GSM3561843: 10-26 Control myeloid; Homo sapiens; RNA-Seq

SRX5247796 GSM3561843 GSM3561843: 10-26 Control myeloid; Homo sapiens; RNA-Seq SRP179061 SRS4250042 GSM3561843 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561843 GSM3561843 GEO Accession GSM3561843 SRX5247797 GSM3561844 GSM3561844: 02-01 Control endothelial; Homo sapiens; RNA-Seq SRP179061 SRS4250043 GSM3561844 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561844 GSM3561844 GEO Accession GSM3561844 SRX5247798 GSM3561845 GSM3561845: 10-63 Control neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250044 GSM3561845 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561845 GSM3561845 GEO Accession GSM3561845 SRX5247799 GSM3561846 GSM3561846: 06-26 AD neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250045 GSM3561846 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561846 GSM3561846 GEO Accession GSM3561846 SRX5247800 GSM3561847 GSM3561847: 13-40 Control myeloid; Homo sapiens; RNA-Seq SRP179061 SRS4250046 GSM3561847 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561847 GSM3561847 GEO Accession GSM3561847 SRX5247801 GSM3561848 GSM3561848: 06-26 AD myeloid; Homo sapiens; RNA-Seq SRP179061 SRS4250047 GSM3561848 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561848 GSM3561848 GEO Accession GSM3561848 SRX5247802 GSM3561849 GSM3561849: 10-70 Control myeloid; Homo sapiens; RNA-Seq SRP179061 SRS4250048 GSM3561849 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561849 GSM3561849 GEO Accession GSM3561849 SRX5247803 GSM3561850 GSM3561850: 07-04 Control endothelial; Homo sapiens; RNA-Seq SRP179061 SRS4250049 GSM3561850 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561850 GSM3561850 GEO Accession GSM3561850 SRX5247804 GSM3561851 GSM3561851: 04-54 AD endothelial; Homo sapiens; RNA-Seq SRP179061 SRS4250050 GSM3561851 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561851 GSM3561851 GEO Accession GSM3561851 SRX5247805 GSM3561852 GSM3561852: 07-28 Control neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250051 GSM3561852 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561852 GSM3561852 GEO Accession GSM3561852 SRX5247806 GSM3561853 GSM3561853: 04-54 AD neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250052 GSM3561853 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561853 GSM3561853 GEO Accession GSM3561853 SRX5247807 GSM3561854 GSM3561854: 13-74 AD neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250053 GSM3561854 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561854 GSM3561854 GEO Accession GSM3561854 SRX5247808 GSM3561855 GSM3561855: 13-49 Control endothelial; Homo sapiens; RNA-Seq SRP179061 SRS4250055 GSM3561855 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561855 GSM3561855 GEO Accession GSM3561855 SRX5247809 GSM3561856 GSM3561856: 02-01 Control astrocyte; Homo sapiens; RNA-Seq SRP179061 SRS4250054 GSM3561856 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561856 GSM3561856 GEO Accession GSM3561856 SRX5247810 GSM3561857 GSM3561857: 10-70 Control astrocyte; Homo sapiens; RNA-Seq SRP179061 SRS4250056 GSM3561857 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561857 GSM3561857 GEO Accession GSM3561857 SRX5247811 GSM3561858 GSM3561858: 08-55 Control neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250057 GSM3561858 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561858 GSM3561858 GEO Accession GSM3561858 SRX5247812 GSM3561859 GSM3561859: 09-35 Control neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250058 GSM3561859 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561859 GSM3561859 GEO Accession GSM3561859 SRX5247813 GSM3561860 GSM3561860: 11-98 Control endothelial; Homo sapiens; RNA-Seq SRP179061 SRS4250059 GSM3561860 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561860 GSM3561860 GEO Accession GSM3561860 SRX5247814 GSM3561861 GSM3561861: 11-105 AD neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250060 GSM3561861 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561861 