<?xml version="1.0" encoding="UTF-8"?>
<STUDY_SET xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <STUDY center_name="GEO" alias="GSE124745" accession="SRP176442">
    <IDENTIFIERS>
      <PRIMARY_ID>SRP176442</PRIMARY_ID>
      <EXTERNAL_ID namespace="BioProject" label="primary">PRJNA513317</EXTERNAL_ID>
      <EXTERNAL_ID namespace="GEO">GSE124745</EXTERNAL_ID>
    </IDENTIFIERS>
    <DESCRIPTOR>
      <STUDY_TITLE>The Tug1 locus is required for male fertility and comprised of DNA, RNA and Protein regulatory elements</STUDY_TITLE>
      <STUDY_TYPE existing_study_type="Transcriptome Analysis"/>
      <STUDY_ABSTRACT>We have sequenced mouse embryonic fibroblasts (MEFs) and 6 organs (testes, prostate, liver, heart, spleen, and eye) harvested from adult male wild type and Tug1 knockout (Tug1_tm1.1Vlcg) mice in a C57BL/6J/129S6 (N3-C57BL/6J, no Neo) background.  Additional sequencing was done on the testes of a Tug1 rescue mouse, which contains a doxycycline inducible allele for Tug1 (tg(Tug1)) and CAGs-rtTA3 in the Tug1 knockout background (Tug1_tmn1.1Vlcg). Overall design: Comparison between wild type and Tug1 knockout (Tug1_tm1.1Vlcg) organs and primary cell transcriptomes. Additional comparisons of the transcriptomes of wildtype, knockout, and rescue testes.</STUDY_ABSTRACT>
      <CENTER_PROJECT_NAME>GSE124745</CENTER_PROJECT_NAME>
    </DESCRIPTOR>
    <STUDY_LINKS>
      <STUDY_LINK>
        <XREF_LINK>
          <DB>pubmed</DB>
          <ID>32894169</ID>
        </XREF_LINK>
      </STUDY_LINK>
    </STUDY_LINKS>
  </STUDY>
</STUDY_SET>
