg/L) not collected CXCL11 (pg/ml) 1951.02421770177 CCL11 (pg/ml) 0 IL17A (pg/ml) 0.995684686002394 IFN-gamma (pg/ml) 7.36642229983748 IL-10 (pg/ml) 0.113844747920876 IL-6 (pg/ml) 0.238480993716396 IL-8 (pg/ml) 9.90289574188301 TNF-alpha (pg/ml) 1.46493085342381 CD4 (%) 25.9 CD8 (%) 38.5 LPS (EU/ml) 30.91 BioSampleModel MIMS.me BioSampleModel MIGS/MIMS/MIMARKS.human-gut