GSM3561861 GEO Accession GSM3561861 SRX5247815 GSM3561862 GSM3561862: 13-49 Control neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250061 GSM3561862 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561862 GSM3561862 GEO Accession GSM3561862 SRX5247816 GSM3561863 GSM3561863: 05-58 AD myeloid; Homo sapiens; RNA-Seq SRP179061 SRS4250092 GSM3561863 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561863 GSM3561863 GEO Accession GSM3561863 SRX5247817 GSM3561864 GSM3561864: 05-58 AD neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250093 GSM3561864 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561864 GSM3561864 GEO Accession GSM3561864 SRX5247818 GSM3561865 GSM3561865: 10-80 AD endothelial; Homo sapiens; RNA-Seq SRP179061 SRS4250094 GSM3561865 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561865 GSM3561865 GEO Accession GSM3561865 SRX5247819 GSM3561866 GSM3561866: 10-22 Control neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250096 GSM3561866 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561866 GSM3561866 GEO Accession GSM3561866 SRX5247820 GSM3561867 GSM3561867: 13-66 AD neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250095 GSM3561867 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561867 GSM3561867 GEO Accession GSM3561867 SRX5247821 GSM3561868 GSM3561868: 10-63 Control endothelial; Homo sapiens; RNA-Seq SRP179061 SRS4250097 GSM3561868 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561868 GSM3561868 GEO Accession GSM3561868 SRX5247822 GSM3561869 GSM3561869: 09-20 Control neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250098 GSM3561869 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561869 GSM3561869 GEO Accession GSM3561869 SRX5247823 GSM3561870 GSM3561870: 00-54 AD astrocyte; Homo sapiens; RNA-Seq SRP179061 SRS4250099 GSM3561870 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561870 GSM3561870 GEO Accession GSM3561870 SRX5247824 GSM3561871 GSM3561871: 02-01 Control neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250100 GSM3561871 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561871 GSM3561871 GEO Accession GSM3561871 SRX5247825 GSM3561872 GSM3561872: 10-80 AD astrocyte; Homo sapiens; RNA-Seq SRP179061 SRS4250101 GSM3561872 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561872 GSM3561872 GEO Accession GSM3561872 SRX5247826 GSM3561873 GSM3561873: 03-63 Control neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250102 GSM3561873 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561873 GSM3561873 GEO Accession GSM3561873 SRX5247827 GSM3561874 GSM3561874: 03-63 Control endothelial; Homo sapiens; RNA-Seq SRP179061 SRS4250103 GSM3561874 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561874 GSM3561874 GEO Accession GSM3561874 SRX5247828 GSM3561875 GSM3561875: 02-27 Control endothelial; Homo sapiens; RNA-Seq SRP179061 SRS4250104 GSM3561875 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561875 GSM3561875 GEO Accession GSM3561875 SRX5247829 GSM3561876 GSM3561876: 03-59 AD endothelial; Homo sapiens; RNA-Seq SRP179061 SRS4250105 GSM3561876 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561876 GSM3561876 GEO Accession GSM3561876 SRX5247830 GSM3561877 GSM3561877: 03-59 AD myeloid; Homo sapiens; RNA-Seq SRP179061 SRS4250106 GSM3561877 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561877 GSM3561877 GEO Accession GSM3561877 SRX5247831 GSM3561878 GSM3561878: 08-55 Control endothelial; Homo sapiens; RNA-Seq SRP179061 SRS4250107 GSM3561878 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561878 GSM3561878 GEO Accession GSM3561878 SRX5247832 GSM3561879 GSM3561879: 03-15 Control astrocyte; Homo sapiens; RNA-Seq SRP179061 SRS4250108 GSM3561879 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561879 GSM3561879 GEO Accession GSM3561879 SRX5247833 GSM3561880 GSM3561880: 04-54 AD astrocyte; Homo sapiens; RNA-Seq SRP179061 SRS4250109 GSM3561880 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561880 GSM3561880 GEO Accession GSM3561880 SRX5247834 GSM3561881 GSM3561881: 00-54 AD neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250110 GSM3561881 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561881 GSM3561881 GEO Accession GSM3561881 SRX5247835 GSM3561882 GSM3561882: 07-04 Control myeloid; Homo sapiens; RNA-Seq SRP179061 SRS4250111 GSM3561882 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561882 GSM3561882 GEO Accession GSM3561882 SRX5247836 GSM3561883 GSM3561883: 07-15 AD neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250112 GSM3561883 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561883 GSM3561883 GEO Accession GSM3561883 SRX5247837 GSM3561884 GSM3561884: 14-29 AD myeloid; Homo sapiens; RNA-Seq SRP179061 SRS4250113 GSM3561884 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561884 GSM3561884 GEO Accession GSM3561884 SRX5247838 GSM3561885 GSM3561885: 11-98 Control astrocyte; Homo sapiens; RNA-Seq SRP179061 SRS4250114 GSM3561885 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561885 GSM3561885 GEO Accession GSM3561885 SRX5247839 GSM3561886 GSM3561886: 04-54 AD myeloid; Homo sapiens; RNA-Seq SRP179061 SRS4250115 GSM3561886 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561886 GSM3561886 GEO Accession GSM3561886 SRX5247840 GSM3561887 GSM3561887: 07-04 Control neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250116 GSM3561887 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561887 GSM3561887 GEO Accession GSM3561887 SRX5247841 GSM3561888 GSM3561888: 11-105 AD myeloid; Homo sapiens; RNA-Seq SRP179061 SRS4250117 GSM3561888 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561888 GSM3561888 GEO Accession GSM3561888 SRX5247842 GSM3561889 GSM3561889: 04-44 AD neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250118 GSM3561889 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561889 GSM3561889 GEO Accession GSM3561889 SRX5247843 GSM3561890 GSM3561890: 06-26 AD endothelial; Homo sapiens; RNA-Seq SRP179061 SRS4250119 GSM3561890 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561890 GSM3561890 GEO Accession GSM3561890 SRX5247844 GSM3561891 GSM3561891: 14-29 AD endothelial; Homo sapiens; RNA-Seq SRP179061 SRS4250120 GSM3561891 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561891 GSM3561891 GEO Accession GSM3561891 SRX5247845 GSM3561892 GSM3561892: 07-20 AD neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250121 GSM3561892 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561892 GSM3561892 GEO Accession GSM3561892 SRX5247846 GSM3561893 GSM3561893: 10-70 Control neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250122 GSM3561893 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561893 GSM3561893 GEO Accession GSM3561893 SRX5247847 GSM3561894 GSM3561894: 02-27 Control astrocyte; Homo sapiens; RNA-Seq SRP179061 SRS4250123 GSM3561894 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561894 GSM3561894 GEO Accession GSM3561894 SRX5247848 GSM3561895 GSM3561895: 10-26 Control endothelial; Homo sapiens; RNA-Seq SRP179061 SRS4250124 GSM3561895 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561895 GSM3561895 GEO Accession GSM3561895 SRX5247849 GSM3561896 GSM3561896: 03-15 Control neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250125 GSM3561896 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561896 GSM3561896 GEO Accession GSM3561896 SRX5247850 GSM3561897 GSM3561897: 05-10 Control endothelial; Homo sapiens; RNA-Seq SRP179061 SRS4250126 GSM3561897 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561897 GSM3561897 GEO Accession GSM3561897 SRX5247851 GSM3561898 GSM3561898: 07-04 Control astrocyte; Homo sapiens; RNA-Seq SRP179061 SRS4250127 GSM3561898 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561898 GSM3561898 GEO Accession GSM3561898 SRX5247852 GSM3561899 GSM3561899: 13-47 AD astrocyte; Homo sapiens; RNA-Seq SRP179061 SRS4250128 GSM3561899 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561899 GSM3561899 GEO Accession GSM3561899 SRX5247853 GSM3561900 GSM3561900: 13-54 AD neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250129 GSM3561900 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561900 GSM3561900 GEO Accession GSM3561900 SRX5247854 GSM3561901 GSM3561901: 00-54 AD myeloid; Homo sapiens; RNA-Seq SRP179061 SRS4250130 GSM3561901 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561901 GSM3561901 GEO Accession GSM3561901 SRX5247855 GSM3561902 GSM3561902: 13-40 Control neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250132 GSM3561902 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561902 GSM3561902 GEO Accession GSM3561902 SRX5247856 GSM3561903 GSM3561903: 11-38 AD neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250131 GSM3561903 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561903 GSM3561903 GEO Accession GSM3561903 SRX5247857 GSM3561904 GSM3561904: 11-98 Control neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250134 GSM3561904 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561904 GSM3561904 GEO Accession GSM3561904 SRX5247858 GSM3561905 GSM3561905: 05-10 Control astrocyte; Homo sapiens; RNA-Seq SRP179061 SRS4250133 GSM3561905 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561905 GSM3561905 GEO Accession GSM3561905 SRX5247859 GSM3561906 GSM3561906: 05-10 Control neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250135 GSM3561906 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561906 GSM3561906 GEO Accession GSM3561906 SRX5247860 GSM3561907 GSM3561907: 13-47 AD neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250136 GSM3561907 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561907 GSM3561907 GEO Accession GSM3561907 SRX5247861 GSM3561908 GSM3561908: 14-29 AD neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250137 GSM3561908 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561908 GSM3561908 GEO Accession GSM3561908 SRX5247862 GSM3561909 GSM3561909: 11-105 AD endothelial; Homo sapiens; RNA-Seq SRP179061 SRS4250138 GSM3561909 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561909 GSM3561909 GEO Accession GSM3561909 SRX5247863 GSM3561910 GSM3561910: 02-27 Control neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250139 GSM3561910 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561910 GSM3561910 GEO Accession GSM3561910 SRX5247864 GSM3561911 GSM3561911: 10-22 Control myeloid; Homo sapiens; RNA-Seq SRP179061 SRS4250140 GSM3561911 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561911 GSM3561911 GEO Accession GSM3561911 SRX5247865 GSM3561912 GSM3561912: 03-15 Control endothelial; Homo sapiens; RNA-Seq SRP179061 SRS4250142 GSM3561912 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561912 GSM3561912 GEO Accession GSM3561912 SRX5247866 GSM3561913 GSM3561913: 05-10 Control myeloid; Homo sapiens; RNA-Seq SRP179061 SRS4250141 GSM3561913 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561913 GSM3561913 GEO Accession GSM3561913 SRX5247867 GSM3561914 GSM3561914: 10-80 AD myeloid; Homo sapiens; RNA-Seq SRP179061 SRS4250143 GSM3561914 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561914 GSM3561914 GEO Accession GSM3561914 SRX5247868 GSM3561915 GSM3561915: 03-59 AD neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250144 GSM3561915 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561915 GSM3561915 GEO Accession GSM3561915 SRX5247869 GSM3561916 GSM3561916: 10-80 AD neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250145 GSM3561916 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561916 GSM3561916 GEO Accession GSM3561916 SRX5247870 GSM3561917 GSM3561917: 11-98 Control myeloid; Homo sapiens; RNA-Seq SRP179061 SRS4250146 GSM3561917 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561917 GSM3561917 GEO Accession GSM3561917 SRX5247871 GSM3561918 GSM3561918: 02-01 Control myeloid; Homo sapiens; RNA-Seq SRP179061 SRS4250148 GSM3561918 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561918 GSM3561918 GEO Accession GSM3561918 SRX5247872 GSM3561919 GSM3561919: 10-26 Control astrocyte; Homo sapiens; RNA-Seq SRP179061 SRS4250147 GSM3561919 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561919 GSM3561919 GEO Accession GSM3561919 SRX5247873 GSM3561920 GSM3561920: 04-44 AD endothelial; Homo sapiens; RNA-Seq SRP179061 SRS4250150 GSM3561920 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561920 GSM3561920 GEO Accession GSM3561920 SRX5247874 GSM3561921 GSM3561921: 11-49 AD neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250149 GSM3561921 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561921 GSM3561921 GEO Accession GSM3561921 SRX5247875 GSM3561922 GSM3561922: 10-26 Control neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250151 GSM3561922 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561922 GSM3561922 GEO Accession GSM3561922 SRX5247876 GSM3561923 GSM3561923: 11-49 AD astrocyte; Homo sapiens; RNA-Seq SRP179061 SRS4250152 GSM3561923 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561923 GSM3561923 GEO Accession GSM3561923 SRX5247877 GSM3561924 GSM3561924: 07-28 Control myeloid; Homo sapiens; RNA-Seq SRP179061 SRS4250153 GSM3561924 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561924 GSM3561924 GEO Accession GSM3561924 SRX5247878 GSM3561925 GSM3561925: 02-27 Control myeloid; Homo sapiens; RNA-Seq SRP179061 SRS4250154 GSM3561925 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561925 GSM3561925 GEO Accession GSM3561925 SRX5247879 GSM3561926 GSM3561926: 10-63 Control astrocyte; Homo sapiens; RNA-Seq SRP179061 SRS4250155 GSM3561926 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561926 GSM3561926 GEO Accession GSM3561926 SRX5247880 GSM3561927 GSM3561927: 10-63 Control myeloid; Homo sapiens; RNA-Seq SRP179061 SRS4250156 GSM3561927 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561927 GSM3561927 GEO Accession GSM3561927 SRX5247881 GSM3561928 GSM3561928: 09-35 Control endothelial; Homo sapiens; RNA-Seq SRP179061 SRS4250157 GSM3561928 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561928 GSM3561928 GEO Accession GSM3561928 SRX5247882 GSM3561929 GSM3561929: 03-63 Control myeloid; Homo sapiens; RNA-Seq SRP179061 SRS4250158 GSM3561929 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561929 GSM3561929 GEO Accession GSM3561929 SRX5247883 GSM3561930 GSM3561930: 10-22 Control endothelial; Homo sapiens; RNA-Seq SRP179061 SRS4250159 GSM3561930 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561930 GSM3561930 GEO Accession GSM3561930 SRX5247884 GSM3561931 GSM3561931: 09-35 Control myeloid; Homo sapiens; RNA-Seq SRP179061 SRS4250160 GSM3561931 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561931 GSM3561931 GEO Accession GSM3561931 SRX5247885 GSM3561932 GSM3561932: 07-28 Control endothelial; Homo sapiens; RNA-Seq SRP179061 SRS4250161 GSM3561932 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561932 GSM3561932 GEO Accession GSM3561932 SRX5247886 GSM3561933 GSM3561933: 10-79 AD neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250162 GSM3561933 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561933 GSM3561933 GEO Accession GSM3561933 SRX5247887 GSM3561934 GSM3561934: 10-20 Control neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250163 GSM3561934 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561934 GSM3561934 GEO Accession GSM3561934 SRX5247888 GSM3561935 GSM3561935: 03-21 AD neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250164 GSM3561935 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561935 GSM3561935 GEO Accession GSM3561935 SRX5247889 GSM3561936 GSM3561936: 10-20 Control myeloid; Homo sapiens; RNA-Seq SRP179061 SRS4250165 GSM3561936 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561936 GSM3561936 GEO Accession GSM3561936 SRX5247890 GSM3561937 GSM3561937: 08-41 AD neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250166 GSM3561937 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561937 GSM3561937 GEO Accession GSM3561937 SRX5247891 GSM3561938 GSM3561938: 03-21 AD myeloid; Homo sapiens; RNA-Seq SRP179061 SRS4250167 GSM3561938 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561938 GSM3561938 GEO Accession GSM3561938 SRX5247892 GSM3561939 GSM3561939: 10-39 Control myeloid; Homo sapiens; RNA-Seq SRP179061 SRS4250168 GSM3561939 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561939 GSM3561939 GEO Accession GSM3561939 SRX5247893 GSM3561940 GSM3561940: 10-20 Control astrocyte; Homo sapiens; RNA-Seq SRP179061 SRS4250169 GSM3561940 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561940 GSM3561940 GEO Accession GSM3561940 SRX5247894 GSM3561941 GSM3561941: 08-90 Control endothelial; Homo sapiens; RNA-Seq SRP179061 SRS4250170 GSM3561941 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561941 GSM3561941 GEO Accession GSM3561941 SRX5247895 GSM3561942 GSM3561942: 04-33 AD myeloid; Homo sapiens; RNA-Seq SRP179061 SRS4250171 GSM3561942 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561942 GSM3561942 GEO Accession GSM3561942 SRX5247896 GSM3561943 GSM3561943: 03-21 AD endothelial; Homo sapiens; RNA-Seq SRP179061 SRS4250172 GSM3561943 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561943 GSM3561943 GEO Accession GSM3561943 SRX5247897 GSM3561944 GSM3561944: 10-39 Control astrocyte; Homo sapiens; RNA-Seq SRP179061 SRS4250173 GSM3561944 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561944 GSM3561944 GEO Accession GSM3561944 SRX5247898 GSM3561945 GSM3561945: 09-50 Control neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250175 GSM3561945 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561945 GSM3561945 GEO Accession GSM3561945 SRX5247899 GSM3561946 GSM3561946: 10-79 AD endothelial; Homo sapiens; RNA-Seq SRP179061 SRS4250174 GSM3561946 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561946 GSM3561946 GEO Accession GSM3561946 SRX5247900 GSM3561947 GSM3561947: 10-39 Control neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250176 GSM3561947 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561947 GSM3561947 GEO Accession GSM3561947 SRX5247901 GSM3561948 GSM3561948: 09-50 Control endothelial; Homo sapiens; RNA-Seq SRP179061 SRS4250178 GSM3561948 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561948 GSM3561948 GEO Accession GSM3561948 SRX5247902 GSM3561949 GSM3561949: 08-90 Control astrocyte; Homo sapiens; RNA-Seq SRP179061 SRS4250177 GSM3561949 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561949 GSM3561949 GEO Accession GSM3561949 SRX5247903 GSM3561950 GSM3561950: 08-90 Control neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250179 GSM3561950 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561950 GSM3561950 GEO Accession GSM3561950 SRX5247904 GSM3561951 GSM3561951: 04-33 AD astrocyte; Homo sapiens; RNA-Seq SRP179061 SRS4250180 GSM3561951 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561951 GSM3561951 GEO Accession GSM3561951 SRX5247905 GSM3561952 GSM3561952: 04-33 AD neuron; Homo sapiens; RNA-Seq SRP179061 SRS4250181 GSM3561952 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561952 GSM3561952 GEO Accession GSM3561952 SRX5247906 GSM3561953 GSM3561953: 08-41 AD endothelial; Homo sapiens; RNA-Seq SRP179061 SRS4250182 GSM3561953 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561953 GSM3561953 GEO Accession GSM3561953 SRX5247907 GSM3561954 GSM3561954: 10-39 Control endothelial; Homo sapiens; RNA-Seq SRP179061 SRS4250183 GSM3561954 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561954 GSM3561954 GEO Accession GSM3561954 SRX5247908 GSM3561955 GSM3561955: 03-21 AD astrocyte; Homo sapiens; RNA-Seq SRP179061 SRS4250184 GSM3561955 RNA-Seq TRANSCRIPTOMIC cDNA Frozen tissue was dissociated on ice as described in manuscript and ethanol-fixed single-positive cells were sorted for each of four cell type markers, Astrocyte (Gfap+), Endothelial (Cd31+), Myeloid (CD11b+) and Neuron (NeuN+). RNA was extracted and amplified using Nugen Ovation V2. Libraries were then sequenced and analyzed as described in manuscript. Illumina HiSeq 2500 gds 303561955 GSM3561955 GEO Accession GSM3561955